List of works - Helen J. McBride

A Review of the Totality of Evidence Supporting the Development of the First Adalimumab Biosimilar ABP 501

scientific article published on 10 June 2019

Analytical and functional similarity of Amgen biosimilar ABP 215 to bevacizumab.

scientific article published on 19 March 2018

Assessing Analytical and Functional Similarity of Proposed Amgen Biosimilar ABP 980 to Trastuzumab.

scientific article

Bone CLARITY: Clearing, imaging, and computational analysis of osteoprogenitors within intact bone marrow

scientific article published in April 2017

Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex

scientific article published on 01 May 2019

Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase

scientific article

Discovery and in vivo evaluation of dual PI3Kβ/δ inhibitors

scientific article

Discovery of pyridazinopyridinones as potent and selective p38 mitogen-activated protein kinase inhibitors

scientific article published on September 2010

Expression of ORAII, a plasma membrane resident subunit of the CRAC channel, in rodent and non-rodent species

scientific article

Generation and Characterization of Fully Human Monoclonal Antibodies Against Human Orai1 for Autoimmune Disease

scientific article published on 08 March 2013

Impact of Precipitation of Antibody Therapeutics After Subcutaneous Injection on Pharmacokinetics and Immunogenicity

scientific article published on 23 January 2019

Inhibition of CRAC with a human anti-ORAI1 monoclonal antibody inhibits T-cell-derived cytokine production but fails to inhibit a T-cell-dependent antibody response in the cynomolgus monkey

scientific article published on 3 July 2014

Interactions between Pho85 cyclin-dependent kinase complexes and the Swi5 transcription factor in budding yeast

scientific article published on 01 February 2000

Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform.

scientific article

Murine collagen antibody induced arthritis (CAIA) and primary mouse hepatocyte culture as models to study cytochrome P450 suppression

scientific article published on 10 March 2012

Novel protein therapeutic joint retention strategy based on collagen-binding Avimers

scientific article published on 3 October 2017

Nuclear imaging of autoimmunity: focus on IBD and RA.

scientific article

ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense

scientific article published on 14 September 2020

Orai1 enhances muscle endurance by promoting fatigue-resistant type I fiber content but not through acute store-operated Ca2+ entry.

scientific article published in September 2016

Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase

scientific article

Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells

scientific article

Surface imaging microscopy, an automated method for visualizing whole embryo samples in three dimensions at high resolution

scientific article published in November 2002

The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae

scientific article published on 01 October 2001

Totality of evidence in the development of ABP 215, an approved bevacizumab biosimilar

scientific article published on 26 September 2019

Wnt signaling components in the chicken intestinal tract

scientific article published on April 2003

List of works by Helen J. McBride

A Review of the Totality of Evidence Supporting the Development of the First Adalimumab Biosimilar ABP 501

Analytical and functional similarity of Amgen biosimilar ABP 215 to bevacizumab.

Assessing Analytical and Functional Similarity of Proposed Amgen Biosimilar ABP 980 to Trastuzumab.

Bone CLARITY: Clearing, imaging, and computational analysis of osteoprogenitors within intact bone marrow

Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex

Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase

Discovery and in vivo evaluation of dual PI3Kβ/δ inhibitors

Discovery of pyridazinopyridinones as potent and selective p38 mitogen-activated protein kinase inhibitors

Expression of ORAII, a plasma membrane resident subunit of the CRAC channel, in rodent and non-rodent species

Generation and Characterization of Fully Human Monoclonal Antibodies Against Human Orai1 for Autoimmune Disease

Impact of Precipitation of Antibody Therapeutics After Subcutaneous Injection on Pharmacokinetics and Immunogenicity

Inhibition of CRAC with a human anti-ORAI1 monoclonal antibody inhibits T-cell-derived cytokine production but fails to inhibit a T-cell-dependent antibody response in the cynomolgus monkey

Interactions between Pho85 cyclin-dependent kinase complexes and the Swi5 transcription factor in budding yeast

Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform.

Murine collagen antibody induced arthritis (CAIA) and primary mouse hepatocyte culture as models to study cytochrome P450 suppression

Novel protein therapeutic joint retention strategy based on collagen-binding Avimers

Nuclear imaging of autoimmunity: focus on IBD and RA.

ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense

Orai1 enhances muscle endurance by promoting fatigue-resistant type I fiber content but not through acute store-operated Ca2+ entry.

Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase

Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells

Surface imaging microscopy, an automated method for visualizing whole embryo samples in three dimensions at high resolution

The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae

Totality of evidence in the development of ABP 215, an approved bevacizumab biosimilar

Wnt signaling components in the chicken intestinal tract