List of works by Emilio Casanova

A CamKIIalpha iCre BAC allows brain-specific gene inactivation.

scientific article published on September 2001

A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions

scientific article published on 22 August 2019

A mouse model for visualization of GABA(B) receptors.

scientific article published in September 2009

A mouse model to identify cooperating signaling pathways in cancer

article

A mouse tool for conditional mutagenesis in ovarian granulosa cells.

scientific article published on October 2010

A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development

scientific article published on 2 December 2010

AKT3 drives adenoid cystic carcinoma development in salivary glands

scientific article published on 28 December 2017

Afatinib restrains K-RAS–driven lung tumorigenesis

scientific article published on 01 June 2018

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

scientific article published on 14 June 2018

Analysis of splicing of four mouse JNK/SAPKalpha variants

scientific article published on 01 February 2000

Bacterial artificial chromosomes improve recombinant protein production in mammalian cells.

scientific article

Breaking bad family ties: Pan-ERBB blockers inhibit KRAS driven lung tumorigenesis

scientific article published on 20 September 2018

CB1 cannabinoid receptors and on-demand defense against excitotoxicity

scientific article (publication date: 3 October 2003)

Characterization of the promoter of the mouse c-Jun NH2-terminal/stress-activated protein kinase alpha gene

scientific article published on 01 November 2004

Cloning of chicken and mouse alpha 1b adrenergic receptor

scientific article published in March 1998

Codon-improved Cre recombinase (iCre) expression in the mouse

scientific article (publication date: 2002)

Conditional mutagenesis of CamKIV

scientific article published on 01 February 2002

Construction of a conditional allele of RSK-B/MSK2 in the mouse

scientific article published on 01 February 2002

Differential effect of chronic ethanol treatment on barbiturate and steroid modulation of muscimol-binding to rat brain cortex.

scientific article published in August 1993

Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis

scientific article

Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.

scientific article

ER-based double iCre fusion protein allows partial recombination in forebrain

scientific article published in November 2002

ETV6/RUNX1 induces reactive oxygen species and drives the accumulation of DNA damage in B cells.

scientific article published on November 2013

Epidermal growth factor signaling protects from cholestatic liver injury and fibrosis

scientific article

Exploration of BAC versus plasmid expression vectors in recombinant CHO cells.

scientific article published on 19 October 2012

Expression of Cre recombinase in dopaminoceptive neurons

scientific article

Floxed allele for conditional inactivation of the GABAB(1) gene

scientific article published in November 2004

Generation of a conditional allele of the CBP gene in mouse

scientific article

Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis

scientific journal article

Genetically modified mouse models of cancer invasion and metastasis

scientific article published on July 2011

Growth hormone resistance exacerbates cholestasis-induced murine liver fibrosis.

scientific article published on February 2015

Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man.

scientific article

Heterologous protein production using euchromatin-containing expression vectors in mammalian cells

scientific article published on 14 May 2015

IDO1+ Paneth cells promote immune escape of colorectal cancer

scientific article published on 22 May 2020

Identification of a cyclic adenosine 3',5'-monophosphate-dependent protein kinase phosphorylation site in the carboxy terminal tail of human D1 dopamine receptor

scientific article published on 01 March 1995

Identification of a long huntingtin mRNA transcript in mouse brain

scientific article published in December 1996

Immunodetection of serotonin transporter from mouse brain.

scientific article

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.

scientific article published on October 2011

Inducible site-specific recombination in the brain

scientific article published in January 1999

JAK-STAT inhibition impairs K-RAS-driven lung adenocarcinoma progression

scientific article published on 10 September 2019

JAK-STAT signaling in hepatic fibrosis.

scientific article published on June 2011

Lactotransferrin-Cre reporter mice trace neutrophils, monocytes/macrophages and distinct subtypes of dendritic cells

scientific article published on 21 February 2014

Loss of GABAB receptors in cochlear neurons: threshold elevation suggests modulation of outer hair cell function by type II afferent fibers

scientific article

MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation

scientific article published on 27 May 2019

Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation

scientific article published on 21 June 2016

Modeling cancer using genetically engineered mice.

scientific article

Molecular cloning of alpha 1d-adrenergic receptor and tissue distribution of three alpha 1-adrenergic receptor subtypes in mouse.

scientific article published on December 1995

Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice

scientific article published on 22 January 2015

NMDA receptor-dependent GABAB receptor internalization via CaMKII phosphorylation of serine 867 in GABAB1.

scientific article

Neuronal migration in the murine rostral migratory stream requires serum response factor

scientific article

No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions.

scientific article

Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog.

scientific article published on 25 May 2018

Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma

scientific article published on 01 February 2020

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

scientific article published on 19 January 2019

PhiC31-mediated cassette exchange into a bacterial artificial chromosome.

scientific article published in November 2007

Phosphorylation of the third intracellular loop of the mouse alpha1b-adrenergic receptor by cAMP-dependent protein kinase

scientific article published on 01 January 1997

Powerful expression in Chinese Hamster Ovary cells using bacterial artificial chromosomes: parameters influencing productivity

scientific article

Rapid localization of a gene within BACs and PACs

scientific article published in February 2002

Recent advances in recombinant protein production: BAC-based expression vectors, the bigger the better.

scientific article published on 2 July 2013

STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.

scientific article

STAT3: Versatile Functions in Non-Small Cell Lung Cancer

scientific article published on 29 April 2020

STAT3β is a tumor suppressor in acute myeloid leukemia

scientific article published on 01 July 2019

Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis

article

Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy

scientific article

Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) mice

scientific article

Targeting KRAS Mutant Non-Small-Cell Lung Cancer: Past, Present and Future

scientific article published on 17 June 2020

The Transcription Factor ZNF683/HOBIT Regulates Human NK-Cell Development

scientific article published on 15 May 2017

The use of bacterial artificial chromosomes for recombinant protein production in mammalian cell lines

scientific article

Unexpected oncosuppressive role for STAT3 in KRAS-induced lung tumorigenesis.

scientific article published on 26 May 2015

Validation of an enzyme-linked immunosorbent assay (ELISA) for quantification of endostatin levels in mice as a biomarker of developing glomerulonephritis

scientific article published on 12 August 2019

When reverse genetics meets physiology: the use of site-specific recombinases in mice

scientific article

[CHEK1 expression and inhibitors in TP53 mutant cancer]

scientific article published on 11 November 2019

α Complementation in the Cre recombinase enzyme

article