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List of works by Xin Qi

A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission.

scientific article

A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats

scientific article published in Nature Communications

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects

scientific article published on 26 March 2019

Acute inhibition of excessive mitochondrial fission after myocardial infarction prevents long-term cardiac dysfunction

scientific journal article

Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.

scientific article

Bacterial endotoxin induces STAT3 activation in the mouse brain

scientific article published on 01 October 2004

Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission

scientific article

Cisplatin-mediated upregulation of APE2 binding to MYH9 provokes mitochondrial fragmentation and acute kidney injury

scientific article published on 07 December 2020

Decreased expression of spine-associated Rap guanosine triphosphatase-activating protein (SPAR) in glutamate-treated primary hippocampal neurons

scientific article published on 23 May 2010

Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity.

scientific article

Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model.

scientific article published on 18 June 2016

Drp1 phosphorylation by MAPK1 causes mitochondrial dysfunction in cell culture model of Huntington's disease

scientific article

Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo

scientific article (publication date: July 2014)

Dynamin-related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-anchored Mitochondrial Fission Factor

scientific article

Edaravone protects against hypoxia/ischemia-induced endoplasmic reticulum dysfunction

scientific article

Forebrain neuronal specific ablation of p53 gene provides protection in a cortical ischemic stroke model.

scientific article published on 14 March 2015

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Induction of murine HRD1 in experimental cerebral ischemia.

scientific article published in November 2004

Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis.

scientific article

Inhibition of Drp1 hyperactivation reduces neuropathology and behavioral deficits in zQ175 knock-in mouse model of Huntington's disease

scholarly article by Yuanyuan Zhao published in December 2018

Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP

scientific article published on 13 September 2016

Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation

scientific article

Mitochondria: A Therapeutic Target for Parkinson's Disease?

scientific article

Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability

scientific article published on 23 February 2019

Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease

scientific article published on 04 December 2020

Potential biomarkers to follow the progression and treatment response of Huntington's disease.

scientific article

Role of the SNK-SPAR pathway in the development of Alzheimer's disease

scientific article published in March 2010

Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease

scientific article published on 06 September 2021

Sodium 4-phenylbutyrate protects against cerebral ischemic injury.

scientific article

Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission

scientific article published in Scientific Reports

Stress Granule Dysregulation in Amyotrophic Lateral Sclerosis

scientific article published on 17 November 2020

The effect of Chinese Jinzhida recipe on the hippocampus in a rat model of diabetes-associated cognitive decline ⬇️

scientific article published on July 6, 2013

The effects of the Chinese medicine ZiBu PiYin recipe on the hippocampus in a rat model of diabetes-associated cognitive decline: a proteomic analysis

scientific article published on 21 April 2011

Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy

scientific article

Using induced pluripotent stem cell neuronal models to study neurodegenerative diseases

scientific article published on 18 March 2019

VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease

scientific article published on 29 November 2016

VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease

scientific article published on 26 August 2016

eIF2α links mitochondrial dysfunction to dendritic degeneration.

scientific article published on 16 February 2017

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