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List of works by Lenore K Beitel

A Targeted Bivalent Androgen Receptor Binding Compound for Prostate Cancer Therapy

scientific article published on 18 December 2018

Altered mRNA expression due to insertion or substitution of thymine at position +3 of two splice-donor sites in the androgen receptor gene

scientific article published in January 1997

An examination of how different mutations at arginine 855 of the androgen receptor result in different androgen insensitivity phenotypes.

scientific article published on 29 April 2004

An investigation into CAG repeat length variation and N/C terminal interactions in the T877A mutant androgen receptor found in prostate cancer.

scientific article

Androgen Insensitivity Syndrome

scientific article published on 11 May 2017

Androgen insensitivity.

scientific article

Androgen receptor CAG repeat length contraction in diseased and non-diseased prostatic tissues

scientific article published on 17 April 2007

Androgen resistance due to mutation of the androgen receptor.

scientific article published on October 1992

Bridging structural biology and genetics by computational methods: an investigation into how the R774C mutation in the AR gene can result in complete androgen insensitivity syndrome

scientific article published in December 2003

Cancer systems biology in the genome sequencing era: part 1, dissecting and modeling of tumor clones and their networks.

scientific article published on 19 June 2013

Cancer systems biology in the genome sequencing era: part 2, evolutionary dynamics of tumor clonal networks and drug resistance.

scientific article published on 18 June 2013

Changing genetic paradigms: creating next-generation genetic databases as tools to understand the emerging complexities of genotype/phenotype relationships

scientific article

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell.

scientific article published on 30 August 2017

Characterization of intracellular aggregates using fluorescently-tagged polyglutamine-expanded androgen receptor

scientific article published in July 2001

Characterization of the NPC1L1 gene and proteome from an exceptional responder to ezetimibe

scientific article published on 24 December 2015

Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.

scientific article

Codon-usage variants in the polymorphic (GGN) n trinucleotide repeat of the human androgen receptor gene ⬇️

scientific article published on November 1, 1997

Complete androgen insensitivity due to mutations in the probable alpha-helical segments of the DNA-binding domain in the human androgen receptor.

scientific article published on January 1994

Cytochrome c oxidase subunit Vb interacts with human androgen receptor: a potential mechanism for neurotoxicity in spinobulbar muscular atrophy

scientific article published in October 2001

Demonstration of a plasmonic thermocycler for the amplification of human androgen receptor DNA.

scientific article

Dynamic rewiring of the androgen receptor protein interaction network correlates with prostate cancer clinical outcomes

scientific article published on 7 September 2011

Estrogen and androgen protection of human neurons against intracellular amyloid beta1-42 toxicity through heat shock protein 70.

scientific article

Handheld impedance biosensor system using engineered proteinaceous receptors

scientific article published on December 2010

Impaired helix 12 dynamics due to proline 892 substitutions in the androgen receptor are associated with complete androgen insensitivity

scientific article published on 31 January 2006

Making sense of intratumor genetic heterogeneity: altered frequency of androgen receptor CAG repeat length variants in breast cancer tissues.

scientific article

Mechanisms mediating spinal and bulbar muscular atrophy: investigations into polyglutamine-expanded androgen receptor function and dysfunction.

scientific article published on 15 May 2013

Molecular pathology of the androgen receptor in male (in)fertility

scientific article

Molecular studies of a patient with complete androgen insensitivity and a 47,XXY karyotype

scientific article published in September 2009

Open Science Meets Stem Cells: A New Drug Discovery Approach for Neurodegenerative Disorders

scientific article published on 6 February 2018

Patient-Derived Stem Cells, Another in vitro Model, or the Missing Link Toward Novel Therapies for Autism Spectrum Disorders?

scientific article published on 06 June 2019

Polymorphisms and HNPCC: PMS2-MLH1 protein interactions diminished by single nucleotide polymorphisms

scientific article

Progress in Spinobulbar muscular atrophy research: insights into neuronal dysfunction caused by the polyglutamine-expanded androgen receptor.

scientific article

Real time plasmonic qPCR: how fast is ultra-fast? 30 cycles in 54 seconds

scientific article published on 26 April 2017

Selection and mutation in the "new" genetics: an emerging hypothesis.

scientific article published on 23 January 2010

Somatic mosaicism and cancer: a micro-genetic examination into the role of the androgen receptor gene in prostate cancer.

scientific article

Somatic mosaicism and variable expressivity

scientific article published on 01 February 2001

Somatic mosaicism of androgen receptor CAG repeats in colorectal carcinoma epithelial cells from men.

scientific article

Structure-guided combination therapy to potently improve the function of mutant CFTRs

article

Substitution of valine-865 by methionine or leucine in the human androgen receptor causes complete or partial androgen insensitivity, respectively with distinct androgen receptor phenotypes.

scientific article

The Androgen Receptor Gene Mutations Database

scientific article published on 01 January 1998

The androgen receptor gene mutations database: 2012 update.

scientific article published on 13 March 2012

The polymorphic CAG repeat of the androgen receptor gene: a potential role in breast cancer in women over 40

article

The use of androgen receptor amino/carboxyl-terminal interaction assays to investigate androgen receptor gene mutations in subjects with varying degrees of androgen insensitivity.

scientific article published on May 2003

Transglutaminase potentiates ligand-dependent proteasome dysfunction induced by polyglutamine-expanded androgen receptor

scientific article

Underexpression of mineralocorticoid receptor in colorectal carcinomas and association with VEGFR-2 overexpression

scientific article published on 17 August 2007

Update of the androgen receptor gene mutations database

scientific article published in January 1999

Will knowledge of human genome variation result in changing cancer paradigms?

scientific article published on July 2007

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