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List of works by Kenneth J. Broadley

111In-labelled leukocyte migration to the lungs of ovalbumin-sensitized guinea-pigs after aerosol challenge with ovalbumin monitored by gamma scintigraphy

scientific article published in January 1999

A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma

scientific article published on 23 August 2012

A simple, rapid, and sensitive scintillation proximity assay for the determination of levels of guinea-pig interleukin-5 in bronchoalveolar lavage samples

scientific article published in April 1997

A3 receptors mediate rapid inflammatory cell influx into the lungs of sensitized guinea-pigs

scientific article published in June 2001

Actions of Artemisia vulgaris extracts and isolated sesquiterpene lactones against receptors mediating contraction of guinea pig ileum and trachea

article

Activation of beta-adrenoceptors mimics preconditioning of rat-isolated atria and ventricles against ischaemic contractile dysfunction

scientific article published on 29 July 2008

Adenosine is not the sole vasodilator released on exposure of isolated guinea-pig hearts to histamine and isoprenaline

scientific article published on 01 March 1994

Adenosine receptor subtypes in airways responses of sensitized guinea-pigs to inhaled ovalbumin

scientific article published on 7 April 2010

Adenosine receptor subtypes in the airways responses to 5'-adenosine monophosphate inhalation of sensitized guinea-pigs

scientific article

Affinities of full agonists for cardiac beta-adrenoceptors calculated by use of in vitro desensitization

scientific article published on 01 June 1990

Alpha- and beta-adrenoceptor-mediated responses of the guinea-pig ileum and the effects of neuronal uptake inhibition

scientific article published on 01 December 1985

Analysis of the atypical characteristics of adenosine receptors mediating negative inotropic and chronotropic responses of guinea-pig isolated atria and papillary muscles

scientific article published in August 1999

Analysis of the bronchoconstrictor responses to adenosine receptor agonists in sensitized guinea-pig lungs and trachea

scientific article published in December 1996

Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity.

scientific article published on 16 September 2010

Bronchoprotection in conscious guinea pigs by budesonide and the NO‐donating analogue, TPI 1020, alone and combined with tiotropium or formoterol ⬇️

scientific article published on October 1, 2012

Cardiac alpha- and beta-adrenoceptor sensitivity and binding characteristics after chronic reserpine pretreatment

scientific article published on 01 December 1987

Cardiac post-junctional alpha 1- and beta-adrenoceptors: effects of chronic chemical sympathectomy with 6-hydroxydopamine

scientific article published in January 1987

Catecholamine-induced vasodilator metabolite release from guinea-pig hearts is not due to increased myocardial activity

scientific article

Comparative effects of inhaled budesonide and the NO-donating budesonide derivative, NCX 1020, against leukocyte influx and airway hyperreactivity following lipopolysaccharide challenge

scientific article

Contractile responses to adenosine, R-PIA and ovalbumen in passively sensitized guinea-pig isolated airways

scientific article published in November 2002

Coronary and aortic vasoconstriction by cathinone, the active constituent of khat

scientific article published in October 2003

Development of a method for monitoring the migration of 111In-labeled eosinophils and neutrophils to the lungs of anaesthetized guinea pigs by gamma scintigraphy and bronchoalveolar lavage

scientific article

Differences between the vasorelaxant activity of adenosine-receptor agonists on guinea-pig isolated aorta precontracted with noradrenaline or phenylephrine.

scientific article published in October 1999

Early and late bronchoconstrictions, airway hyper-reactivity, leucocyte influx and lung histamine and nitric oxide after inhaled antigen: effects of dexamethasone and rolipram

scientific article

Early and late phase bronchoconstrictions in conscious sensitized guinea-pigs after macro- and microshock inhalation of allergen and associated airway accumulation of leukocytes

scientific article published on 01 June 1996

Effect of phosphodiesterase-5 inhibitor, sildenafil (Viagra), in animal models of airways disease

scientific article published on 3 November 2003

Effect of vagotomy on airway hyperreactivity to endogenously released neurotransmitters at 18-24 h after inhaled antigen

scientific article published on 01 May 1998

Effects of adenosine receptor agonists on guinea-pig isolated working hearts and the role of endothelium and NO.

scientific article

Effects of adenosine receptor agonists on induction of contractions to phenylephrine of guinea-pig aorta mediated via intra- or extracellular calcium

scientific article published in August 1999

Effects of dietary amines on the gut and its vasculature

scientific article published on 19 November 2008

Effects of endogenous adenosine and adenosine receptor agonists on hypoxia-induced myocardial stunning in Guinea-pig atria and papillary muscles

scientific article published in March 2004

Effects of hypoxia on the vasodilator activity of nifedipine and evidence of secondary pharmacological properties

scientific article published on 28 February 2006

Effects of inhibitors of phosphodiesterase, on antigen-induced bronchial hyperreactivity in conscious sensitized guinea-pigs and airway leukocyte infiltration

scientific article published in January 1997

Establishing the phenotype in novel acute and chronic murine models of allergic asthma

scientific article published on 22 February 2008

Functional classification of P1-purinoceptors in guinea-pig left and right atria: anomalous characteristics of antagonism by cyclopentyltheophylline

scientific article published in June 1997

Functional evaluation of the receptors mediating vasoconstriction of rat aorta by trace amines and amphetamines

scientific article published on 9 May 2013

Further characterization of the guinea pig left atrial tension response to histamine by use of selective agonists

scientific article published on 01 May 1981

Goblet cell hyperplasia, airway function, and leukocyte infiltration after chronic lipopolysaccharide exposure in conscious Guinea pigs: effects of rolipram and dexamethasone

scientific article published in August 2002

Human parainfluenza type 3 virus impairs the efficacy of glucocorticoids to limit allergy-induced pulmonary inflammation in guinea-pigs

scientific article published in November 2013

Identification of trace-amine-associated receptors (TAAR) in the rat aorta and their role in vasoconstriction by β-phenylethylamine.

scientific article published on September 2010

In vivo demonstration of alpha-adrenoceptor-mediated positive inotropy in pithed rats: evidence that noradrenaline does not stimulate myocardial alpha-adrenoceptors

scientific article published on 01 February 1999

Increased muscarinic receptor activity of airway smooth muscle isolated from a mouse model of allergic asthma

scientific article published on 25 March 2010

Influence of spasmogen inhalation by guinea pigs upon subsequent demonstration of ovalbumin-induced hyperreactivity in isolated airways tissues

scientific article published in December 1995

Influences, decisions and serendipity: an autobiography.

scientific article published in July 2009

Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation

scientific article published on 16 July 2012

Inhibition of field stimulation-induced contractions of rabbit vas deferens by muscarinic receptor agonists: selectivity of McN-A-343 for M1 receptors

scientific article

Investigation of the mechanism for the relaxation of rat duodenum mediated via M1 muscarinic receptors

scientific article published in July 2006

Khat chewing is a risk factor for acute myocardial infarction: a case-control study

scientific article published in May 2005

Khat chewing, cardiovascular diseases and other internal medical problems: the current situation and directions for future research.

scientific article

Mediators of adenosine- and ovalbumen-induced bronchoconstriction of sensitized guinea-pig isolated airways

scientific article published in September 2002

Nitric oxide in respiratory diseases.

scientific article

Non-specific airway hyperreactivity in isolated respiratory preparations from guinea-pigs sensitized and challenged with ovalbumin

scientific article published in October 1994

Optimisation of the sensitisation conditions for an ovalbumin challenge model of asthma

scientific article published on 6 October 2006

PDE4 inhibition and a corticosteroid in chronically antigen exposed conscious guinea-pigs

scientific article published in April 1998

Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity

scientific article

Protection from myocardial stunning by ischaemia and hypoxia with the adenosine A3 receptor agonist, IB-MECA.

scientific article published in September 2003

Radioligand binding and functional responses of ligands for human recombinant adenosine A(3) receptors

scientific article published in April 2006

Relative resistance of functional beta2-adrenoceptor-mediated smooth muscle responses to in vitro desensitization

scientific article published on 01 March 1999

Resistance to antagonism of atrial P(1) purinoceptor responses in the presence of K(+) channel blockade

scientific article

Role of endothelium in ischaemia-induced myocardial dysfunction of isolated working hearts: cardioprotection by activation of adenosine A(2A) receptors.

scientific article

Signal transduction and modulating pathways in tryptamine-evoked vasopressor responses of the rat isolated perfused mesenteric bed ⬇️

scientific article published on October 30, 2012

Synthesis of 5-hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-ones: selective antagonists of muscarinic (M3) receptors

scientific article published on 18 April 2008

TPI 1020, a novel anti-inflammatory, nitric oxide donating compound, potentiates the bronchodilator effects of salbutamol in conscious guinea-pigs

scientific article published on 8 June 2010

Temporal relationships between leukocytes, IL-5 and IL-8 in guinea pig lungs, plasma cortisol and airway function after antigen challenge

scientific article published in January 1999

The effect of phosphodiesterase inhibitors on guinea-pig cardiac responses to histamine and isoprenaline

scientific article published in April 1980

The influence of antidepressant drugs on akinesia produced in mice by intracisternally administered noradrenaline, dopamine and noradnamine

scientific article published on 01 October 1967

The influence of temperature upon reserpine-induced supersensitivity of guinea-pig isolated atria to isoprenaline and salbutamol

scientific article

The ligand-receptor-G-protein ternary complex as a GTP-synthase. steady-state proton pumping and dose-response relationships for beta -adrenoceptors

scientific article published on 01 July 2000

The potential roles of cytokines, IL-5 and IL-8, and plasma cortisol in the anti-inflammatory actions of phosphodiesterase inhibitors in sensitized guinea-pig airways

scientific article published on 01 October 1997

The roles of alpha- and beta-adrenoceptor stimulation in myocardial ischaemia.

scientific article

The vascular effects of trace amines and amphetamines

scientific article

Towards a thermodynamic definition of efficacy in partial agonism: The thermodynamics of efficacy and ligand proton transfer in a G protein-coupled receptor of the rhodopsin class

scientific article published on 18 August 2010

Uptake and metabolism of histamine in guinea-pig isolated atria and their relationship to the pharmacological responses

scientific article published in January 1980

Vasoconstriction of porcine left anterior descending coronary artery by ecstasy and cathinone is not an indirect sympathomimetic effect

scientific article published on 19 March 2007

Vasoconstrictor and vasodilator responses to tryptamine of rat-isolated perfused mesentery: comparison with tyramine and β-phenylethylamine.

scientific article published on April 2012

beta-Adrenoceptor ligand binding and supersensitivity to isoprenaline of ventricular muscle after chronic reserpine pretreatment

scientific article published on 01 September 1982

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