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List of works by Luca Regazzoni

A Combined High-Resolution Mass Spectrometric and in silico Approach for the Characterisation of Small Ligands of β2-Microglobulin

scientific article published on 01 July 2010

A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress

scientific article published on 22 October 2018

A carnosine intervention study in overweight human volunteers: bioavailability and reactive carbonyl species sequestering effect

scientific article published on 06 June 2016

A rapid profiling of gallotannins and flavonoids of the aqueous extract of Rhus coriaria L. by flow injection analysis with high-resolution mass spectrometry assisted with database searching.

scientific article

A sandwich ELISA for measuring benzo[a]pyrene-albumin adducts in human plasma.

scientific article

A solid-phase extraction procedure coupled to 1H NMR, with chemometric analysis, to seek reliable markers of the botanical origin of honey

scientific article published on 21 May 2008

A tandem MS precursor-ion scan approach to identify variable covalent modification of albumin Cys34: a new tool for studying vascular carbonylation

scientific article published in November 2008

Adductomics Pipeline for Untargeted Analysis of Modifications to Cys34 of Human Serum Albumin.

scientific article published on 29 September 2016

Advanced glycation end products of beta2-microglobulin in uremic patients as determined by high resolution mass spectrometry

scientific article published on 28 December 2013

Albumin is the main nucleophilic target of human plasma: a protective role against pro-atherogenic electrophilic reactive carbonyl species?

scientific article published on 7 March 2008

An integrated high resolution mass spectrometric and informatics approach for the rapid identification of phenolics in plant extract.

scientific article published on 3 March 2011

Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice.

scientific article published on 10 March 2017

Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome Inhibitors

scientific article published on 17 March 2016

Design, synthesis, ADME properties, and pharmacological activities of β-alanyl-D-histidine (D-carnosine) prodrugs with improved bioavailability

scientific article published in June 2011

Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species

scientific article published in June 2009

Development and validation of a HPLC method for the direct separation of carnosine enantiomers and analogues in dietary supplements

scientific article published on 06 August 2019

Development and validation of a sensitive LC-MS/MS assay for the quantification of anserine in human plasma and urine and its application to pharmacokinetic study

article

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease.

scientific article published on 14 April 2017

Edaravone inhibits protein carbonylation by a direct carbonyl-scavenging mechanism: focus on reactivity, selectivity, and reaction mechanisms

scientific article published in March 2010

En bloc elution of proteomes from combinatorial peptide ligand libraries

scientific article

Enzymatic and non-enzymatic detoxification of 4-hydroxynonenal: Methodological aspects and biological consequences.

scientific article published on February 2017

Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90.

scientific article published on 4 May 2015

Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping

scientific article published on 16 June 2011

Glycyl-histidyl-lysine (GHK) Is a Quencher of α,β-4-Hydroxy-trans-2-nonenal: A Comparison with Carnosine. Insights into the Mechanism of Reaction by Electrospray Ionization Mass Spectrometry,1H NMR, and Computational Techniques

scientific article published on 03 August 2007

Guillain Barré syndrome (GBS): new insights in the molecular mimicry between C. jejuni and human peripheral nerve (HPN) proteins

scientific article published on 10 November 2015

Hemoglobin glutathionylation can occur through cysteine sulfenic acid intermediate: electrospray ionization LTQ-Orbitrap hybrid mass spectrometry studies.

scientific article published on 18 May 2009

Human serum albumin cysteinylation is increased in end stage renal disease patients and reduced by hemodialysis: mass spectrometry studies

scientific article published on 09 January 2013

Imine Deaminase Activity and Conformational Stability of UK114, the Mammalian Member of the Rid Protein Family Active in Amino Acid Metabolism.

scientific article

In Vitro Aging of Human Skin Fibroblasts: Age-Dependent Changes in 4-Hydroxynonenal Metabolism

scientific article published on 11 February 2020

Isotopic labelling for the characterisation of HNE-sequestering agents in plant-based extracts and its application for the identification of anthocyanidins in black rice with giant embryo

scientific article published on 23 July 2018

Les Maîtres de l'Orge: the proteome content of your beer mug.

scientific article

MS methods to study macromolecule-ligand interaction: Applications in drug discovery

scholarly article by Federico Riccardi Sirtori published in July 2018

Mass spectrometric characterization of covalent modification of human serum albumin by 4-hydroxy-trans-2-nonenal

scientific article published on 01 September 2006

Mass spectrometric strategies and their applications for molecular mass determination of recombinant therapeutic proteins.

scientific article

Mass spectrometric strategies for the identification and characterization of human serum albumin covalently adducted by amoxicillin: ex vivo studies

scientific article published on 13 August 2014

New sulfurated derivatives of cinnamic acids and rosmaricine as inhibitors of STAT3 and NF-κB transcription factors.

scientific article

Oxidative damage in human gingival fibroblasts exposed to cigarette smoke.

scientific article

Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes

scientific article published on 28 June 2019

Profiling histidine dipeptides in plasma and urine after ingesting beef, chicken or chicken broth in humans.

scientific article published on 19 April 2009

Protein carbonylation: 2,4-dinitrophenylhydrazine reacts with both aldehydes/ketones and sulfenic acids.

scientific article published on 5 March 2009

Quenching of alpha,beta-unsaturated aldehydes by green tea polyphenols: HPLC-ESI-MS/MS studies

scientific article published on 5 June 2008

Ripe and Raw Pu-Erh Tea: LC-MS Profiling, Antioxidant Capacity and Enzyme Inhibition Activities of Aqueous and Hydro-Alcoholic Extracts

scientific article published on 29 January 2019

Screening of fibrillogenesis inhibitors of β2-microglobulin: integrated strategies by mass spectrometry capillary electrophoresis and in silico simulations

scientific article

Screening of preservatives by HPLC-PDA-ESI/MS: A focus on both allowed and recently forbidden compounds in the new EU cosmetics regulation

scientific article published on 26 March 2016

Separation and characterisation of beta2-microglobulin folding conformers by ion-exchange liquid chromatography and ion-exchange liquid chromatography–mass spectrometry

scientific article published on 10 February 2013

Set-up and application of an analytical approach for the quality control of purified colostrum as food supplement

scientific article published on 8 June 2016

Stressed degradation studies of domiphen bromide by LC-ESI-MS/MS identify a novel promising antimicrobial agent

scientific article published on 30 June 2018

Towards the Inhibition of Protein-Protein Interactions (PPIs) in STAT3: Insights into a New Class of Benzothiadiazole Derivatives

scientific article published on 31 July 2020

Urinary profile of methylprednisolone acetate metabolites in patients following intra-articular and intramuscular administration

scientific article published on 19 February 2011

Using lysine adducts of human serum albumin to investigate the disposition of exogenous formaldehyde in human blood.

scientific article published on 16 January 2017