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List of works by Edward M. Conway

A Nuclear Attack on Thrombosis and Inflammation

scientific article published on 01 February 2016

A genetic Xenopus laevis tadpole model to study lymphangiogenesis

scientific article

A novel 2-stage approach that detects complement activation in patients with antiphospholipid antibody syndrome.

scientific article published on 9 June 2017

Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis

scientific article published on 12 April 2018

Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA.

scientific article published on 29 December 2016

An ultrastructural study of thrombomodulin endocytosis: internalization occurs via clathrin-coated and non-coated pits

scientific article published on June 1, 1992

An unanticipated role for survivin in organ transplant damage

scientific article published on 14 April 2014

Angiogenesis: a link to thrombosis in athero-thrombotic disease.

scientific article

Another angiogenic gene linked to amyotrophic lateral sclerosis

scientific article published on 14 July 2006

Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles.

scientific article published on 28 June 2011

Anticoagulantly active heparin-like molecules from cultured fibroblasts

scientific article published on 01 September 1986

Basic weapons to degrade C3a and C5a

scientific article published on 06 April 2018

Biologically active thrombomodulin is synthesized by adherent synovial fluid cells and is elevated in synovial fluid of patients with rheumatoid arthritis

scientific article published on 01 February 1993

CD248 and its cytoplasmic domain: a therapeutic target for arthritis

scientific article

CD248 facilitates tumor growth via its cytoplasmic domain. ⬇️

scientific article

CD248: Reviewing its Role in Health and Disease ⬇️

scientific article published on March 1, 2012

Characterization of a mouse model for thrombomodulin deficiency

scientific article published on 01 September 2001

Coagulation and innate immune responses: can we view them separately?

scientific article published on 07 July 2009

Complement Activation in Arterial and Venous Thrombosis is Mediated by Plasmin

scientific article published on 6 February 2016

Complement-coagulation connections

scientific article published on 6 March 2018

Cross Talk Pathways Between Coagulation and Inflammation.

scientific article published on April 2016

Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways.

scientific article published in August 2002

Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties

scientific article published on 12 July 2010

Diagnosis of Western Red Cedar Asthma Using a Blood-based Gene Expression Biomarker Panel

scientific article

Essential Role for Survivin in the Proliferative Expansion of Progenitor and Mature B Cells

scientific article published on 25 January 2016

Essential role for survivin in early brain development

scientific journal article

Essential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis.

scientific article published on 29 December 2003

Evaluation of the anti-angiogenic activity of saponins from Maesa lanceolata by different assays

scientific article published on 01 September 2012

Exploring traditional and nontraditional roles for thrombomodulin

scientific article published on 04 June 2018

Gas6 gains entry into the coagulation cascade

scientific article published on 01 January 2013

Growing better blood vessels

scientific article published on 01 November 2001

HUS and the case for complement.

scientific article

Heat shock of vascular endothelial cells induces an up-regulatory transcriptional response of the thrombomodulin gene that is delayed in onset and does not attenuate

scientific article published on 01 September 1994

Heat shock-sensitive expression of calreticulin. In vitro and in vivo up-regulation

scientific article published on 01 July 1995

Hepatic loss of survivin impairs postnatal liver development and promotes expansion of hepatic progenitor cells in mice

scientific article published on 21 October 2013

Hepatocellular carcinoma repression by TNFα-mediated synergistic lethal effect of mitosis defect-induced senescence and cell death sensitization.

scientific article

Hi-Fi SELEX: A High-Fidelity Digital-PCR Based Therapeutic Aptamer Discovery Platform

scientific article published on 28 February 2015

Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin

scientific article

Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils

scientific article

Inhibition of allergic bronchial asthma by thrombomodulin is mediated by dendritic cells

scientific article published on 13 August 2010

Interplay between fibrinolysis and complement: plasmin cleavage of iC3b modulates immune responses

scientific article

Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure

scientific article published on 13 February 2007

Lack of the lectin-like domain of thrombomodulin worsens Shiga toxin-associated hemolytic uremic syndrome in mice

scientific article

Loss of Survivin influences liver regeneration and is associated with impaired Aurora B function.

scientific article

Loss of survivin in neural precursor cells results in impaired long-term potentiation in the dentate gyrus and CA1-region.

scientific article published on 2 November 2012

Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma

scientific article (publication date: 2013)

Lymph makes you fat

scientific article published on 01 October 2005

Macrophage matrix metalloproteinase-12 dampens inflammation and neutrophil influx in arthritis

scientific article published on 9 October 2014

Mice lacking the lectin-like domain of thrombomodulin are protected against melioidosis

scientific article published on March 2014

Modulation of complement activation and amplification on nanoparticle surfaces by glycopolymer conformation and chemistry

scientific article published on 15 August 2014

Monitoring left ventricular dilation in mice with PET.

scientific article

New specs for arteriovenous identity

scientific article

Plasmodium falciparum-infected erythrocytes: a mutational analysis of cytoadherence via murine thrombomodulin

scientific article published on 01 May 1999

Platelets and Complement Cross-Talk in Early Atherogenesis

scientific article published on 06 September 2019

Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor.

scientific article published on 23 June 2016

Polyphosphate suppresses complement via the terminal pathway

scientific article published on 13 December 2013

Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia

scientific article published on 22 November 2016

Polyphosphates and Complement Activation

scientific article published on 04 April 2019

Protective role of the inhibitor of apoptosis protein, survivin, in toxin-induced acute renal failure

scientific article published on 5 September 2007

Reincarnation of ancient links between coagulation and complement.

scientific article published on June 2015

Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype

scientific article

Role of Gas6 in erythropoiesis and anemia in mice

scientific journal article

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

scientific article

Signalling silenced

scientific article published in Nature

Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation

scientific article published on 17 June 2019

Super factor B-gets atypical HUS

scientific article published on 01 September 2009

Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma

scientific article

Survivin mediates renal proximal tubule recovery from AKI.

scientific article published on 15 August 2013

Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1

scientific article

Survivin selectively modulates genes deregulated in human leukemia stem cells.

scientific article

Survivin splice variants regulate the balance between proliferation and cell death

scientific article

Sweeteners for factor H.

scientific article

TGFβ-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells

scientific article

The Clock Is Ticking as the Clot Thickens ⬇️

scientific article published on 01 November 2011

The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech.

scientific article

The amino terminal lectin-like domain of thrombomodulin is required for constitutive endocytosis

scientific article published on 01 January 1997

The elusive factor Xa receptor: failure to detect transcripts that correspond to the published sequence of EPR-1.

scientific article published in July 2000

The lectin like domain of thrombomodulin is involved in the defence against pyelonephritis.

scientific article published on 10 November 2015

The lectin-like domain of thrombomodulin ameliorates diabetic glomerulopathy via complement inhibition

scientific article published on 26 September 2012

The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways

scientific article

The lectin-like domain of thrombomodulin hampers host defence in pneumococcal pneumonia

scientific article published on 30 August 2012

The lectin-like domain of thrombomodulin interferes with complement activation and protects against arthritis.

scientific article published in August 2006

The lectin-like domain of thrombomodulin protects against ischaemia-reperfusion lung injury

scientific article published on 28 May 2008

The thrombomodulin lectin-like domain does not change host responses to tuberculosis

scientific article published on 17 October 2013

The type XIV family of C-type lectin-like domain (CTLD) containing proteins

scientific article published on 01 March 2012

Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway

scientific article published on 16 July 2012

Thrombin: Coagulation's master regulator of innate immunity

scientific article published on 20 August 2019

Thrombomodulin and its role in inflammation.

scientific article published on 31 July 2011

Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain ⬇️

scientific article published on July 25, 2011

Thrombomodulin lacking the cytoplasmic domain efficiently internalizes thrombin via nonclathrin-coated, pit-mediated endocytosis.

scientific article published on February 1994

Thrombomodulin mutations in atypical hemolytic-uremic syndrome

scientific article

Thrombomodulin's lectin-like domain reduces myocardial damage by interfering with HMGB1-mediated TLR2 signalling.

scientific article published on 9 December 2013

Thrombomodulin-protein C-EPCR system: integrated to regulate coagulation and inflammation

scientific article

Tissue factor gene expression in acute myeloblastic leukemia

scientific article published in November 1989

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

scientific article

Tumor necrosis factor enhances expression of tissue factor mRNA in endothelial cells.

scientific article

VEGF inhibitors make blood

scientific article published on 01 July 2006

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