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List of works by Christoph Loenarz

2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2.

scientific article published on 6 September 2009

An Oxygen Sensation: Progress in Macromolecule Hydroxylation Triggered by the Elucidation of Cellular Oxygen Sensing

scientific article published on 21 January 2020

Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.

scientific article

Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal

article published in 2018

Chemical basis for the selectivity of the von Hippel Lindau tumor suppressor pVHL for prolyl-hydroxylated HIF-1alpha

scientific article published on August 2010

Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study.

scientific article published on 26 January 2008

Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase

scientific article

Evaluation of aspirin metabolites as inhibitors of hypoxia-inducible factor hydroxylases

scientific article

Evidence for a stereoelectronic effect in human oxygen sensing.

scientific article

Expanding chemical biology of 2-oxoglutarate oxygenases

scientific article

Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α)

scientific article

Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy

scientific article

Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2)

scientific article

Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates

scientific article published on 15 November 2010

Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases

scientific article

Mutations to metabolic enzymes in cancer herald a need to unify genetics and biochemistry ⬇️

scientific article published on September 1, 2011

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

scientific article

Oxygenase catalyzed 5-methylcytosine hydroxylation

scientific article

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

scientific article

Oxygenases for oxygen sensing

PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase

scientific article

Photoactivable peptides for identifying enzyme–substrate and protein–protein interactions

scientific article published on 13 December 2010

Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases ⬇️

scientific article published on August 20, 2010

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha

scientific article

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

scientific article published on 08 January 2019

Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family

scientific article

Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor

scientific article

Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases

scientific article

Structural studies on human 2-oxoglutarate dependent oxygenases

scientific article

Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase

scientific article

Structure of the ribosomal oxygenase OGFOD1 provides insights into the regio- and stereoselectivity of prolyl hydroxylases

scientific article

Studies on the Substrate Selectivity of the Hypoxia-Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain

scientific article published on 26 September 2018

Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth.

scientific article published on 18 February 2014

The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens

scientific article (publication date: 2011)

YcfDRM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase

scientific article published on 9 March 2018

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