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List of works by Juan Duarte

A novel role for small molecule glycomimetics in the protection against lipid-induced endothelial dysfunction: Involvement of Akt/eNOS and Nrf2/ARE signaling.

scientific article published on 20 August 2016

Activation of PPARβ/δ prevents hyperglycaemia-induced impairment of Kv7 channels and cAMP-mediated relaxation in rat coronary arteries.

scientific article published on 13 July 2016

Activation of Peroxisome Proliferator Activator Receptor β/δ Improves Endothelial Dysfunction and Protects Kidney in Murine Lupus

scientific article published on 27 February 2017

Activation of peroxisome proliferator-activated receptor-β/-δ (PPARβ/δ) prevents endothelial dysfunction in type 1 diabetic rats

scientific article published in August 2012

Aminophylline preferentially inhibits chloroethylclonidine-insensitive alpha-adrenoceptor-mediated contractions in rat aorta

scientific article

Antihypertensive Effects of Probiotics.

scientific article published on April 2017

Antihypertensive Effects of Virgin Olive Oil (Unfiltered) Low Molecular Weight Peptides with ACE Inhibitory Activity in Spontaneously Hypertensive Rats

scientific article published on 20 January 2020

Antihypertensive effects of oleuropein-enriched olive leaf extract in spontaneously hypertensive rats.

scientific article published on 23 November 2015

Antihypertensive effects of peroxisome proliferator-activated receptor-β activation in spontaneously hypertensive rats

scientific journal article

Antihypertensive effects of peroxisome proliferator-activated receptor-β/δ activation.

scientific article published on 23 November 2016

Antihypertensive effects of probiotics Lactobacillus strains in spontaneously hypertensive rats.

scientific article published on 10 August 2015

Cardiovascular effects of captopril and enalapril in obese Zucker rats

scientific article

Cardiovascular effects of isorhamnetin and quercetin in isolated rat and porcine vascular smooth muscle and isolated rat atria

scientific article published in April 2002

Cardiovascular effects of visnagin on rats

scientific article published on 01 February 2000

Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.

scientific article

Changes to the gut microbiota induced by losartan contributes to its antihypertensive effects

scientific article published on 27 December 2019

Chronic (-)-epicatechin improves vascular oxidative and inflammatory status but not hypertension in chronic nitric oxide-deficient rats.

scientific article published on 13 September 2011

Chronic administration of genistein improves endothelial dysfunction in spontaneously hypertensive rats: involvement of eNOS, caveolin and calmodulin expression and NADPH oxidase activity

scientific article published on 01 February 2007

Chronic hydroxychloroquine improves endothelial dysfunction and protects kidney in a mouse model of systemic lupus erythematosus

scientific article published on 19 May 2014

Chronic peroxisome proliferator-activated receptorβ/δ agonist GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity

scientific article published in September 2015

CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome.

scientific article

Development of urea and thiourea kynurenamine derivatives: synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors

scientific article

Different cardiovascular protective effects of quercetin administered orally or intraperitoneally in spontaneously hypertensive rats

scientific article published on 01 June 2012

Effect of tyrosine kinase and tyrosine phosphatase inhibitors on aortic contraction and induction of nitric oxide synthase

scientific article

Effects of (S)-nafenodone on 45Ca2+ fluxes and contractions in rat isolated vascular smooth muscle

scientific article published in February 1993

Effects of Quercetin in a Rat Model of Hemorrhagic Traumatic Shock and Reperfusion.

scientific article published on 20 December 2016

Effects of Visnagin on Cyclic Nucleotide Phosphodiesterases and Their Role in its Inhibitory Effects on Vascular Smooth Muscle Contraction

scientific article published in January 1999

Effects of aminophylline on contractions and 45Ca uptake in isolated rat vascular smooth muscle

scientific article

Effects of chronic chrysin treatment in spontaneously hypertensive rats.

scientific article published in September 2002

Effects of chronic quercetin treatment in experimental renovascular hypertension

scientific article published in February 2005

Effects of chronic quercetin treatment on antioxidant defence system and oxidative status of deoxycorticosterone acetate-salt-hypertensive rats

scientific article

Effects of chronic quercetin treatment on hepatic oxidative status of spontaneously hypertensive rats

scientific article

Effects of factor Xa on the expression of proteins in femoral arteries from type 2 diabetic patients.

scientific article

Effects of flavonoids on rat aortic smooth muscle contractility: structure-activity relationships

scientific article published on 01 March 1996

Effects of oleuropeoside in isolated guinea-pig atria

scientific article published on 01 August 1993

Effects of peroxisome proliferator-activated receptor-β activation in endothelin-dependent hypertension

scientific article published on 10 June 2013

Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil.

scientific article published in April 2004

Effects of the dietary flavonoid chrysin in isolated rat mesenteric vascular bed.

scientific article published on 28 October 2004

Endothelial nitric oxide production stimulated by the bioflavonoid chrysin in rat isolated aorta.

scientific article published on September 2005

Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries

scientific article

Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension

scientific article published in January 2012

Epicatechin: endothelial function and blood pressure.

scientific article published on 29 March 2012

Flavonols and cardiovascular disease ⬇️

scientific article published on September 15, 2010

Genistein restores caveolin-1 and AT-1 receptor expression and vascular function in large vessels of ovariectomized hypertensive rats

scientific article published in September 2007

Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.

scientific article published on 14 August 2008

Glucuronidated metabolites of the flavonoid quercetin do not auto-oxidise, do not generate free radicals and do not decrease nitric oxide bioavailability.

scientific article published on 16 May 2008

Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.

scientific article

Impact of Nutrition on Pulmonary Arterial Hypertension

scientific article published on 07 January 2020

In vivo vascular effects of genistein on a rat model of septic shock induced by lipopolysaccharide

scientific article published in September 2003

Increased Klk9 Urinary Excretion Is Associated to Hypertension-Induced Cardiovascular Damage and Renal Alterations

scientific article

Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats

scientific article published in August 2006

Increased pressor sensitivity to chronic nitric oxide deficiency in hyperthyroid rats

scientific article

Influence of thyroid state on cardiac and renal capillary density and glomerular morphology in rats.

scientific article published on 2 January 2013

Inhibitory effects of quercetin and staurosporine on phasic contractions in rat vascular smooth muscle

scientific article published in September 1994

Involvement of protein kinase C and Na+/K+-ATPase in the contractile response induced by myricetin in rat isolated aorta

scientific article published in February 2002

Involvement of protein kinase C in reduced relaxant responses to the NO/cyclic GMP pathway in piglet pulmonary arteries contracted by the thromboxane A2-mimetic U46619.

scientific article published in August 1997

Kv7 channels critically determine coronary artery reactivity: left-right differences and down-regulation by hyperglycaemia

scientific article published on 23 January 2015

Lack of beneficial metabolic effects of quercetin in adult spontaneously hypertensive rats.

scientific article

Lack of synergistic interaction between quercetin and catechin in systemic and pulmonary vascular smooth muscle

scientific article published on 10 December 2010

Modulation of nitric oxide by flavonoids.

scientific article

Mycophenolate Improves Brain-Gut Axis Inducing Remodeling of Gut Microbiota in DOCA-Salt Hypertensive Rats

scientific article published on 28 November 2020

New strategy of tacrolimus administration in animal model based on tacrolimus-loaded microspheres

scientific article

Nitric oxide (NO) scavenging and NO protecting effects of quercetin and their biological significance in vascular smooth muscle.

scientific article published in April 2004

PPARβ activation restores the high glucose-induced impairment of insulin signalling in endothelial cells

scientific article published on June 2014

Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase

scientific article published on 16 May 2007

Protective Effects of Probiotic Consumption in Cardiovascular Disease in Systemic Lupus Erythematosus

scientific article published on 05 November 2019

Protective effects of the angiotensin II type 1 (AT1) receptor blockade in low-renin deoxycorticosterone acetate (DOCA)-treated spontaneously hypertensive rats

scientific article published in March 2004

Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats.

scientific article published in September 2002

Pulmonary Arterial Hypertension Affects the Rat Gut Microbiome.

scientific article published on 26 June 2018

Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats

scientific article published in 2015

Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC.

scientific article published on 16 March 2008

Role of UCP2 in the protective effects of PPARβ/δ activation on lipopolysaccharide-induced endothelial dysfunction.

scientific article published on 11 May 2016

Role of endothelium-derived relaxing factors in adrenomedullin-induced vasodilation in the rat kidney

scientific article published in May 2002

Role of sex, gonadectomy and sex hormones in the development of nitric oxide inhibition-induced hypertension

scientific article

Role of the immune system in vascular function and blood pressure control induced by faecal microbiota transplantation in rats

scientific article published on 02 June 2019

SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging

scientific journal article

Soy isoflavones improve endothelial function in spontaneously hypertensive rats in an estrogen-independent manner: role of nitric-oxide synthase, superoxide, and cyclooxygenase metabolites

scientific article published on 15 June 2005

The flavonoid paradox: conjugation and deconjugation as key steps for the biological activity of flavonoids

scientific article published on 04 May 2012

The flavonoid quercetin induces acute vasodilator effects in healthy volunteers: correlation with beta-glucuronidase activity

scientific article published on 27 July 2014

The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells

scientific article published on 9 June 2006

The flavonoid quercetin reverses pulmonary hypertension in rats

scientific article

The probiotic Lactobacillus coryniformis CECT5711 reduces the vascular pro-oxidant and pro-inflammatory status in obese mice.

scientific article published on July 2014

Vascular and Central Activation of Peroxisome Proliferator-Activated Receptor-β Attenuates Angiotensin II-Induced Hypertension: Role of RGS-5.

scientific article

Vascular deconjugation of quercetin glucuronide: The flavonoid paradox revealed?

scientific article published on 7 October 2011

Vascular reactivity in chronic Goldblatt two kidney-one clip hypertensive rats

scientific article published on 01 August 1990

Vascular superoxide production by endothelin-1 requires Src non-receptor protein tyrosine kinase and MAPK activation.

scientific article published on 6 May 2010

Vasodilator effect of olive leaf

scientific article published on 01 October 1991

Vasodilator effects of quercetin in isolated rat vascular smooth muscle

scientific article published in August 1993

Vasodilator effects of visnagin in isolated rat vascular smooth muscle

scientific article published in November 1995

Vasodilatory effects of flavonoids in rat aortic smooth muscle. Structure-activity relationships

scientific article published in July 1993

Vasorelaxant effects of the bioflavonoid chrysin in isolated rat aorta

scientific article published in August 2001

Wine polyphenols improve endothelial function in large vessels of female spontaneously hypertensive rats

scientific article published on 7 February 2008

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