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List of works by Vincent Kam Wai Wong

(Z)3,4,5,4'-trans-tetramethoxystilbene, a new analogue of resveratrol, inhibits gefitinb-resistant non-small cell lung cancer via selectively elevating intracellular calcium level.

scientific article

2-Aminoethoxydiphenylborane sensitizes anti-tumor effect of bortezomib via suppression of calcium-mediated autophagy.

scientific article published on 2 March 2018

A Functional Variant in Ubiquitin Conjugating Enzyme E2 L3 Contributes to Hepatitis B Virus Infection and Maintains Covalently Closed Circular DNA Stability by Inducing Degradation of Apolipoprotein B mRNA Editing Enzyme Catalytic Subunit 3A

scientific article published on 15 March 2019

A Method for Rapid Screening of Anilide-Containing AMPK Modulators Based on Computational Docking and Biological Validation

scientific article published on 03 July 2018

Advanced research technology for discovery of new effective compounds from Chinese herbal medicine and their molecular targets

scientific article

Antagonizing STAT5B dimerization with an osmium complex

scientific article

Application of artificial neural network to investigate the effects of 5-fluorouracil on ribonucleotides and deoxyribonucleotides in HepG2 cells.

scientific article

Arsenic trioxide reverses the chemoresistance in hepatocellular carcinoma: a targeted intervention of 14-3-3η/NF-κB feedback loop

scientific article published on 20 December 2018

Artemisinin Derivatives Target Topoisomerase 1 and Cause DNA Damage in Silico and in Vitro

scientific article published on 9 October 2017

Aurone derivatives as Vps34 inhibitors that modulate autophagy.

scientific article

Autophagic effects of Chaihu (dried roots of Bupleurum Chinense DC or Bupleurum scorzoneraefolium WILD).

scientific article published on 11 September 2014

Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats

scientific article published on 04 July 2019

Corrigendum: Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity

scientific article published on 25 September 2018

Far infrared radiation induces changes in gut microbiota and activates GPCRs in mice

scientific article published on 23 December 2019

Four Prenylflavone Derivatives with Antiplasmodial Activities from the Stem of Tephrosia purpurea subsp. leptostachya.

scientific article published on 10 September 2017

Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice

scientific article published on 9 November 2016

Identification of inhibitors of the polo-box domain of polo-like kinase 1 from natural and semisynthetic compounds

scientific article published on 15 March 2019

Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins

scientific article published on 24 November 2015

Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity

scientific article published on 13 February 2018

Integrin activation as an alternative treatment approach for inflammatory diseases.

scientific article published on 31 October 2011

Investigation into perturbed nucleoside metabolism and cell cycle for elucidating the cytotoxicity effect of resveratrol on human lung adenocarcinoma epithelial cells

scientific article published on 01 August 2019

Isoliquiritigenin suppresses human T Lymphocyte activation via covalently binding cysteine 46 of IκB kinase.

scientific article published on 10 September 2016

Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells

scientific article published on 23 September 2019

MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate

scientific article published on 10 February 2019

Matrine induces cell anergy in human Jurkat T cells through modulation of mitogen-activated protein kinases and nuclear factor of activated T-cells signaling with concomitant up-regulation of anergy-associated genes expression

scientific article published in January 2010

Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation

scientific article published in May 2009

Method for Quantification of Ribonucleotides and Deoxyribonucleotides in Human Cells Using (Trimethylsilyl)diazomethane Derivatization Followed by Liquid Chromatography-Tandem Mass Spectrometry

scientific article published on 11 December 2018

N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca2+ Mobilization

scientific article

Natural products-based polypharmacological modulation of the peripheral immune system for the treatment of neuropsychiatric disorders

scientific article published on 21 January 2020

Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells.

scientific article published on July 2014

Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells via induction of autophagy.

scientific article published on 18 February 2015

Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism

scientific article published on 27 December 2019

New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of Autophagy

scientific article published on 17 March 2016

Niacin analogue, 6-Aminonicotinamide, a novel inhibitor of hepatitis B virus replication and HBsAg production

scientific article published on 31 October 2019

Novel dauricine derivatives suppress cancer via autophagy-dependent cell death

scientific article published on 02 November 2018

Novel direct AMPK activator suppresses non-small cell lung cancer through inhibition of lipid metabolism.

scientific article published on 9 October 2017

Novel ginsenoside derivative 20(S)-Rh2E2 suppresses tumor growth and metastasis in vivo and in vitro via intervention of cancer cell energy metabolism

scientific article published on 14 August 2020

Novel steroidal saponin isolated from Trillium tschonoskii maxim. exhibits anti-oxidative effect via autophagy induction in cellular and Caenorhabditis elegans models

scientific article published on 16 September 2019

Pathogenesis of thromboangiitis obliterans: Gene polymorphism and immunoregulation of human vascular endothelial cells.

scientific article published on 18 August 2017

Phytotherapy using blueberry leaf polyphenols to alleviate non-alcoholic fatty liver disease through improving mitochondrial function and oxidative defense

scientific article published on 18 March 2020

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer

scientific article published on 13 January 2020

Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer

scientific article published on 09 August 2019

Profiling of ribonucleotides and deoxyribonucleotides pools in response to DNA damage and repair induced by methyl methanesulfonate in cancer and normal cells

scientific article published on 4 October 2017

Profiling ribonucleotide and deoxyribonucleotide pools perturbed by gemcitabine in human non-small cell lung cancer cells

scientific article

Rh2E2, a novel metabolic suppressor, specifically inhibits energy-based metabolism of tumor cells.

scientific article published on 18 January 2016

SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells

scientific article published on 23 January 2020

Saikosaponin-d Enhances the Anticancer Potency of TNF-α via Overcoming Its Undesirable Response of Activating NF-Kappa B Signalling in Cancer Cells

scientific article

Saikosaponin-d, a calcium mobilizing agent, sensitizes chemoresistant ovarian cancer cells to cisplatin-induced apoptosis by facilitating mitochondrial fission and G2/M arrest

scientific article

Semi-synthetic isoflavones as BACE-1 inhibitors against Alzheimer's disease

scientific article published on 15 March 2019

Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death.

scientific article published on 22 February 2017

The Calcium-Induced Regulation in the Molecular and Transcriptional Circuitry of Human Inflammatory Response and Autoimmunity.

scientific article published in January 2017

The New Application of UHPLC-DAD-TOF/MS in Identification of Inhibitors on β-Amyloid Fibrillation From

scientific article published on 18 March 2019

The in vitro structure-related anti-cancer activity of ginsenosides and their derivatives.

scientific article

Total ginsenosides increase coronary perfusion flow in isolated rat hearts through activation of PI3K/Akt-eNOS signaling

scientific article published on 17 August 2010

Transcriptional activity of the promoter region of rat frizzled-related protein gene.

scientific article

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