List of works - Shu Chen

Absence of protease-resistant prion protein in the cerebrospinal fluid of Creutzfeldt-Jakob disease

scientific article published in May 2001

Aggregation and fibrillization of the recombinant human prion protein huPrP90-231.

scientific article

Antibody to DNA detects scrapie but not normal prion protein

scholarly article

Assessing prion infectivity of human urine in sporadic Creutzfeldt-Jakob disease

scientific article published in January 2012

CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease

scientific article

Characterization of the prion protein in human urine

scientific article

Chronic wasting disease of elk and deer and Creutzfeldt-Jakob disease: comparative analysis of the scrapie prion protein ⬇️

scientific article published on 7 December 2005

Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta

scientific article

Creutzfeldt-Jakob disease (CJD) with a mutation at codon 148 of prion protein gene: relationship with sporadic CJD.

scientific article

Cryptic peptides of the kringle domains preferentially bind to disease-associated prion protein.

scientific article published on January 2009

Diagnostic value of skin RT-QuIC in Parkinson's disease: a two-laboratory study

scientific article published on 15 November 2021

Different patterns of truncated prion protein fragments correlate with distinct phenotypes in P102L Gerstmann-Sträussler-Scheinker disease

scientific article

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

scientific article published on 23 July 2009

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans

scientific article published on 06 October 2016

Expression and structural characterization of the recombinant human doppel protein

scientific article (publication date: 7 November 2000)

FadA from Fusobacterium nucleatum utilizes both secreted and nonsecreted forms for functional oligomerization for attachment and invasion of host cells.

scientific article published on 22 June 2007

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: clinical, pathological and molecular features.

scientific article published on January 1995

Genetic influence on the structural variations of the abnormal prion protein

scientific article published on August 2000

Gerstmann-Sträussler-Scheinker: a new phenotype with 'curly' PrP deposits

scientific article published in July 2006

Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease

scientific article

Hereditary Creutzfeldt-Jakob disease and fatal familial insomnia.

scientific article

Identification of novel proteinase K-resistant C-terminal fragments of PrP in Creutzfeldt-Jakob disease

scientific article published on 12 August 2003

Inducible overexpression of wild-type prion protein in the muscles leads to a primary myopathy in transgenic mice

scholarly article

Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function

scientific article published in April 2001

Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease?

scientific article published in July 2004

Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity

scientific article

LRRK2 in Parkinson's disease and dementia with Lewy bodies

scientific article

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

scientific article

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

scientific article

Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease

scientific article

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

scientific article published on 06 March 2008

Leucine-rich repeat kinase 2: relevance to Parkinson's disease

scientific article

Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease

scientific article published on 23 December 2004

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats

scientific article published on 28 March 2008

Novel differences between two human prion strains revealed by two-dimensional gel electrophoresis.

scientific article published on 6 August 2001

Paradoxical role of prion protein aggregates in redox-iron induced toxicity

scientific article

Penicillin sulfone inhibitors of class D beta-lactamases

scientific article

Prion protein functions as a ferrireductase partner for ZIP14 and DMT1.

scientific article published on 8 April 2015

Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine.

scientific article published in December 2004

Regional distribution of protease-resistant prion protein in fatal familial insomnia

scientific article published in July 1995

Regulation of DJ-1 by Glutaredoxin 1 in Vivo: Implications for Parkinson's Disease

scientific article

Selection and characterization of DNA aptamers against PrPSc

scientific article published on 28 March 2011

Skin α-Synuclein Aggregation Seeding Activity as a Novel Biomarker for Parkinson Disease

scientific article published on 28 September 2020

Sporadic and familial CJD: classification and characterisation.

scientific article

Tau gene mutation in familial progressive subcortical gliosis

scientific article published in April 1999

The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity

scientific article

The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules

scientific article published on June 2008

Typing prion isoforms.

scientific article published in March 1997

List of works by Shu Chen

Absence of protease-resistant prion protein in the cerebrospinal fluid of Creutzfeldt-Jakob disease

Aggregation and fibrillization of the recombinant human prion protein huPrP90-231.

Antibody to DNA detects scrapie but not normal prion protein

Assessing prion infectivity of human urine in sporadic Creutzfeldt-Jakob disease

CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease

Characterization of the prion protein in human urine

Chronic wasting disease of elk and deer and Creutzfeldt-Jakob disease: comparative analysis of the scrapie prion protein ⬇️

Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta

Creutzfeldt-Jakob disease (CJD) with a mutation at codon 148 of prion protein gene: relationship with sporadic CJD.

Cryptic peptides of the kringle domains preferentially bind to disease-associated prion protein.

Diagnostic value of skin RT-QuIC in Parkinson's disease: a two-laboratory study

Different patterns of truncated prion protein fragments correlate with distinct phenotypes in P102L Gerstmann-Sträussler-Scheinker disease

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans

Expression and structural characterization of the recombinant human doppel protein

FadA from Fusobacterium nucleatum utilizes both secreted and nonsecreted forms for functional oligomerization for attachment and invasion of host cells.

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: clinical, pathological and molecular features.

Genetic influence on the structural variations of the abnormal prion protein

Gerstmann-Sträussler-Scheinker: a new phenotype with 'curly' PrP deposits

Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease

Hereditary Creutzfeldt-Jakob disease and fatal familial insomnia.

Identification of novel proteinase K-resistant C-terminal fragments of PrP in Creutzfeldt-Jakob disease

Inducible overexpression of wild-type prion protein in the muscles leads to a primary myopathy in transgenic mice

Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function

Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease?

Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity

LRRK2 in Parkinson's disease and dementia with Lewy bodies

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies

Leucine-rich repeat kinase 2: relevance to Parkinson's disease

Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats

Novel differences between two human prion strains revealed by two-dimensional gel electrophoresis.

Paradoxical role of prion protein aggregates in redox-iron induced toxicity

Penicillin sulfone inhibitors of class D beta-lactamases

Prion protein functions as a ferrireductase partner for ZIP14 and DMT1.

Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine.

Regional distribution of protease-resistant prion protein in fatal familial insomnia

Regulation of DJ-1 by Glutaredoxin 1 in Vivo: Implications for Parkinson's Disease

Selection and characterization of DNA aptamers against PrPSc

Skin α-Synuclein Aggregation Seeding Activity as a Novel Biomarker for Parkinson Disease

Sporadic and familial CJD: classification and characterisation.

Tau gene mutation in familial progressive subcortical gliosis

The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity

The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules

Typing prion isoforms.