List of works by Andreas Hoeflich

A highly sensitive immunofluorometric assay for the measurement of aldosterone in small sample volumes: validation in mouse serum.

scientific article published in February 2008

A microsphere-based duplex competitive immunoassay for the simultaneous measurements of aldosterone and testosterone in small sample volumes: validation in human and mouse plasma

scientific article published on 21 July 2010

Analysis of Activity-Dependent Energy Metabolism in Mice Reveals Regulation of Mitochondrial Fission and Fusion mRNA by Voluntary Physical Exercise in Subcutaneous Fat from Male Marathon Mice (DUhTP)

scientific article published on 16 December 2020

Analysis of the IGF-system in milk from farm animals - Occurrence, regulation, and biomarker potential

scientific article

Antepartal insulin-like growth factor 1 and insulin-like growth factor binding protein 2 concentrations are indicative of ketosis in dairy cows

scientific article published on 20 February 2015

Bioanalytical validation for simultaneous quantification of non-aromatic steroids in follicular fluid from cattle via ESI-LC–MS/MS

scientific article published on 07 November 2015

Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.

scientific article published in April 2002

Characterization of igf1 and igf2 genes during maraena whitefish (Coregonus maraena) ontogeny and the effect of temperature on embryogenesis and igf expression.

scientific article

Chronic growth hormone excess is associated with increased aldosterone: a study in patients with acromegaly and in growth hormone transgenic mice.

scientific article published on 2 June 2009

Contrasting bone effects of temporary versus permanent IGFBP administration in rodents

scientific article published on 04 March 2008

Control of IGFBP-2 Expression by Steroids and Peptide Hormones in Vertebrates

scientific article published on 07 April 2014

Cortical bone loss in androgen-deficient aged male rats is mainly caused by increased endocortical bone remodeling

scientific article published in May 2008

Decreased p44/42 mitogen-activated protein kinase phosphorylation in gender- or hormone-related but not during age-related adrenal gland growth in mice.

scientific article published on 23 October 2008

Defined carboxy-terminal fragments of insulin-like growth factor (IGF) binding protein-2 exert similar mitogenic activity on cultured rat growth plate chondrocytes as IGF-I.

scientific article

Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse

scientific article published on 03 May 2022

Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice

scientific article

Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD-deficient IGFBP-2 variant in female transgenic mice

scientific article

Does the overexpression of pro-insulin-like growth factor-II in transfected human embryonic kidney fibroblasts increase the secretion of lysosomal enzymes?

scientific article published on August 1995

Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3.

scientific article published on 11 April 2013

Effect of maternal supplementation with essential fatty acids and conjugated linoleic acid on metabolic and endocrine development in neonatal calves

scientific article published in 2021

Effects of parturition and feed restriction on concentrations and distribution of the insulin-like growth factor-binding proteins in plasma and cerebrospinal fluid of dairy cows

scientific article published on 5 March 2014

Extrinsic and intrinsic regulation of DOR/TP53INP2 expression in mice: effects of dietary fat content, tissue type and sex in adipose and muscle tissues

scientific article published on 21 September 2012

Functional consequences of IGFBP excess-lessons from transgenic mice

scientific article

Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity

scientific article

Gender-specific effects on food intake but no inhibition of age-related fat accretion in transgenic mice overexpressing human IGFBP-2 lacking the Cardin-Weintraub sequence motif

scientific article published on 8 February 2015

Genome-wide search for loci controlling serum IGF binding protein levels of mice

scientific article published on 01 April 2001

Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth

scientific article published on March 2004

Growth analysis of the mouse adrenal gland from weaning to adulthood: time- and gender-dependent alterations of cell size and number in the cortical compartment

scientific article

Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.

scientific article published in May 2001

Growth selection in mice reveals conserved and redundant expression patterns of the insulin-like growth factor system

scientific article published in April 2004

Hepatic mRNA expression of acid labile subunit and deiodinase 1 differs between cows selected for high versus low concentrations of insulin-like growth factor 1 in late pregnancy.

scientific article published on 19 April 2013

High-fertility phenotypes: two outbred mouse models exhibit substantially different molecular and physiological strategies warranting improved fertility

scientific article published on 2 March 2014

IGF-II transgenic mice display increased aberrant colon crypt multiplicity and tumor volume after 1,2-dimethylhydrazine treatment

scientific article

IGF-binding protein-4: biochemical characteristics and functional consequences

scientific journal article

IGF-binding protein-5: flexible player in the IGF system and effector on its own

scientific article (publication date: March 2002)

IGF-independent effects of IGFBP-2 on the human breast cancer cell line Hs578T.

scientific article published on August 2006

IGFBP-2 overexpression reduces the appearance of dysplastic aberrant crypt foci and inhibits growth of adenomas in chemically induced colorectal carcinogenesis

scientific article published in May 2009

Identification of transgenic mice by direct PCR analysis of lysates of epithelial cells obtained from the inner surface of the rectum

scientific article published on 01 March 1998

In silico approaches and the role of ontologies in aging research

scientific article

Increased activity of catalase in tumor cells overexpressing IGFBP-2.

scientific article published on November 2003

Increased fat mass, decreased myofiber size, and a shift to glycolytic muscle metabolism in adolescent male transgenic mice overexpressing IGFBP-2.

scientific article published on 25 May 2010

Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos

scientific article published on 19 March 2003

Initial characterization of an outbreed mouse model for male factor (in)fertility

scientific article

Insulin glargine and NPH insulin increase to a similar degree epithelial cell proliferation and aberrant crypt foci formation in colons of diabetic mice

scientific article published on December 2010

Insulin-like growth factor (IGF)-I stimulates cell proliferation and induces IGF binding protein (IGFBP)-3 and IGFBP-5 gene expression in cultured growth plate chondrocytes via distinct signaling pathways

scientific article published on 21 April 2005

Insulin-like growth factor (IGF)-binding protein-4 inhibits colony formation of colorectal cancer cells by IGF-independent mechanisms

scientific article published on March 2004

Insulin-like growth factor binding protein 2 (IGFBP-2) separates hypertrophic and hyperplastic effects of growth hormone (GH)/IGF-I excess on adrenocortical cells in vivo

scientific article

Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone/IGF-I excess in transgenic mice

scientific article published on 20 November 2002

Insulin-like growth factor-binding protein-4 inhibits growth of the thymus in transgenic mice.

scientific article published on April 2004

Insulin-like growth factor-binding protein-5 inhibits growth and induces differentiation of mouse osteosarcoma cells

scientific article published in October 2001

Insulin-like growth factors and IGF-binding proteins in bovine seminal plasma

scientific article published in July 1999

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function

scientific article

Integrative Cluster Analysis of Whole Hearts Reveals Proliferative Cardiomyocytes in Adult Mice

scientific article published on 06 May 2020

Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells.

scientific article published in April 2000

Irisin is elevated in skeletal muscle and serum of mice immediately after acute exercise

scientific article published on 11 March 2014

Lack of Dietary Carbohydrates Induces Hepatic Growth Hormone (GH) Resistance in Rats

Lifelong obesity in a polygenic mouse model prevents age- and diet-induced glucose intolerance- obesity is no road to late-onset diabetes in mice

scientific article

Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle?

scientific article published on 31 January 2014

Mechanisms of adrenal gland growth: signal integration by extracellular signal regulated kinases1/2.

scientific article

Metabolic adaptations in the liver of born long-distance running mice

scientific article published in May 2013

Molecular biological fingerprinting of human lectin expression by RT-PCR.

scientific article

Molecular, physiological, and motor performance defects in DMSXL mice carrying >1,000 CTG repeats from the human DM1 locus

scientific article

Mutation of the RGD sequence does not affect plasma membrane association and growth inhibitory effects of elevated IGFBP-2 in vivo

scientific article published in July 2002

Opposite regulation of IGF-I and IGF-I receptor mRNA and concomitant changes of GH receptor and IGF-II/M6P receptor mRNA in human IM-9 lymphoblasts

scientific article published on February 1996

Overlap of Peak Growth Activity and Peak IGF-1 to IGFBP Ratio: Delayed Increase of IGFBPs versus IGF-1 in Serum as a Mechanism to Speed up and down Postnatal Weight Gain in Mice

scientific article published on 22 June 2020

PAPPA2, an enzyme that cleaves an insulin-like growth-factor-binding protein, is a candidate gene for a quantitative trait locus affecting body size in mice

scientific article

Peri/nuclear localization of intact insulin-like growth factor binding protein-2 and a distinct carboxyl-terminal IGFBP-2 fragment in vivo

scientific article published in November 2004

Perturbation of C6 glial cells by acetate leads to modulation of [125I]IGF-II binding to the IGF-II/M6P receptor: implications for ligand internalization studies

scientific article published on 01 September 1994

Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice

scientific article (publication date: 2012)

Physiology and pathophysiology of IGFBP-1 and IGFBP-2 - consensus and dissent on metabolic control and malignant potential

scientific article

Polyethylene glycol-coupled IGF1 delays motor function defects in a mouse model of spinal muscular atrophy with respiratory distress type 1.

scientific article

Postnatally elevated levels of insulin-like growth factor (IGF)-II fail to rescue the dwarfism of IGF-I-deficient mice except kidney weight

scientific article published on 28 September 2006

Pre-B-cell transcription factor 1 and steroidogenic factor 1 synergistically regulate adrenocortical growth and steroidogenesis

scientific article published on 2 November 2006

Quantitative Western ligand blotting reveals common patterns and differential features of IGFBP-fingerprints in domestic ruminant breeds and species

scientific article published on 10 November 2015

Role of the insulin-like growth factor system in adrenocortical growth control and carcinogenesis.

scientific article published in June 2004

Separation of fast from slow anabolism by site-specific PEGylation of insulin-like growth factor I (IGF-I).

scientific article

Serum IGF-I Is Not a Reliable Pharmacodynamic Marker of Exogenous Growth Hormone Activity in Mice

Serum IGFBP4 concentration decreased in dairy heifers towards day 18 of pregnancy

scientific article

Sex-Specific Control of Muscle Mass: Elevated IGFBP Proteolysis and Reductions of IGF-1 Levels Are Associated with Substantial Loss of Carcass Weight in Male DU6PxIGFBP-2 Transgenic Mice

scientific article published on 26 September 2020

Short-term exposure to low-carbohydrate, high-fat diets induces low bone mineral density and reduces bone formation in rats.

scientific article

Systems Biology and Bioinformatics in Aging Research: A Workshop Report

The RGD sequence present in IGFBP-2 is required for reduced glucose clearance after oral glucose administration in female transgenic mice

scientific article published on 23 June 2015

The insulin-like growth factor-II/mannose-6-phosphate receptor is present in fetal bovine tissues throughout gestation.

scientific article published in October 1995

Therapeutic potential of PEGylated insulin-like growth factor I for skeletal muscle disease evaluated in two murine models of muscular dystrophy

scientific article published on 15 March 2012

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation

scientific article published on 7 April 2004

Tumor galectinology: insights into the complex network of a family of endogenous lectins

scientific article published on January 2004

Validation of serum IGF-I as a biomarker to monitor the bioactivity of exogenous growth hormone agonists and antagonists in rabbits

scientific article

Xenogeneic and Stem Cell-Based Therapy for Cardiovascular Diseases: Genetic Engineering of Porcine Cells and Their Applications in Heart Regeneration

scientific article published on 18 December 2020

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