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List of works by Leah Young

DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts

scientific journal article

DNA mismatch repair proteins promote apoptosis and suppress tumorigenesis in response to UVB irradiation: an in vivo study

scientific journal article

Defining the DNA mismatch repair-dependent apoptotic pathway in primary cells: evidence for p53-independence and involvement of centrosomal caspase 2

scientific article published on 01 February 2010

Evidence that dysregulated DNA mismatch repair characterizes human nonmelanoma skin cancer.

scientific article published on 26 October 2007

Functional characterization of the kinase activation loop in nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) using tandem affinity purification and liquid chromatography-mass spectrometry.

scientific article

Fusion tyrosine kinase NPM-ALK Deregulates MSH2 and suppresses DNA mismatch repair function novel insights into a potent oncoprotein

scientific article

IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells

scientific article published on 07 May 2009

Investigation of the genes for RET and its ligand complex, GDNF/GFR alpha-I, in small cell lung carcinoma

scientific article published on April 1998

Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation

scientific article published in April 2003

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

scientific article

Serine phosphorylation of NPM-ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potential.

scientific article published on 2 November 2010

Signal transducer and activator of transcription 3 is a transcriptional factor regulating the gene expression of SALL4

scientific article

Studies of phosphoproteomic changes induced by nucleophosmin-anaplastic lymphoma kinase (ALK) highlight deregulation of tumor necrosis factor (TNF)/Fas/TNF-related apoptosis-induced ligand signaling pathway in ALK-positive anaplastic large cell lymp

scientific article published on 14 April 2010

The associated contributions of p53 and the DNA mismatch repair protein Msh6 to spontaneous tumorigenesis

scientific article published on 5 July 2007

The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression

scientific article published on 05 December 2012

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