List of works - Hitoshi Nakatogawa

Appetite for ER/nucleus destruction

scientific article published on October 2015

Atg12-Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site

scientific article

Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis

scientific article published in February 2012

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion

scientific article

Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion

scientific article published on 26 October 2020

Author Correction: Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion

scientific article published on 12 November 2020

Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy

scientific article

Autophagy-related protein 8 (Atg8) family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway

scientific article published on 8 July 2010

Autophagy: Close Contact Keeps Out the Uninvited

COPII vesicles contribute to autophagosomal membranes

scientific article published on 20 February 2019

Characterization of a Mutant Form of SecA That Alleviates a SecY Defect at Low Temperature and Shows a Synthetic Defect with SecY Alteration at High Temperature

scientific article published on 01 June 2000

Characterization of yeast Atg proteins

scientific article

Control of SecA and SecM translation by protein secretion

scientific article published on April 2004

Dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy

scientific article published on 4 November 2009

Dynamics and diversity in autophagy mechanisms: lessons from yeast

scientific article (publication date: July 2009)

Eating the ER and the nucleus for survival under starvation conditions

scientific article published on 29 July 2015

Genetic dissection of SecA: suppressor mutations against the secY205 translocase defect

scientific article published on 01 December 2000

Genetically encoded but nonpolypeptide prolyl-tRNA functions in the A site for SecM-mediated ribosomal stall.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hrr25 phosphorylates the autophagic receptor Atg34 to promote vacuolar transport of α-mannosidase under nitrogen starvation conditions

scientific article

Hrr25 triggers selective autophagy-related pathways by phosphorylating receptor proteins

scientific article

Hrr25: an emerging major player in selective autophagy regulation in Saccharomyces cerevisiae

scientific article

Intraribosomal regulation of expression and fate of proteins

scientific article published on January 2004

Lipidation of Atg8: how is substrate specificity determined without a canonical E3 enzyme?

scientific article published on 21 October 2008

Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein

Localization of Atg3 to autophagy-related membranes and its enhancement by the Atg8-family interacting motif to promote expansion of the membranes

scientific article published on 11 February 2015

Mechanisms governing autophagosome biogenesis

scientific article published on 05 May 2020

Membrane morphology is actively transformed by covalent binding of the protein Atg8 to PE-lipids

scientific article (publication date: 2014)

Molecular mechanisms of autophagy in yeast

scientific article published on December 1, 2008

Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7

scientific article published on 11 November 2012

Pex3 confines pexophagy receptor activity of Atg36 to peroxisomes by regulating Hrr25-mediated phosphorylation and proteasomal degradation

scientific article published on 21 September 2020

Phospholipid methylation controls Atg32-mediated mitophagy and Atg8 recycling

scientific article published on 5 October 2015

Physiological pH and acidic phospholipids contribute to substrate specificity in lipidation of Atg8.

scientific article published on 10 June 2008

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

scientific article

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

scientific article published on 07 October 2013

Regulated degradation: controlling the stability of autophagy gene transcripts.

scientific article

Reticulophagy and nucleophagy: New findings and unsolved issues

scientific article

SDS-PAGE Techniques to Study Ubiquitin-Like Conjugation Systems in Yeast Autophagy

SecM facilitates translocase function of SecA by localizing its biosynthesis

scientific article

Secretion monitor, SecM, undergoes self-translation arrest in the cytosol

scientific article

Starved cells eat ribosomes

Structural basis of Atg8 activation by a homodimeric E1, Atg7

scientific article

Structural basis of target recognition by Atg8/LC3 during selective autophagy

scientific article

Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes

scientific article published on 03 July 2020

The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formation

article published in the Proceedings of the National Academy of Sciences of the United States of America

The NMR structure of the autophagy-related protein Atg8

scientific article

The autophagy-related protein kinase Atg1 interacts with the ubiquitin-like protein Atg8 via the Atg8 family interacting motif to facilitate autophagosome formation

scientific article

The functions of the ribosomal tunnel in a birth of proteins

scientific article published in May 2004

The ribosomal exit tunnel functions as a discriminating gate

scientific article

Translation arrest of SecM is essential for the basal and regulated expression of SecA.

scholarly article

Two Independent Mechanisms Down-regulate the Intrinsic SecA ATPase Activity

scientific article published in Journal of Biological Chemistry

Two distinct mechanisms target the autophagy-related E3 complex to the pre-autophagosomal structure

Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy

scientific article published on January 2013

[Mechanisms of membrane biogenesis in autophagy].

scientific article published in November 2007

List of works by Hitoshi Nakatogawa

Appetite for ER/nucleus destruction

Atg12-Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site

Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion

Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion

Author Correction: Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion

Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy

Autophagy-related protein 8 (Atg8) family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway

Autophagy: Close Contact Keeps Out the Uninvited

COPII vesicles contribute to autophagosomal membranes

Characterization of a Mutant Form of SecA That Alleviates a SecY Defect at Low Temperature and Shows a Synthetic Defect with SecY Alteration at High Temperature

Characterization of yeast Atg proteins

Control of SecA and SecM translation by protein secretion

Dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy

Dynamics and diversity in autophagy mechanisms: lessons from yeast

Eating the ER and the nucleus for survival under starvation conditions

Genetic dissection of SecA: suppressor mutations against the secY205 translocase defect

Genetically encoded but nonpolypeptide prolyl-tRNA functions in the A site for SecM-mediated ribosomal stall.

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Hrr25 phosphorylates the autophagic receptor Atg34 to promote vacuolar transport of α-mannosidase under nitrogen starvation conditions

Hrr25 triggers selective autophagy-related pathways by phosphorylating receptor proteins

Hrr25: an emerging major player in selective autophagy regulation in Saccharomyces cerevisiae

Intraribosomal regulation of expression and fate of proteins

Lipidation of Atg8: how is substrate specificity determined without a canonical E3 enzyme?

Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein

Localization of Atg3 to autophagy-related membranes and its enhancement by the Atg8-family interacting motif to promote expansion of the membranes

Mechanisms governing autophagosome biogenesis

Membrane morphology is actively transformed by covalent binding of the protein Atg8 to PE-lipids

Molecular mechanisms of autophagy in yeast

Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7

Pex3 confines pexophagy receptor activity of Atg36 to peroxisomes by regulating Hrr25-mediated phosphorylation and proteasomal degradation

Phospholipid methylation controls Atg32-mediated mitophagy and Atg8 recycling

Physiological pH and acidic phospholipids contribute to substrate specificity in lipidation of Atg8.

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

Regulated degradation: controlling the stability of autophagy gene transcripts.

Reticulophagy and nucleophagy: New findings and unsolved issues

SDS-PAGE Techniques to Study Ubiquitin-Like Conjugation Systems in Yeast Autophagy

SecM facilitates translocase function of SecA by localizing its biosynthesis

Secretion monitor, SecM, undergoes self-translation arrest in the cytosol

Starved cells eat ribosomes

Structural basis of Atg8 activation by a homodimeric E1, Atg7

Structural basis of target recognition by Atg8/LC3 during selective autophagy

Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes

The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formation

The NMR structure of the autophagy-related protein Atg8

The autophagy-related protein kinase Atg1 interacts with the ubiquitin-like protein Atg8 via the Atg8 family interacting motif to facilitate autophagosome formation

The functions of the ribosomal tunnel in a birth of proteins

The ribosomal exit tunnel functions as a discriminating gate

Translation arrest of SecM is essential for the basal and regulated expression of SecA.

Two Independent Mechanisms Down-regulate the Intrinsic SecA ATPase Activity

Two distinct mechanisms target the autophagy-related E3 complex to the pre-autophagosomal structure

Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy

[Mechanisms of membrane biogenesis in autophagy].