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List of works by Pelayo Camps

(+/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration.

scientific article published in December 2004

3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates

scientific article

A study on the solid–solid phase transitions of (E)- and (Z)-9-(bicyclo[4.2.1]nonan-9-ylidene)bicyclo[4.2.1]nonane and some related compounds. Assignment of the configuration to the product of monoepoxidation of (E)-9-(bicyclo[4.2.1]non-3-en-9-ylid

A synthesis of levetiracetam based on (S)-N-phenylpantolactam as a chiral auxiliary

Acetylcholinesterase triggers the aggregation of PrP 106-126

scientific article published on 24 May 2006

Alternative Access to Functionalized 2,8-Ethanonoradamantane Derivatives.

scientific article published on 31 May 2017

Alternative syntheses of the new D2d symmetric tetramethyl tricyclo- [3.3.0.0(3,7)]octane-1,3,5,7-tetracarboxylate.

scientific article published in October 2003

An Entry to Functionalized 2,8-Ethanonoradamantane Derivatives

scientific article published on 10 December 2012

An investigation of behavioral effects of Huprine X, a new potent anticholinesterasic, compared with Huperzine-A in 3xTgAD mice

Behavioural effects and regulation of PKCalpha and MAPK by huprine X in middle aged mice

scientific article published on 2 April 2010

Binding of 13-Amidohuprines to Acetylcholinesterase: Exploring the Ligand-Induced Conformational Change of the Gly117-Gly118 Peptide Bond in the Oxyanion Hole

scientific article published in November 2006

Characterisation of the anticholinesterase activity of two new tacrine-huperzine A hybrids

scientific article published in May 2003

ChemInform Abstract: Cross Metathesis of Several Methylenecyclopentane Derivatives

Cholesterol-diaryl ketone stereoisomeric dyads as models for "clean" type I and type II photooxygenation mechanisms

scientific article

Cholinergic drugs in pharmacotherapy of Alzheimer's disease.

scientific article

Corrigendum to “Straightforward preparation of enantiopure 3-amino-4,4-dimethylpyrrolidin-2-one and derivatives” [Tetrahedron: Asymmetry 21 (2010) 2124]

scholarly article published in Tetrahedron: Asymmetry

Cross metathesis of several methylenecyclopentane derivatives

article published in 2013

Cross-Coupling of Highly Pyramidalized Alkenes:  A Straightforward Access to Functionalized Tetrasecododecahedradienes

scientific article published on 01 December 2000

Cross-coupling of a functionalized highly pyramidalized alkene: DSC and NMR study of the [2+2] retrocycloaddition of cyclobutane cross products, hyperstability and pyramidalization of the formed dienes

Dehalogenation of 1,3-diiodotricyclo[3.3.0.0(3,7)]octane: generation of 1,3-dehydrotricyclo[3.3.0.0(3,7)]octane, a 2,5-methano-bridged [2.2.1]propellane

scientific article published in January 2007

Diastereoselective preparation of (S)-(1,4,4-trimethylpyrrolidin-3-yl)amine, a new chiral 1,2-diamine for thiourea-type organocatalysts

Dimeric and hybrid anti-Alzheimer drug candidates

scientific article

Double Methylenecyclopentane Annulation of Succinimides: Easy Access to 3,7-Dioxobicyclo[3.3.0]octane-1,5-dicarboximides

article by Pelayo Camps et al published June 2009 in European Journal of Organic Chemistry

EASY ACCESS TO 4-SUBSTITUTED (±)-HUPERZINE A ANALOGUES

article by Pelayo Camps et al published January 2001 in Synthetic Communications

Easy and General Method for the Preparation ofm- andp-Acylbenzoic Acids: A New Synthesis ofrac-Suprofen

article by Pelayo Camps et al published 14 June 1993 in Liebigs Annalen der Chemie

Editorial [Hot Topic: Alzheimer Drug Design Based on the Amyloid Hypothesis (Executive Editors: D. Munoz-Torrero and P. Camps)]

Effect of acetylcholinesterase inhibitors on AChE-induced PrP106-126 aggregation

scientific article published on 01 January 2006

Effect of huprine X on β-amyloid, synaptophysin and α7 neuronal nicotinic acetylcholine receptors in the brain of 3xTg-AD and APPswe transgenic mice

scientific article published on 4 August 2010

Effect ofN-substituents on the13C NMR parameters of azoles

article

Effects of (+/-)-huprine Y and (+/-)-huprine Z, two new anticholinesterasic drugs, on muscarinic receptors

scientific article published on 20 January 2005

Efficient and Selective Photogeneration of Cholesterol-Derived Radicals by Intramolecular Hydrogen Abstraction in Model Dyads

article

Evaluation of cryptolepine and huperzine derivatives as lead compounds towards new agents for the treatment of human African trypanosomiasis.

scientific article

Expanding the multipotent profile of huprine-tacrine heterodimers as disease-modifying anti-Alzheimer agents

scientific article

Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus

scientific article published on 05 April 2011

Generation and Reactions of an Octacyclic Hindered Pyramidalized Alkene

scientific article published on 27 April 2018

Generation and reactions of two new functionalized tricyclo[3.3.0.0 3,7]oct-1(5)-ene derivatives.

scientific article

Generation, Trapping, and Dimerization of Pentacyclo[6.4.0.02,10.03,7.04,9]dodeca-5,8,11-triene: An Uncatalyzed Thermal[2+2+2+2] Cycloaddition

Highly diastereoselective one-pot synthesis of spiro[cyclopenta[a]indene-2,2'-indene]diones from 1-indanones and aromatic aldehydes

scientific article published on 01 April 2006

Huprine X and huperzine A improve cognition and regulate some neurochemical processes related with Alzheimer's disease in triple transgenic mice (3xTg-AD).

scientific article published on 24 May 2012

Huprine X is a novel high-affinity inhibitor of acetylcholinesterase that is of interest for treatment of Alzheimer's disease

scientific article published in February 2000

Huprine-tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer's and prion diseases

scientific article

Huprines as a new family of dual acting trypanocidal-antiplasmodial agents

scientific article

Huprines for Alzheimer's disease drug development ⬇️

scientific article published on January 1, 2008

Improved synthesis of a functionalized 2,8-ethanonoradamantane derivative

article published in 2014

Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice

scientific article published on 04 September 2018

Neuroprotective effects of (+/-)-huprine Y on in vitro and in vivo models of excitoxicity damage

scientific article published in April 2003

New Applications of Dimethyl Pentacyclo[6.4.0.02,10.03,7.04,9]dodeca-5,11-diene-8,9-dicarboxylate in the Synthesis of Polycyclic Compounds

New dimers from the decomposition of α-lithio-N-nitrosamines. Evidence for no− elimination

article

Nicotinic-receptor potentiator drugs, huprine X and galantamine, increase ACh release by blocking AChE activity but not acting on nicotinic receptors

scientific article

Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.

scientific article published on 3 June 2008

Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates

scientific article

On the Reaction of 1,3-Diphenylisobenzofuran and (2-Iodoethynyl)(phenyl)iodonium Triflate. A Unique Case of Oxygen Transfer from the Diels-Alder Adduct to the Diene

scientific article published on 25 July 2012

On the Synthesis of 2-Amino-4,6-difluorobenzonitrile: Highly Selective Formation of 5-Fluoro-3-nitro-1,2-benzoquinone 2-Diazide in the Attempted Sandmeyer Cyanation of 2,4-Difluoro-6-nitrobenzenediazonium Cation†

On the regioselectivity of the Friedländer reaction leading to huprines: stereospecific acid-promoted isomerization of syn-huprines to their anti-regioisomers

One-pot synthesis of N-substituted pantolactams from pantolactone

Polycyclic N-benzamido imides with potent activity against vaccinia virus.

scientific article published on December 2010

Potentiation effects of (+/-)huprine X, a new acetylcholinesterase inhibitor, on nicotinic receptors in rat cortical synaptosomes

scientific article published on January 2004

Preface [Hot Topic: Current Trends in the Development of Acetylcholinesterase Inhibitors as Anti-Alzheimer Agents (Executive Editors: P. Camps and D. Munoz-Torrero)]

Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds

scientific article published in September 2009

Role of the viral hemagglutinin in the anti-influenza virus activity of newly synthesized polycyclic amine compounds.

scientific article published on 22 June 2013

STEREOSELECTIVE SYNTHESIS OF DIMETHYL TETRACYCLO[5.2.1.02.6.03.8]DECANE-7,8-DICARBOXYLATE

Straightforward Synthesis of a Vicinal Double-Bridgehead Iodo Trimethylsilyl Octacycle: Unprecedented Lack of Reactivity of the Silyl Group in the Presence of Fluoride Anions

Straightforward preparation of enantiopure 3-amino-4,4-dimethylpyrrolidin-2-one and its derivatives

Studies related to the synthesis of dimethyl tetracyclo[5.2.1.02,6.03,8]decane-7,8-dicarboxylate

Synthesis and Applications of (R)- and (S)-Pantolactone as Chiral Auxiliaries

Synthesis and Reactions of 7-Oxonorbornane-2,3-dicarboximides

Synthesis and absolute configuration of novel N,O-psiconucleosides using (R)-N-phenylpantolactam as a resolution agent

scientific article published on 29 July 2008

Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease

scientific article published in April 1998

Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines.

scientific article published on 13 February 2009

Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors

scientific article published on 01 March 2005

Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs

scientific article

Synthesis of both enantiomers of baclofen using (R)- and (S)-N-phenylpantolactam as chiral auxiliaries

Synthesis of bridgehead polycyclic 1,2-diamines and 2-amino alcohol derivatives as Rigid acetylcholine analogs

Synthesis, Chemical Trapping, and Dimerization of 3,7-Dimethyltricyclo[3.3.0.03, 7]oct-1(5)-ene:[2+ 2] Retrocycloaddition of the Cyclobutane Dimer

Synthesis, Conformational Analysis and Transannular Reactions of 5,9-Propanobenzo[7]annulene Derivatives

Synthesis, chemical trapping and dimerization of tricyclo[3.3.0.03,7]oct-1(5)-ene, the consummate member of a series of pyramidalized alkenes

Synthesis, in Vitro Pharmacology, and Molecular Modeling of Very Potent Tacrine−Huperzine A Hybrids as Acetylcholinesterase Inhibitors of Potential Interest for the Treatment of Alzheimer's Disease

scientific article published in August 1999

Synthesis, in vitro pharmacology, and molecular modeling of syn-huprines as acetylcholinesterase inhibitors.

scientific article published in December 2001

Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates.

scientific article published on 16 February 2010

The IUPAC systematic names of the regular polyhedranes: An exercise in organic chemistry nomenclature

The pharmacology of novel acetylcholinesterase inhibitors, (+/-)-huprines Y and X, on the Torpedo electric organ

scientific article published in June 2001

Undifferentiated and differentiated PC12 cells protected by huprines against injury induced by hydrogen peroxide

scientific article

π−π-Interactions in Pentacyclo- [8.2.1.1.2,51.4,718,11]hexadeca-1,7-diene

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