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List of works by Takuya Terai

A Gd3+-based magnetic resonance imaging contrast agent sensitive to beta-galactosidase activity utilizing a receptor-induced magnetization enhancement (RIME) phenomenon.

scientific article

A Time‐Resolved Fluorescence Probe for Dipeptidyl Peptidase 4 and Its Application in Inhibitor Screening

scientific article published on December 3, 2010

A design strategy for small molecule-based targeted MRI contrast agents: their application for detection of atherosclerotic plaques

scientific article published in November 2014

A long-lived luminescent probe to sensitively detect arylamine N-acetyltransferase (NAT) activity of cells.

scientific article published on 17 January 2012

A practical strategy to create near-infrared luminescent probes: conversion from fluorescein-based sensors

scientific article published on 6 January 2012

A reversible near-infrared fluorescence probe for reactive oxygen species based on Te-rhodamine

scientific article published on 17 February 2012

A simple and effective strategy to increase the sensitivity of fluorescence probes in living cells.

scientific article published in July 2009

Aminoluciferins as Functional Bioluminogenic Substrates of Firefly Luciferase

scientific article published on 17 March 2011

Analysis of chemical equilibrium of silicon-substituted fluorescein and its application to develop a scaffold for red fluorescent probes.

scientific article published on 3 August 2015

Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport

scientific article

Boron dipyrromethene as a fluorescent caging group for single-photon uncaging with long-wavelength visible light.

scientific article published on 27 August 2014

Design and development of enzymatically activatable photosensitizer based on unique characteristics of thiazole orange

scientific article

Design and synthesis of a highly sensitive off-on fluorescent chemosensor for zinc ions utilizing internal charge transfer

scientific article published in January 2010

Design and synthesis of a novel fluorescence probe for Zn2+ based on the spirolactam ring-opening process of rhodamine derivatives

scientific article published on 09 June 2010

Design strategy for a near-infrared fluorescence probe for matrix metalloproteinase utilizing highly cell permeable boron dipyrromethene.

scientific article

Detection of NAD(P)H-dependent enzyme activity by time-domain ratiometry of terbium luminescence.

scientific article published on 11 March 2016

Detection of NAD(P)H-dependent enzyme activity with dynamic luminescence quenching of terbium complexes

scientific article published on 01 May 2015

Development of 2,6-carboxy-substituted boron dipyrromethene (BODIPY) as a novel scaffold of ratiometric fluorescent probes for live cell imaging

scientific article published on 08 October 2009

Development of Chemical Tools to Monitor and Control Isoaspartyl Peptide Methyltransferase Activity.

scientific article

Development of NIR fluorescent dyes based on Si-rhodamine for in vivo imaging

scientific article published on 07 March 2012

Development of a Sensitive Bioluminogenic Probe for Imaging Highly Reactive Oxygen Species in Living Rats

scientific article published on 16 October 2015

Development of a Series of Practical Fluorescent Chemical Tools To Measure pH Values in Living Samples

scientific article published on 24 April 2018

Development of a far-red to near-infrared fluorescence probe for calcium ion and its application to multicolor neuronal imaging

scientific article published on 18 August 2011

Development of a fluorescein analogue, TokyoMagenta, as a novel scaffold for fluorescence probes in red region

scientific article published on 28 February 2011

Development of a highly selective fluorescence probe for alkaline phosphatase

scientific article published on 23 March 2011

Development of a highly selective fluorescence probe for hydrogen sulfide

scientific article published on 25 October 2011

Development of a highly sensitive fluorescence probe for hydrogen peroxide.

scientific article published on 21 June 2011

Development of a novel fluorescent probe for fluorescence correlation spectroscopic detection of kinase inhibitors

scientific article published on 16 May 2008

Development of a potassium ion-selective fluorescent sensor based on 3-styrylated BODIPY.

scientific article published on 19 August 2011

Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application.

scientific article published on 3 January 2017

Development of a series of near-infrared dark quenchers based on Si-rhodamines and their application to fluorescent probes.

scientific article

Development of an Azo-Based Photosensitizer Activated under Mild Hypoxia for Photodynamic Therapy

scientific article published on 5 September 2017

Development of an Azoreductase-based Reporter System with Synthetic Fluorogenic Substrates.

scientific article

Development of an Si-rhodamine-based far-red to near-infrared fluorescence probe selective for hypochlorous acid and its applications for biological imaging

scientific article published on 28 March 2011

Development of azo-based fluorescent probes to detect different levels of hypoxia.

scientific article published on 14 October 2013

Development of hypoxia-sensitive Gd3+-based MRI contrast agents

scientific article published on 03 March 2012

Development of luciferin analogues bearing an amino group and their application as BRET donors

scientific article published on September 2010

Development of practical red fluorescent probe for cytoplasmic calcium ions with greatly improved cell-membrane permeability.

scientific article published on 8 June 2016

Diced electrophoresis gel assay for screening enzymes with specified activities

scientific article published on 16 April 2013

Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide

scientific article (publication date: 12 January 2017)

Discovery of Cell-Type-Specific and Disease-Related Enzymatic Activity Changes via Global Evaluation of Peptide Metabolism.

scientific article published on 13 February 2017

Discovery of a pyruvylated peptide-metabolizing enzyme using a fluorescent substrate-based protein discovery technique

scientific article published on 01 March 2016

Evolution of group 14 rhodamines as platforms for near-infrared fluorescence probes utilizing photoinduced electron transfer

scientific article published on 17 March 2011

Fluorescence probe for lysophospholipase C/NPP6 activity and a potent NPP6 inhibitor

scientific article

Fluorometric assay of integrin activity with a small-molecular probe that senses the binding site microenvironment

scientific article published on 01 December 2014

Gliotoxin suppresses NF-κB activation by selectively inhibiting linear ubiquitin chain assembly complex (LUBAC).

scientific article published on 17 December 2014

Highly activatable and environment-insensitive optical highlighters for selective spatiotemporal imaging of target proteins.

scientific article

Hypoxia-sensitive fluorescent probes for in vivo real-time fluorescence imaging of acute ischemia

scientific article published on October 27, 2010

Identification of Lung Inflammation-Related Elevation of Acylamino Acid Releasing Enzyme (APEH) Activity Using an Enzymomics Approach.

scientific article

Identification of tissue-restricted bioreaction suitable for in vivo targeting by fluorescent substrate library-based enzyme discovery.

scientific article published on 11 September 2015

Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells

scientific article

In Vitro Construction of Large-scale DNA Libraries from Fragments Containing Random Regions using Deoxyinosine-containing Oligonucleotides and Endonuclease V

scientific article published on 26 March 2020

In situ evaluation of kinetic resolution catalysts for nitroaldol by rationally designed fluorescence probe

scientific article published on 03 March 2011

In vitro selection of random peptides against artificial lipid bilayers: a potential tool to immobilize molecules on membranes.

scientific article

Modulation of luminescence intensity of lanthanide complexes by photoinduced electron transfer and its application to a long-lived protease probe.

scientific article

Molecular design strategies for near-infrared ratiometric fluorescent probes based on the unique spectral properties of aminocyanines

scientific article published on 01 September 2009

Near-infrared fluorescence probes for enzymes based on binding affinity modulation of squarylium dye scaffold

scientific article published on 30 April 2012

New class of bioluminogenic probe based on bioluminescent enzyme-induced electron transfer: BioLeT.

scientific article published on 19 March 2015

Photocrosslinking of cDNA Display Molecules with Their Target Proteins as a New Strategy for Peptide Selection

scientific article published on 24 March 2020

Practical fluorescence detection of acrolein in human plasma via a two-step tethering approach.

scientific article published in December 2014

Protein-Coupled Fluorescent Probe To Visualize Potassium Ion Transition on Cellular Membranes.

scientific article published on 19 February 2016

Rapidly rendering cells phagocytic through a cell surface display technique and concurrent Rac activation

scientific article

Rational design of boron dipyrromethene (BODIPY)-based photobleaching-resistant fluorophores applicable to a protein dynamics study

scientific article published on August 5, 2011

Rational design of highly sensitive fluorescence probes for protease and glycosidase based on precisely controlled spirocyclization.

scientific article published on 26 December 2012

Rational design of ratiometric near-infrared fluorescent pH probes with various pKa values, based on aminocyanine

scientific article published on 22 February 2011

Rational development of caged-biotin protein-labeling agents and some applications in live cells

scientific article

Red Fluorescent Probe for Monitoring the Dynamics of Cytoplasmic Calcium Ions

scientific article published on February 25, 2013

Red fluorescent scaffold for highly sensitive protease activity probes

scientific article published on 2 May 2012

Reversible Off–On Fluorescence Probe for Hypoxia and Imaging of Hypoxia–Normoxia Cycles in Live Cells

scientific article published on November 26, 2012

Salicylic-acid derivatives as antennae for ratiometric luminescent probes based on lanthanide complexes

scientific article published on 09 May 2012

Selective ablation of β-galactosidase-expressing cells with a rationally designed activatable photosensitizer.

scientific article

Selective two-step labeling of proteins with an off/on fluorescent probe

scientific article published on 22 November 2011

Sensitive detection of acrolein in serum using time-resolved luminescence

scientific article published in April 2010

Site-specific oxidative stress induction

scientific article published on 01 August 2007

Small-molecule fluorophores and fluorescent probes for bioimaging.

scientific article published on 15 February 2013

Synthesis of unsymmetrical Si-rhodamine fluorophores and application to a far-red to near-infrared fluorescence probe for hypoxia

scientific article published on 01 June 2018

Thermal or mechanical stimuli-induced photoluminescence color change of a molecular assembly composed of an amphiphilic anthracene derivative in water

scientific article published on 9 July 2014

TokyoGreen derivatives as specific and practical fluorescent probes for UDP-glucuronosyltransferase (UGT) 1A1

scientific article published on 21 January 2013

Unexpected Photo-instability of 2,6-Sulfonamide-Substituted BODIPYs and Its Application to Caged GABA.

scientific article published on 2 April 2016