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List of works by Paolo Armando Gagliardi

Activation of RSK by phosphomimetic substitution in the activation loop is prevented by structural constraints

scientific article published on 17 January 2020

Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype

scientific article published on 01 August 2020

Death for life: a path from apoptotic signaling to tissue-scale effects of apoptotic epithelial extrusion

scientific article published on 29 May 2019

Developmental Erk Signaling Illuminated

scientific article published on 01 February 2019

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.

scientific article

Increased expression of alpha6 integrin in endothelial cells unveils a proangiogenic role for basement membrane

scientific article published on 22 June 2010

Irreversible Activation of Rho-activated Kinases Resulted from Evolution of Proteolytic Sites within Disordered Regions in Coiled-coil Domain

scientific article published on 01 February 2019

MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.

scientific article

Modeling human tumor angiogenesis in a three-dimensional culture system.

scientific article published on 7 March 2013

PDK1 regulates focal adhesion disassembly by modulating endocytosis of αvβ3 integrin

scientific article published on 14 January 2015

PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction.

scientific article

PDK1: A signaling hub for cell migration and tumor invasion

scientific article published on 31 July 2015

PDK1: At the crossroad of cancer signaling pathways.

scientific article published on May 2017

PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations.

scientific article published on 19 January 2018

Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism.

scientific article published on 26 November 2015

Real-time monitoring of cell protrusion dynamics by impedance responses.

scientific article

Serine/Threonine Kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDK1) as a Key Regulator of Cell Migration and Cancer Dissemination.

scientific article published on 11 March 2017

The miR-126 regulates angiopoietin-1 signaling and vessel maturation by targeting p85β.

scientific article

Three-dimensional chemotaxis-driven aggregation of tumor cells

scientific article

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