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List of works by Sílvia Busquets

A Rat Immobilization Model Based on Cage Volume Reduction: A Physiological Model for Bed Rest?

scientific article published on 29 March 2017

A differential pattern of gene expression in skeletal muscle of tumor-bearing rats reveals dysregulation of excitation–contraction coupling together with additional muscle alterations.

scientific article published in February 2014

A multifactorial anti-cachectic approach for cancer cachexia in a rat model undergoing chemotherapy

scientific article

Activation of UCPs gene expression in skeletal muscle can be independent on both circulating fatty acids and food intake. Involvement of ROS in a model of mouse cancer cachexia.

scientific article published in January 2005

Anti-inflammatory therapies in cancer cachexia

scientific article

Anticachectic effects of formoterol: a drug for potential treatment of muscle wasting.

scientific article

Antiproteolytic effects of plasma from hibernating bears: a new approach for muscle wasting therapy?

scientific article

Apoptosis is present in skeletal muscle of cachectic gastro-intestinal cancer patients.

scientific article published on 3 August 2007

Apoptosis signalling is essential and precedes protein degradation in wasting skeletal muscle during catabolic conditions

scientific article published on 14 February 2008

Are Peroxisome Proliferator-Activated Receptors Involved in Skeletal Muscle Wasting during Experimental Cancer Cachexia? Role of 2-Adrenergic Agonists

scientific article published on 01 July 2007

Are there any benefits of exercise training in cancer cachexia?

scientific article published on 8 May 2012

Autophagy Exacerbates Muscle Wasting in Cancer Cachexia and Impairs Mitochondrial Function

scientific article published on 28 May 2019

BARD1 content correlates with increased DNA fragmentation associated with muscle wasting in tumour-bearing rats

scientific article published on 01 June 2006

Both oxidative and nitrosative stress are associated with muscle wasting in tumour-bearing rats

scientific article

Branched-chain amino acids inhibit proteolysis in rat skeletal muscle: mechanisms involved.

scientific article

Branched-chain amino acids: a role in skeletal muscle proteolysis in catabolic states?

scientific article

Cachexia and sarcopenia: mechanisms and potential targets for intervention

scientific article published on 11 May 2015

Cachexia: a problem of energetic inefficiency.

scientific article published on 15 August 2014

Calpain-3 gene expression is decreased during experimental cancer cachexia

article

Cancer Cachexia

Cancer cachexia results in an increase in TNF-alpha receptor gene expression in both skeletal muscle and adipose tissue.

scientific article

Cancer cachexia, a clinical challenge.

scientific article published on 18 March 2019

Cancer cachexia: physical activity and muscle force in tumour-bearing rats

scientific article published on 01 January 2011

Cancer cachexia: the molecular mechanisms

scientific article

Cancer cachexia: understanding the molecular basis.

scientific article published on 09 October 2014

Catabolic mediators as targets for cancer cachexia

scientific article

Central melanin-concentrating hormone influences liver and adipose metabolism via specific hypothalamic nuclei and efferent autonomic/JNK1 pathways

scientific article published on 6 November 2012

Changes in mitochondrial electron partitioning in response to herbicides inhibiting branched-chain amino acid biosynthesis in soybean.

scientific article published on 23 October 2003

Combination of exercise training and erythropoietin prevents cancer-induced muscle alterations

scientific article published on 30 November 2015

Combined approach to counteract experimental cancer cachexia: eicosapentaenoic acid and training exercise

scientific article

Complete reversal of muscle wasting in experimental cancer cachexia: Additive effects of activin type II receptor inhibition and β-2 agonist

scientific article published on 23 November 2015

Counteracting inflammation: a promising therapy in cachexia.

scientific article published on January 2012

Cross-talk between skeletal muscle and adipose tissue: a link with obesity?

scientific article published in January 2005

Curcumin, a natural product present in turmeric, decreases tumor growth but does not behave as an anticachectic compound in a rat model

scientific article published in June 2001

Cytokines as mediators and targets for cancer cachexia.

scientific article

DNA Fragmentation Occurs in Skeletal Muscle during Tumor Growth: A Link with Cancer Cachexia?

scientific article published on 01 April 2000

Differences in food intake of tumour-bearing cachectic mice are associated with hypothalamic serotonin signalling

scientific article

Different cytokines modulate ubiquitin gene expression in rat skeletal muscle

article

Differential structural features in soleus and gastrocnemius of carnitine-treated cancer cachectic rats

scientific article published on 26 June 2019

Direct effects of tumor necrosis factor alpha (TNF-alpha) on murine skeletal muscle cell lines. Bimodal effects on protein metabolism

scientific article published on 01 July 2001

Distinct behaviour of sorafenib in experimental cachexia-inducing tumours: the role of STAT3

scientific article

Editorial: Biological Mechanism-Based and Patient-Centered Management of Cancer-Related Symptoms and Syndromes

scientific article published on 18 December 2018

Effect of c-ski overexpression on the development of cachexia in mice bearing the Lewis lung carcinoma.

scientific article

Effects of CRF2R agonist on tumor growth and cachexia in mice implanted with Lewis lung carcinoma cells.

scientific article published on February 2008

Effects of Eicosapentaenoic Acid (EPA) Treatment on Insulin Sensitivity in an Animal Model of Diabetes: Improvement of the Inflammatory Status

scientific article published on 30 September 2010

Effects of IL-15 on rat brown adipose tissue: uncoupling proteins and PPARs

scientific journal article

Effects of formoterol on protein metabolism in myotubes during hyperthermia.

scientific article published on February 2011

Effects of interleukin-15 (IL-15) on adipose tissue mass in rodent obesity models: evidence for direct IL-15 action on adipose tissue

scientific article

Effects of interleukin-15 on lipid oxidation: disposal of an oral [(14)C]-triolein load

scientific article published on 18 January 2006

Effects of the PPARgamma agonist GW1929 on muscle wasting in tumour-bearing mice.

scientific article

Effects of the beta2 agonist formoterol on atrophy signaling, autophagy, and muscle phenotype in respiratory and limb muscles of rats with cancer-induced cachexia

scientific article published on 12 April 2018

Effects of water stress on respiration in soybean leaves

scientific article published on 26 August 2005

Emerging drugs for cancer cachexia.

scientific article published on November 2007

Exercise Reduces the Resumption of Tumor Growth and Proteolytic Pathways in the Skeletal Muscle of Mice Following Chemotherapy

scientific article published on 20 November 2020

Experimental cancer cachexia: Evolving strategies for getting closer to the human scenario

scientific article published on 03 September 2015

Formoterol and cancer muscle wasting in rats: Effects on muscle force and total physical activity.

scientific article published on 28 April 2011

Formoterol attenuates increased oxidative stress and myosin protein loss in respiratory and limb muscles of cancer cachectic rats.

scientific article published on 13 December 2017

Formoterol in the treatment of experimental cancer cachexia: effects on heart function

scientific article published on 29 August 2014

Formoterol treatment downregulates the myostatin system in skeletal muscle of cachectic tumour-bearing rats

scientific article published on 13 October 2011

Hyperlipemia: a role in regulating UCP3 gene expression in skeletal muscle during cancer cachexia?

scientific article published in September 2001

IGF-1 is downregulated in experimental cancer cachexia

scientific article published on 13 April 2006

Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells.

scientific article

Impaired voltage-gated K+ channel expression in brain during experimental cancer cachexia.

scientific article published in February 2003

In the rat, tumor necrosis factor α administration results in an increase in both UCP2 and UCP3 mRNAs in skeletal muscle: a possible mechanism for cytokine-induced thermogenesis?

scientific article published on 01 December 1998

Increased muscle ubiquitin mRNA levels in gastric cancer patients

scientific article published on 01 May 2001

Increased uncoupling protein-2 gene expression in brain of lipopolysaccharide-injected mice: role of tumour necrosis factor-alpha?

scientific article published on January 2001

Inflammation in Cachexia.

scientific article published on 7 October 2015

Inter-tissue communication in cancer cachexia

scientific article published on 01 December 2018

Interleukin-15 affects differentiation and apoptosis in adipocytes: implications in obesity.

scientific article

Interleukin-15 decreases lipid intestinal absorption

scientific article published in June 2005

Interleukin-15 decreases proteolysis in skeletal muscle: a direct effect.

scientific article

Interleukin-15 increases glucose uptake in skeletal muscle. An antidiabetogenic effect of the cytokine.

scientific article published on 12 September 2006

Interleukin-15 is able to suppress the increased DNA fragmentation associated with muscle wasting in tumour-bearing rats

scientific article published in July 2004

Interleukin-15 mediates reciprocal regulation of adipose and muscle mass: a potential role in body weight control

scientific article published in April 2001

Lack of effect of the cytokine suppressive agent FR167653 on tumour growth and cachexia in rats bearing the Yoshida AH-130 ascites hepatoma

scientific article published on 01 August 2000

Mechanism for the increased skeletal muscle protein degradation in the obese zucker rat

scientific article published on 01 April 1999

Mechanisms and treatment of cancer cachexia.

scientific article published on 30 June 2012

Mechanisms to explain wasting of muscle and fat in cancer cachexia

scientific article

Mediators involved in the cancer anorexia-cachexia syndrome: past, present, and future.

scientific article

Mediators of cachexia in cancer patients

scientific article published on 29 March 2019

Megestrol acetate treatment influences tissue amino acid uptake and incorporation during cancer cachexia

Megestrol acetate: its impact on muscle protein metabolism supports its use in cancer cachexia

scientific article published on December 2010

Metabolic interrelationships between liver and skeletal muscle in pathological states.

scientific article

Mitochondrial and sarcoplasmic reticulum abnormalities in cancer cachexia: altered energetic efficiency?

scientific article

Modulations of the calcineurin/NF-AT pathway in skeletal muscle atrophy.

scientific article published on 16 March 2007

Molecular mechanisms involved in muscle wasting in cancer and ageing: cachexia versus sarcopenia

scientific article

Muscle Wasting in Cancer and Ageing: Cachexia Versus Sarcopenia

Muscle ubiquitin m-rNA levels in patients with end-stage renal disease on maintenance hemodialysis

scientific article published on 01 September 2002

Muscle wasting in cancer: the role of mitochondria.

scientific article published on May 2015

Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance.

scientific article published on 8 November 2011

Nonmuscle Tissues Contribution to Cancer Cachexia

scientific article

Novel approaches to the treatment of cachexia.

scientific article

Novel targeted therapies for cancer cachexia.

scientific article

Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia

scientific article

Nutraceutical inhibition of muscle proteolysis: A role of diallyl sulphide in the treatment of muscle wasting

scientific article published on 22 July 2010

Optimal management of cancer anorexia-cachexia syndrome.

scientific article

Overexpression of UCP3 in both murine and human myotubes is linked with the activation of proteolytic systems: A role in muscle wasting?

scientific article published on 15 November 2005

PPARdelta mediates IL15 metabolic actions in myotubes: effects of hyperthermia.

scientific article

Patterns of gene expression in muscle and fat in tumor-bearing rats: effects of CRF2R agonist on cachexia.

scientific article

Protein turnover in skeletal muscle of the diabetic rat: activation of ubiquitin-dependent proteolysis

scientific article published on 01 June 1998

Rat liver lipogenesis is modulated by interleukin-15.

scientific article

Redox balance and carbonylated proteins in limb and heart muscles of cachectic rats.

scientific article published in March 2010

Reduced protein degradation rates and low expression of proteolytic systems support skeletal muscle hypertrophy in transgenic mice overexpressing the c-ski oncogene

scientific article published on 01 October 2003

Resveratrol does not ameliorate muscle wasting in different types of cancer cachexia models

scientific article published on 29 January 2007

Resveratrol, a natural diphenol, reduces metastatic growth in an experimental cancer model.

scientific article published on 7 February 2006

Sepsis induces DNA fragmentation in rat skeletal muscle

scientific article published on 01 October 2003

Short-term effects of leptin on skeletal muscle protein metabolism in the rat

scientific article published on 01 September 2000

Sirtuin 1 in skeletal muscle of cachectic tumour-bearing rats: a role in impaired regeneration?

scientific article

Skeletal muscle UCP2 and UCP3 gene expression in a rat cancer cachexia model

article

Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model

article

Systemic inflammation correlates with increased expression of skeletal muscle ubiquitin but not uncoupling proteins in cancer cachexia.

scientific article published in July 2005

TNF-alpha is involved in activating DNA fragmentation in skeletal muscle

scientific article published on March 2002

TNF-alpha modulates cytokine and cytokine receptors in C2C12 myotubes

scientific article

Targets in clinical oncology: the metabolic environment of the patient.

scientific article published on May 2007

The AP-1/CJUN signaling cascade is involved in muscle differentiation: implications in muscle wasting during cancer cachexia.

scientific article published on 5 January 2006

The AP-1/NF-kappaB double inhibitor SP100030 can revert muscle wasting during experimental cancer cachexia

scientific article published on 01 May 2007

The Increased Skeletal Muscle Protein Turnover of the Streptozotozin Diabetic Rat Is Associated with High Concentrations of Branched-Chain Amino Acids

scientific article published on 01 June 1997

The animal cachexia score (ACASCO)

scientific article published on 16 September 2019

The cachexia score (CASCO): a new tool for staging cachectic cancer patients.

scientific article

The divergent effects of tumour necrosis factor-alpha on skeletal muscle: implications in wasting.

scientific article

The pharmacological treatment of cachexia.

scientific article published on April 2004

The pivotal role of cytokines in muscle wasting during cancer

scientific article published on 01 October 2005

The pivotal role of cytokines in muscle wasting during cancer.

scientific article

The role of cytokines in cancer cachexia

scientific article published on 01 December 2009

The role of uncoupling proteins in pathophysiological states

scientific article

The systemic inflammatory response is involved in the regulation of K+channel expression in brain via TNF-α-dependent and -independent pathways

scientific article published on 01 August 2004

Theophylline is able to partially revert cachexia in tumour-bearing rats.

scientific article published on 21 August 2012

Therapeutic potential of interleukin-15: a myokine involved in muscle wasting and adiposity

scientific article published on 16 December 2008

Therapeutic strategies against cancer cachexia

scientific article published on 01 January 2019

Therapeutic strategies in cachexia: Current and future directions

Tumor necrosis factor-alpha exerts interleukin-6-dependent and -independent effects on cultured skeletal muscle cells

scientific article published in January 2002

Tumour necrosis factor-alpha uncouples respiration in isolated rat mitochondria.

scientific article published in April 2003

UCP3 overexpression neutralizes oxidative stress rather than nitrosative stress in mouse myotubes

scientific article

Validation of the CAchexia SCOre (CASCO). Staging Cancer Patients: The Use of miniCASCO as a Simplified Tool.

scientific article published on 17 February 2017

[Pathophysiology of neoplasic cachexia]

scientific article published on 01 May 2006

[Physiology of sarcopenia. Similarities and differences with neoplasic cachexia (muscle impairments in cancer and ageing)].

scientific article published on 01 May 2006

l-Carnitine: An adequate supplement for a multi-targeted anti-wasting therapy in cancer

scientific article published on 19 May 2012

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