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List of works by Richard J. Hopkinson

2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2.

scientific article published on 9 March 2018

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.

scientific article published on August 2013

Analysis of JmjC Demethylase-Catalyzed Demethylation Using Geometrically-Constrained Lysine Analogues

scientific article published on 25 November 2015

Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases

scientific article

Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern

scientific article published on 28 October 2019

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants

scientific article published on 01 July 2019

Deciphering Functions of Intracellular Formaldehyde: Linking Cancer and Aldehyde Metabolism

scientific article

Formaldehyde quantification using ampicillin is not selective

scientific article published on 04 December 2019

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides

scientific article published on 06 April 2017

Human UTY(KDM6C) Is a Male-specific N -Methyl Lysyl Demethylase

scientific article

Human histone demethylase KDM6B can catalyse sequential oxidations

scientific article published on 01 July 2018

Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications

scientific article published on 01 July 2020

Integrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1

scientific article published on 10 August 2018

Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition.

scientific article published on 29 November 2017

Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase.

scientific article published in January 2013

Is JmjC oxygenase catalysis limited to demethylation?

scientific article published on 20 June 2013

JMJD5 is a human arginyl C-3 hydroxylase.

scientific article

Lysine-241 has a role in coupling 2OG turnover with substrate oxidation during KDM4-catalysed histone demethylation

scientific article published on 14 February 2018

Mechanisms of human histone and nucleic acid demethylases

scientific article published on 10 October 2012

Mechanistic and structural studies of KDM-catalysed demethylation of histone 1 isotype 4 at lysine 26

scientific article published on 14 September 2018

Metampicillin is a cyclic aminal produced by reaction of ampicillin with formaldehyde

scientific article published on 21 October 2020

Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde

scientific article published in March 2010

NMR analyses on N-hydroxymethylated nucleobases - implications for formaldehyde toxicity and nucleic acid demethylases.

scientific article published in May 2018

Non-competitive cyclic peptides for targeting enzyme-substrate complexes.

scientific article published on 23 April 2018

Optimal translational termination requires C4 lysyl hydroxylation of eRF1.

scientific article published on 30 January 2014

PIP(2)-binding site in Kir channels: definition by multiscale biomolecular simulations.

scientific article published on November 2009

Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.

scientific article

Photoactivable peptides for identifying enzyme–substrate and protein–protein interactions

scientific article published on 13 December 2010

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

scientific article

Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets

scientific article

Publisher Correction: JMJD5 is a human arginyl C-3 hydroxylase.

scientific article published on 23 April 2018

Recent Progress in Histone Demethylase Inhibitors

scientific article published on 28 December 2015

Selective recognition of the di/trimethylammonium motif by an artificial carboxycalixarene receptor

scientific article published on 16 January 2017

Small-molecule-based inhibition of histone demethylation in cells assessed by quantitative mass spectrometry

scientific article

Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway

scientific article

Studies on the Glutathione-Dependent Formaldehyde-Activating Enzyme from Paracoccus denitrificans

scientific article published on 16 December 2015

Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates

scientific article published on December 2014

Studies on the reaction of glutathione and formaldehyde using NMR.

scientific article published on 24 August 2010

Targeting histone lysine demethylases - progress, challenges, and the future

scientific article

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