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List of works by Robert J. Geraghty

4,7-Disubstituted 7H-Pyrrolo[2,3-d]pyrimidines and Their Analogs as Antiviral Agents against Zika Virus

scientific article published in 2021

5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus

scientific article published on 4 May 2015

A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and pseudorabies virus

scientific article

A fluorescence-based high-throughput assay to identify inhibitors of tyrosylprotein sulfotransferase activity.

scientific article

A virus-binding hot spot on human angiotensin-converting enzyme 2 is critical for binding of two different coronaviruses

scientific article published on 16 March 2011

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus

scientific article published on 7 June 2012

Cell type-dependence for Vpu function

scientific article (publication date: 1994)

Cellular expression of alphaherpesvirus gD interferes with entry of homologous and heterologous alphaherpesviruses by blocking access to a shared gD receptor

scientific article published in March 2000

Contributions of gD receptors and glycosaminoglycan sulfation to cell fusion mediated by herpes simplex virus 1.

scientific article published in April 2001

Design and synthesis of an activity-based protein profiling probe derived from cinnamic hydroxamic acid.

scientific article published on 23 December 2015

Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor

scientific article

FRET-based assay using a three-way junction DNA substrate to identify inhibitors of human cytomegalovirus pUL89 endonuclease activity

scientific article published on 17 October 2018

Fluorescent peptide sensors for tyrosylprotein sulfotransferase activity

scientific article published on 5 June 2014

Fusion activity of lipid-anchored envelope glycoproteins of herpes simplex virus type 1.

scientific article published in June 2004

HIV-1 particle release mediated by Vpu is distinct from that mediated by p6.

scientific article published on October 1996

Herpes Simplex Virus Glycoprotein D Can Bind to Poliovirus Receptor-Related Protein 1 or Herpesvirus Entry Mediator, Two Structurally Unrelated Mediators of Virus Entry ⬇️

scientific article published on September 1, 1998

Herpes simplex virus type 1 glycoprotein L mutants that fail to promote trafficking of glycoprotein H and fail to function in fusion can induce binding of glycoprotein L-dependent anti-glycoprotein H antibodies

scientific article

Herpes simplex virus type 1 mediates fusion through a hemifusion intermediate by sequential activity of glycoproteins D, H, L, and B

scientific article

Hydroxamic acids block replication of hepatitis C virus

scientific article published on 19 December 2014

Hydroxypyridonecarboxylic Acids as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease

scientific article published on 20 July 2018

Inhibition of Human Cytomegalovirus pUL89 Terminase Subunit Blocks Virus Replication and Genome Cleavage

scientific article published on 23 November 2016

Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus

scientific article published on 30 January 2012

Metal-chelating 3-hydroxypyrimidine-2,4-diones inhibit human cytomegalovirus pUL89 endonuclease activity and virus replication.

scientific article published on 6 February 2018

Mutagenic analysis of herpes simplex virus type 1 glycoprotein L reveals the importance of an arginine-rich region for function.

scientific article published on 28 January 2008

Mutations in the amino terminus of herpes simplex virus type 1 gL can reduce cell-cell fusion without affecting gH/gL trafficking.

scientific article published on 23 October 2013

Nucleobases and corresponding nucleosides display potent antiviral activities against dengue virus possibly through viral lethal mutagenesis.

scientific article

One-Pot Synthesis of 1-Hydroxyacridones from para-Quinols and ortho-Methoxycarbonylaryl Isocyanates

scientific article published on 27 February 2020

Structure activity relationship, 6-modified purine riboside analogues to activate hSTING, stimulator of interferon genes

scientific article published on 12 November 2019

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus ⬇️

scientific article published on October 24, 2011

The nectin-1alpha transmembrane domain, but not the cytoplasmic tail, influences cell fusion induced by HSV-1 glycoproteins.

scientific article

Use of chimeric nectin-1(HveC)-related receptors to demonstrate that ability to bind alphaherpesvirus gD is not necessarily sufficient for viral entry

scientific article published on 01 July 2001

Zika Virus Inhibitors Based on a 1,3-Disubstituted 1H-Pyrazolo[3,4-d]pyrimidine-amine Scaffold

scientific article published in 2022

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