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List of works by Robert Eferl

A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions

scientific article published on 22 August 2019

A dual role for interferon γ signalling in hepatocellular carcinoma ⬇️

scientific article published on 07 August 2012

A mouse model to identify cooperating signaling pathways in cancer

article

A mouse tool for conditional mutagenesis in ovarian granulosa cells.

scientific article published on October 2010

AKT3 drives adenoid cystic carcinoma development in salivary glands

scientific article published on 28 December 2017

AP-1: a double-edged sword in tumorigenesis

scientific article (publication date: November 2003)

Acquisition of an immunosuppressive protumorigenic macrophage phenotype depending on c-Jun phosphorylation

scientific article

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease

scientific article published on 18 January 2008

Afatinib restrains K-RAS–driven lung tumorigenesis

scientific article published on 01 June 2018

Altered microtubule-associated tau messenger RNA isoform expression in livers of griseofulvin- and 3,5-diethoxycarbonyl-1, 4-dihydrocollidine-treated mice

scientific article

Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma.

scientific article

Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression.

scientific article published on 29 May 2017

Bacterial artificial chromosomes improve recombinant protein production in mammalian cells.

scientific article

Bone cell differentiation and the role of Fos/AP-1 proteins.

scientific article

CCL2 at the crossroad of cancer metastasis

scientific article published on April 2013

CDK4/6 inhibition and sorafenib: a ménage à deux in HCC therapy?

scientific article published on 5 January 2017

Chromosomal instability in HCC: a key function for checkpoint kinase 2.

scientific article published on 5 May 2017

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

scientific article published on 21 August 2018

Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1.

scholarly article

Deviations of the immune cell landscape between healthy liver and hepatocellular carcinoma

scientific article published on 18 April 2018

Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis

scientific article

Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.

scientific article

Distinct functions of junD in cardiac hypertrophy and heart failure

scientific article

EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients

scientific article published on 8 April 2017

Epidermal growth factor signaling protects from cholestatic liver injury and fibrosis

scientific article

Erratum: STAT3 regulated ARF expression suppresses prostate cancer metastasis

scientific article published in Nature Communications

Fos/AP-1 proteins in bone and the immune system

scientific article

Functions of c-Jun in liver and heart development

scientific journal article

Generation of metastatic melanoma specific antibodies by affinity purification

scientific article

Genetically modified mouse models of cancer invasion and metastasis

scientific article published on July 2011

Growth hormone resistance exacerbates cholestasis-induced murine liver fibrosis.

scientific article published on February 2015

Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge

scientific article published on 31 August 2009

IDO1+ Paneth cells promote immune escape of colorectal cancer

scientific article published on 22 May 2020

IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis

scientific article published on 29 September 2019

Impact of glutathione peroxidase 4 on cell proliferation, angiogenesis and cytokine production in hepatocellular carcinoma

scientific article published on 22 January 2018

Inducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivo

scientific article

Induction of DNA synthesis in primary mouse hepatocytes is associated with nuclear pro-transforming growth factor alpha and erbb-1 and is independent of c-jun

scientific article published on May 2003

Induction of colorectal cancer in mice and histomorphometric evaluation of tumors

scientific article

Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin

scientific article published on 24 February 2014

JAK-STAT inhibition impairs K-RAS-driven lung adenocarcinoma progression

scientific article published on 10 September 2019

JAK-STAT signaling in hepatic fibrosis.

scientific article published on June 2011

Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53

scientific article (publication date: 24 January 2003)

Meprinβ, a novel mediator of vascular remodelling underlying pulmonary hypertension

scientific article published on 31 January 2014

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

scientific journal article

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

scientific article published in December 2011

Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1

scientific article published on 01 February 2019

Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition.

scientific article published on 28 March 2016

Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice

scientific article published on 22 January 2015

NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.

scientific article

Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia

scientific article published on 11 June 2008

PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas

scientific article

PhiC31-mediated cassette exchange into a bacterial artificial chromosome.

scientific article published in November 2007

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

scientific article

Rhabdomyosarcoma development in mice lacking Trp53 and Fos

article

Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation

article

STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.

scientific article

STAT3 regulated ARF expression suppresses prostate cancer metastasis

scientific article published on 22 July 2015

STAT3β controls inflammatory responses and early tumor onset in skin and colon experimental cancer models.

scientific article

Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis

article

Simultaneous generation offra-2 conditional andfra-2 knock-out mice

article

Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) mice

scientific article

The AP1 transcription factor Fra2 is required for efficient cartilage development.

scientific article published in November 2004

The Fos-related antigen Fra-1 is an activator of bone matrix formation

scientific article

The tumor-associated shift in immunoglobulin G1/G2 is expressed at the messenger RNA level of peripheral blood B lymphocytes in patients with gynecologic malignancies

scientific article published on 01 January 2000

The use of bacterial artificial chromosomes for recombinant protein production in mammalian cell lines

scientific article

c-Jun regulates eyelid closure and skin tumor development through EGFR signaling

scientific article published on June 2003

c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity

scientific article

cDNA cloning and analysis of tissue-specific expression of mouse peroxisomal straight-chain acyl-CoA oxidase

scientific article published in February 2000

p19(ARF) /p14(ARF) controls oncogenic functions of signal transducer and activator of transcription 3 in hepatocellular carcinoma

scientific article published in July 2011

p21Waf1/Cip1 revisited: oncogenic function in hepatocellular carcinoma

scientific article published on 12 November 2013

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