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List of works by Coen Paulusma

A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes.

scientific article published on January 2012

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

scientific article (publication date: June 1997)

ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes

scientific article published on 29 February 2016

ATP8B1 and ATP11C: Two Lipid Flippases Important for Hepatocyte Function

scientific article published on 27 May 2015

ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity

scientific article published in January 2008

ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization

scientific article

Abcg5/8 independent biliary cholesterol excretion in Atp8b1-deficient mice

scientific article

Activity of the bile salt export pump (ABCB11) is critically dependent on canalicular membrane cholesterol content.

scientific article published on 19 February 2009

Alteration of viral lipid composition by expression of the phospholipid floppase ABCB4 reduces HIV vector infectivity

scientific article published on February 2008

Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport

scientific article published on 01 July 2006

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.

scientific article published on March 1999

Cellular localization and biochemical analysis of mammalian CDC50A, a glycosylated β-subunit for P4 ATPases

scientific article published on 17 January 2012

Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETION

scientific article

Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity

scientific article published on 4 August 2011

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

scientific journal article

Differential effects of progressive familial intrahepatic cholestasis type 1 and benign recurrent intrahepatic cholestasis type 1 mutations on canalicular localization of ATP8B1

scientific article

Diseases of intramembranous lipid transport

scientific article published on 30 June 2006

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

scientific article

FXR-dependent reduction of hepatic steatosis in a bile salt deficient mouse model

scientific article published on 15 February 2014

Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein).

scientific article

Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis

scientific article published on 28 July 2014

Hepatocanalicular transport defects: pathophysiologic mechanisms of rare diseases

scientific article

Intestinal bile salt absorption in Atp8b1 deficient mice

scientific article published on 07 March 2007

Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52.

scientific article published on 9 April 2005

Localization of activin subunits in early murine development determined by subunit-specific antibodies

scientific journal article

MRP2 in cholestasis: Putting down the anchor.

scientific article

Multidrug resistance associated protein 2 mediates transport of prostaglandin E2

scientific journal article

Multiple black hepatocellular adenomas in a male patient

scientific article published on 01 November 2000

Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage.

scientific article published on April 2002

Oral availability of cefadroxil depends on ABCC3 and ABCC4.

scientific article published on 13 December 2011

P4 ATPases - lipid flippases and their role in disease

scientific article published on 27 February 2009

P4 ATPases--the physiological relevance of lipid flipping transporters

scientific article published on 07 May 2010

P4 ATPases: flippases in health and disease

scientific article

Progressive familial intrahepatic cholestasis type 1.

scientific article published on 26 April 2010

Rescue of defective ATP8B1 trafficking by CFTR correctors as a therapeutic strategy for familial intrahepatic cholestasis.

scientific article

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

scientific article

Sodium taurocholate cotransporting polypeptide (SLC10A1) deficiency: conjugated hypercholanemia without a clear clinical phenotype

scientific article published on 25 August 2014

Soluble Adenylyl Cyclase Regulates Bile Salt-Induced Apoptosis in Human Cholangiocytes.

scientific article published on 17 March 2016

Strain background modifies phenotypes in the ATP8B1-deficient mouse

scientific article

The architecture of the human Rad54-DNA complex provides evidence for protein translocation along DNA

scientific article

The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man.

scientific article published on June 1997

The flip side of cardiolipin import

scientific article published on 01 April 2011

The lipid flippase heterodimer ATP8B1-CDC50A is essential for surface expression of the apical sodium-dependent bile acid transporter (SLC10A2/ASBT) in intestinal Caco-2 cells.

scientific article

The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator.

scientific article published on 11 June 2016

The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease

scientific article

Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver

scientific article published on 01 March 2000

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