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List of works by Melkam Kebede

A fluorescent timer reporter enables sorting of insulin secretory granules by age

scientific article published on 27 April 2020

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

scientific article published on 06 May 2019

Branched chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control

scientific article published on 29 April 2019

Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets

scientific article published on 31 August 2009

Dual-Reporter β-Cell-Specific Male Transgenic Rats for the Analysis of β-Cell Functional Mass and Enrichment by Flow Cytometry

scientific article published on 15 December 2015

Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis

scientific article published on 23 February 2006

Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function

scientific article published on 28 March 2008

Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1

scientific article

High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice

scientific article published on 13 February 2018

High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction

scientific article published on August 2005

Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.

scientific article published on 6 October 2007

Insights into obesity and diabetes at the intersection of mouse and human genetics

scientific article

Modulation of central leptin sensitivity and energy balance in a rat model of diet-induced obesity

article by Fam BC et al published November 2007 in Diabetes, Obesity and Metabolism

SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells

scientific article

TRAIL-Expressing Monocyte/Macrophages Are Critical for Reducing Inflammation and Atherosclerosis

scientific article published on 04 January 2019

The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets

scientific article

The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.

scientific article published on 16 June 2008

The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets.

scientific article

Type 2 diabetes-associated single nucleotide polymorphism in Sorcs1 gene results in alternative processing of the Sorcs1 protein in INS1 β-cells

scientific article published on 19 December 2019

Zinc, insulin, and the liver: a ménage à trois

scientific article published on 24 September 2013

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