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List of works by Angelo Poletti

17-AAG increases autophagic removal of mutant androgen receptor in spinal and bulbar muscular atrophy.

scientific article published on 9 September 2010

5 alpha-reductase activity in isolated and cultured neuronal and glial cells of the rat.

scientific article published in May 1990

5 alpha-reductase isozymes in the central nervous system

scientific article published in May 1998

5alpha-reductase isozymes and aromatase are differentially expressed and active in the androgen-independent human prostate cancer cell lines DU145 and PC3

scientific article published on 01 December 1999

A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.

scientific article published on 25 August 2016

A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae

scientific article published in May 1992

A presynaptically toxic secreted phospholipase A2 is internalized into motoneuron-like cells where it is rapidly translocated into the cytosol

scientific article published on 26 January 2008

A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases

scientific article published on 16 October 2010

ALS-related misfolded protein management in motor neurons and muscle cells

scientific article

Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy.

scientific article

Aggregation and proteasome: the case of elongated polyglutamine aggregation in spinal and bulbar muscular atrophy.

scientific article published on 15 June 2006

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins.

scientific article published on 29 September 2011

Androgen 5-alpha-reductase type 2 is highly expressed and active in rat spinal cord motor neurones

scientific article published in September 2003

Androgen Metabolism in Different Target Tissues ⬇️

scientific article published on January 1, 1990

Androgen receptor activation by polychlorinated biphenyls: epigenetic effects mediated by the histone demethylase Jarid1b.

scientific article published on August 2013

Androgen regulates neuritin mRNA levels in an in vivo model of steroid-enhanced peripheral nerve regeneration

scientific article published in May 2008

Androgen regulation of axon growth and neurite extension in motoneurons

scientific article

Androgen-induced neurite outgrowth is mediated by neuritin in motor neurones.

scientific article

Androgens affect muscle, motor neuron, and survival in a mouse model of SOD1-related amyotrophic lateral sclerosis

article

Autophagic and Proteasomal Mediated Removal of Mutant Androgen Receptor in Muscle Models of Spinal and Bulbar Muscular Atrophy

scientific article published on 20 August 2019

BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch.

scientific article

C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation

scientific article published on 18 November 2021

CAG repeat length in androgen receptor gene is not associated with amyotrophic lateral sclerosis.

scientific article published on 10 January 2012

Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy.

scientific article published on 28 June 2013

Combinatorial treatment for spinal muscular atrophy: An Editorial for 'Combined treatment with the histone deacetylase inhibitor LBH589 and a splice-switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atroph

scientific article published on 14 February 2020

Concurrent AFG3L2 and SPG7 mutations associated with syndromic parkinsonism and optic atrophy with aberrant OPA1 processing and mitochondrial network fragmentation

scientific article published on 10 October 2018

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis.

scientific article published on 2 July 2014

Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

scientific article published on 25 March 2013

Differential autophagy power in the spinal cord and muscle of transgenic ALS mice.

scientific article

Dihydrotestosterone decreases tumor necrosis factor-alpha and lipopolysaccharide-induced inflammatory response in human endothelial cells.

scientific article published on 29 November 2005

Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells

scientific article published on 30 August 2018

Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: implication for protein aggregation and immune response.

scientific article published on 20 October 2011

Dysregulation of axonal transport and motorneuron diseases.

scientific article published on February 2011

Effect of postnatal starvation on the 5 alpha-reductase activity of the brain and of the isolated myelin membranes

scientific article published in January 1989

Effect of suramin on the biological activity of the two isoforms of the rat 5 alpha-reductase

scientific article published on 01 August 1996

Enhanced Clearance of Neurotoxic Misfolded Proteins by the Natural Compound Berberine and Its Derivatives ⬇️

scientific article published on 13 May 2020

Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol.

scientific article published on 28 July 2010

Estrogens, Neuroinflammation, and Neurodegeneration.

scientific article published on 19 May 2016

Exome sequencing identifies variants in two genes encoding the LIM-proteins NRAP and FHL1 in an Italian patient with BAG3 myofibrillar myopathy.

scientific article published on 21 July 2016

FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

scientific article published on 01 April 2019

Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HSC70 expression is reduced in lymphomonocytes of sporadic ALS patients and contributes to TDP-43 accumulation

scientific article published on 30 October 2019

Human adipose-derived mesenchymal stem cells as a new model of spinal and bulbar muscular atrophy.

scientific article

Identification of type 1 5alpha-reductase in myelin membranes of male and female rat brain

scientific journal article

Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly

scientific article published on 18 July 2014

Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases.

scientific article published on 12 April 2017

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

scientific article

Kinetic properties of the 5 alpha-reductase of testosterone in the purified myelin, in the subcortical white matter and in the cerebral cortex of the male rat brain

scientific article published in January 1990

Loss-of-function mutations in the SIGMAR1 gene cause distal hereditary motor neuropathy by impairing ER-mitochondria tethering and Ca2+ signalling

scientific article published on 8 July 2016

Luteinizing hormone-releasing hormone agonists interfere with the stimulatory actions of epidermal growth factor in human prostatic cancer cell lines, LNCaP and DU 145

scientific article published on 01 November 1996

Modulators of estrogen receptor inhibit proliferation and migration of prostate cancer cells.

scientific article published on 31 October 2013

Multiple Roles of Transforming Growth Factor Beta in Amyotrophic Lateral Sclerosis

scientific article published on 16 June 2020

Muscle cells and motoneurons differentially remove mutant SOD1 causing familial amyotrophic lateral sclerosis

scientific article

Mutation of SOD1 in ALS: a gain of a loss of function

scientific article

Neuritin (cpg15) enhances the differentiating effect of NGF on neuronal PC12 cells

scientific article published in September 2007

Neuritin 1 promotes neuronal migration.

scientific article published on 5 December 2012

Nuclear Phospho-SOD1 Protects DNA from Oxidative Stress Damage in Amyotrophic Lateral Sclerosis

scientific article published on 22 May 2019

Pathological Proteins Are Transported by Extracellular Vesicles of Sporadic Amyotrophic Lateral Sclerosis Patients

scientific article published on 19 July 2018

Polyglutamine tract expansion of the androgen receptor in a motoneuronal model of spinal and bulbar muscular atrophy.

scientific article

Post-translational modifications of expanded polyglutamine proteins: impact on neurotoxicity.

scientific article published on April 2009

Presence of 5alpha-reductase isozymes and aromatase in human prostate cancer cells and in benign prostate hyperplastic tissue.

scientific article

Proteasomal and autophagic degradative activities in spinal and bulbar muscular atrophy.

scientific article published on 16 July 2010

Publisher Correction: Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.

scientific article

Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy

scientific article

Searching for the ideal SERM

scientific article published on 01 May 1999

Small heat shock proteins: multifaceted proteins with important implications for life

scientific article published on 13 February 2019

Steroid binding and metabolism in the luteinizing hormone-releasing hormone-producing neuronal cell line GT1-1.

scientific article published on December 1994

Synergic prodegradative activity of Bicalutamide and trehalose on the mutant androgen receptor responsible for spinal and bulbar muscular atrophy

scientific article

Tdp-25 Routing to Autophagy and Proteasome Ameliorates its Aggregation in Amyotrophic Lateral Sclerosis Target Cells

scientific article published in Scientific Reports

Testosterone 5 alpha-reductase activity in the rat brain is highly concentrated in white matter structures and in purified myelin sheaths of axons

scientific article published on 01 August 1988

Testosterone metabolism in brain cells and membranes

scientific article published on 01 January 1991

Testosterone metabolism in peripheral nerves: presence of the 5 alpha-reductase-3 alpha-hydroxysteroid-dehydrogenase enzymatic system in the sciatic nerve of adult and aged rats

scientific article published on 01 January 1990

Tetracycline-regulated gene expression in the NSC-34-tTA cell line for investigation of motor neuron diseases.

scientific article published on 24 August 2005

The 5 alpha-reductase activity of the subcortical white matter, the cerebral cortex, and the hypothalamus of the rat and of the mouse: possible sex differences and effect of castration

scientific article published on 01 April 1987

The Regulation of the Small Heat Shock Protein B8 in Misfolding Protein Diseases Causing Motoneuronal and Muscle Cell Death

scientific article published on 02 August 2019

The Role of Sex and Sex Hormones in Neurodegenerative Diseases

scientific article published on 01 April 2020

The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases.

scientific article

The Role of the Protein Quality Control System in SBMA.

scientific article

The anabolic/androgenic steroid nandrolone exacerbates gene expression modifications induced by mutant SOD1 in muscles of mice models of amyotrophic lateral sclerosis

scientific article published on 10 December 2011

The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits tumor necrosis factor alpha and lipopolysaccharide induced inflammatory response in human endothelial cells and in mice aorta

scientific article published on 19 May 2010

The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.

scientific article published on 27 July 2016

The growing world of small heat shock proteins: from structure to functions

scientific article published on 31 March 2017

The neurotoxicity of mutant proteins 20 years after the discovery of the first mutant gene involved in neurodegeneration. Foreword.

scientific article published in May 2012

The polyglutamine tract of androgen receptor: from functions to dysfunctions in motor neurons.

scientific article published on April 2004

The protein quality control system in motoneuron diseases

scientific article published on 12 June 2015

The role of dynein mediated transport in the clearance of misfolded proteins responsible for motoneuron diseases

scientific article published on 12 June 2015

The role of the polyglutamine tract in androgen receptor.

scientific article published on 11 September 2007

The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases.

scientific article published on 12 June 2017

The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells

scientific article published on 02 January 2017

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).

scientific article published on 22 June 2010

Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases

scientific article published on 10 March 2016

Transforming growth factor beta 1 signaling is altered in the spinal cord and muscle of amyotrophic lateral sclerosis mice and patients

scientific article published on 10 July 2019

Transient Expression of the 5α-Reductase Type 2 Isozyme in the Rat Brain in Late Fetal and Early Postnatal Life1 ⬇️

scientific article published on April 1, 1998

Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration

scientific article published on 05 November 2018

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