List of works - Victor Sánchez-Margalet

A chemiluminescence method to analyze phosphatidylcholine-phospholipase activity in plasma membrane preparations and in intact cells

scientific article published on 01 November 1995

Activated translation signaling in placenta from pregnant women with gestational diabetes mellitus: possible role of leptin.

scientific article

Affinity purification of pancreastatin receptor-Gq/11 protein complex from rat liver membranes

scientific article published on 01 June 2000

Aquaporins and placenta

scientific article published on 08 November 2019

Automated urinalysis combining physicochemical analysis, on-board centrifugation, and digital imaging in one system: A multicenter performance evaluation of the cobas 6500 urine work area

scientific article published on 19 September 2019

Biomarkers of vascular inflammation and subclinical atherosclerosis in the metabolic syndrome

scientific article published in September 2004

Blocking of melatonin synthesis and MT(1) receptor impairs the activation of Jurkat T cells.

scientific article

Breast Cancer Immunology and Immunotherapy: Current Status and Future Perspectives.

scientific article published on 02 December 2016

Characterization of pancreastatin receptor and signaling in rat HTC hepatoma cells

scientific article published on 01 June 2000

Characterization of pancreastatin receptors and signaling in adipocyte membranes

scientific article published on 01 August 1999

Comparison of Citrate Buffer with Sodium Fluoride as Additives in Determining Glycemia.

scientific article published in November 2017

Diabetes mellitus and cardiovascular risk: Update of the recommendations of the Diabetes and Cardiovascular Disease working group of the Spanish Diabetes Society (SED, 2018)

scientific article published on 10 May 2018

Diminished insulin receptors on erythrocyte ghosts in nonobese patients with essential hypertension independent of hyperinsulinemia

scientific article published in July 1994

Educational intervention together with an on-line quality control program achieve recommended analytical goals for bedside blood glucose monitoring in a 1200-bed university hospital

scientific article

Effective treatment of pulmonary tuberculosis restores plasma leptin levels.

scientific article published on October 2013

Elevated plasma total homocysteine levels in hyperinsulinemic obese subjects

scientific article published in February 2002

Elsevier Trophoblast Research Award lecture: Molecular mechanisms underlying estrogen functions in trophoblastic cells--focus on leptin expression.

scientific article

Evaluation of a HbA1c point-of-care analyzer.

scientific article published on 31 March 2015

Evaluation of two HbA1c point-of-care analyzers

scientific article published on 17 February 2011

Expression and immunohistochemical localization of leptin in human periapical granulomas

scientific article published on May 2015

Expression and immunohistochemical localization of leptin receptor in human periapical granuloma.

scientific article

Expression of activation molecules in neutrophils, monocytes and lymphocytes from patients with unstable angina treated with stent implantation.

scientific article published on March 2004

Fasting Glycemia as Screening Tool to Rule-Out Gestational Diabetes in Low-Risk Population

scientific article published on 01 April 2018

G protein G alpha q/11 and G alpha i1,2 are activated by pancreastatin receptors in rat liver: studies with GTP-gamma 35S and azido-GTP-alpha-32P

scientific article published on 01 June 1999

Glucogenolytic and hyperglycemic effect of 33-49 C-terminal fragment of pancreastatin in the rat in vivo

scientific article published on 01 October 1992

Glycated hemoglobin vs. the oral glucose tolerance test for the exclusion of impaired glucose tolerance in high-risk individuals

scientific article published on 17 September 2010

Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect

scientific article published in August 2001

Homocysteine thiolactone inhibits insulin-stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation

scientific article published in February 2005

Human amniotic membrane conditioned medium inhibits proliferation and modulates related microRNAs expression in hepatocarcinoma cells

scientific article published on 02 October 2019

Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68.

scientific article published in September 2001

Human leptin enhances activation and proliferation of human circulating T lymphocytes

scientific article published on 01 January 2000

Human leptin promotes survival of human circulating blood monocytes prone to apoptosis by activation of p42/44 MAPK pathway

scientific article published in December 2002

Hyperhomocysteinemia correlates with insulin resistance and low-grade systemic inflammation in obese prepubertal children.

scientific article published in January 2006

Increased Expression of Aquaporin 9 in Trophoblast From Gestational Diabetic Patients.

scientific article

Increased plasma pancreastatin-like levels in gestational diabetes: correlation with catecholamine levels

scientific article published in November 1998

Insulin activates Gαil,2 protein in rat hepatoma (HTC) cell membranes

scientific article published on 01 January 1999

Insulin and Leptin Signaling in Placenta from Gestational Diabetic Subjects.

scientific article

Insulin enhances leptin expression in human trophoblastic cells.

scientific article published on 25 July 2013

Insulin-like growth factor-1 stimulation of cells induces formation of complexes containing phosphatidylinositol-3-kinase, guanosine triphosphatase-activating protein (GAP), and p62 GAP-associated protein.

scientific article published in January 1995

Involvement of leptin in the molecular physiology of the placenta.

scientific article

Leptin action in normal and pathological pregnancies

scientific article published on 21 November 2017

Leptin and Nutrition in Gestational Diabetes

scientific article published on 02 July 2020

Leptin expression in healthy and inflamed human dental pulp.

scientific article

Leptin is an anti-apoptotic effector in placental cells involving p53 downregulation

scientific article

Leptin promotes HLA-G expression on placental trophoblasts via the MEK/Erk and PI3K signaling pathways.

scientific article

Leptin promotes cell survival and activates Jurkat T lymphocytes by stimulation of mitogen-activated protein kinase.

scientific article published on March 2008

Leptin promotes dentin sialophosphoprotein expression in human dental pulp.

scientific article

Leptin protects placental cells from apoptosis induced by acidic stress

scientific article published on 18 October 2018

Leptin receptor (Ob-R) expression is induced in peripheral blood mononuclear cells by in vitro activation and in vivo in HIV-infected patients.

scientific article

Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.

scientific article published on 28 October 2010

Leptin receptor is up-regulated in inflamed human dental pulp.

scientific article published on 10 October 2013

Leptin reduces apoptosis triggered by high temperature in human placental villous explants: The role of the p53 pathway.

scientific article published on 22 March 2016

Leptin stimulates DMP-1 and DSPP expression in human dental pulp via MAPK 1/3 and PI3K signaling pathways

scientific article published on 20 November 2018

Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells.

scientific article

Leptin upregulates aquaporin 9 expression in human placenta in vitro.

scientific article

MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells.

scientific article

Mechanisms involved in p53 downregulation by leptin in trophoblastic cells.

scientific article published on September 2015

Modulation of insulin receptor signalling by pancreastatin in HTC hepatoma cells.

scientific article

New horizons in breast cancer: the promise of immunotherapy

scientific article published on 18 June 2018

New insights into the role of the immune microenvironment in breast carcinoma.

scientific article published on 03 June 2013

Normal pancreastatin-like and increased post-glucose insulin levels in young offspring of insulin-resistant non-obese essential hypertensive patients

scientific article published on 01 May 1997

Obesity and Breast Cancer: Role of Leptin

scientific article published on 18 July 2019

Oleylethanolamide impairs glucose tolerance and inhibits insulin-stimulated glucose uptake in rat adipocytes through p38 and JNK MAPK pathways

scientific article published on 10 May 2005

Pancreastatin (33-49) enhances the priming effect of glucose in the rat pancreas

scientific article published on 01 July 1993

Pancreastatin action in the liver: dual coupling to different G proteins.

scientific article published on January 1996

Pancreastatin activates beta3 isoform of phospholipase C via G(alpha)11 protein stimulation in rat liver membranes

scientific article published on 01 August 1998

Pancreastatin activates pertussis toxin-sensitive guanylate cyclase and pertussis toxin-insensitive phospholipase C in rat liver membranes.

scientific article

Pancreastatin and its 33-49 C-terminal fragment inhibit glucagon-stimulated insulin in vivo

scientific article published on 01 July 1992

Pancreastatin decreases plasma epinephrine levels in surgical stress in the rat

scientific article published on 01 July 1993

Pancreastatin increases cytosolic Ca2+ in insulin secreting RINm5F cells.

scientific article published on October 1992

Pancreastatin inhibits insulin-stimulated glycogen synthesis but not glycolysis in rat hepatocytes.

scientific article

Pancreastatin modulates insulin signaling in rat adipocytes: mechanisms of cross-talk.

scientific article

Pancreastatin receptor is coupled to a guanosine triphosphate-binding protein of the G(q/11)alpha family in rat liver membranes

scientific article published in February 1998

Pancreastatin, a chromogranin A-derived peptide, inhibits DNA and protein synthesis by producing nitric oxide in HTC rat hepatoma cells.

scientific article published in July 2001

Pancreastatin, a chromogranin A-derived peptide, inhibits leptin and enhances UCP-2 expression in isolated rat adipocytes.

scientific article published on December 2003

Pancreastatin, a chromogranin-A-derived peptide, inhibits insulin-stimulated glycogen synthesis by activating GSK-3 in rat adipocytes.

scientific article

Pancreastatin. Biological effects and mechanisms of action

scientific article published on 01 January 2000

Pancreastatin: further evidence for its consideration as a regulatory peptide.

scientific article published on February 1996

Pancreastatin: multiple actions on human intermediary metabolism in vivo, variation in disease, and naturally occurring functional genetic polymorphism.

scientific article published on 14 June 2005

Placental leptin expression is mediated by NFκB signaling.

scientific article published in February 2018

Plasma pancreastatin-like immunoreactivity correlates with plasma norepinephrine levels in essential hypertension

scientific article published on 01 August 1995

Postprandial triglyceride-rich lipoproteins promote M1/M2 microglia polarization in a fatty-acid-dependent manner

scientific article published on 15 October 2019

Profile of patients triply infected with HIV and the hepatitis B and C viruses in the HAART era.

scientific article published on May 2008

Proliferation and survival of human amniotic epithelial cells during their hepatic differentiation.

scientific article published on 18 January 2018

Protein kinase C activation promotes cell survival in mature lymphocytes prone to apoptosis

scientific article published on 01 February 1994

Purification of pancreastatin receptor from rat liver membranes

scientific article published on 01 January 2003

Receptors for pancreastatin in rat liver membranes: molecular identification and characterization by covalent cross-linking

scientific article published on 01 July 1994

Regulation of leptin expression by 17beta-estradiol in human placental cells involves membrane associated estrogen receptor alpha

scientific article published in April 2012

Regulation of placental leptin expression by cyclic adenosine 5'-monophosphate involves cross talk between protein kinase A and mitogen-activated protein kinase signaling pathways

scientific article published on 19 May 2010

Reprint of: Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin.

scientific article published on 08 October 2010

Review: Leptin gene expression in the placenta--regulation of a key hormone in trophoblast proliferation and survival.

scientific article published on March 2011

Role of Leptin in Inflammation and Vice Versa

scientific article published on 16 August 2020

Role of Sam68 as an adaptor protein in signal transduction

scientific article

Role of Sam68 in post-transcriptional gene regulation.

scientific article published on 28 November 2013

Role of leptin as a link between metabolism and the immune system.

scientific article published on 4 March 2017

Role of leptin in female reproduction

scientific article published on January 2015

Role of leptin in the activation of immune cells.

scientific article published on 23 March 2010

Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor to insulin receptor substrate 1.

scientific article published in April 1995

Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62, and GTPase-activating protein

scientific article

Sam68 Mediates the Activation of Insulin and Leptin Signalling in Breast Cancer Cells

scientific article

Sam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signaling

scientific journal article

Sam68 interacts with IRS1.

scientific article

Sam68 mediates leptin-stimulated growth by modulating leptin receptor signaling in human trophoblastic JEG-3 cells.

scientific article published on 13 June 2011

Screening for Gestational Diabetes Mellitus by Measuring Glycated Hemoglobin Can Reduce the Use of the Glucose Challenge Test

scientific article published on 01 November 2019

Sensitivity of insulin-secreting RIN m5F cells to undergoing apoptosis by the protein kinase C inhibitor staurosporine

scientific article published on 01 November 1993

Solubilization and molecular characterization of active pancreastatin receptors from rat liver membranes

scientific article published on 01 April 1997

Sp1 transcription factor is a modulator of estradiol leptin induction in placental cells

scientific article published on 08 July 2017

Stimulation of glycogen synthesis by insulin requires S6 kinase and phosphatidylinositol-3-kinase in HTC-IR cells

scientific article published on 01 February 2000

The alternative Epac/cAMP pathway and the MAPK pathway mediate hCG induction of leptin in placental cells

scientific article

The expression of Sam68, a protein involved in insulin signal transduction, is enhanced by insulin stimulation.

scientific article

Up-regulation of placental leptin by human chorionic gonadotropin.

scientific article published on 11 September 2008

[Changes in lymphocyte subsets s and treatment with beta interferon in active multiple sclerosis]

scientific article published in December 1998

[Diabetes mellitus and cardiovascular risk: Working group recommendations of Diabetes and Cardiovascular Disease of the Spanish Society of Diabetes (SED, 2015)]

scientific article published on 29 May 2015

[Diabetes mellitus and cardiovascular risk: Working group recommendations of Diabetes and Cardiovascular Disease of the Spanish Society of Diabetes (SED, 2015)]

scientific article published on 29 March 2015

[Vascular expression of endothelial nitric oxide synthase (eNOS) in essential hypertension]

scientific article published on 01 January 2004

eNOS, nNOS, cGMP and protein kinase G mediate the inhibitory effect of pancreastatin, a chromogranin A-derived peptide, on growth and proliferation of hepatoma cells

scientific article published in February 2005

p68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3K

scientific journal article

List of works by Victor Sánchez-Margalet

A chemiluminescence method to analyze phosphatidylcholine-phospholipase activity in plasma membrane preparations and in intact cells

Activated translation signaling in placenta from pregnant women with gestational diabetes mellitus: possible role of leptin.

Affinity purification of pancreastatin receptor-Gq/11 protein complex from rat liver membranes

Aquaporins and placenta

Automated urinalysis combining physicochemical analysis, on-board centrifugation, and digital imaging in one system: A multicenter performance evaluation of the cobas 6500 urine work area

Biomarkers of vascular inflammation and subclinical atherosclerosis in the metabolic syndrome

Blocking of melatonin synthesis and MT(1) receptor impairs the activation of Jurkat T cells.

Breast Cancer Immunology and Immunotherapy: Current Status and Future Perspectives.

Characterization of pancreastatin receptor and signaling in rat HTC hepatoma cells

Characterization of pancreastatin receptors and signaling in adipocyte membranes

Comparison of Citrate Buffer with Sodium Fluoride as Additives in Determining Glycemia.

Diabetes mellitus and cardiovascular risk: Update of the recommendations of the Diabetes and Cardiovascular Disease working group of the Spanish Diabetes Society (SED, 2018)

Diminished insulin receptors on erythrocyte ghosts in nonobese patients with essential hypertension independent of hyperinsulinemia

Educational intervention together with an on-line quality control program achieve recommended analytical goals for bedside blood glucose monitoring in a 1200-bed university hospital

Effective treatment of pulmonary tuberculosis restores plasma leptin levels.

Elevated plasma total homocysteine levels in hyperinsulinemic obese subjects

Elsevier Trophoblast Research Award lecture: Molecular mechanisms underlying estrogen functions in trophoblastic cells--focus on leptin expression.

Evaluation of a HbA1c point-of-care analyzer.

Evaluation of two HbA1c point-of-care analyzers

Expression and immunohistochemical localization of leptin in human periapical granulomas

Expression and immunohistochemical localization of leptin receptor in human periapical granuloma.

Expression of activation molecules in neutrophils, monocytes and lymphocytes from patients with unstable angina treated with stent implantation.

Fasting Glycemia as Screening Tool to Rule-Out Gestational Diabetes in Low-Risk Population

G protein G alpha q/11 and G alpha i1,2 are activated by pancreastatin receptors in rat liver: studies with GTP-gamma 35S and azido-GTP-alpha-32P

Glucogenolytic and hyperglycemic effect of 33-49 C-terminal fragment of pancreastatin in the rat in vivo

Glycated hemoglobin vs. the oral glucose tolerance test for the exclusion of impaired glucose tolerance in high-risk individuals

Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect

Homocysteine thiolactone inhibits insulin-stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation

Human amniotic membrane conditioned medium inhibits proliferation and modulates related microRNAs expression in hepatocarcinoma cells

Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68.

Human leptin enhances activation and proliferation of human circulating T lymphocytes

Human leptin promotes survival of human circulating blood monocytes prone to apoptosis by activation of p42/44 MAPK pathway

Hyperhomocysteinemia correlates with insulin resistance and low-grade systemic inflammation in obese prepubertal children.

Increased Expression of Aquaporin 9 in Trophoblast From Gestational Diabetic Patients.

Increased plasma pancreastatin-like levels in gestational diabetes: correlation with catecholamine levels

Insulin activates Gαil,2 protein in rat hepatoma (HTC) cell membranes

Insulin and Leptin Signaling in Placenta from Gestational Diabetic Subjects.

Insulin enhances leptin expression in human trophoblastic cells.

Insulin-like growth factor-1 stimulation of cells induces formation of complexes containing phosphatidylinositol-3-kinase, guanosine triphosphatase-activating protein (GAP), and p62 GAP-associated protein.

Involvement of leptin in the molecular physiology of the placenta.

Leptin action in normal and pathological pregnancies

Leptin and Nutrition in Gestational Diabetes

Leptin expression in healthy and inflamed human dental pulp.

Leptin is an anti-apoptotic effector in placental cells involving p53 downregulation

Leptin promotes HLA-G expression on placental trophoblasts via the MEK/Erk and PI3K signaling pathways.

Leptin promotes cell survival and activates Jurkat T lymphocytes by stimulation of mitogen-activated protein kinase.

Leptin promotes dentin sialophosphoprotein expression in human dental pulp.

Leptin protects placental cells from apoptosis induced by acidic stress

Leptin receptor (Ob-R) expression is induced in peripheral blood mononuclear cells by in vitro activation and in vivo in HIV-infected patients.

Leptin receptor activation increases Sam68 tyrosine phosphorylation and expression in human trophoblastic cells.

Leptin receptor is up-regulated in inflamed human dental pulp.

Leptin reduces apoptosis triggered by high temperature in human placental villous explants: The role of the p53 pathway.

Leptin stimulates DMP-1 and DSPP expression in human dental pulp via MAPK 1/3 and PI3K signaling pathways

Leptin stimulates protein synthesis-activating translation machinery in human trophoblastic cells.

Leptin upregulates aquaporin 9 expression in human placenta in vitro.

MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells.

Mechanisms involved in p53 downregulation by leptin in trophoblastic cells.

Modulation of insulin receptor signalling by pancreastatin in HTC hepatoma cells.

New horizons in breast cancer: the promise of immunotherapy

New insights into the role of the immune microenvironment in breast carcinoma.

Normal pancreastatin-like and increased post-glucose insulin levels in young offspring of insulin-resistant non-obese essential hypertensive patients

Obesity and Breast Cancer: Role of Leptin

Oleylethanolamide impairs glucose tolerance and inhibits insulin-stimulated glucose uptake in rat adipocytes through p38 and JNK MAPK pathways

Pancreastatin (33-49) enhances the priming effect of glucose in the rat pancreas

Pancreastatin action in the liver: dual coupling to different G proteins.

Pancreastatin activates beta3 isoform of phospholipase C via G(alpha)11 protein stimulation in rat liver membranes

Pancreastatin activates pertussis toxin-sensitive guanylate cyclase and pertussis toxin-insensitive phospholipase C in rat liver membranes.

Pancreastatin and its 33-49 C-terminal fragment inhibit glucagon-stimulated insulin in vivo

Pancreastatin decreases plasma epinephrine levels in surgical stress in the rat

Pancreastatin increases cytosolic Ca2+ in insulin secreting RINm5F cells.

Pancreastatin inhibits insulin-stimulated glycogen synthesis but not glycolysis in rat hepatocytes.

Pancreastatin modulates insulin signaling in rat adipocytes: mechanisms of cross-talk.

Pancreastatin receptor is coupled to a guanosine triphosphate-binding protein of the G(q/11)alpha family in rat liver membranes

Pancreastatin, a chromogranin A-derived peptide, inhibits DNA and protein synthesis by producing nitric oxide in HTC rat hepatoma cells.

Pancreastatin, a chromogranin A-derived peptide, inhibits leptin and enhances UCP-2 expression in isolated rat adipocytes.

Pancreastatin, a chromogranin-A-derived peptide, inhibits insulin-stimulated glycogen synthesis by activating GSK-3 in rat adipocytes.

Pancreastatin. Biological effects and mechanisms of action

Pancreastatin: further evidence for its consideration as a regulatory peptide.

Pancreastatin: multiple actions on human intermediary metabolism in vivo, variation in disease, and naturally occurring functional genetic polymorphism.