List of works - Wendy E. Ward

A Mouse Model for Studying Nutritional Programming: Effects of Early Life Exposure to Soy Isoflavones on Bone and Reproductive Health

scientific article

A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood

scientific article published on January 2015

A western-style diet reduces bone mass and biomechanical bone strength to a greater extent in male compared with female rats during development

scientific article published in September 2003

Accessibility of 3H-Secoisolariciresinol Diglycoside Lignan Metabolites in Skeletal Tissue of Ovariectomized Rats

scientific article published on 11 June 2011

Adequate but not supplemental folic acid combined with soy isoflavones during early life improves bone health at adulthood in male mice

scientific article published on 2 May 2013

Adiponectin is a negative regulator of bone mineral and bone strength in growing mice

scientific article

Biomechanical bone strength and bone mass in young male and female rats fed a fish oil diet

scientific article

Bone abnormalities in adolescent leptin-deficient mice

scientific article

Bone development in growing female mice fed calcium and vitamin D at lower levels than is present in the AIN-93G reference diet.

scientific article

Bone mass, bone strength, and their relationship in developing CD-1 mice

scientific article

Bone metabolism and circulating IGF-I and IGFBPs in dexamethasone-treated preterm infants

scientific article published on 01 December 1999

Bone structure is largely unchanged in growing male CD-1 mice fed lower levels of vitamin D and calcium than in the AIN-93G diet

Bone-specific gene expression patterns and whole bone tissue of female mice are programmed by early life exposure to soy isoflavones and folic acid

scientific article published on 28 May 2015

Changes in mitochondrial perilipin 3 and perilipin 5 protein content in rat skeletal muscle following endurance training and acute stimulated contraction

scientific article published on 21 March 2015

Circulating isoflavonoid levels in CD-1 mice: effect of oral versus subcutaneous delivery and frequency of administration

scientific article published on 12 June 2011

Combination of soy protein and high dietary calcium on bone biomechanics and bone mineral density in ovariectomized rats

scientific article published on 21 July 2005

Combined high-fat-resveratrol diet and RIP140 knockout mice reveal a novel relationship between elevated bone mitochondrial content and compromised bone microarchitecture, bone mineral mass, and bone strength in the tibia

scientific article

Comparative Response in Growth and Bone Status to Three Dexamethasone Treatment Regimens in Infant Piglets

scientific article published on 01 August 2000

Comparison of Two Dexamethasone Treatment Regimens on Outcomes of Growth and Bone Metabolism in Piglets † 1523

Comparison of black, green and rooibos tea on osteoblast activity.

scientific article published on February 2016

Comparison of ex vivo and in vivo micro-computed tomography of rat tibia at different scanning settings

scientific article published on 14 September 2016

Conclusion

Daidzein together with high calcium preserve bone mass and biomechanical strength at multiple sites in ovariectomized mice

scientific article

Detection of Isoflavones in Mouse Tibia After Feeding Daidzein

scientific article published on 01 January 2006

Dexamethasone-induced abnormalities in growth and bone metabolism in piglets are partially attenuated by growth hormone with no synergistic effect of insulin-like growth factor-I.

scientific article published in August 1998

Dietary strategies to optimize wound healing after periodontal and dental implant surgery: an evidence-based review.

scientific article published on 05 April 2013

Diethylstilbesterol has gender-specific effects on weight gain and bone development in mice

scientific article published in January 2008

Differential sclerostin and parathyroid hormone response to exercise in boys and men.

scientific article published on 11 September 2015

Dose effect of dexamethasone on protein turnover in piglets

Early exposure to soy isoflavones and effects on reproductive health: a review of human and animal studies

scientific article

Early life exposure to genistein and daidzein disrupts structural development of reproductive organs in female mice

scientific article published in January 2012

Early life exposure to isoflavones adversely affects reproductive health in first but not second generation female CD-1 mice

scientific article published on 21 September 2011

Effect of Flaxseed on Bone Metabolism and Menopause

Effect of Prenatal Exposure to Isoflavones on Bone Metabolism in Mice at Adulthood

scientific article published on 01 April 2007

Effect of neonatal exposure to genistein on bone metabolism in mice at adulthood.

scientific article published in January 2007

Effects of plyometric exercise session on markers of bone turnover in boys and young men.

scientific article

Exposure to Flaxseed or Purified Lignan During Lactation Influences Rat Mammary Gland Structures

scientific article published on 01 January 2000

Exposure to flaxseed and its purified lignan reduces bone strength in young but not older male rats.

scientific article

Exposure to flaxseed or its purified lignan during suckling only or continuously does not alter reproductive indices in male and female offspring.

scientific article published on December 2001

Exposure to purified lignan from flaxseed (Linum usitatissimum) alters bone development in female rats.

scientific article

Fat-1 gene modulates the fatty acid composition of femoral and vertebral phospholipids.

scientific article published on August 2010

Femur EPA and DHA are correlated with femur biomechanical strength in young fat-1 mice.

scientific article

Flavonoid intake and bone health.

scientific article published on January 2012

Flaxseed Does Not Enhance the Estrogenic Effect of Low-Dose Estrogen Therapy on Markers of Uterine Health in Ovariectomized Rats

scientific article published on 02 August 2012

Flaxseed and Bone Health in Animal Models of Menopause

article

Flaxseed and soy protein isolate, alone and in combination, differ in their effect on bone mass, biomechanical strength, and uterus in ovariectomized nude mice with MCF-7 human breast tumor xenografts

scientific article published on November 2007

Flaxseed combined with low-dose estrogen therapy preserves bone tissue in ovariectomized rats.

scientific article published in May 2009

Flaxseed does not antagonize the effect of ultra-low-dose estrogen therapy on bone mineral density and biomechanical bone strength in ovariectomized rats

scientific article

Flaxseed enhances the beneficial effect of low-dose estrogen therapy at reducing bone turnover and preserving bone microarchitecture in ovariectomized rats

scientific article published on 16 January 2014

Flaxseed oil and bone development in growing male and female mice.

scientific article

Flaxseed oil and inflammation-associated bone abnormalities in interleukin-10 knockout mice

scientific article

Functional Foods and Bone Health: Where are we at?

article

Genistein alone and in combination with the mammalian lignans enterolactone and enterodiol induce estrogenic effects on bone and uterus in a postmenopausal breast cancer mouse model

scientific article published on 15 February 2006

Growth Hormone and Insulin-like Growth Factor-I Therapy Promote Protein Deposition and Growth in Dexamethasone-treated Piglets

scientific article published on 01 April 1999

Growth and body composition of human milk-fed premature infants provided with extra energy and nutrients early after hospital discharge: 1-year follow-up.

scientific article published in October 2009

Gut microbiota-bone axis

scientific article published on 13 October 2015

High saturated fat diet alters the lipid composition of triacylglycerol and polar lipids in the femur of dam and offspring rats

scientific article published on 29 April 2015

Higher Intakes of Fruits and Vegetables, β-Carotene, Vitamin C, α-Tocopherol, EPA, and DHA Are Positively Associated with Periodontal Healing after Nonsurgical Periodontal Therapy in Nonsmokers but Not in Smokers

scientific article published on 30 September 2015

Higher PLIN5 but not PLIN3 content in isolated skeletal muscle mitochondria following acute in vivo contraction in rat hindlimb

scientific article

Higher intakes of flavonoids are associated with lower salivary IL-1β and maintenance of periodontal health 3-4 years after scaling and root planing

scientific article published on 13 February 2020

Increases in skeletal muscle ATGL and its inhibitor G0S2 following 8 weeks of endurance training in metabolically different rat skeletal muscles

scientific article published on 28 October 2015

Influence of Steep Time on Polyphenol Content and Antioxidant Capacity of Black, Green, Rooibos, and Herbal Teas

article by Michael McAlpine & Wendy E. Ward published 1 July 2016 in Beverages

Influence of high-fat diet from differential dietary sources on bone mineral density, bone strength, and bone fatty acid composition in rats

scientific article published on October 2010

Influence of longitudinal radiation exposure from microcomputed tomography scanning on skeletal muscle function and metabolic activity in female CD-1 mice

scientific article

Interleukin-10 knockout mouse: a model for studying bone metabolism during intestinal inflammation

scientific article

Investigating the role of polyunsaturated fatty acids in bone development using animal models.

scientific article

Investigation of factors that influence pain experienced and the use of pain medication following periodontal surgery.

scientific article published on 16 April 2018

Isoflavone exposure throughout suckling results in improved adult bone health in mice

scientific article published in August 2012

Isoflavones with supplemental calcium provide greater protection against the loss of bone mass and strength after ovariectomy compared to isoflavones alone

scientific article published on October 2003

Lifelong intake of flaxseed or menhaden oil to provide varying n-6 to n-3 PUFA ratios modulate bone microarchitecture during growth, but not after OVX in Sprague-Dawley rats

scientific article published on 29 January 2017

Lignan-rich sesame seed negates the tumor-inhibitory effect of tamoxifen but maintains bone health in a postmenopausal athymic mouse model with estrogen-responsive breast tumors.

scientific article published on January 2008

Long-term vitamin D3 supplementation does not prevent colonic inflammation or modulate bone health in IL-10 knockout mice at young adulthood

scientific article

Longitudinal Use of Micro-computed Tomography Does Not Alter Microarchitecture of the Proximal Tibia in Sham or Ovariectomized Sprague–Dawley Rats

scientific article published on 10 February 2016

Low vitamin D status throughout life results in an inflammatory prone status but does not alter bone mineral or strength in healthy 3-month-old CD-1 male mice

scientific article

Mammary gland morphogenesis is enhanced by exposure to flaxseed or its major lignan during suckling in rats

scientific article published on February 2004

Maternal Dietary Vitamin D Does Not Program Systemic Inflammation and Bone Health in Adult Female Mice Fed an Obesogenic Diet

scientific article published on 26 October 2016

Maternal high fat feeding does not have long-lasting effects on body composition and bone health in female and male Wistar rat offspring at young adulthood

scientific article published on 6 December 2013

Maternal vitamin D beneficially programs metabolic, gut and bone health of mouse male offspring in an obesogenic environment.

scientific article published on 4 October 2016

Maternal Consumption of Hesperidin and Naringin Flavanones Exerts Transient Effects to Tibia Bone Structure in Female CD-1 Offspring

scientific article published on 08 March 2017

Mechanical, biochemical, and dietary determinants of the functional model of bone development of the radius in children and adolescents.

scientific article

Methyl vitamins contribute to obesogenic effects of a high multivitamin gestational diet and epigenetic alterations in hypothalamic feeding pathways in Wistar rat offspring.

scientific article published on 14 January 2015

Mo2018 Vitamin D Deficiency in Utero Through Adulthood Results in an Inflammation-Prone Colonic Gene Expression Profile in Healthy CD-1 Mice While IL-10 Knock-out Mice are Not Responsive

article

Musculoskeletal structure and function in response to the combined effect of an obesogenic diet and age in male C57BL/6J mice.

scientific article published on 26 May 2017

Need to Optimize the Health of Women

article

Neonatal administration of isoflavones attenuates deterioration of bone tissue in female but not male mice

scientific article

Neonatal exposure to daidzein, genistein, or the combination modulates bone development in female CD-1 mice.

scientific article published on 21 January 2009

Nutrition, Growth, Bone Metabolism and the Ontogeny of the GH-IGF-I Axis to Term Corrected Age in Very Low Birth Weight Infants Treated with Dexamethasone in Early Life • 1585

article published in 1998

Nutritional Programming of Bone Structure in Male Offspring by Maternal Consumption of Citrus Flavanones

scientific article published on 18 November 2017

Oral Health

article

Oral Health, Nutritional Choices, and Dental Fear and Anxiety.

scientific article published on 21 January 2017

Osteoporosis

Osteoporosis and Osteoarthritis

Ovariectomy-induced hyperphagia does not modulate bone mineral density or bone strength in rats.

scientific article published in November 2008

PUFAs, Bone Mineral Density, and Fragility Fracture: Findings from Human Studies

scientific article published on 15 March 2016

Patients undergoing periodontal procedures commonly use dietary supplements: A consideration in the design of intervention trials

scientific article published on 21 September 2020

Prevention of bone fragility: the role of diet

Proper Positioning and Restraint of a Rat Hind Limb for Focused High Resolution Imaging of Bone Micro-architecture Using In Vivo Micro-computed Tomography

scientific article published on 22 November 2017

Providing Flaxseed Oil but Not Menhaden Oil Protects against OVX Induced Bone Loss in the Mandible of Sprague-Dawley Rats.

scientific article published on 24 September 2016

REDUCED PROTEIN SYNTHESIS AND GROWTH IN DEXAMETHASONE-TREATED PIGLETS IS ATTENUATED WITH ADJUVANT GROWTH HORMONE±INSULIN-LIKE GROWTH FACTOR-I THERAPY • 1442

Response of Bone Turnover Markers and Cytokines to High-Intensity Low-Impact Exercise

scientific article published on 01 July 2015

Response of Sclerostin and Bone Turnover Markers to High Intensity Interval Exercise in Young Women: Does Impact Matter?

scientific article published on 01 November 2018

Revisiting estrogen: efficacy and safety for postmenopausal bone health

scientific article

Rooibos flavonoids, orientin and luteolin, stimulate mineralization in human osteoblasts through the Wnt pathway

scientific article

Saturation of SERCA's lipid annulus may protect against its thermal inactivation

scientific article published on 27 January 2017

Serum equol, bone mineral density and biomechanical bone strength differ among four mouse strains

scientific article

Skeletal site-specific effects of endurance running on structure and strength of tibia, lumbar vertebrae, and mandible in male Sprague–Dawley rats

scientific article published on 03 February 2016

Soy isoflavones and fatty acids: Effects on bone tissue postovariectomy in mice

scientific article published on 01 July 2007

Supraphysiological Levels of Quercetin Glycosides are Required to Alter Mineralization in Saos2 Cells

scientific article published on 29 April 2016

Synergy of Soy, Flaxseed, Calcium, and Hormone Replacement Therapy in Osteoporosis

Tea and bone health: Findings from human studies, potential mechanisms, and identification of knowledge gaps.

scientific article published on 11 June 2015

The Interplay between Estrogen and Fetal Adrenal Cortex

scientific article published on 28 March 2012

The Relationship Between Polycystic Ovarian Syndrome, Periodontal Disease, and Osteoporosis

scientific article published on 10 September 2020

The ovariectomized rat as a model for studying alveolar bone loss in postmenopausal women

scientific article published on 28 April 2015

Total Polyphenol Content and Antioxidant Capacity of Tea Bags: Comparison of Black, Green, Red Rooibos, Chamomile and Peppermint over Different Steep Times

article by Riley Cleverdon et al published 12 February 2018 in Beverages

Transgenerational Benefits of Soy Isoflavones to Bone Structure in the CD-1 Mouse Model

Understanding Food and Food—Drug Synergy

Use of dietary supplements in patients seeking treatment at a periodontal clinic

scientific article published on 02 April 2013

Vertebrae of developing fat-1 mice have greater strength and lower n-6/n-3 fatty acid ratio.

scientific article published on 23 March 2009

List of works by Wendy E. Ward

A Mouse Model for Studying Nutritional Programming: Effects of Early Life Exposure to Soy Isoflavones on Bone and Reproductive Health

A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood

A western-style diet reduces bone mass and biomechanical bone strength to a greater extent in male compared with female rats during development

Accessibility of 3H-Secoisolariciresinol Diglycoside Lignan Metabolites in Skeletal Tissue of Ovariectomized Rats

Adequate but not supplemental folic acid combined with soy isoflavones during early life improves bone health at adulthood in male mice

Adiponectin is a negative regulator of bone mineral and bone strength in growing mice

Biomechanical bone strength and bone mass in young male and female rats fed a fish oil diet

Bone abnormalities in adolescent leptin-deficient mice

Bone development in growing female mice fed calcium and vitamin D at lower levels than is present in the AIN-93G reference diet.

Bone mass, bone strength, and their relationship in developing CD-1 mice

Bone metabolism and circulating IGF-I and IGFBPs in dexamethasone-treated preterm infants

Bone structure is largely unchanged in growing male CD-1 mice fed lower levels of vitamin D and calcium than in the AIN-93G diet

Bone-specific gene expression patterns and whole bone tissue of female mice are programmed by early life exposure to soy isoflavones and folic acid

Changes in mitochondrial perilipin 3 and perilipin 5 protein content in rat skeletal muscle following endurance training and acute stimulated contraction

Circulating isoflavonoid levels in CD-1 mice: effect of oral versus subcutaneous delivery and frequency of administration

Combination of soy protein and high dietary calcium on bone biomechanics and bone mineral density in ovariectomized rats

Combined high-fat-resveratrol diet and RIP140 knockout mice reveal a novel relationship between elevated bone mitochondrial content and compromised bone microarchitecture, bone mineral mass, and bone strength in the tibia

Comparative Response in Growth and Bone Status to Three Dexamethasone Treatment Regimens in Infant Piglets

Comparison of Two Dexamethasone Treatment Regimens on Outcomes of Growth and Bone Metabolism in Piglets † 1523

Comparison of black, green and rooibos tea on osteoblast activity.

Comparison of ex vivo and in vivo micro-computed tomography of rat tibia at different scanning settings

Conclusion

Daidzein together with high calcium preserve bone mass and biomechanical strength at multiple sites in ovariectomized mice

Detection of Isoflavones in Mouse Tibia After Feeding Daidzein

Dexamethasone-induced abnormalities in growth and bone metabolism in piglets are partially attenuated by growth hormone with no synergistic effect of insulin-like growth factor-I.

Dietary strategies to optimize wound healing after periodontal and dental implant surgery: an evidence-based review.

Diethylstilbesterol has gender-specific effects on weight gain and bone development in mice

Differential sclerostin and parathyroid hormone response to exercise in boys and men.

Dose effect of dexamethasone on protein turnover in piglets

Early exposure to soy isoflavones and effects on reproductive health: a review of human and animal studies

Early life exposure to genistein and daidzein disrupts structural development of reproductive organs in female mice

Early life exposure to isoflavones adversely affects reproductive health in first but not second generation female CD-1 mice

Effect of Flaxseed on Bone Metabolism and Menopause

Effect of Prenatal Exposure to Isoflavones on Bone Metabolism in Mice at Adulthood

Effect of neonatal exposure to genistein on bone metabolism in mice at adulthood.

Effects of plyometric exercise session on markers of bone turnover in boys and young men.

Exposure to Flaxseed or Purified Lignan During Lactation Influences Rat Mammary Gland Structures

Exposure to flaxseed and its purified lignan reduces bone strength in young but not older male rats.

Exposure to flaxseed or its purified lignan during suckling only or continuously does not alter reproductive indices in male and female offspring.

Exposure to purified lignan from flaxseed (Linum usitatissimum) alters bone development in female rats.

Fat-1 gene modulates the fatty acid composition of femoral and vertebral phospholipids.

Femur EPA and DHA are correlated with femur biomechanical strength in young fat-1 mice.

Flavonoid intake and bone health.

Flaxseed Does Not Enhance the Estrogenic Effect of Low-Dose Estrogen Therapy on Markers of Uterine Health in Ovariectomized Rats

Flaxseed and Bone Health in Animal Models of Menopause

Flaxseed and soy protein isolate, alone and in combination, differ in their effect on bone mass, biomechanical strength, and uterus in ovariectomized nude mice with MCF-7 human breast tumor xenografts

Flaxseed combined with low-dose estrogen therapy preserves bone tissue in ovariectomized rats.

Flaxseed does not antagonize the effect of ultra-low-dose estrogen therapy on bone mineral density and biomechanical bone strength in ovariectomized rats

Flaxseed enhances the beneficial effect of low-dose estrogen therapy at reducing bone turnover and preserving bone microarchitecture in ovariectomized rats

Flaxseed oil and bone development in growing male and female mice.

Flaxseed oil and inflammation-associated bone abnormalities in interleukin-10 knockout mice

Functional Foods and Bone Health: Where are we at?

Genistein alone and in combination with the mammalian lignans enterolactone and enterodiol induce estrogenic effects on bone and uterus in a postmenopausal breast cancer mouse model

Growth Hormone and Insulin-like Growth Factor-I Therapy Promote Protein Deposition and Growth in Dexamethasone-treated Piglets

Growth and body composition of human milk-fed premature infants provided with extra energy and nutrients early after hospital discharge: 1-year follow-up.

Gut microbiota-bone axis

High saturated fat diet alters the lipid composition of triacylglycerol and polar lipids in the femur of dam and offspring rats

Higher Intakes of Fruits and Vegetables, β-Carotene, Vitamin C, α-Tocopherol, EPA, and DHA Are Positively Associated with Periodontal Healing after Nonsurgical Periodontal Therapy in Nonsmokers but Not in Smokers

Higher PLIN5 but not PLIN3 content in isolated skeletal muscle mitochondria following acute in vivo contraction in rat hindlimb

Higher intakes of flavonoids are associated with lower salivary IL-1β and maintenance of periodontal health 3-4 years after scaling and root planing

Increases in skeletal muscle ATGL and its inhibitor G0S2 following 8 weeks of endurance training in metabolically different rat skeletal muscles

Influence of Steep Time on Polyphenol Content and Antioxidant Capacity of Black, Green, Rooibos, and Herbal Teas

Influence of high-fat diet from differential dietary sources on bone mineral density, bone strength, and bone fatty acid composition in rats

Influence of longitudinal radiation exposure from microcomputed tomography scanning on skeletal muscle function and metabolic activity in female CD-1 mice

Interleukin-10 knockout mouse: a model for studying bone metabolism during intestinal inflammation

Investigating the role of polyunsaturated fatty acids in bone development using animal models.

Investigation of factors that influence pain experienced and the use of pain medication following periodontal surgery.

Isoflavone exposure throughout suckling results in improved adult bone health in mice

Isoflavones with supplemental calcium provide greater protection against the loss of bone mass and strength after ovariectomy compared to isoflavones alone

Lifelong intake of flaxseed or menhaden oil to provide varying n-6 to n-3 PUFA ratios modulate bone microarchitecture during growth, but not after OVX in Sprague-Dawley rats

Lignan-rich sesame seed negates the tumor-inhibitory effect of tamoxifen but maintains bone health in a postmenopausal athymic mouse model with estrogen-responsive breast tumors.

Long-term vitamin D3 supplementation does not prevent colonic inflammation or modulate bone health in IL-10 knockout mice at young adulthood

Longitudinal Use of Micro-computed Tomography Does Not Alter Microarchitecture of the Proximal Tibia in Sham or Ovariectomized Sprague–Dawley Rats

Low vitamin D status throughout life results in an inflammatory prone status but does not alter bone mineral or strength in healthy 3-month-old CD-1 male mice

Mammary gland morphogenesis is enhanced by exposure to flaxseed or its major lignan during suckling in rats

Maternal Dietary Vitamin D Does Not Program Systemic Inflammation and Bone Health in Adult Female Mice Fed an Obesogenic Diet

Maternal high fat feeding does not have long-lasting effects on body composition and bone health in female and male Wistar rat offspring at young adulthood

Maternal vitamin D beneficially programs metabolic, gut and bone health of mouse male offspring in an obesogenic environment.

Maternal Consumption of Hesperidin and Naringin Flavanones Exerts Transient Effects to Tibia Bone Structure in Female CD-1 Offspring