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List of works by Alan Goldin

A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation

scientific article published on 3 May 2009

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

scientific article

A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities

scientific article published in January 2001

A missense mutation in the sodium channel Scn8a is responsible for cerebellar ataxia in the mouse mutant jolting.

scientific article published in October 1996

A mutation that causes ataxia shifts the voltage-dependence of the Scn8a sodium channel

scientific article published on September 1999

A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel

scientific article published on January 1990

A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction

scientific article

A peptide segment critical for sodium channel inactivation functions as an inactivation gate in a potassium channel

scientific article published on 01 November 1993

A rat brain Na+ channel alpha subunit with novel gating properties

scientific article

A voltage-dependent gating transition induces use-dependent block by tetrodotoxin of rat IIA sodium channels expressed in Xenopus oocytes.

scientific article

A voltage-gated calcium-selective channel encoded by a sodium channel-like gene

scientific article

Accessory subunits and sodium channel inactivation

scientific article published on June 1993

Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities

scientific article

Alternative polyadenylation signals in the 3' non-coding region of a voltage-gated potassium channel gene are major determinants of mRNA isoform expression

scientific article

Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels

scientific article

Amino acid residues required for fast Na(+)-channel inactivation: charge neutralizations and deletions in the III-IV linker

scientific article

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

scientific article

An epilepsy mutation in the sodium channel SCN1A that decreases channel excitability

scientific article

Blockade of neuronal sodium channels by the antiepileptic drugs phenytoin, carbamazepine and sodium valproate

scientific article published on January 1999

Chapter 25 Expression of Ion Channels by Injection of mRNA into Xenopus Oocytes

scientific article published on January 1, 1991

Cloning of herpes simplex virus type 1 sequences representing the whole genome

scientific article

Complex genetic interactions in a mouse model of absence epilepsy.

scientific article published on January 2015

Developmental regulation of sodium channel expression in the rat forebrain.

scientific article published in June 1989

Diversity of mammalian voltage-gated sodium channels.

scientific article

Dopaminergic modulation of sodium current in hippocampal neurons via cAMP-dependent phosphorylation of specific sites in the sodium channel alpha subunit.

scientific article published in October 1997

Effects of bisaramil, a novel class I antiarrhythmic agent, on heart, skeletal muscle and brain Na+ channels

scientific article published in January 1998

Evolution of voltage-gated Na(+) channels

scientific article

Expression and chromosomal localization of a lymphocyte K+ channel gene

scientific article

Expression of herpes simplex virus beta and gamma genes integrated in mammalian cells and their induction by an alpha gene product.

scientific article published on November 1983

Functional analysis of the mouse Scn8a sodium channel.

scientific article published on August 1998

Functional analysis of the rat I sodium channel in xenopus oocytes.

scientific article published on February 1998

Functional effects of two voltage-gated sodium channel mutations that cause generalized epilepsy with febrile seizures plus type 2

scientific article (publication date: October 2001)

Generalized epilepsy with febrile seizures plus type 2 mutation W1204R alters voltage-dependent gating of Na(v)1.1 sodium channels

scientific article (publication date: 2003)

Herpes simplex virus thymidine kinase gene is stably maintained and expressed in cells transformed by protoplast fusion

scientific article published in March 1984

High-efficiency transfer of DNA into eukaryotic cells by protoplast fusion

scientific article published on January 1983

High-frequency transfer of cloned herpes simplex virus type 1 sequences to mammalian cells by protoplast fusion.

scientific article published on August 1981

High-level expression and detection of ion channels in Xenopus oocytes

scientific article

Inactivation of cloned Na channels expressed in Xenopus oocytes

scientific article

Increased neuronal firing in computer simulations of sodium channel mutations that cause generalized epilepsy with febrile seizures plus

scientific article published on 31 December 2003

Interaction between the sodium channel inactivation linker and domain III S4-S5.

scientific article

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

scientific article

International Union of Pharmacology. XXXIX. Compendium of voltage-gated ion channels: sodium channels.

scientific article published on December 2003

Maintenance of Xenopus laevis and oocyte injection

scientific article published on January 1, 1992

Mechanisms of sodium channel inactivation

scientific article

Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes

scientific article

Modulation of voltage-gated K+ channels by the sodium channel β1 subunit

scientific article

Molecular analysis of the Na+ channel blocking actions of the novel class I anti-arrhythmic agent RSD 921

scientific article

Molecular basis of isoform-specific micro-conotoxin block of cardiac, skeletal muscle, and brain Na+ channels

scientific article published on 5 December 2002

Naloxone blockade of sodium currents expressed in Xenopus oocytes.

scientific article published in January 1997

Nomenclature of voltage-gated sodium channels

scientific article (publication date: November 2000)

Novel sodium channel gene mutations in Blattella germanica reduce the sensitivity of expressed channels to deltamethrin

scientific article

Persistence of herpes simplex virus genes in cells of neuronal origin

scientific article

Phosphorylation at a single site in the rat brain sodium channel is necessary and sufficient for current reduction by protein kinase A.

scientific article published on August 1997

Phosphorylation of brain sodium channels in the I--II linker modulates channel function in Xenopus oocytes.

scientific article published in March 1996

Point mutations in IIS4 alter activation and inactivation of rat brain IIA Na channels in Xenopus oocyte macropatches.

scientific article

Potent and use-dependent block of cardiac sodium channels by U-50,488H, a benzeneacetamide kappa opioid receptor agonist

scientific article

Potentiation of rat brain sodium channel currents by PKA in Xenopus oocytes involves the I-II linker.

scientific article published on April 2000

Preparation of RNA for injection into Xenopus oocytes

scientific article published in January 1992

Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel

scientific article (publication date: 8 May 1992)

Protein kinase A phosphorylation enhances sodium channel currents in Xenopus oocytes

scientific article published on September 1992

Reply

scientific article published in January 2000

Resurgence of sodium channel research

scientific article

Role of the amino and carboxy termini in isoform-specific sodium channel variation

scientific article published on 19 June 2008

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance

scientific article

Role of the terminal domains in sodium channel localization.

scientific article published on 24 May 2009

Semliki Forest virus vectors with mutations in the nonstructural protein 2 gene permit extended superinfection of neuronal and non-neuronal cells.

scientific article published on August 2007

Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels

scientific article published on 21 March 2014

Shaker-related potassium channels in the central medial nucleus of the thalamus are important molecular targets for arousal suppression by volatile general anesthetics

scientific article published on October 2013

Site-directed mutagenesis of the putative pore region of the rat IIA sodium channel.

scientific article published in April 1993

Sodium channel SCN1A and epilepsy: mutations and mechanisms

scientific article published on September 2010

Sodium channel activation gating is affected by substitutions of voltage sensor positive charges in all four domains

scientific article

Sodium channel blocking and antiarrhythmic actions of the novel arylpiperazine rsd992.

scientific article published in July 2002

Sodium channel carboxyl-terminal residue regulates fast inactivation

scientific article

Sodium channel inactivation is altered by substitution of voltage sensor positive charges

scientific article

Spiradoline, a kappa opioid receptor agonist, produces tonic- and use-dependent block of sodium channels expressed in Xenopus oocytes

scientific article

Stable induction of a 51K cellular protein in neuronal cells surviving herpes simplex virus type 1 infection

scientific article

Substitutions in the domain III voltage-sensing module enhance the sensitivity of an insect sodium channel to a scorpion beta-toxin

scientific article

The adult rat brain beta 1 subunit modifies activation and inactivation gating of multiple sodium channel alpha subunits.

scientific article published in July 1994

The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant

scientific article

Time- and voltage-dependent block of sodium channels expressed in Xenopus oocytes by RSD 921, a novel class I antiarrhythmic drug.

scientific article

Tissue-specific expression of the RI and RII sodium channel subtypes

scientific article

Topology of the Shaker potassium channel probed with hydrophilic epitope insertions

scientific article

Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45

scientific article published on March 1984

U-50,488H, a kappa opioid receptor agonist, is a more potent blocker of cardiac sodium channels than lidocaine.

scientific article

Use-dependent potentiation of the Nav1.6 sodium channel

scientific article

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