List of works - Danny T Huang

13C and 15N isotope effects for conversion of L-dihydroorotate to N-carbamyl-L-aspartate using dihydroorotase from hamster and Bacillus caldolyticus

scientific article published in June 2006

<scp>PTEN</scp> deficiency exposes a requirement for an <scp>ARF GTPase</scp> module for integrin‐dependent invasion in ovarian cancer

scientific article published in 2023

A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants

scientific article published on October 2017

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

scientific article

Activation of a primed RING E3-E2-ubiquitin complex by non-covalent ubiquitin

scientific article

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

scientific article

Breaking up with a kinky SUMO

scientific article published on 01 December 2006

Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation

scientific article

Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

scientific article

Crystallization of hamster dihydroorotase: involvement of a disulfide-linked tetrameric form.

scientific article

DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination

scientific article published on 21 August 2020

Divalent metal derivatives of the hamster dihydroorotase domain

scientific article published on 01 August 1999

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification

scientific article

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3

scientific article

Expression, purification, and characterization of the E1 for human NEDD8, the heterodimeric APPBP1-UBA3 complex

scientific article published on 01 January 2005

Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation

scientific article published on 11 July 2019

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.

scientific article published on 10 February 2008

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response

scientific article published in 2024

Single-Turnover RING/U-Box E3-Mediated Lysine Discharge Assays

scientific article published on 01 January 2018

Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.

scientific article

Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

scientific article published on 29 April 2020

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl

scientific article

Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases

scientific article published on 18 September 2020

Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B~ubiquitin complex

scientific article published in Journal of Biological Chemistry

Structural insights into the catalysis and regulation of E3 ubiquitin ligases

scientific article

Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension

scientific article published on 13 January 2022

Structure of the human histone chaperone FACT Spt16 N-terminal domain

scientific article

Structure-specific recognition protein-1 (SSRP1) is an elongated homodimer that binds histones.

scientific article

Synthesis and enzymic evaluation of 4-mercapto-6-oxo-1, 4-azaphosphinane-2-carboxylic acid 4-oxide as an inhibitor of mammalian dihydroorotase

scientific article published on 01 November 1998

The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1

scientific article

Thermodynamic analysis of catalysis by the dihydroorotases from hamster and Bacillus caldolyticus, as compared with the uncatalyzed reaction

scientific article published in July 2006

Ubiquitin-like protein activation.

scientific article published on March 2004

Ubiquitination Accomplished: E1 and E2 Enzymes Were Not Necessary.

scientific article published in June 2016

List of works by Danny T Huang

13C and 15N isotope effects for conversion of L-dihydroorotate to N-carbamyl-L-aspartate using dihydroorotase from hamster and Bacillus caldolyticus

<scp>PTEN</scp> deficiency exposes a requirement for an <scp>ARF GTPase</scp> module for integrin‐dependent invasion in ovarian cancer

A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

Activation of a primed RING E3-E2-ubiquitin complex by non-covalent ubiquitin

BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

Breaking up with a kinky SUMO

Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation

Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

Crystallization of hamster dihydroorotase: involvement of a disulfide-linked tetrameric form.

DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination

Divalent metal derivatives of the hamster dihydroorotase domain

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3

Expression, purification, and characterization of the E1 for human NEDD8, the heterodimeric APPBP1-UBA3 complex

Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response

Single-Turnover RING/U-Box E3-Mediated Lysine Discharge Assays

Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.

Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl

Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases

Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B~ubiquitin complex

Structural insights into the catalysis and regulation of E3 ubiquitin ligases

Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension

Structure of the human histone chaperone FACT Spt16 N-terminal domain

Structure-specific recognition protein-1 (SSRP1) is an elongated homodimer that binds histones.

Synthesis and enzymic evaluation of 4-mercapto-6-oxo-1, 4-azaphosphinane-2-carboxylic acid 4-oxide as an inhibitor of mammalian dihydroorotase

The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1

Thermodynamic analysis of catalysis by the dihydroorotases from hamster and Bacillus caldolyticus, as compared with the uncatalyzed reaction

Ubiquitin-like protein activation.

Ubiquitination Accomplished: E1 and E2 Enzymes Were Not Necessary.