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List of works by Stephane Angers

A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy

scientific article published on 09 June 2021

A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion

scientific article published on 6 October 2015

A bacterial acetyltransferase destroys plant microtubule networks and blocks secretion

scientific article

A novel assay for measurement of membrane-protein surface expression using a β-lactamase

scientific article published on 5 May 2013

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.

scientific article

A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells

scientific article published on 09 April 2018

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells

scientific article published in September 2017

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

scientific article published on 11 July 2017

An aplysia dopamine1-like receptor: molecular and functional characterization

scientific article published on 29 November 2005

Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.

scientific article published on October 1999

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

scientific article

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates

scientific article

Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells

scientific article published in April 2001

Ca(2+)/calmodulin-dependent protein kinase II interacts with group I metabotropic glutamate and facilitates receptor endocytosis and ERK1/2 signaling: role of β-amyloid

scientific article published on 26 March 2015

Calcium-sensing receptor modulates cell adhesion and migration via integrins

scientific journal article

Constitutive Agonist-independent CCR5 Oligomerization and Antibody-mediated Clustering Occurring at Physiological Levels of Receptors

scientific article published in Journal of Biological Chemistry

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

scientific article published on 24 July 2020

Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)

scholarly article

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

scientific article

Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins

scientific article published on 02 August 2016

Emerging non-canonical functions for heterotrimeric G proteins in cellular signaling ⬇️

scientific article published on June 1, 2013

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay

scientific article published on October 2016

Evasion of p53 and G2/M checkpoints are characteristic of Hh-driven basal cell carcinoma.

scientific article published on 10 June 2013

Functional characterization of a novel serotonin receptor (5-HTap2) expressed in the CNS of Aplysia californica

scientific article published in January 2002

Functional significance of oligomerization of G-protein-coupled receptors.

scientific article

G protein betagamma subunits regulate cell adhesion through Rap1a and its effector Radil

scientific article

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

scientific article published on 21 November 2016

Gli proteins in development and disease

scientific article published on 21 July 2011

Glutamate transporter coupling to Na,K-ATPase.

scientific article published in June 2009

Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling

scientific article

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.

scientific article published on 25 January 2018

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

scientific article published on 25 November 2015

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

scientific article published on 23 September 2019

Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting

scientific article published on 20 May 2004

IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers

scientific article published on 01 February 2020

Identification of Novel Smoothened Ligands Using Structure-Based Docking

scientific article

Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells

scientific article

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression

scientific article

Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation

scientific article published on 28 October 2011

Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1.

scientific article

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

scientific article

Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer

scientific article (publication date: 14 June 2002)

New insights in the regulation of Rab GTPases by G protein-coupled receptors

scientific article published on 9 May 2014

New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening

scientific article

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability

scientific article

Oligomeric size of the m2 muscarinic receptor in live cells as determined by quantitative fluorescence resonance energy transfer

scientific article

PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2.

scientific article

Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants

scientific journal article

Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells

scientific article

Proteomic analyses of protein complexes in the Wnt pathway

scientific article

Proximal events in Wnt signal transduction

scientific article (publication date: July 2009)

Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development

scientific article

Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development.

scientific article published in April 2013

Publisher Correction: A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells

scientific article published on 01 September 2018

Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer

scientific article published on 19 September 2002

Radil controls neutrophil adhesion and motility through β2-integrin activation

scientific article

Recovery of oligomers and cooperativity when monomers of the M2 muscarinic cholinergic receptor are reconstituted into phospholipid vesicles

scientific article published on 7 June 2007

Reply: beyond receptor dimerization

scientific article published on 01 September 2000

Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity

scientific article published on 29 June 2016

SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex

scientific article published on January 2016

Scalable, FACS-Free Genome-Wide Phenotypic Screening

Separating the Anti-Inflammatory and Diabetogenic Effects of Glucocorticoids Through LXRβ Antagonism.

scientific article published on 27 January 2017

Single molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival

scientific article published in 2021

Stepping stone: a cytohesin adaptor for membrane cytoskeleton restraint in the syncytial Drosophila embryo

scientific article

Systematic discovery and classification of human cell line essential genes

article

Systematic protein-protein interaction mapping for clinically relevant human GPCRs

scientific article published on 15 March 2017

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice

scientific article published on 27 August 2019

Tandem affinity purification and identification of heterotrimeric g protein-associated proteins

scientific article

Tandem affinity purification to identify cytosolic and nuclear gβγ-interacting proteins

scientific article published on January 2015

The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS).

scientific article published on February 2002

The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity

scientific article published on 15 June 2015

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

scientific article

The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling

scientific article published on 9 December 2014

The Pseudomonas syringae type III effector HopF2 suppresses Arabidopsis stomatal immunity

scientific article published on 11 December 2014

The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions

scientific article published on 30 May 2013

The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling

scientific article

Ubiquitylation and activation of a Rab GTPase is promoted by a β₂AR-HACE1 complex.

scientific article

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.

scientific article published on 10 February 2016

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

scientific article

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells

scientific article published on 06 March 2019

Wnt signaling in development and tissue homeostasis

article

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

scientific journal article

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.

scientific article published on 4 January 2016

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