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List of works by Hugo M. Botelho

A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic

scientific article published on 15 November 2017

A proteomic approach toward the selection of proteins with enhanced intrinsic conformational stability.

scientific article published in October 2006

Analysis of S100 oligomers and amyloids

scientific article published in January 2012

Biochemical and biophysical characterization of recombinant yeast proteasome maturation factor ump1.

scientific article

CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system

scientific article published on 01 February 2022

CFTR processing, trafficking and interactions

scientific article published on 31 October 2019

Exploring YAP1-centered networks linking dysfunctional CFTR to epithelial-mesenchymal transition

scientific article published on 02 May 2022

Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum.

scientific article published on 14 April 2019

Full Rescue of F508del-CFTR Processing and Function by CFTR Modulators Can Be Achieved by Removal of Two Regulatory Regions

scientific article published on 25 June 2020

Intrinsically disordered and aggregation prone regions underlie β-aggregation in S100 proteins

scientific article

Investigating Alternative Transport of Integral Plasma Membrane Proteins from the ER to the Golgi: Lessons from the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

scientific article published in January 2016

Metal ions modulate the folding and stability of the tumor suppressor protein S100A2.

scientific article published in March 2009

Natural and amyloid self-assembly of S100 proteins: structural basis of functional diversity.

scientific article

Protein traffic disorders: an effective high-throughput fluorescence microscopy pipeline for drug discovery.

scientific article published on 12 March 2015

R560S: A class II CFTR mutation that is not rescued by current modulators

scientific article published on 18 July 2018

Role of a novel disulfide bridge within the all-beta fold of soluble Rieske proteins.

scientific article published on 28 October 2009

S100A6 amyloid fibril formation is calcium-modulated and enhances superoxide dismutase-1 (SOD1) aggregation

scientific article

Structural Heterogeneity and Bioimaging of S100 Amyloid Assemblies

Structural reorganization renders enhanced metalloprotein stability

scientific article published on 06 September 2011

The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation.

scientific article

Transcriptome meta-analysis reveals common differential and global gene expression profiles in cystic fibrosis and other respiratory disorders and identifies CFTR regulators

scientific article published on 27 July 2015

Unravelling the antitumoral potential of novel bis(thiosemicarbazonato) Zn(II) complexes: structural and cellular studies

scientific article published on 24 November 2018

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