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List of works by Denis Lafontaine

'View From A Bridge': A New Perspective on Eukaryotic rRNA Base Modification.

scientific article published on October 2015

A 'garbage can' for ribosomes: how eukaryotes degrade their ribosomes

scientific article

A functional interface at the rDNA connects rRNA synthesis, pre-rRNA processing and nucleolar surveillance in budding yeast

scientific article

A multi-scale map of cell structure fusing protein images and interactions

scientific article published on 24 November 2021

A new system for naming ribosomal proteins

scientific article

A single N-methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes

scientific article published in Scientific Reports

AlkAniline-Seq: profiling of m7G and m3C RNA modifications at single nucleotide resolution

scientific article published on 16 November 2018

Birth of a nucleolus: the evolution of nucleolar compartments

scientific article

Birth of the snoRNPs: the evolution of the modification-guide snoRNAs.

scientific article published in October 1998

Cell size and fat content of dietary-restricted Caenorhabditis elegans are regulated by ATX-2, an mTOR repressor

scientific article published on 25 July 2016

Cloning and Characterization of theKlDIM1 Gene fromKluyveromyces lactis Encoding the m26A Dimethylase of the 18S rRNA

scientific article published on June 30, 1997

Controlling the material properties and rRNA processing function of the nucleolus using light

scientific article published on 09 August 2019

DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity

scientific article published on 17 November 2021

Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3.

scientific article

Dim2p, a KH-domain protein required for small ribosomal subunit synthesis

scientific article

Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction

scientific article

Identification of genes that function in the biogenesis and localization of small nucleolar RNAs in Saccharomyces cerevisiae.

scientific article published on 31 March 2008

Identification of sites of 2'-O-methylation vulnerability in human ribosomal RNAs by systematic mapping

scientific article published on 13 September 2017

Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress

scientific article

Is ribosome synthesis controlled by pol I transcription?

scientific article published on 9 January 2007

Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments

scientific article

Mapping the cleavage sites on mammalian pre-rRNAs: where do we stand?

scientific article published on 08 February 2012

Melanoma addiction to the long non-coding RNA SAMMSON.

scientific article published in March 2016

Noncoding RNAs in eukaryotic ribosome biogenesis and function

scientific article published on January 2015

Nop58p is a common component of the box C+D snoRNPs that is required for snoRNA stability

scientific article

Nopp140-chaperoned 2'-O-methylation of small nuclear RNAs in Cajal bodies ensures splicing fidelity

scientific article published on 22 July 2021

Nucleolar structure across evolution: the transition between bi- and tri-compartmentalized nucleoli lies within the class Reptilia

scientific article published on 16 February 2011

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

scientific article published on 19 April 2018

Precursors to the U3 small nucleolar RNA lack small nucleolar RNP proteins but are stabilized by La binding.

scientific article published in August 2000

SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation

scientific article published on 29 October 2018

Screening the budding yeast genome reveals unique factors affecting K2 toxin susceptibility

scientific article

Specialized box C/D snoRNPs act as antisense guides to target RNA base acetylation

scientific article

Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes

scientific article

Synthesis and assembly of the box C+D small nucleolar RNPs

scientific article

Systematic mapping of rRNA 2'-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis

scientific article published on 18 January 2022

TOR regulates the subcellular distribution of DIM2, a KH domain protein required for cotranscriptional ribosome assembly and pre-40S ribosome export

scientific article

The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast.

scientific article

The 18S ribosomal RNA m6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila

scientific article published on 29 April 2020

The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis

scientific article published on 01 August 2019

The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3'-terminal loop of 18 S rRNA is essential in yeast

scientific article

The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase

scientific article

The cell proliferation antigen Ki-67 organises heterochromatin

scientific journal article

The complexity of human ribosome biogenesis revealed by systematic nucleolar screening of Pre-rRNA processing factors

scientific article published in August 2013

The evolutionarily conserved protein Las1 is required for pre-rRNA processing at both ends of ITS2

scientific article

The function and synthesis of ribosomes.

scientific article

The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis

scientific journal article

The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis.

scientific article published on 09 August 2016

The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis.

scientific article

The nuclear poly(A) polymerase and Exosome cofactor Trf5 is recruited cotranscriptionally to nucleolar surveillance

scientific article

The nucleolar phase of signal recognition particle assembly

scientific article published in 2024

The nucleolus as a multiphase liquid condensate

scientific article published on 01 September 2020

The nucleolus: structure/function relationship in RNA metabolism

scientific article

The nucleolus: when 2 became 3.

scientific article published in July 2011

The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent

scientific article published on 13 September 2015

The ribosomal RNA m<sup>5</sup>C methyltransferase NSUN-1 modulates healthspan and oogenesis in <i>Caenorhabditis elegans</i>

scientific article published on 08 December 2020

The small nucle(ol)ar RNA cap trimethyltransferase is required for ribosome synthesis and intact nucleolar morphology

scientific article

Trans-acting factors in yeast pre-rRNA and pre-snoRNA processing.

scientific article published on November 1995

Trm112 is required for Bud23-mediated methylation of the 18S rRNA at position G1575.

scientific article

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function.

scientific article published on 2 December 2016

Use of the iNo score to discriminate normal from altered nucleolar morphology, with applications in basic cell biology and potential in human disease diagnostics

scientific article published on 01 October 2018

Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?

scientific article

Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1

scientific journal article

[<< Catch me if you can >>: how the structural and functional integrity of eukaryotic RNA molecules is monitored by surveillance mechanisms]

scientific article published on 01 March 2010