List of works - Scott Earley

(Sub)family feud: crosstalk between TRPC channels in vascular smooth muscle cells during vasoconstrictor agonist stimulation.

scientific article

48-h Hypoxic exposure results in endothelium-dependent systemic vascular smooth muscle cell hyperpolarization

scientific article

A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.

scientific article

A TRPC3 signalling complex promotes cerebral artery remodelling during hypertension.

scientific article published on 27 November 2015

A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation

scientific article

Basal protein kinase Cδ activity is required for membrane localization and activity of TRPM4 channels in cerebral artery smooth muscle cells

scientific journal article

Ca(V)3.2 channels and the induction of negative feedback in cerebral arteries.

scientific article published in August 2014

Ca2+ release from the sarcoplasmic reticulum is required for sustained TRPM4 activity in cerebral artery smooth muscle cells.

scientific article

Calcineurin/nuclear factor of activated T cells-coupled vanilliod transient receptor potential channel 4 ca2+ sparklets stimulate airway smooth muscle cell proliferation

scientific article

Central role of Ca2+-dependent regulation of vascular tone in vivo

scientific article published in July 2006

Control of urinary bladder smooth muscle excitability by the TRPM4 channel modulator 9-phenanthrol

scientific article published on 13 September 2013

Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteries

scientific journal article

Cytochrome p-450 epoxygenase products contribute to attenuated vasoconstriction after chronic hypoxia

scientific article published on 6 March 2003

Developmental differences in pulmonary eNOS expression in response to chronic hypoxia in the rat.

scientific article published in July 2002

Disruption of smooth muscle gap junctions attenuates myogenic vasoconstriction of mesenteric resistance arteries

scientific journal article

Distribution and evolution of sequence characteristics in the E. coli genome

scientific article published in October 1986

Dopaminergic neurotoxicants cause biphasic inhibition of purinergic calcium signaling in astrocytes

scientific article

Endogenous cytosolic Ca(2+) buffering is necessary for TRPM4 activity in cerebral artery smooth muscle cells

scientific article published on 7 December 2011

Endothelial control of vasodilation: integration of myoendothelial microdomain signalling and modulation by epoxyeicosatrienoic acids

scientific article published on 08 June 2013

Endothelium-dependent Cerebral Artery Dilation Mediated by Transient Receptor Potential and Ca2+-activated K+ Channels ⬇️

scientific article published on February 1, 2011

Endothelium-dependent blunting of myogenic responsiveness after chronic hypoxia

scientific article published in December 2002

Endothelium-dependent cerebral artery dilation mediated by TRPA1 and Ca2+-Activated K+ channels

scientific article

Estradiol attenuates hypoxia-induced pulmonary endothelin-1 gene expression

scientific journal article

Hypoxia-induced pulmonary endothelin-1 expression is unaltered by nitric oxide

scientific article published in March 2002

Identification of polypeptides encoded by cloned pJM1 iron uptake DNA isolated from Vibrio anguillarum 775

scientific article

Increased nitric oxide production following chronic hypoxia contributes to attenuated systemic vasoconstriction

scientific article published on 2 January 2003

Isolation and Cannulation of Cerebral Parenchymal Arterioles

scientific article published on 23 May 2016

Local regulation of arterial L-type calcium channels by reactive oxygen species.

scientific article

Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation

scientific article

Microtubule structures underlying the sarcoplasmic reticulum support peripheral coupling sites to regulate smooth muscle contractility

scientific article published on 19 September 2017

Molecular Diversity of Receptor Operated Channels in Vascular Smooth Muscle

scientific article published on 23 June 2006

Nanoscale coupling of junctophilin-2 and ryanodine receptors regulates vascular smooth muscle cell contractility

scientific article published on 07 October 2019

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

article published in the Proceedings of the National Academy of Sciences of the United States of America

Neuron-specific (pro)renin receptor knockout prevents the development of salt-sensitive hypertension

scientific article

Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke

No Static at All: Tuning Into the Complexities of Ca2+ Signaling in the Endothelium

scientific article published on April 2016

Novel role for the transient potential receptor melastatin 4 channel in guinea pig detrusor smooth muscle physiology

scientific article published on 9 January 2013

Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells

scientific article

Overexpression of the Neuronal Human (Pro)renin Receptor Mediates Angiotensin II-Independent Blood Pressure Regulation in the Central Nervous System

scientific article published on 15 December 2017

Pharmacological inhibition of TRPM4 hyperpolarizes vascular smooth muscle

scientific journal article

Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstriction

Protein kinase C regulates vascular myogenic tone through activation of TRPM4.

scientific article published on 9 February 2007

Recruitment of dynamic endothelial Ca2+ signals by the TRPA1 channel activator AITC in rat cerebral arteries

scientific article

Redox regulation of transient receptor potential channels in the endothelium

scientific article published on 3 November 2016

Reduction in TRPC4 expression specifically attenuates G-protein coupled receptor-stimulated increases in intracellular calcium in human myometrial cells

scientific article

Regulation of cerebral artery smooth muscle membrane potential by Ca²⁺-activated cation channels

scientific article published on May 2013

Robust internal elastic lamina fenestration in skeletal muscle arteries

scientific article

SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract

scientific article published on 12 June 2018

Serotonin receptors take the TRiPV4 highway in chronic hypoxic pulmonary hypertension. Focus on "TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension

scientific article published on 24 July 2013

Smooth Muscle Cell Ca2+: Think Locally, Act Globally ⬇️

scientific article published on May 1, 2013

TRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarization

scientific article

TRPA1 channels in the vasculature ⬇️

scientific article published on September 1, 2012

TRPC3 mediates pyrimidine receptor-induced depolarization of cerebral arteries

scientific article published on 16 December 2004

TRPM4 channel: a new player in urinary bladder smooth muscle function in rats

scientific article published on 2 January 2013

TRPM4 channels in smooth muscle function ⬇️

scientific article published on February 27, 2013

TRPML1 channels initiate Ca2+ sparks in vascular smooth muscle cells

scientific article published on 23 June 2020

TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels.

scientific article published on 3 November 2005

TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure

scientific article published on 17 July 2009

TRPs in the kidney - location, location, location

scientific article published on 18 October 2014

The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells

scientific article published on 5 May 2017

The intracellular Ca2+ release channel TRPML1 regulates lower urinary tract smooth muscle contractility

scientific article published on 16 November 2020

Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow.

scientific article

Transient receptor potential channels and vascular function

scientific article published on 07 April 2010

Transient receptor potential channels in the vasculature

scientific article

Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.

scientific article

Vanilloid and melastatin transient receptor potential channels in vascular smooth muscle

scientific article published on May 2010

Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells

scientific article

List of works by Scott Earley

(Sub)family feud: crosstalk between TRPC channels in vascular smooth muscle cells during vasoconstrictor agonist stimulation.

48-h Hypoxic exposure results in endothelium-dependent systemic vascular smooth muscle cell hyperpolarization

A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.

A TRPC3 signalling complex promotes cerebral artery remodelling during hypertension.

A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation

Basal protein kinase Cδ activity is required for membrane localization and activity of TRPM4 channels in cerebral artery smooth muscle cells

Ca(V)3.2 channels and the induction of negative feedback in cerebral arteries.

Ca2+ release from the sarcoplasmic reticulum is required for sustained TRPM4 activity in cerebral artery smooth muscle cells.

Calcineurin/nuclear factor of activated T cells-coupled vanilliod transient receptor potential channel 4 ca2+ sparklets stimulate airway smooth muscle cell proliferation

Central role of Ca2+-dependent regulation of vascular tone in vivo

Control of urinary bladder smooth muscle excitability by the TRPM4 channel modulator 9-phenanthrol

Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteries

Cytochrome p-450 epoxygenase products contribute to attenuated vasoconstriction after chronic hypoxia

Developmental differences in pulmonary eNOS expression in response to chronic hypoxia in the rat.

Disruption of smooth muscle gap junctions attenuates myogenic vasoconstriction of mesenteric resistance arteries

Distribution and evolution of sequence characteristics in the E. coli genome

Dopaminergic neurotoxicants cause biphasic inhibition of purinergic calcium signaling in astrocytes

Endogenous cytosolic Ca(2+) buffering is necessary for TRPM4 activity in cerebral artery smooth muscle cells

Endothelial control of vasodilation: integration of myoendothelial microdomain signalling and modulation by epoxyeicosatrienoic acids

Endothelium-dependent Cerebral Artery Dilation Mediated by Transient Receptor Potential and Ca2+-activated K+ Channels ⬇️

Endothelium-dependent blunting of myogenic responsiveness after chronic hypoxia

Endothelium-dependent cerebral artery dilation mediated by TRPA1 and Ca2+-Activated K+ channels

Estradiol attenuates hypoxia-induced pulmonary endothelin-1 gene expression

Hypoxia-induced pulmonary endothelin-1 expression is unaltered by nitric oxide

Identification of polypeptides encoded by cloned pJM1 iron uptake DNA isolated from Vibrio anguillarum 775

Increased nitric oxide production following chronic hypoxia contributes to attenuated systemic vasoconstriction

Isolation and Cannulation of Cerebral Parenchymal Arterioles

Local regulation of arterial L-type calcium channels by reactive oxygen species.

Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation

Microtubule structures underlying the sarcoplasmic reticulum support peripheral coupling sites to regulate smooth muscle contractility

Molecular Diversity of Receptor Operated Channels in Vascular Smooth Muscle

Nanoscale coupling of junctophilin-2 and ryanodine receptors regulates vascular smooth muscle cell contractility

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

Neuron-specific (pro)renin receptor knockout prevents the development of salt-sensitive hypertension

Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke

No Static at All: Tuning Into the Complexities of Ca2+ Signaling in the Endothelium

Novel role for the transient potential receptor melastatin 4 channel in guinea pig detrusor smooth muscle physiology

Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells

Overexpression of the Neuronal Human (Pro)renin Receptor Mediates Angiotensin II-Independent Blood Pressure Regulation in the Central Nervous System

Pharmacological inhibition of TRPM4 hyperpolarizes vascular smooth muscle

Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstriction

Protein kinase C regulates vascular myogenic tone through activation of TRPM4.

Recruitment of dynamic endothelial Ca2+ signals by the TRPA1 channel activator AITC in rat cerebral arteries

Redox regulation of transient receptor potential channels in the endothelium

Reduction in TRPC4 expression specifically attenuates G-protein coupled receptor-stimulated increases in intracellular calcium in human myometrial cells

Regulation of cerebral artery smooth muscle membrane potential by Ca²⁺-activated cation channels

Robust internal elastic lamina fenestration in skeletal muscle arteries

SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract

Serotonin receptors take the TRiPV4 highway in chronic hypoxic pulmonary hypertension. Focus on "TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension

Smooth Muscle Cell Ca2+: Think Locally, Act Globally ⬇️

TRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarization

TRPA1 channels in the vasculature ⬇️

TRPC3 mediates pyrimidine receptor-induced depolarization of cerebral arteries

TRPM4 channel: a new player in urinary bladder smooth muscle function in rats

TRPM4 channels in smooth muscle function ⬇️

TRPML1 channels initiate Ca2+ sparks in vascular smooth muscle cells

TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels.

TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure

TRPs in the kidney - location, location, location

The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells

The intracellular Ca2+ release channel TRPML1 regulates lower urinary tract smooth muscle contractility

Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow.

Transient receptor potential channels and vascular function

Transient receptor potential channels in the vasculature

Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.

Vanilloid and melastatin transient receptor potential channels in vascular smooth muscle

Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells