List of works - Rafael Couñago

A Glutathione-Dependent Detoxification System Is Required for Formaldehyde Resistance and Optimal Survival of Neisseria meningitidis in Biofilms

scientific article

AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae

scientific article published on 16 January 2014

An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability-activity trade-offs

scientific article

Chemical Space Exploration of Oxetanes

scientific article published on 02 November 2020

Cloning, expression and purification of kinase domains of cacao PR-1 receptor-like kinases

scientific article

Crystallization and preliminary X-ray analysis of the chemokine-binding protein from orf virus (Poxviridae)

scientific article

Distinctive conformation of minor site-specific nuclear localization signals bound to importin-α

scientific article

Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae

scientific article

Evolution of the B3 DNA binding superfamily: new insights into REM family gene diversification

scientific article

Experimental evolution of adenylate kinase reveals contrasting strategies toward protein thermostability

scientific article

Gene replacement of adenylate kinase in the gram-positive thermophile Geobacillus stearothermophilus disrupts adenine nucleotide homeostasis and reduces cell viability

scientific article published on 13 January 2005

Identification of potential inhibitors of casein kinase 2 alpha of <i>Plasmodium falciparum</i> with potent <i>in vitro</i> activity

scientific article published on 15 November 2023

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

scientific article

In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the Nek family of kinases

scientific article published on 08 December 2017

In vivo molecular evolution reveals biophysical origins of organismal fitness

scientific article published on 01 May 2006

Prokaryotic Substrate-Binding Proteins as Targets for Antimicrobial Therapies ⬇️

scientific article published on October 1, 2012

Structural Characterization of Maize SIRK1 Kinase Domain Reveals an Unusual Architecture of the Activation Segment.

scientific article

Structural basis of interaction of bipartite nuclear localization signal from Agrobacterium VirD2 with rice importin-α

scientific article

Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region

scientific article

Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations.

scientific article published on 8 August 2017

Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major

scientific article published on 12 October 2020

Structures of Orf Virus Chemokine Binding Protein in Complex with Host Chemokines Reveal Clues to Broad Binding Specificity

scientific article

The distribution of different classes of nuclear localization signals (NLSs) in diverse organisms and the utilization of the minor NLS-binding site inplantnuclear import factor importin-α.

scientific article

List of works by Rafael Couñago

A Glutathione-Dependent Detoxification System Is Required for Formaldehyde Resistance and Optimal Survival of Neisseria meningitidis in Biofilms

AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae

An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability-activity trade-offs

Chemical Space Exploration of Oxetanes

Cloning, expression and purification of kinase domains of cacao PR-1 receptor-like kinases

Crystallization and preliminary X-ray analysis of the chemokine-binding protein from orf virus (Poxviridae)

Distinctive conformation of minor site-specific nuclear localization signals bound to importin-α

Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae

Evolution of the B3 DNA binding superfamily: new insights into REM family gene diversification

Experimental evolution of adenylate kinase reveals contrasting strategies toward protein thermostability

Gene replacement of adenylate kinase in the gram-positive thermophile Geobacillus stearothermophilus disrupts adenine nucleotide homeostasis and reduces cell viability

Identification of potential inhibitors of casein kinase 2 alpha of <i>Plasmodium falciparum</i> with potent <i>in vitro</i> activity

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the Nek family of kinases

In vivo molecular evolution reveals biophysical origins of organismal fitness

Prokaryotic Substrate-Binding Proteins as Targets for Antimicrobial Therapies ⬇️

Structural Characterization of Maize SIRK1 Kinase Domain Reveals an Unusual Architecture of the Activation Segment.

Structural basis of interaction of bipartite nuclear localization signal from Agrobacterium VirD2 with rice importin-α

Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region

Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations.

Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major

Structures of Orf Virus Chemokine Binding Protein in Complex with Host Chemokines Reveal Clues to Broad Binding Specificity

The distribution of different classes of nuclear localization signals (NLSs) in diverse organisms and the utilization of the minor NLS-binding site inplantnuclear import factor importin-α.