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List of works by Chien-chih Chiu

4-(Phenylsulfanyl)butan-2-One Suppresses Melanin Synthesis and Melanosome Maturation In Vitro and In Vivo.

scientific article

4beta-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest ⬇️

scientific article

7-Hydroxydehydronuciferine induces human melanoma death via triggering autophagy and apoptosis

scientific article published on 14 July 2015

A Quinone-Containing Compound Enhances Camptothecin-Induced Apoptosis of Lung Cancer Through Modulating Endogenous ROS and ERK Signaling.

scientific article published on 27 September 2016

A novel cell-penetrating peptide suppresses breast tumorigenesis by inhibiting β-catenin/LEF-1 signaling.

scientific article

A novel role for β2-microglobulin: a precursor of antibacterial chemokine in respiratory epithelial cells.

scientific article

An Acetamide Derivative as a Camptothecin Sensitizer for Human Non-Small-Cell Lung Cancer Cells through Increased Oxidative Stress and JNK Activation.

scientific article published on 24 October 2016

An indolylquinoline derivative promotes apoptosis in human lung cancer cells by impairing mitochondrial functions.

scientific article published on 8 September 2015

Anti-allergic activity of grapeseed extract (GSE) on RBL-2H3 mast cells

Anticancer activity of released doxorubicin from a folate-mediated polyelectrolyte complex.

scientific article

Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction.

scientific article

Antitumor efficacy of doxorubicin released from crosslinked nanoparticulate chondroitin sulfate/chitosan polyelectrolyte complexes.

scientific article

BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft model

scientific article

Bio-functional constituents from the stems of Liriodendron tulipifera.

scientific article

Biological properties of acidic cosmetic water from seawater

scientific article

Brefeldin A reduces anchorage-independent survival, cancer stem cell potential and migration of MDA-MB-231 human breast cancer cells.

scientific article

Brefeldin a effectively inhibits cancer stem cell-like properties and MMP-9 activity in human colorectal cancer Colo 205 cells

scientific article published on 22 August 2013

BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9.

scientific article published on 3 July 2015

C2-Ceramide-Induced Rb-Dominant Senescence-Like Phenotype Leads to Human Breast Cancer MCF-7 Escape from p53-Dependent Cell Death ⬇️

scientific article published on 02 September 2019

CASP3 gene single-nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children

article

Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma.

scientific article published on 31 January 2013

Cardiotoxin III inhibits proliferation and migration of oral cancer cells through MAPK and MMP signaling.

scientific article published on 8 April 2013

Cardiotoxin III suppresses MDA-MB-231 cell metastasis through the inhibition of EGF/EGFR-mediated signaling pathway ⬇️

scientific article published on June 7, 2012

Chemically conjugating polyethylenimine with chondroitin sulfate to promote CD44-mediated endocytosis for gene delivery.

scientific article

Chondroitin sulfate-polyethylenimine copolymer-coated superparamagnetic iron oxide nanoparticles as an efficient magneto-gene carrier for microRNA-encoding plasmid DNA delivery

scientific article published on May 2015

Cisplatin-induced senescence and growth inhibition in human non-small cell lung cancer cells with ectopic transfer of p16INK4a.

scientific article published on January 2007

Combination Therapy of Chloroquine and C₂-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells

scientific article published on 15 March 2019

Combretastatin A-4 derivatives: synthesis and evaluation of 2,4,5-triaryl-1H-imidazoles as potential agents against H1299 (non-small cell lung cancer cell).

scientific article

Contributions of active site residues to cofactor binding and catalysis of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase

scientific article published on 22 October 2009

Cordyceps militaris Reduces Oxidative Stress and Regulates Immune T Cells to Inhibit Metastatic Melanoma Invasion

scientific article published in 2022

Correction: Chon-Kit Chou, et al. The Regulations of Deubiquitinase USP15 and Its Pathophysiological Mechanisms in Diseases. Int. J. Mol. Sci. 2017, 18, 483.

scientific article published on 25 April 2017

Correlation between leucine rich domain and the stability of LRWD1 protein in human NT2/D1 cells.

scientific article published on 13 August 2014

Curcumin Metabolite Tetrahydrocurcumin in the Treatment of Eye Diseases

scientific article published on 28 December 2020

Curcumin Suppresses Phthalate-Induced Metastasis and the Proportion of Cancer Stem Cell (CSC)-like Cells via the Inhibition of AhR/ERK/SK1 Signaling in Hepatocellular Carcinoma.

scientific article published on 20 November 2015

Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis ⬇️

scientific article published on October 11, 2012

Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction

scientific article published on 27 October 2016

DFIQ, a Novel Quinoline Derivative, Shows Anticancer Potential by Inducing Apoptosis and Autophagy in NSCLC Cell and In Vivo Zebrafish Xenograft Models

scientific article published on 25 May 2020

Decreased expression of thrombomodulin is correlated with tumor cell invasiveness and poor prognosis in nonsmall cell lung cancer

scientific article published on October 2010

Direct Binding of Cisplatin to p22phox, an Endoplasmic Reticulum (ER) Membrane Protein, Contributes to Cisplatin Resistance in Oral Squamous Cell Carcinoma (OSCC) Cells

scientific article published on 21 August 2020

Discovery of 2-[2-(5-nitrofuran-2-yl)vinyl]quinoline derivatives as a novel type of antimetastatic agents.

scientific article

Discovery of indeno[1,2-b]quinoxaline derivatives as potential anticancer agents

scientific article published on 24 November 2015

Distinct CPT-induced deaths in lung cancer cells caused by clathrin-mediated internalization of CP micelles

scientific article published on 22 January 2016

Dual-Incision Laparoscopic Surgery for Peritoneal Dialysis Catheter Implantation and Fixation: A Novel, Simple, and Safe Procedure

scientific article published on 09 July 2013

Ectopic expression of herpes simplex virus-thymidine kinase gene in human non-small cell lung cancer cells conferred caspase-activated apoptosis sensitized by ganciclovir

scientific article published in December 2002

Enhancements of skin cell proliferations and migrations via 6-dehydrogingerdione.

scientific article published on 31 January 2013

Ethyl Acetate Extract of cf. Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress

scholarly article by Chon-Kit Chou published in June 2018

Etoposide (VP-16) elicits apoptosis following prolonged G2-M cell arrest in p53-mutated human non-small cell lung cancer cells

scientific article published on 15 December 2004

Etoposide (VP-16) sensitizes p53-deficient human non-small cell lung cancer cells to caspase-7-mediated apoptosis.

scientific article

Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells

scientific article published on 2 October 2018

Folic Acid Linked Chondroitin Sulfate-Polyethyleneimine Copolymer Based Gene Delivery System

article

Golden berry-derived 4β-hydroxywithanolide E for selectively killing oral cancer cells by generating ROS, DNA damage, and apoptotic pathways

scientific article

Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis, and reduced migration ability.

scientific article published on 10 March 2011

Highly potent and specific siRNAs against E6 or E7 genes of HPV16- or HPV18-infected cervical cancers

scientific article

Induction of apoptosis by 11-dehydrosinulariolide via mitochondrial dysregulation and ER stress pathways in human melanoma cells

scientific article

Inhibition of Src activation with cardiotoxin III blocks migration and invasion of MDA-MB-231 cells ⬇️

scientific article published on August 7, 2013

Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability

scientific article published on October 2016

Involvement of p38 mitogen-activated protein kinase in acquired gemcitabine-resistant human urothelial carcinoma sublines

scientific article

Lucidone suppresses hepatitis C virus replication by Nrf2-mediated heme oxygenase-1 induction

scientific article published on 17 December 2012

Magnolol induces apoptosis via caspase-independent pathways in non-small cell lung cancer cells.

scientific article published on 14 August 2013

MicroRNA-21 Mediates the Protective Effect of Cardiomyocyte-Derived Conditioned Medium on Ameliorating Myocardial Infarction in Rats

scientific article published on 19 August 2019

Nuclear receptor subfamily 2 group F member 1a (nr2f1a) is required for vascular development in zebrafish

scientific article

Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints.

scientific article published on December 2010

Orai1/CRACM1 overexpression suppresses cell proliferation via attenuation of the store-operated calcium influx-mediated signalling pathway in A549 lung cancer cells ⬇️

scientific article published on July 14, 2011

Overexpression of Rho GDP-dissociation inhibitor alpha predicts poor survival in oral squamous cell carcinoma.

scientific article published on 4 May 2011

Polygonum cuspidatum extracts as bioactive antioxidaion, anti-tyrosinase, immune stimulation and anticancer agents

scientific article published on 12 October 2014

Pomegranate extract inhibits migration and invasion of oral cancer cells by downregulating matrix metalloproteinase-2/9 and epithelial-mesenchymal transition

scientific article published on 29 January 2020

Preparation of chondroitin sulfate-g-poly(ε-caprolactone) copolymers as a CD44-targeted vehicle for enhanced intracellular uptake

scientific article published on 12 March 2014

Progesterone increases apoptosis and inversely decreases autophagy in human hepatoma HA22T/VGH cells treated with epirubicin

scientific article published on 19 May 2014

Protective Effects of Extracts on UVB-Induced Damage in Human Retinal Pigment Epithelial Cells Accompanied by Attenuating ROS and DNA Damage

scientific article published on 07 November 2018

Protective effect of caffeic acid on paclitaxel induced anti-proliferation and apoptosis of lung cancer cells involves NF-κB pathway

scientific article

Proteomic investigation of anti‐tumor activities exerted by sinularin against A2058 melanoma cells ⬇️

scientific article published on April 1, 2012

Proteomic investigation of the sinulariolide-treated melanoma cells A375: effects on the cell apoptosis through mitochondrial-related pathway and activation of caspase cascade

scientific article

Purified Astaxanthin from Haematococcus pluvialis Promotes Tissue Regeneration by Reducing Oxidative Stress and the Secretion of Collagen In Vitro and In Vivo

scientific article published on 03 August 2020

Quinoline-Based Compound BPIQ Exerts Anti-Proliferative Effects on Human Retinoblastoma Cells via Modulating Intracellular Reactive Oxygen Species

scientific article published on 12 November 2015

Reactive oxygen species mediate Terbufos-induced apoptosis in mouse testicular cell lines via the modulation of cell cycle and pro-apoptotic proteins

scientific article published on 15 September 2015

Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes

scientific article published on 05 February 2019

Reduction of RNA A-to-I editing in Drosophila acclimated to heat shock

scientific article published on 6 April 2013

Reductive amination-assisted quantitation of tamoxifen and its metabolites by liquid phase chromatography tandem mass spectrometry

scientific article published on 11 January 2016

San-Huang-Xie-Xin-Tang extract suppresses hepatitis C virus replication and virus-induced cyclooxygenase-2 expression.

scientific article published on 20 January 2011

Subamolide E from Cinnamomum subavenium induces sub-G1 cell-cycle arrest and caspase-dependent apoptosis and reduces the migration ability of human melanoma cells.

scientific article published on 7 July 2011

Teroxirone inhibited growth of human non-small cell lung cancer cells by activating p53 ⬇️

scientific article published on August 15, 2013

The Aqueous Extract of Prunella vulgaris Suppresses Cell Invasion and Migration in Human Liver Cancer Cells by Attenuating Matrix Metalloproteinases ⬇️

scientific article published on January 1, 2012

The Effect of Bornyl cis-4-Hydroxycinnamate on Melanoma Cell Apoptosis Is Associated with Mitochondrial Dysfunction and Endoplasmic Reticulum Stress

scientific article

The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression.

scientific article

The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling

scientific article published on 07 January 2020

The Potential Role of Krüppel-Like Zinc-Finger Protein Glis3 in Genetic Diseases and Cancers.

scientific article

The Role of Necroptosis in ROS-Mediated Cancer Therapies and Its Promising Applications

scientific article published on 05 August 2020

The antiproliferative and apoptotic effects of sirtinol, a sirtuin inhibitor on human lung cancer cells by modulating Akt/β-catenin-Foxo3a axis

scientific article

The antiproliferative effect of C2-ceramide on lung cancer cells through apoptosis by inhibiting Akt and NFκB.

scientific article published on 06 January 2014

The suppressed proliferation and premature senescence by ganciclovir in p53-mutated human non-small-lung cancer cells acquiring herpes simplex virus-thymidine kinase cDNA.

scientific article published in January 2005

Transcribed pseudogene ψPPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma

scientific article (publication date: April 2013)

Unfolded Protein Response (UPR) in Survival, Dormancy, Immunosuppression, Metastasis, and Treatments of Cancer Cells.

scientific article

diTFPP, a Phenoxyphenol, Sensitizes Hepatocellular Carcinoma Cells to C<sub>2</sub>-Ceramide-Induced Autophagic Stress by Increasing Oxidative Stress and ER Stress Accompanied by LAMP2 Hypoglycosylation

scientific article published on 20 May 2022

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