List of works - Filippo Maria Perna

"The Great Beauty" of organolithium chemistry: a land still worth exploring

scientific article published on October 2014

2-Lithiated-2-phenyloxetane: a new attractive synthon for the preparation of oxetane derivatives

scientific article published on 04 August 2011

2-Lithio-3,3-dimethyl-2-oxazolinyloxirane: carbanion or azaenolate? Structure, configurational stability, and stereodynamics in solution

scientific article

An Expeditious and Greener Synthesis of 2-Aminoimidazoles in Deep Eutectic Solvents.

scientific article published on 16 July 2016

An efficient route to tetrahydronaphthols via addition of ortho-lithiated stilbene oxides to alpha,beta-unsaturated fischer carbene Complexes

scientific article published on 01 October 2005

Asymmetric synthesis of cyclopropanes from lithiated aryloxiranes and alpha,beta-unsaturated Fischer carbene complexes

scientific article published in July 2005

Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil-Like Compounds

scientific article published on 28 January 2020

Deep Eutectic Solvents as Novel and Effective Extraction Media for Quantitative Determination of Ochratoxin A in Wheat and Derived Products.

scientific article published on 12 January 2017

Designing Eco-Sustainable Dye-Sensitized Solar Cells by the Use of a Menthol-Based Hydrophobic Eutectic Solvent as an Effective Electrolyte Medium

scientific article published on 30 October 2018

Directed ortho-metalation-nucleophilic acyl substitution strategies in deep eutectic solvents: the organolithium base dictates the chemoselectivity

scientific article published on 06 June 2019

Dynamic resolution of lithiated ortho-trifluoromethyl styrene oxide and the effect of chiral diamines on the barrier to enantiomerisation

scientific article published in May 2013

Exploiting the lithiation-directing ability of oxetane for the regioselective preparation of functionalized 2-aryloxetane scaffolds under mild conditions

scientific article published on 13 June 2012

Gated access to α-lithiated phenyltetrahydrofuran: functionalisation via direct lithiation of the parent oxygen heterocycle

scientific article published on 01 October 2013

Ligand-Free Bioinspired Suzuki-Miyaura Coupling Reactions using Aryltrifluoroborates as Effective Partners in Deep Eutectic Solvents

scientific article published on 05 September 2018

Lithiated fluorinated styrene oxides: configurational stability, synthetic applications, and mechanistic insight

scientific article published on August 2010

Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer's Disease

scientific article published on 29 August 2018

On the dichotomic reactivity of lithiated styrene oxide: a computational and multinuclear magnetic resonance investigation.

scientific article published in August 2009

Organotrifluoroborates as attractive self-assembling systems: the case of bifunctional dipotassium phenylene-1,4-bis(trifluoroborate)

article

Preparation of polysubstituted isochromanes by addition of ortho-lithiated aryloxiranes to enaminones

scientific article published on 24 October 2013

Regiodivergent synthesis of functionalized pyrimidines and imidazoles through phenacyl azides in deep eutectic solvents

scientific article published on 05 August 2020

Regioselective desymmetrization of diaryltetrahydrofurans via directed ortho-lithiation: an unexpected help from green chemistry

scientific article published on 26 June 2014

Resolution of phthalans obtained by ortho-litiathion of aryloxiranes by enantioselective high-performance liquid chromatography: performances of various chiral stationary phases

scientific article published on 23 January 2009

Solvent and TMEDA effects on the configurational stability of chiral lithiated aryloxiranes

scientific article published on 25 May 2011

Stereoselective synthesis of pentacarbonyl(3-oxa-2-bicyclo[3.1.0]hexylidene)- and pentacarbonyl(cyclopropylmethoxymethylene)tungsten compounds on the route to cyclopropane-gamma-lactones and -carboxylates

scientific article published on 01 December 2004

Sustainable chemo-enzymatic preparation of enantiopure (<i>R</i>)-β-hydroxy-1,2,3-triazoles <i>via</i> lactic acid bacteria-mediated bioreduction of aromatic ketones and a heterogeneous “click” cycloaddition reaction in deep eutectic solvents

scientific article published in 2020

Synthesis of 1,3-dihydrobenzo[c]furans from ortho-lithiated aryloxiranes

scientific article published on 01 May 2006

Synthesis of 2,3-dihydro-10bh-oxazolo[2,3-a]isoquinolines from ortho-lithiated phenyloxazolinyloxiranes

scientific article published on 04 July 2007

Synthesis of allylic alcohols from oxazolinyloxiranes

scientific article

Synthetic approach to substituted cyclopropanes based on the coupling reaction of lithiated chloroalkyloxazolines with Fischer carbene complexes

scientific article

Unexpected lateral-lithiation-induced alkylative ring opening of tetrahydrofurans in deep eutectic solvents: synthesis of functionalised primary alcohols

scientific article published on 01 June 2015

Unprecedented Nucleophilic Additions of Highly Polar Organometallic Compounds to Imines and Nitriles Using Water as a Non-Innocent Reaction Medium.

scientific article published on 11 July 2017

Water and Sodium Chloride: Essential Ingredients for Robust and Fast Pd-Catalysed Cross-Coupling Reactions between Organolithium Reagents and (Hetero)aryl Halides

scientific article published on 17 January 2019

Water opens the door to organolithiums and Grignard reagents: exploring and comparing the reactivity of highly polar organometallic compounds in unconventional reaction media towards the synthesis of tetrahydrofurans.

scientific article published on 3 November 2015

List of works by Filippo Maria Perna

"The Great Beauty" of organolithium chemistry: a land still worth exploring

2-Lithiated-2-phenyloxetane: a new attractive synthon for the preparation of oxetane derivatives

2-Lithio-3,3-dimethyl-2-oxazolinyloxirane: carbanion or azaenolate? Structure, configurational stability, and stereodynamics in solution

An Expeditious and Greener Synthesis of 2-Aminoimidazoles in Deep Eutectic Solvents.

An efficient route to tetrahydronaphthols via addition of ortho-lithiated stilbene oxides to alpha,beta-unsaturated fischer carbene Complexes

Asymmetric synthesis of cyclopropanes from lithiated aryloxiranes and alpha,beta-unsaturated Fischer carbene complexes

Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-based Scaffolds en Route to Donepezil-Like Compounds

Deep Eutectic Solvents as Novel and Effective Extraction Media for Quantitative Determination of Ochratoxin A in Wheat and Derived Products.

Designing Eco-Sustainable Dye-Sensitized Solar Cells by the Use of a Menthol-Based Hydrophobic Eutectic Solvent as an Effective Electrolyte Medium

Directed ortho-metalation-nucleophilic acyl substitution strategies in deep eutectic solvents: the organolithium base dictates the chemoselectivity

Dynamic resolution of lithiated ortho-trifluoromethyl styrene oxide and the effect of chiral diamines on the barrier to enantiomerisation

Exploiting the lithiation-directing ability of oxetane for the regioselective preparation of functionalized 2-aryloxetane scaffolds under mild conditions

Gated access to α-lithiated phenyltetrahydrofuran: functionalisation via direct lithiation of the parent oxygen heterocycle

Ligand-Free Bioinspired Suzuki-Miyaura Coupling Reactions using Aryltrifluoroborates as Effective Partners in Deep Eutectic Solvents

Lithiated fluorinated styrene oxides: configurational stability, synthetic applications, and mechanistic insight

Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer's Disease

On the dichotomic reactivity of lithiated styrene oxide: a computational and multinuclear magnetic resonance investigation.

Organotrifluoroborates as attractive self-assembling systems: the case of bifunctional dipotassium phenylene-1,4-bis(trifluoroborate)

Preparation of polysubstituted isochromanes by addition of ortho-lithiated aryloxiranes to enaminones

Regiodivergent synthesis of functionalized pyrimidines and imidazoles through phenacyl azides in deep eutectic solvents

Regioselective desymmetrization of diaryltetrahydrofurans via directed ortho-lithiation: an unexpected help from green chemistry

Resolution of phthalans obtained by ortho-litiathion of aryloxiranes by enantioselective high-performance liquid chromatography: performances of various chiral stationary phases

Solvent and TMEDA effects on the configurational stability of chiral lithiated aryloxiranes

Stereoselective synthesis of pentacarbonyl(3-oxa-2-bicyclo[3.1.0]hexylidene)- and pentacarbonyl(cyclopropylmethoxymethylene)tungsten compounds on the route to cyclopropane-gamma-lactones and -carboxylates

Sustainable chemo-enzymatic preparation of enantiopure (<i>R</i>)-β-hydroxy-1,2,3-triazoles <i>via</i> lactic acid bacteria-mediated bioreduction of aromatic ketones and a heterogeneous “click” cycloaddition reaction in deep eutectic solvents

Synthesis of 1,3-dihydrobenzo[c]furans from ortho-lithiated aryloxiranes

Synthesis of 2,3-dihydro-10bh-oxazolo[2,3-a]isoquinolines from ortho-lithiated phenyloxazolinyloxiranes

Synthesis of allylic alcohols from oxazolinyloxiranes

Synthetic approach to substituted cyclopropanes based on the coupling reaction of lithiated chloroalkyloxazolines with Fischer carbene complexes

Unexpected lateral-lithiation-induced alkylative ring opening of tetrahydrofurans in deep eutectic solvents: synthesis of functionalised primary alcohols

Unprecedented Nucleophilic Additions of Highly Polar Organometallic Compounds to Imines and Nitriles Using Water as a Non-Innocent Reaction Medium.

Water and Sodium Chloride: Essential Ingredients for Robust and Fast Pd-Catalysed Cross-Coupling Reactions between Organolithium Reagents and (Hetero)aryl Halides

Water opens the door to organolithiums and Grignard reagents: exploring and comparing the reactivity of highly polar organometallic compounds in unconventional reaction media towards the synthesis of tetrahydrofurans.