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List of works by Federico Bussolino

3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner

scientific article

A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

scientific article

A fluorescent one-dimensional photonic crystal for label-free biosensing based on BLOCH surface waves

scientific article published on 5 February 2013

A new computational approach to analyze human protein complexes and predict novel protein interactions.

scientific article

A peptide from the extracellular region of the synaptic protein α Neurexin stimulates angiogenesis and the vascular specific tyrosine kinase Tie2.

scientific article published on 26 February 2013

A possible role for nitric oxide in modulating the functional cyclosporine toxicity by arginine

scientific article published on 01 June 1995

A simulation environment for directional sensing as a phase separation process

scientific article published on 20 March 2007

A transient kinetic study between signaling proteins: the case of the MEK–ERK interaction

Acetylcholine-induced production of platelet-activating factor by human fetal brain cells in culture

scientific article published in December 1990

Activation of diacylglycerol kinase alpha is required for VEGF-induced angiogenic signaling in vitro

scientific article

Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells

scientific article

Aminopeptidase A is a functional target in angiogenic blood vessels

scientific article

An Electrical Impedance-Based Method for Quantitative Real-Time Analysis of Semaphorin-Elicited Endothelial Cell Collapse

scientific article

An anti-inflammatory protein secreted from the rat seminal vesicle epithelium inhibits the synthesis of platelet-activating factor and the release of arachidonic acid and prostacyclin.

scientific article published on September 1990

Angiogenesis: a balancing act between integrin activation and inhibition?

scientific article published on December 2009

Angiopoietin-2 expression in breast cancer correlates with lymph node invasion and short survival.

scientific article published on February 2003

Angiopoietin-like 7, a novel pro-angiogenetic factor over-expressed in cancer.

scientific article

Anti-tumor activity of cytokines against opportunistic vascular tumors in mice

scientific article published on 01 March 1996

BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS Mutant Colorectal Cancer

scientific article published on 3 May 2016

Besides adhesion: new perspectives of integrin functions in angiogenesis

scientific article published on 19 February 2008

Bioengineered tumoral microtissues recapitulate desmoplastic reaction of pancreatic cancer

scientific article published on December 2016

Bloch surface wave enhanced biosensor for the direct detection of Angiopoietin-2 tumor biomarker in human plasma.

scientific article published on 8 January 2018

Bromodomain inhibition exerts its therapeutic potential in malignant pleural mesothelioma by promoting immunogenic cell death and changing the tumor immune-environment.

scientific article published on 27 November 2017

CCL16 activates an angiogenic program in vascular endothelial cells.

scientific article published on 4 September 2003

Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein

scientific article

Characterization of the neuroligin gene family expression and evolution in zebrafish

scientific article

Class 3 semaphorin in angiogenesis and lymphangiogenesis.

scientific article published on 17 October 2013

Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function

scientific article (publication date: 24 July 2003)

Class 3 semaphorins: physiological vascular normalizing agents for anti‐cancer therapy ⬇️

scientific article published on February 1, 2013

Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma

scientific article published on 24 March 2010

Comparative genome analysis of the neurexin gene family in Danio rerio: insights into their functions and evolution

scientific article published on 13 October 2006

Consensus guidelines for the use and interpretation of angiogenesis assays

article

Cu(II) and Zn(II) complexes with hyaluronic acid and its sulphated derivative. Effect on the motility of vascular endothelial cells

scientific article published on 01 October 2000

Development of microcantilever-based biosensor array to detect Angiopoietin-1, a marker of tumor angiogenesis☆

scientific article published on 04 November 2009

Diacylglycerol kinase-alpha phosphorylation by Src on Y335 is required for activation, membrane recruitment and Hgf-induced cell motility.

scientific article

Dictyostelium cells produce platelet-activating factor in response to cAMP ⬇️

scientific article published on March 28, 1991

Differential regulation of neurexin at glutamatergic and GABAergic synapses ⬇️

scientific article published on April 4, 2013

Direct recruitment of CRK and GRB2 to VEGFR-3 induces proliferation, migration, and survival of endothelial cells through the activation of ERK, AKT, and JNK pathways

scientific article

Dynamic modules and heterogeneity of function: a lesson from tyrosine kinase receptors in endothelial cells

scientific article

Effect of leukocyte stimulation on rabbit immune complex glomerulonephritis

scientific article published on 01 December 1990

Effect of prostacyclin on platelet-activating factor induced rabbit platelet aggregation

scientific article published on 01 November 1980

Embryonic cleavage modeling as a computational approach to sphere packing problem.

scientific article published on 4 October 2006

Emerging lymphae for the fountain of life ⬇️

scientific article published on January 29, 2013

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.

scientific article

Expression of angiopoietin-1 in human glioblastomas regulates tumor-induced angiogenesis: in vivo and in vitro studies.

scientific article published on April 2001

Fluorescence anisotropy analysis of protein–antibody interaction

GM-CSF and phorbol esters modulate GM-CSF receptor expression by independent mechanisms

scientific article published on 01 July 1991

Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.

scientific article published on 16 December 2002

Gorham-Stout Syndrome: A Monocyte-Mediated Cytokine Propelled Disease

article

HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma

scientific article published on March 2002

HIV-1 Tat Protein Stimulates In Vivo Vascular Permeability and Lymphomononuclear Cell Recruitment

article

Human GM-CSF in vivo: identification of the target cells and of their kinetics of response.

scientific article published on January 1990

Human immunodeficiency virus transactivator protein (Tat) stimulates chemotaxis, calcium mobilization, and activation of human polymorphonuclear leukocytes: implications for Tat-mediated pathogenesis.

scientific article published on 8 November 2000

Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production

scientific article

Human lymphoblastoid cells produce extracellular matrix-degrading enzymes and induce endothelial cell proliferation, migration, morphogenesis, and angiogenesis.

scientific article published on January 1998

Human monocyte-derived and CD34+cell-derived dendritic cells express functional receptors for platelet activating factor

scientific article published on 01 November 1997

IL-12-dependent innate immunity arrests endothelial cells in G0-G1 phase by a p21(Cip1/Waf1)-mediated mechanism

scientific article published on 15 July 2012

Identification of CD36 molecular features required for its in vitro angiostatic activity

scientific article published on 21 July 2005

In vivo priming of human normal neutrophils by granulocyte-macrophage colony stimulating factor: effect on the production of platelet activating factor

scientific article published on 01 July 1990

Increased expression of alpha6 integrin in endothelial cells unveils a proangiogenic role for basement membrane

scientific article published on 22 June 2010

Inhibition of vascular endothelial growth factor receptor 2-mediated endothelial cell activation by Axl tyrosine kinase receptor

scientific article published on 26 October 2004

Insulin-like growth factor binding protein-3 is overexpressed in endothelial cells of mouse breast tumor vessels.

scientific article

Integration of microfluidic and cantilever technology for biosensing application in liquid environment

scientific article published on 5 August 2010

Integrin signaling and lung cancer.

scientific article published on 16 January 2010

Integrins team up with tyrosine kinase receptors and plexins to control angiogenesis

scientific article published on May 2008

Integrins: a flexible platform for endothelial vascular tyrosine kinase receptors

scientific article published on 03 April 2007

Interactions between endothelial cells and HIV-1.

scientific article

Interleukin 1 stimulates platelet activating factor production in cultured human endothelial cells

article

Intravascular release of platelet activating factor in children with sepsis

scientific article published on 01 December 1987

Involvement of a serine protease in the synthesis of platelet-activating factor by endothelial cells stimulated by tumor necrosis factor-α or interleukin-1α

scientific article published on 01 December 1994

Involvement of a serine protease, but not of neutrophil elastase, in tumor necrosis factor-induced lethal hepatitis and induction of platelet-activating factor

scientific article published in October 2001

Is there a case for PAF antagonists in the treatment of ischemic states?

scientific article published on January 1989

LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms.

scientific article published on 11 April 2009

Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity

scientific article published on 5 May 2016

Liver X receptor activation reduces angiogenesis by impairing lipid raft localization and signaling of vascular endothelial growth factor receptor-2.

scientific article

Loss of inhibitory semaphorin 3A (SEMA3A) autocrine loops in bone marrow endothelial cells of patients with multiple myeloma.

scientific article published on 09 May 2006

MATERNAL VASCULAR PROSTACYCLIN ACTIVITY IN PRE-ECLAMPSIA

scientific article published in The Lancet

MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.

scientific article

Mature endothelium and neurons are simultaneously derived from embryonic stem cells by 2D in vitro culture system.

scientific article published on October 2011

MicroRNA-mediated regulatory circuits: outlook and perspectives

scientific article published on 06 June 2017

Microenvironment drives the endothelial or neural fate of differentiating embryonic stem cells coexpressing neuropilin-1 and Flk-1.

scientific article

Middle T antigen-transformed endothelial cells exhibit an increased activity of nitric oxide synthase.

scientific article

Modeling human tumor angiogenesis in a three-dimensional culture system.

scientific article published on 7 March 2013

Modeling the early stages of vascular network assembly.

scientific article

Modulation of Angiopoietin 2 release from endothelial cells and angiogenesis by the synaptic protein Neuroligin 2

scientific article published on 04 May 2018

Multifaceted activities of transcription factor eb in cancer onset and progression

scientific article published on 30 November 2020

Naturally occurring anti-band-3 antibodies and complement together mediate phagocytosis of oxidatively stressed human erythrocytes.

scientific article

Nervous vascular parallels: axon guidance and beyond ⬇️

scientific article published on January 1, 2011

Neurexins and neuroligins: synapses look out of the nervous system

scientific article

Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrin

scientific article published on 23 May 2014

Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrin.

scientific article published in September 2014

Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.

scientific article

Neutropenia induced by platelet-activating factor (PAF-acether) released from neutrophils: the inhibitory effect of prostacyclin (PGI2).

scientific article published in December 1981

Nitrovasodilators inhibit thrombin-induced platelet-activating factor synthesis in human endothelial cells

scientific article published on 01 July 1992

Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings.

scientific article

On the Use of Stochastic Petri Nets in the Analysis of Signal Transduction Pathways for Angiogenesis Process

article

Osteopontin overexpression inhibits in vitro re-endothelialization via integrin engagement.

scientific article published on 23 April 2007

PDK1 regulates focal adhesion disassembly by modulating endocytosis of αvβ3 integrin

scientific article published on 14 January 2015

PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction.

scientific article

PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations.

scientific article published on 19 January 2018

Percolation, morphogenesis, and burgers dynamics in blood vessels formation

scientific article published on 17 March 2003

Platelet activating factor interaction with tumor necrosis factor and myocardial depressant factor in splanchnic artery occlusion shock

scientific article published in November 1992

Platelet activating factor is elevated in cerebral spinal fluid and plasma of patients with relapsing-remitting multiple sclerosis.

scientific article

Platelet activating factor produced in vitro by Kaposi's sarcoma cells induces and sustains in vivo angiogenesis

scientific article published on August 1995

Platelet-activating factor phosphatidate, but not platelet-activating factor, is a powerful calcium ionophore in the human red cell

scientific article published on 01 October 1984

Platelet-activating factor production by human fetal microglia. Effect of lipopolysaccharides and tumor necrosis factor-alpha.

scientific article published on February 1995

Platelet-activating factor-mediated contraction of rabbit lung strips: Pharmacologic modulation

scientific article published on 01 August 1983

Potential Diagnostic and Prognostic Role of Microenvironment in Malignant Pleural Mesothelioma

scientific article published on 09 May 2019

Priming of the vascular endothelial growth factor signaling pathway by thrombospondin-1, CD36, and spleen tyrosine kinase.

scientific article

Proliferative and migratory responses of murine microvascular endothelial cells to granulocyte‐colony‐stimulating factor ⬇️

scientific article published on April 1, 1993

Protein kinase D1 regulates VEGF-A-induced alphavbeta3 integrin trafficking and endothelial cell migration

scientific article published on 6 May 2010

Real-time monitoring of cell protrusion dynamics by impedance responses.

scientific article

Recent developments in the cell biology of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor: activities on endothelial cells.

scientific article

Recombinant AAV vector encoding human VEGF165 enhances wound healing.

scientific article

Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.

scientific article

Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

scientific article

Role of soluble mediators in angiogenesis

scientific article published on December 1996

Role of the microenvironment in the specification of endothelial progenitors derived from embryonic stem cells.

scientific article published on 04 January 2010

SPAD aptasensor for the detection of circulating protein biomarkers

scientific article published on 19 January 2015

Sema3F (Semaphorin 3F) Selectively Drives an Extraembryonic Proangiogenic Program.

scientific article published on 20 July 2017

Sema4D induces angiogenesis through Met recruitment by Plexin B1

scientific article

Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models

scientific article published on 05 October 2009

Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

scientific article published on 9 April 2012

Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages.

scientific article

Semaphoring vascular morphogenesis

scientific article

Semaphorins and tumor angiogenesis.

scientific article published on 06 March 2009

Semaphorins in cardiovascular medicine.

scientific article

Simplification of a complex signal transduction model using invariants and flow equivalent servers

article

Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores

scientific article

Small molecule approaches for promoting ischemic tissue vascularization

scientific article published on 01 August 2006

Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways

scientific article

Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1.

scientific article published on September 2005

Streptokinase induces intravascular release of platelet-activating factor in patients with acute myocardial infarction and stimulates its synthesis by cultured human endothelial cells.

scientific article

Symmetry breaking mechanism for epithelial cell polarization.

scientific article

Synergism Between Platelet Activating Factor and C-C Chemokines for Arachidonate Release in Human Monocytes

scientific article published on 01 March 1994

TFEB controls vascular development by regulating the proliferation of endothelial cells

article

Targeted dual-color silica nanoparticles provide univocal identification of micrometastases in preclinical models of colorectal cancer.

scientific article

Targeting oncogenic serine/threonine-protein kinase BRAF in cancer cells inhibits angiogenesis and abrogates hypoxia

scientific article published on 27 December 2011

Tat-induced platelet-activating factor synthesis contributes to the angiogenic effect of HIV-1 Tat

article

Temporal and spatial modulation of Rho GTPases during in vitro formation of capillary vascular network. Adherens junctions and myosin light chain as targets of Rac1 and RhoA.

scientific article published on 12 September 2003

The Neuronal Pentraxin-2 Pathway Is an Unrecognized Target in Human Neuroblastoma, Which Also Offers Prognostic Value in Patients.

scientific article published on 20 August 2015

The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling

scientific article

The V1/V2 loop of HIV-1 gp120 is necessary for Tat binding and consequent modulation of virus entry.

scientific article published on 31 July 2013

The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells.

scientific article

The biological basis for antiangiogenic therapy

scientific article published on 01 October 2000

The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination

scientific article

The miR-126 regulates angiopoietin-1 signaling and vessel maturation by targeting p85β.

scientific article

The molecular action of tumor necrosis factor-alpha

scientific article

The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions

scientific article

The synaptic proteins β-neurexin and neuroligin synergize with extracellular matrix-binding vascular endothelial growth factor a during zebrafish vascular development.

scientific article

Therapy for Cancer: Strategy of Combining Anti-Angiogenic and Target Therapies

scientific article published on 7 December 2017

Three-Dimensional In Vitro Assay of Endothelial Cell Invasion and Capillary Tube Morphogenesis

scientific article published on 01 January 2015

Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1

scientific article

Tumor necrosis factor alpha-induced angiogenesis depends on in situ platelet-activating factor biosynthesis.

scientific article

Tumor necrosis factor alters cytoskeletal organization and barrier function of endothelial cells

scientific article published in January 1991

Tumor necrosis factor induces contraction of mesangial cells and alters their cytoskeletons

scientific article published on 01 November 1990

Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells.

scientific article

Tumor-host interaction mediates the regression of BK virus-induced vascular tumors in mice: involvement of transforming growth factor-beta1.

scientific article published on 4 July 2003

Type I collagen limits VEGFR-2 signaling by a SHP2 protein-tyrosine phosphatase-dependent mechanism 1.

scientific article

Unraveling the influence of endothelial cell density on VEGF-A signaling

scientific article published on 17 April 2012

VEGF blockade enhances the antitumor effect of BRAFV600E inhibition.

scientific article published on 14 December 2016

Vascular endothelial growth factor-C stimulates the migration and proliferation of Kaposi's sarcoma cells.

scientific article published on September 1999

Vasculogenic potential of long term repopulating cord blood progenitors.

scientific article published on 18 June 2004

Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5

scientific article published on 04 June 2019

c-fos-induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro.

scientific article

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