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List of works by Haruhiko Kamada

A novel method for construction of gene fragment library to searching epitopes

scientific article

Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice.

scientific article

Acute phase proteins as biomarkers for predicting the exposure and toxicity of nanomaterials

scientific article published on 22 September 2010

Amino acids and peptides. XXXIII. A bifunctional poly(ethylene glycol) hybrid of laminin-related peptides

scientific article

Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes.

scientific article

Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure

scientific article published on 04 January 2012

Amorphous silica nanoparticles enhance cross-presentation in murine dendritic cells

scientific article published on 26 September 2012

An in vitro method for screening anti-platelet agents using a microchannel array flow analyzer

scientific article published on January 2010

Annexin A4 is a possible biomarker for cisplatin susceptibility of malignant mesothelioma cells

scientific article published on April 4, 2012

Anti-inflammatory effects of a novel TNFR1-selective antagonistic TNF mutant on established murine collagen-induced arthritis

scientific article published on 01 January 2011

Application of bioactive mutant TNF alpha to a mucosal vaccine adjuvant

scientific article

Arsenic trioxide inhibits human t cell-lymphotropic virus-1-induced syncytiums by down-regulating gp46.

scientific article published in July 2009

Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist

scientific article

Creation of novel cell-penetrating peptides for intracellular drug delivery using systematic phage display technology originated from Tat transduction domain

scientific article

Design of a pH-sensitive polymeric carrier for drug release and its application in cancer therapy.

scientific article published on April 2004

Development of an antibody proteomics system using a phage antibody library for efficient screening of biomarker proteins

scientific article published on October 8, 2010

Distribution and histologic effects of intravenously administered amorphous nanosilica particles in the testes of mice

scientific article published on 06 March 2012

Effect of amorphous silica nanoparticles on in vitro RANKL-induced osteoclast differentiation in murine macrophages.

scientific article published on 22 July 2011

Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages.

scientific article published on 18 January 2011

Effective accumulation of poly(vinylpyrrolidone-co-vinyl laurate) into the spleen

scientific article published on 01 August 2004

Expression of Eph receptor A10 is correlated with lymph node metastasis and stage progression in breast cancer patients.

scientific article

Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists

scientific article

Fine tuning of receptor-selectivity for tumor necrosis factor-α using a phage display system with one-step competitive panning.

scientific article

Generation and characterization of a bispecific diabody targeting both EPH receptor A10 and CD3.

scientific article published on 17 December 2014

Generation of mouse macrophages expressing membrane-bound TNF variants with selectivity for TNFR1 or TNFR2.

scientific article

Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles

scientific article published on 8 October 2012

Identification of new candidates as mucosal vaccine adjuvant in TNF family cytokines

scientific article published on 01 January 2011

Improved protein sequence coverage by on resin deglycosylation and cysteine modification for biomarker discovery

scientific article

In vitro evaluation of blood coagulation activation and microthrombus formation by a microchannel array flow analyzer

scientific article published on 01 January 2004

In vitro remodeling of tumor vascular endothelial cells using conditioned medium from various tumor cells and their sensitivity to TNF-alpha

scientific article published on 01 February 2000

In vivo biotinylation of the vasculature in B-cell lymphoma identifies BST-2 as a target for antibody-based therapy

scientific article

Incorporation of adult organ-derived endothelial cells into tumor blood vessel

scientific article published in June 2003

Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.

scientific article

Limited expression of reticulocalbin-1 in lymphatic endothelial cells in lung tumor but not in normal lung

scientific article published on January 25, 2011

Liver-specific microRNAs as biomarkers of nanomaterial-induced liver damage

scientific article published on 12 September 2013

Molecular design of conjugated tumor necrosis factor-alpha: synthesis and characteristics of polyvinyl pyrrolidone modified tumor necrosis factor-alpha

scientific article published on 01 April 1999

Novel TNF-α receptor 1 antagonist treatment attenuates arterial inflammation and intimal hyperplasia in mice

scientific article

Novel protein engineering strategy for creating highly receptor-selective mutant TNFs

scientific article published on 13 August 2009

Optimal construction of non-immune scFv phage display libraries from mouse bone marrow and spleen established to select specific scFvs efficiently binding to antigen.

scientific article

Organelle-targeted delivery of biological macromolecules using the protein transduction domain: potential applications for Peptide aptamer delivery into the nucleus.

scientific article

Poly(vinylpyrrolidone-co-dimethyl maleic acid) as a novel renal targeting carrier

scientific article published in March 2004

Potential adjuvant effect of intranasal urban aerosols in mice through induction of dendritic cell maturation.

scientific article

Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice.

scientific article published on 4 March 2011

Protective role of activated protein C in lung and airway remodeling.

scientific article published on May 2004

Protein C inhibitor inhibits breast cancer cell growth, metastasis and angiogenesis independently of its protease inhibitory activity.

scientific article published on September 2007

Proteomic analysis for the development of biopharmaceuticals

scientific article published in January 2013

Proteomic analysis of the hippocampus in Alzheimer's disease model mice by using two-dimensional fluorescence difference in gel electrophoresis

scientific article published on 29 December 2012

Quality enhancement of the non-immune phage scFv library to isolate effective antibodies

scientific article

Regulation of carcinoma cell invasion by protein C inhibitor whose expression is decreased in renal cell carcinoma

scientific article

Role of amino acid residue 90 in bioactivity and receptor binding capacity of tumor necrosis factor mutants

scientific article published on 22 May 2007

Selective enhancer of tumor vascular permeability for optimization of cancer chemotherapy.

scientific article published on March 2004

Silica and titanium dioxide nanoparticles cause pregnancy complications in mice

scientific article published on 03 April 2011

Simple and highly sensitive assay system for TNFR2-mediated soluble- and transmembrane-TNF activity

scientific article published on 26 March 2008

Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant

scientific article

Surface modification of amorphous nanosilica particles suppresses nanosilica-induced cytotoxicity, ROS generation, and DNA damage in various mammalian cells

scientific article

Synthesis of a poly(vinylpyrrolidone-co-dimethyl maleic anhydride) co-polymer and its application for renal drug targeting

scientific article published on 03 March 2003

Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application

scientific article published on January 22, 2011

TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant

scientific article published on 4 May 2009

The targeting of anionized polyvinylpyrrolidone to the renal system.

scientific article published in August 2004

The therapeutic effect of TNFR1-selective antagonistic mutant TNF-alpha in murine hepatitis models

scientific article published on 23 September 2008

The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF

scientific article published on 17 September 2009

The use of PVP as a polymeric carrier to improve the plasma half-life of drugs.

scientific article published on July 2004

The use of a mutant TNF-alpha as a vaccine adjuvant for the induction of mucosal immune responses

scientific article published on 30 July 2009

Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice

[Anticardiolipin antibody (aCL)]

scientific article published on 01 December 2004

[Molecular marker for anticoagulant protein C pathway (APC-PCI complex)]

scientific article published on 01 December 2004

[Techniques for rapid production of monoclonal antibodies for use with antibody technology]

scientific article published on 01 January 2012