List of works - Maria Antonietta Vanoni

A single tyrosine hydroxyl group almost entirely controls the NADPH specificity of Plasmodium falciparum ferredoxin-NADP+ reductase

scientific article published on 30 April 2012

Activation and coupling of the glutaminase and synthase reaction of glutamate synthase is mediated by E1013 of the ferredoxin-dependent enzyme, belonging to loop 4 of the synthase domain.

scientific article published on 21 March 2007

Active site plasticity in D-amino acid oxidase: a crystallographic analysis

scientific article

Cold Denaturation of the HIV-1 Protease Monomer.

scientific article published on 7 February 2017

Correction - Kinetic Isotope Effects on the Oxidation of Reduced Nicotinamide Adenine Dinucleotide Phosphate by the Flavoprotein Methylenetetrahydrofolate Reductase

scientific article published in 1984

Cross-talk and ammonia channeling between active centers in the unexpected domain arrangement of glutamate synthase

scientific article

Crystal structure of D-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2

scientific article

Determination of the midpoint potential of the FAD and FMN flavin cofactors and of the 3Fe-4S cluster of glutamate synthase.

scientific article

Does Negative Hyperconjugation Assist Enzymatic Dehydrogenations?

Energy matters: mitochondrial proteomics for biomedicine

scientific article published on 17 January 2011

Enzymology in Europe and Trends in Enzymology 2008

scientific article published in 2008

First-principles molecular dynamics investigation of the D-amino acid oxidative half-reaction catalyzed by the flavoenzyme D-amino acid oxidase

scientific article

Functional properties of recombinant Azospirillum brasilense glutamate synthase, a complex iron-sulfur flavoprotein

scientific article published on 01 May 2000

Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling

scientific article published on 02 July 2016

Glutamate Synthase: Identification of the NADPH-Binding Site by Site-Directed Mutagenesis†

scientific article published on 01 February 2000

Glutamate synthase: A case-study for in silico drug screening on a complex iron–sulfur flavoenzyme?

article

Glutamate synthase: a complex iron-sulphur flavoprotein.

scientific article published on February 1996

Glutamate synthase: a fascinating pathway from L-glutamine to L-glutamate.

scientific article published on March 2004

Glutamine Synthetase 1 Increases Autophagy Lysosomal Degradation of Mutant Huntingtin Aggregates in Neurons, Ameliorating Motility in a Drosophila Model for Huntington's Disease

scientific article published on 13 January 2020

Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process

scientific article published in April 2005

Human MICAL1: activation by the small GTPase Rab8 and small-angle X-ray scattering studies on the oligomerization state of MICAL1 and its complex with Rab8

scientific article published on 31 October 2018

Human histone demethylase LSD1 reads the histone code

scientific article

Imine Deaminase Activity and Conformational Stability of UK114, the Mammalian Member of the Rid Protein Family Active in Amino Acid Metabolism.

scientific article

Influence of divalent cations on the catalytic properties and secondary structure of unadenylylated glutamine synthetase from Azospirillum brasilense

scientific article published in March 2001

Interdomain Loops and Conformational Changes of Glutamate Synthase as Detected by Limited Proteolysis

scientific article published on 01 December 1994

Key Role of the Adenylate Moiety and Integrity of the Adenylate-Binding Site for the NAD(+)/H Binding to Mitochondrial Apoptosis-Inducing Factor.

scientific article published on 4 November 2015

Kinetic and mechanistic characterization of Mycobacterium tuberculosis glutamyl-tRNA synthetase and determination of its oligomeric structure in solution

scientific article published in March 2009

Kinetic and spectroscopic characterization of the putative monooxygenase domain of human MICAL-1

scientific article

Kinetic isotope effects on the oxidation of reduced nicotinamide adenine dinucleotide phosphate by the flavoprotein methylenetetrahydrofolate reductase

scientific article published in October 1984

L-lactate dehydrogenation in flavocytochrome b2: a first principles molecular dynamics study

scientific article

Limited Proteolysis and X-ray Crystallography Reveal the Origin of Substrate Specificity and of the Rate-Limiting Product Release during Oxidation ofd-Amino Acids Catalyzed by Mammaliand-Amino Acid Oxidase†,‡

article by Maria Antonietta Vanoni et al published May 1997 in Biochemistry

MICAL, the flavoenzyme participating in cytoskeleton dynamics

scientific article published on 27 March 2013

Molecular dynamics simulation of the interaction between the complex iron-sulfur flavoprotein glutamate synthase and its substrates.

scientific article published on November 2004

On the iron-sulfur clusters in the complex redox enzyme dihydropyrimidine dehydrogenase

scientific article published on 01 June 2000

Phenylglyoxal modification of arginines in mammalian D-amino-acid oxidase

scientific article published in September 1987

Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis

scientific article

Properties and catalytic activities of MICAL1, the flavoenzyme involved in cytoskeleton dynamics, and modulation by its CH, LIM and C-terminal domains

scientific article published in February 2016

Properties of the recombinant ferredoxin-dependent glutamate synthase of Synechocystis PCC6803. Comparison with the Azospirillum brasilense NADPH-dependent enzyme and its isolated alpha subunit

scientific article

Purification and properties of d-amino-acid oxidase, an inducible flavoenzyme from Rhodotorula gracilis

Purification of the aldehyde oxidase homolog 1 (AOH1) protein and cloning of the AOH1 and aldehyde oxidase homolog 2 (AOH2) genes. Identification of a novel molybdo-flavoprotein gene cluster on mouse chromosome 1

scientific journal article

Quaternary structure of Azospirillum brasilense NADPH-dependent glutamate synthase in solution as revealed by synchrotron radiation x-ray scattering

scientific article published on 30 May 2003

Reaction of the NAD(P)H:Flavin Oxidoreductase fromEscherichia coliwith NADPH and Riboflavin: Identification of Intermediates†

scientific article published on 01 August 1998

Role of the His57−Glu214 Ionic Couple Located in the Active Site ofMycobacterium tuberculosisFprA†,‡

scholarly article by Andrea Pennati et al published July 2006 in Biochemistry

Stereochemistry of reduction of methylenetetrahydrofolate to methyltetrahydrofolate catalyzed by pig liver methylenetetrahydrofolate reductase

scientific article published in 1990

Structural studies on the subunits of glutamate synthase from Azospirillum brasilense.

scientific article

Structural studies on the synchronization of catalytic centers in glutamate synthase

scientific article

Structure--function studies on the iron-sulfur flavoenzyme glutamate synthase: an unexpectedly complex self-regulated enzyme

scientific article

Structure-function studies of MICAL, the unusual multidomain flavoenzyme involved in actin cytoskeleton dynamics

scientific article

Structure-function studies of glutamate synthases: a class of self-regulated iron-sulfur flavoenzymes essential for nitrogen assimilation

scientific article

Structure-function studies on the complex iron-sulfur flavoprotein glutamate synthase: the key enzyme of ammonia assimilation

scientific article

Synthesis and biological evaluation of new amino acids structurally related to the antitumor agent acivicin

scientific article published on September 2003

The Recombinant α Subunit of Glutamate Synthase: Spectroscopic and Catalytic Properties†

scientific article published in 1998

The active conformation of glutamate synthase and its binding to ferredoxin

scientific article

The complex folding behavior of HIV-1-protease monomer revealed by optical-tweezer single-molecule experiments and molecular dynamics simulations.

scientific article

The overexpression of the 3′ terminal region of the CDC25 gene of Saccharomyces cerevisiae causes growth inhibition and alteration of purine nucleotides pools

article

The pH-Dependent Behavior of Catalytic Activities of Azospirillum brasilense Glutamate Synthase and Iodoacetamide Modification of the Enzyme Provide Evidence for a Catalytic Cys-His Ion Pair

article

The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties

scientific article published on 13 November 2019

The subnanometer resolution structure of the glutamate synthase 1.2-MDa hexamer by cryoelectron microscopy and its oligomerization behavior in solution: functional implications

scientific article

The unexpected structural role of glutamate synthase [4Fe-4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit

scientific article published in April 2005

List of works by Maria Antonietta Vanoni

A single tyrosine hydroxyl group almost entirely controls the NADPH specificity of Plasmodium falciparum ferredoxin-NADP+ reductase

Activation and coupling of the glutaminase and synthase reaction of glutamate synthase is mediated by E1013 of the ferredoxin-dependent enzyme, belonging to loop 4 of the synthase domain.

Active site plasticity in D-amino acid oxidase: a crystallographic analysis

Cold Denaturation of the HIV-1 Protease Monomer.

Correction - Kinetic Isotope Effects on the Oxidation of Reduced Nicotinamide Adenine Dinucleotide Phosphate by the Flavoprotein Methylenetetrahydrofolate Reductase

Cross-talk and ammonia channeling between active centers in the unexpected domain arrangement of glutamate synthase

Crystal structure of D-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2

Determination of the midpoint potential of the FAD and FMN flavin cofactors and of the 3Fe-4S cluster of glutamate synthase.

Does Negative Hyperconjugation Assist Enzymatic Dehydrogenations?

Energy matters: mitochondrial proteomics for biomedicine

Enzymology in Europe and Trends in Enzymology 2008

First-principles molecular dynamics investigation of the D-amino acid oxidative half-reaction catalyzed by the flavoenzyme D-amino acid oxidase

Functional properties of recombinant Azospirillum brasilense glutamate synthase, a complex iron-sulfur flavoprotein

Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling

Glutamate Synthase: Identification of the NADPH-Binding Site by Site-Directed Mutagenesis†

Glutamate synthase: A case-study for in silico drug screening on a complex iron–sulfur flavoenzyme?

Glutamate synthase: a complex iron-sulphur flavoprotein.

Glutamate synthase: a fascinating pathway from L-glutamine to L-glutamate.

Glutamine Synthetase 1 Increases Autophagy Lysosomal Degradation of Mutant Huntingtin Aggregates in Neurons, Ameliorating Motility in a Drosophila Model for Huntington's Disease

Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process

Human MICAL1: activation by the small GTPase Rab8 and small-angle X-ray scattering studies on the oligomerization state of MICAL1 and its complex with Rab8

Human histone demethylase LSD1 reads the histone code

Imine Deaminase Activity and Conformational Stability of UK114, the Mammalian Member of the Rid Protein Family Active in Amino Acid Metabolism.

Influence of divalent cations on the catalytic properties and secondary structure of unadenylylated glutamine synthetase from Azospirillum brasilense

Interdomain Loops and Conformational Changes of Glutamate Synthase as Detected by Limited Proteolysis

Key Role of the Adenylate Moiety and Integrity of the Adenylate-Binding Site for the NAD(+)/H Binding to Mitochondrial Apoptosis-Inducing Factor.

Kinetic and mechanistic characterization of Mycobacterium tuberculosis glutamyl-tRNA synthetase and determination of its oligomeric structure in solution

Kinetic and spectroscopic characterization of the putative monooxygenase domain of human MICAL-1

Kinetic isotope effects on the oxidation of reduced nicotinamide adenine dinucleotide phosphate by the flavoprotein methylenetetrahydrofolate reductase

L-lactate dehydrogenation in flavocytochrome b2: a first principles molecular dynamics study

Limited Proteolysis and X-ray Crystallography Reveal the Origin of Substrate Specificity and of the Rate-Limiting Product Release during Oxidation ofd-Amino Acids Catalyzed by Mammaliand-Amino Acid Oxidase†,‡

MICAL, the flavoenzyme participating in cytoskeleton dynamics

Molecular dynamics simulation of the interaction between the complex iron-sulfur flavoprotein glutamate synthase and its substrates.

On the iron-sulfur clusters in the complex redox enzyme dihydropyrimidine dehydrogenase

Phenylglyoxal modification of arginines in mammalian D-amino-acid oxidase

Plasmodium falciparum ferredoxin-NADP+ reductase His286 plays a dual role in NADP(H) binding and catalysis

Properties and catalytic activities of MICAL1, the flavoenzyme involved in cytoskeleton dynamics, and modulation by its CH, LIM and C-terminal domains

Properties of the recombinant ferredoxin-dependent glutamate synthase of Synechocystis PCC6803. Comparison with the Azospirillum brasilense NADPH-dependent enzyme and its isolated alpha subunit

Purification and properties of d-amino-acid oxidase, an inducible flavoenzyme from Rhodotorula gracilis

Purification of the aldehyde oxidase homolog 1 (AOH1) protein and cloning of the AOH1 and aldehyde oxidase homolog 2 (AOH2) genes. Identification of a novel molybdo-flavoprotein gene cluster on mouse chromosome 1

Quaternary structure of Azospirillum brasilense NADPH-dependent glutamate synthase in solution as revealed by synchrotron radiation x-ray scattering

Reaction of the NAD(P)H:Flavin Oxidoreductase fromEscherichia coliwith NADPH and Riboflavin: Identification of Intermediates†

Role of the His57−Glu214 Ionic Couple Located in the Active Site ofMycobacterium tuberculosisFprA†,‡

Stereochemistry of reduction of methylenetetrahydrofolate to methyltetrahydrofolate catalyzed by pig liver methylenetetrahydrofolate reductase

Structural studies on the subunits of glutamate synthase from Azospirillum brasilense.

Structural studies on the synchronization of catalytic centers in glutamate synthase

Structure--function studies on the iron-sulfur flavoenzyme glutamate synthase: an unexpectedly complex self-regulated enzyme

Structure-function studies of MICAL, the unusual multidomain flavoenzyme involved in actin cytoskeleton dynamics

Structure-function studies of glutamate synthases: a class of self-regulated iron-sulfur flavoenzymes essential for nitrogen assimilation

Structure-function studies on the complex iron-sulfur flavoprotein glutamate synthase: the key enzyme of ammonia assimilation

Synthesis and biological evaluation of new amino acids structurally related to the antitumor agent acivicin

The Recombinant α Subunit of Glutamate Synthase: Spectroscopic and Catalytic Properties†

The active conformation of glutamate synthase and its binding to ferredoxin

The complex folding behavior of HIV-1-protease monomer revealed by optical-tweezer single-molecule experiments and molecular dynamics simulations.

The overexpression of the 3′ terminal region of the CDC25 gene of Saccharomyces cerevisiae causes growth inhibition and alteration of purine nucleotides pools

The pH-Dependent Behavior of Catalytic Activities of Azospirillum brasilense Glutamate Synthase and Iodoacetamide Modification of the Enzyme Provide Evidence for a Catalytic Cys-His Ion Pair

The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties

The subnanometer resolution structure of the glutamate synthase 1.2-MDa hexamer by cryoelectron microscopy and its oligomerization behavior in solution: functional implications

The unexpected structural role of glutamate synthase [4Fe-4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit