List of works - María A. Pajares

Activation of partially purified rat liver lipid methyltransferase by phosphorylation

scientific article published in August 1984

Active-site-mutagenesis study of rat liver betaine-homocysteine S-methyltransferase

scientific journal article

Acute liver injury induces nucleocytoplasmic redistribution of hepatic methionine metabolism enzymes.

scientific article

Amoxicillin Haptenation of <i>α</i>-Enolase is Modulated by Active Site Occupancy and Acetylation

scientific article published on 01 January 2021

Analysis of the 5' non-coding region of rat liver S-adenosylmethionine synthetase mRNA and comparison of the Mr deduced from the cDNA sequence and the purified enzyme

scientific article published in September 1991

Assignment of a single disulfide bridge in rat liver methionine adenosyltransferase

scientific article published in January 2000

Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels

scientific article published on 25 May 2018

Betaine homocysteine S-methyltransferase emerges as a new player of the nuclear methionine cycle

scientific article published on 10 March 2017

Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism?

scientific article

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia

scientific article published on 12 February 2019

Calcium-dependent binding between calmodulin and lysozyme

scientific article published on 10 April 1989

Characterization of rat liver-specific methionine adenosyltransferase gene promoter. Role of distal upstream cis-acting elements in the regulation of the transcriptional activity

scientific article published in September 1997

Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss

scientific article

Conformational signals in the C-terminal domain of methionine adenosyltransferase I/III determine its nucleocytoplasmic distribution

scientific journal article

Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding

scientific article

Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism

scientific article

Crystallization and preliminary X-ray study of recombinant betaine-homocysteine S-methyltransferase from rat liver.

scientific article published on 23 August 2002

Cu2+ binding triggers αBoPrP assembly into insoluble laminar polymers

scientific article published on 01 January 2004

Cyclopentenone prostaglandins with dienone structure promote cross-linking of the chemoresistance-inducing enzyme glutathione transferase P1-1.

scientific article published on 14 July 2010

Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase

scientific article published on 4 August 2016

Differential expression pattern of S-adenosylmethionine synthetase isoenzymes during rat liver development.

scientific article published in October 1996

Early effects of copper accumulation on methionine metabolism

scientific article published in July 2008

Equilibrium unfolding studies of the rat liver methionine adenosyltransferase III, a dimeric enzyme with intersubunit active sites

scientific article

Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism

scientific article

Glucocorticoid regulation of hepatic S-adenosylmethionine synthetase gene expression

scientific article published on 01 March 1997

How are mammalian methionine adenosyltransferases regulated in the liver? A focus on redox stress

scientific article published on 11 May 2013

How is rat liver S-adenosylmethionine synthetase regulated?

scientific article published on August 1992

Identification of hepatic protein-protein interaction targets for betaine homocysteine S-methyltransferase.

scientific article published on 20 June 2018

Inactivation and dissociation of S-adenosylmethionine synthetase by modification of sulfhydryl groups and its possible occurrence in cirrhosis

scientific article published on 01 February 1990

Integrated approaches to unravel the impact of protein lipoxidation on macromolecular interactions

scientific article published on 13 April 2019

Interplay between Nutrition and Hearing Loss: State of Art

scientific article published on 24 December 2018

Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme.

scientific article

Long-Term Dietary Folate Deficiency Accelerates Progressive Hearing Loss on CBA/Ca Mice.

scientific article published on 31 August 2016

Long-term omega-3 fatty acid supplementation prevents expression changes in cochlear homocysteine metabolism and ameliorates progressive hearing loss in C57BL/6J mice

scientific article published on 31 July 2015

Mammalian Sulfur Amino Acid Metabolism: A Nexus Between Redox Regulation, Nutrition, Epigenetics, and Detoxification

scientific article published on 30 November 2017

Methionine Adenosyltransferase as a Useful Molecular Systematics Tool Revealed by Phylogenetic and Structural Analyses

scientific article published on 01 January 2004

Modulation by the ratio S-adenosylmethionineS-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase

scientific article published in December 1985

NADP+ binding to the regulatory subunit of methionine adenosyltransferase II increases intersubunit binding affinity in the hetero-trimer.

scientific article

PDRG1 at the interface between intermediary metabolism and oncogenesis

scientific article published in November 2017

Prion Protein Interaction with Glycosaminoglycan Occurs with the Formation of Oligomeric Complexes Stabilized by Cu(II) Bridges

scientific article published on 01 May 2002

Rat liver betaine-homocysteine S-methyltransferase equilibrium unfolding: insights into intermediate structure through tryptophan substitutions.

scientific article

Recombinant rat liver S-adenosyl-L-methionine synthetase tetramers and dimers are in equilibrium

scientific journal article

Refolding and Characterization of Rat Liver Methionine Adenosyltransferase from Escherichia coli Inclusion Bodies

scientific article published on 01 July 2000

Refolding and characterization of methionine adenosyltransferase from Euglena gracilis ⬇️

scientific article published on May 14, 2011

Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

scientific article published on 18 November 1996

S-adenosylmethionine synthesis: molecular mechanisms and clinical implications

scientific journal article

S-adenosylmethionine treatment prevents carbon tetrachloride-induced S-adenosylmethionine synthetase inactivation and attenuates liver injury

scientific article published on 01 October 1992

Structural basis for the stability of a thermophilic methionine adenosyltransferase against guanidinium chloride ⬇️

scientific article published on December 4, 2010

Structure-function relationships in methionine adenosyltransferases

scientific article

The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases

scientific article

The crystal structure of tetrameric methionine adenosyltransferase from rat liver reveals the methionine-binding site

scientific article published in July 2000

Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

scientific article published on 08 January 2019

Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division

scientific article published on 13 September 2019

List of works by María A. Pajares

Activation of partially purified rat liver lipid methyltransferase by phosphorylation

Active-site-mutagenesis study of rat liver betaine-homocysteine S-methyltransferase

Acute liver injury induces nucleocytoplasmic redistribution of hepatic methionine metabolism enzymes.

Amoxicillin Haptenation of <i>α</i>-Enolase is Modulated by Active Site Occupancy and Acetylation

Analysis of the 5' non-coding region of rat liver S-adenosylmethionine synthetase mRNA and comparison of the Mr deduced from the cDNA sequence and the purified enzyme

Assignment of a single disulfide bridge in rat liver methionine adenosyltransferase

Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels

Betaine homocysteine S-methyltransferase emerges as a new player of the nuclear methionine cycle

Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism?

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia

Calcium-dependent binding between calmodulin and lysozyme

Characterization of rat liver-specific methionine adenosyltransferase gene promoter. Role of distal upstream cis-acting elements in the regulation of the transcriptional activity

Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss

Conformational signals in the C-terminal domain of methionine adenosyltransferase I/III determine its nucleocytoplasmic distribution

Crystal structure of rat liver betaine homocysteine s-methyltransferase reveals new oligomerization features and conformational changes upon substrate binding

Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism

Crystallization and preliminary X-ray study of recombinant betaine-homocysteine S-methyltransferase from rat liver.

Cu2+ binding triggers αBoPrP assembly into insoluble laminar polymers

Cyclopentenone prostaglandins with dienone structure promote cross-linking of the chemoresistance-inducing enzyme glutathione transferase P1-1.

Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase

Differential expression pattern of S-adenosylmethionine synthetase isoenzymes during rat liver development.

Early effects of copper accumulation on methionine metabolism

Equilibrium unfolding studies of the rat liver methionine adenosyltransferase III, a dimeric enzyme with intersubunit active sites

Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism

Glucocorticoid regulation of hepatic S-adenosylmethionine synthetase gene expression

How are mammalian methionine adenosyltransferases regulated in the liver? A focus on redox stress

How is rat liver S-adenosylmethionine synthetase regulated?

Identification of hepatic protein-protein interaction targets for betaine homocysteine S-methyltransferase.

Inactivation and dissociation of S-adenosylmethionine synthetase by modification of sulfhydryl groups and its possible occurrence in cirrhosis

Integrated approaches to unravel the impact of protein lipoxidation on macromolecular interactions

Interplay between Nutrition and Hearing Loss: State of Art

Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme.

Long-Term Dietary Folate Deficiency Accelerates Progressive Hearing Loss on CBA/Ca Mice.

Long-term omega-3 fatty acid supplementation prevents expression changes in cochlear homocysteine metabolism and ameliorates progressive hearing loss in C57BL/6J mice

Mammalian Sulfur Amino Acid Metabolism: A Nexus Between Redox Regulation, Nutrition, Epigenetics, and Detoxification

Methionine Adenosyltransferase as a Useful Molecular Systematics Tool Revealed by Phylogenetic and Structural Analyses

Modulation by the ratio S-adenosylmethionineS-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase

NADP+ binding to the regulatory subunit of methionine adenosyltransferase II increases intersubunit binding affinity in the hetero-trimer.

PDRG1 at the interface between intermediary metabolism and oncogenesis

Prion Protein Interaction with Glycosaminoglycan Occurs with the Formation of Oligomeric Complexes Stabilized by Cu(II) Bridges

Rat liver betaine-homocysteine S-methyltransferase equilibrium unfolding: insights into intermediate structure through tryptophan substitutions.

Recombinant rat liver S-adenosyl-L-methionine synthetase tetramers and dimers are in equilibrium

Refolding and Characterization of Rat Liver Methionine Adenosyltransferase from Escherichia coli Inclusion Bodies

Refolding and characterization of methionine adenosyltransferase from Euglena gracilis ⬇️

Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione

S-adenosylmethionine synthesis: molecular mechanisms and clinical implications

S-adenosylmethionine treatment prevents carbon tetrachloride-induced S-adenosylmethionine synthetase inactivation and attenuates liver injury

Structural basis for the stability of a thermophilic methionine adenosyltransferase against guanidinium chloride ⬇️

Structure-function relationships in methionine adenosyltransferases

The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases

The crystal structure of tetrameric methionine adenosyltransferase from rat liver reveals the methionine-binding site

Vimentin disruption by lipoxidation and electrophiles: Role of the cysteine residue and filament dynamics

Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division