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List of works by Tony Carr

14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast

scientific article published in July 1994

1st MRC Human Genetics Symposium: Maintenance of Genomic Stability

article

3D Printed Calcium Phosphate Cement (CPC) Scaffolds for Anti-Cancer Drug Delivery

scientific article published on 11 November 2020

A Rad3–Rad26 complex responds to DNA damage independently of other checkpoint proteins

scientific article published on 01 November 1999

A global profile of replicative polymerase usage

scientific article

A simple Cre-loxP method for chromosomal N-terminal tagging of essential and non-essential Schizosaccharomyces pombe genes

scientific article

A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway

scientific article

A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein

scientific article

A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage

scientific article

A winged helix domain in human MUS81 binds DNA and modulates the endonuclease activity of MUS81 complexes

scientific article

Additional vectors for PCR-based gene tagging in Saccharomyces cerevisiae and Schizosaccharomyces pombe using nourseothricin resistance

scientific article published in October 2005

An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.

scientific article

An essential role for dNTP homeostasis following CDK-induced replication stress

scientific article published on 25 March 2019

Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.

scientific article

Analysis of Replicative Polymerase Usage by Ribonucleotide Incorporation

scientific article

Analysis of a histone H2A variant from fission yeast: evidence for a role in chromosome stability.

scientific article published on December 1994

Analysis of radiation-sensitive mutants of fission yeast ⬇️

scientific article published on January 1, 1997

Analyzing the Response to Dysfunction Replication Forks Using the RTS1 Barrier System in Fission Yeast

scientific article published on 01 January 2015

Are sites with multiple single nucleotide variants in cancer genomes a consequence of drivers, hypermutable sites or sequencing errors?

scientific article published on 20 September 2016

Arrested replication fork processing: interplay between checkpoints and recombination

scientific article published on 6 April 2007

Assignment of ten DNA repair genes from Schizosaccharomyces pombe to chromosomal NotI restriction fragments

article

Atm-dependent interactions of a mammalian Chk1 homolog with meiotic chromosomes ⬇️

scientific article published on December 1, 1997

CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent resection

scientific article

CUL4B-deficiency in humans: understanding the clinical consequences of impaired Cullin 4-RING E3 ubiquitin ligase function

scientific article published on 23 February 2011

Caffeine-resistance in S. pombe: mutations in three novel caf genes increase caffeine tolerance and affect radiation sensitivity, fertility, and cell cycle

article

Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III

scientific article published on May 2002

Cell cycle co-ordination after too much rum.

scientific article published on May 1994

Cell cycle. Piecing together the p53 puzzle.

scientific article

Cell division defects of Schizosaccharomyces pombe liz1- mutants are caused by defects in pantothenate uptake

scientific article

Characterisation of a stably integrated expression system for exogenous protein expression in DT40.

scientific article

Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function

scientific article published on 01 July 1997

Checking That Replication Breakdown Is Not Terminal

scientific article published on 01 July 2002

Checkpoint policing by p53.

scientific article

Checkpoint responses to replication fork barriers

scientific article

Checkpoints Take the Next Step

scientific article published on 01 January 1996

Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements.

scientific article published on 27 February 2015

Checkpoints: How to Flag Up Double-Strand Breaks

article published in 2002

Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1

scientific article

Cloning Human DNA Repair Genes

article

Cloning and characterisation of the S. pombe rad15 gene, a homologue to the S. cerevisiae RAD3 and human ERCC2 genes ⬇️

scientific article published on June 11, 1992

Cloning and characterisation of therad9DNA repair gene fromSchizosaccharomyces pombe ⬇️

scientific article published on July 11, 1991

Cloning of caf1+, caf2+ and caf4+ from Schizosaccharomyces pombe: their involvement in multidrug resistance, UV and pH sensitivity

scientific article published in December 1998

Cloning the RAD51 homologue of Schizosaccharomyces pombe.

scientific article published on September 1993

Colony Polymerase Chain Reaction with Schizosaccharomyces pombe

scientific article published on 02 May 2016

Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres

scientific article

Construction and functional characterization of polyomavirus genomes that separately encode the three early proteins ⬇️

scientific article published on July 1, 1984

Control of cell cycle arrest by the Mec1sc/Rad3sp DNA structure checkpoint pathway.

scientific article published on February 1997

Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms

scientific article

Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1.

scientific article

Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions

scientific article published on 12 January 2009

Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrest

scientific article

DDK phosphorylates checkpoint clamp component Rad9 and promotes its release from damaged chromatin

scientific article

DNA checkpoints in fission yeast

scientific article

DNA damage, repair and the cell cycle

scientific article published on 01 January 1994

DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe

scientific article

DNA repair, genome stability and cancer: a historical perspective

scientific article published on 15 December 2015

DNA replication: failures and inverted fusions

scientific article published on 18 October 2011

DNA structure dependent checkpoints as regulators of DNA repair

scientific article

DNA structure-dependent checkpoints in model systems.

scientific article published on November 1997

Ddb1 controls genome stability and meiosis in fission yeast

scientific article published on April 2005

Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes

scientific article published on February 2002

Delineating the position of rad4+/cut5+ within the DNA-structure checkpoint pathways in Schizosaccharomyces pombe

scientific article

Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA.

scientific article published on January 2009

Duplication of ATR inhibits MyoD, induces aneuploidy and eliminates radiation-induced G1 arrest

scientific article

Evolutionary conservation of excision repair in Schizosaccharomyces pombe: evidence for a family of sequences related to the Saccharomyces cerevisiae RAD2 gene

scientific article

Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines ⬇️

scientific article published on July 1, 1983

Extraction of Chromosomal DNA from Schizosaccharomyces pombe.

scientific article

FindFoci: a focus detection algorithm with automated parameter training that closely matches human assignments, reduces human inconsistencies and increases speed of analysis

scientific article

Fission yeast genes involved in coupling mitosis to completion of DNA replication

article

Fission yeast wee1 protein kinase is not required for DMA damage-dependent mitotic arrest

scientific article published in Nature

GDSC SMLM: Single-molecule localisation microscopy software for ImageJ

scientific article published in 2022

Gene tagging and gene replacement using recombinase-mediated cassette exchange in Schizosaccharomyces pombe

scientific article published on 11 October 2007

Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1

scientific article published on 18 April 2007

Gross Chromosomal Rearrangements and Elevated Recombination at an Inducible Site-Specific Replication Fork Barrier

scientific article published on 01 June 2005

Homologous Recombination Restarts Blocked Replication Forks at the Expense of Genome Rearrangements by Template Exchange

scientific article published on 01 August 2010

Identification and functional analysis of TopBP1 and its homologs

scientific article

Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks.

scientific article published on 13 June 2016

Identifying Products of Recombinase-Mediated Cassette Exchange (RMCE) in Schizosaccharomyces pombe

scientific article published on 02 May 2016

Impediments to replication fork movement: stabilisation, reactivation and genome instability

scientific article published on 28 February 2013

Integrating DNA damage repair with the cell cycle

scientific article published on 24 March 2018

Interacting factors and cellular localization of SR protein-specific kinase Dsk1.

scientific article published on 6 June 2012

Involvement of Schizosaccharomyces pombe rrp1+ and rrp2+ in the Srs2- and Swi5/Sfr1-dependent pathway in response to DNA damage and replication inhibition

scientific article

Isolation of DNA structure-dependent checkpoint mutants in S. pombe

scientific article published on 01 January 1999

Isolation of the Schizosaccharomyces pombe RAD54 homologue, rhp54+, a gene involved in the repair of radiation damage and replication fidelity

article

LAMMER kinase Kic1 is involved in pre-mRNA processing.

scientific article published in July 2011

LETM1 haploinsufficiency causes mitochondrial defects in cells from humans with Wolf-Hirschhorn syndrome: implications for dissecting the underlying pathomechanisms in this condition

scientific article published on 13 March 2014

MOLECULAR BIOLOGY: Beginning at the End

scientific article published on 01 June 2003

Mapping ribonucleotides in genomic DNA and exploring replication dynamics by polymerase usage sequencing (Pu-seq).

scientific article

Molecular Genetic Tools and Techniques in Fission Yeast

scientific article published on 02 May 2016

Nearby inverted repeats fuse to generate acentric and dicentric palindromic chromosomes by a replication template exchange mechanism.

scientific article published on December 2009

Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.

scientific article

Optimisation of the Schizosaccharomyces pombe urg1 expression system

scientific article

PCNA ubiquitylation ensures timely completion of unperturbed DNA replication in fission yeast

scientific article

Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4TopBP1

scientific article

Polymerase δ replicates both strands after homologous recombination-dependent fork restart

scientific article

Possible methodologies for the detection and study of DNA sequence changes following mutagen exposure: magnetic enrichment in mutant DNA

scientific article published on 01 November 1990

Postreplication repair and PCNA modification in Schizosaccharomyces pombe

scientific article published on 26 April 2006

Preserving replication fork integrity and competence via the homologous recombination pathway

scientific article published on 25 August 2018

Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy

scientific article published on 8 August 2014

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast.

scientific article published on July 2012

RAD6-RAD18-RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light.

scientific article

Rad3-dependent phosphorylation of the checkpoint clamp regulates repair-pathway choice

scientific article published on 21 May 2007

Rad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast

scientific article

Radiation checkpoints in model systems

scientific article

Recombination-restarted replication makes inverted chromosome fusions at inverted repeats.

scientific article published on 25 November 2012

Regulation of gene expression at the fission yeast Schizosaccharomyces pombe urg1 locus

scientific article

Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

scientific article published on June 2010

Repair of cyclobutane pyrimidine dimers and 6-4 photoproducts in the fission yeast Schizosaccharomyces pombe

scientific article published on 01 November 1993

Replication fork arrest, recombination and the maintenance of ribosomal DNA stability

scientific article published on 29 July 2008

Replication stress and genome rearrangements: lessons from yeast models ⬇️

scientific article published on December 22, 2012

Replication stress-induced genome instability: the dark side of replication maintenance by homologous recombination

scientific article published on 30 April 2013

Requirement for DNA ligase IV during embryonic neuronal development

scientific article published on July 2011

Requirement of sequences outside the conserved kinase domain of fission yeast Rad3p for checkpoint control.

scientific article published on October 1999

Role of Schizosaccharomyces pombe RecQ Homolog, Recombination, and Checkpoint Genes in UV Damage Tolerance ⬇️

scientific article published on December 1, 1997

Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediates

scientific article

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

scientific article

Schizosaccharomyces pombe Cds1Chk2 regulates homologous recombination at stalled replication forks through the phosphorylation of recombination protein Rad60.

scientific article published on 15 September 2009

Schizosaccharomyces pombe DNA translocases Rrp1 and Rrp2 have distinct roles at centromeres and telomeres that ensure genome stability

scientific article published on 10 February 2020

Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination

scientific article

Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-links

scientific article

Set2 Methyltransferase Facilitates DNA Replication and Promotes Genotoxic Stress Responses through MBF-Dependent Transcription

scientific article published on September 2017

Smc5/6: a link between DNA repair and unidirectional replication?

scientific article published on 01 February 2008

Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated

scientific article published on 28 August 2013

Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools.

scientific article published on 20 March 2014

Splitting the ATM: distinct repair and checkpoint defects in ataxia–telangiectasia

scientific article published on 01 August 1998

Synthetic lethality between TP53 and ENDOD1

scientific article published on 23 May 2022

The 14-3-3 proteins encoded by the BMH1 and BMH2 genes are essential in the yeast Saccharomyces cerevisiae and can be replaced by a plant homologue

scientific article

The Antiresection Activity of the X Protein Encoded by Hepatitis Virus B

scientific article published on 11 April 2019

The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.

scientific article published on October 1996

The COP9/signalosome complex is conserved in fission yeast and has a role in S phase

scientific article published on 01 December 1999

The G2-phase DNA-damage checkpoint

scientific article (publication date: July 2000)

The Rad4(TopBP1) ATR-activation domain functions in G1/S phase in a chromatin-dependent manner

scientific article

The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis.

scientific article published in February 1995

The Schizosaccharomyces pombe rad3 checkpoint gene

scientific article

The Wee1 protein kinase regulates T14 phosphorylation of fission yeast Cdc2

scientific article

The cellular responses to DNA damage

article

The chk1 pathway is required to prevent mitosis following cell-cycle arrest at 'start'.

scientific article published in October 1995

The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast

scientific article published on 2 November 2013

The cytotoxicity of anthramycin to mutants ofSchizosaccharomyces pombedeficient in DNA damage responses

article

The extent of error-prone replication restart by homologous recombination is controlled by Exo1 and checkpoint proteins.

scientific article

The intra-S phase checkpoint targets Dna2 to prevent stalled replication forks from reversing.

scientific article published in June 2012

The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved

scientific article

The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair.

scientific article

The role of novel genes rrp1(+) and rrp2(+) in the repair of DNA damage in Schizosaccharomyces pombe

scientific article published on 29 January 2009

The roles of individual polyoma virus early proteins in oncogenic transformation

scientific article published in December 1982

Three novel antibiotic marker cassettes for gene disruption and marker switching in Schizosaccharomyces pombe

scientific article published in October 2005

TopBP1: A BRCT-scaffold protein functioning in multiple cellular pathways

scientific article published on 30 July 2014

Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase

scientific article

Transformation of Schizosaccharomyces pombe: Electroporation Procedure

scientific article published on 01 April 2016

Transformation of Schizosaccharomyces pombe: Lithium Acetate/ Dimethyl Sulfoxide Procedure

scientific article published on 01 April 2016

Transformation of Schizosaccharomyces pombe: Protoplast Procedure

scientific article published on 01 April 2016

U.v.-hypermutability of xeroderma pigmentosum cells demonstrated with a DNA-based mutation system.

scientific article published on May 1995

Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development

scientific article published in May 2000

Vectors for the expression of tagged proteins in Schizosaccharomyces pombe.

scientific article published on October 1998

Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe

scientific article published on May 1, 1992

Virtual-'light-sheet' single-molecule localisation microscopy enables quantitative optical sectioning for super-resolution imaging

scientific article

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