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List of works by Lucas Bleicher

A new method bridging graph theory and residue co-evolutionary networks for specificity determinant positions detection

scientific article published on 01 May 2019

CONAN: A web application to detect specificity determinants and functional sites by amino acids co-variation network analysis

scientific article published on 11 August 2020

Characterization of an Allosteric Pocket in Zika Virus NS2B-NS3 Protease

scientific article published on 07 February 2022

Closed- and open-state models of human skeletal muscle sodium channel

scientific article published on 30 October 2018

Coevolved Positions Represent Key Functional Properties in the Trypsin-Like Serine Proteases Protein Family

scientific article published on 16 January 2020

Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding

scientific article

Conservation analysis and decomposition of residue correlation networks in the phospholipase A2 superfamily (PLA2s): Insights into the structure-function relationships of snake venom toxins

scientific article published on 30 March 2018

Coq7p relevant residues for protein activity and stability

scientific article published on 21 October 2015

Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia)

scientific article

Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22

scientific article

Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism

scientific article

Crystal structure of yeast hexokinase PI in complex with glucose: A classical "induced fit" example revised

scientific article

Crystallization and preliminary crystallographic analysis of laminarinase from Rhodothermus marinus: a case of pseudomerohedral twinning.

scientific article published in January 2008

Crystallization and preliminary structural analysis of the giant haemoglobin fromGlossoscolex paulistusat 3.2 Å

scientific article published on November 5, 2010

Glutantβase: a database for improving the rational design of glucose-tolerant β-glucosidases

scientific article published on 01 July 2020

Her2p molecular modeling, mutant analysis and intramitochondrial localization.

scientific article published on 11 July 2013

Identification of new bacteria harboring qnrS and aac(6')-Ib/cr and mutations possibly involved in fluoroquinolone resistance in raw sewage and activated sludge samples from a full-scale WWTP.

scientific article

Low-resolution structure and fluorescence anisotropy analysis of protein tyrosine phosphatase eta catalytic domain

scientific article published on 30 March 2007

Mitochondrial ribosome bL34 mutants present diminished translation of cytochrome c oxidase subunits

scientific article published on 21 November 2017

Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from Rhodothermus marinus and molecular dynamics simulations

scientific article

Novel Zn2+-binding Sites in Human Transthyretin: IMPLICATIONS FOR AMYLOIDOGENESIS AND RETINOL-BINDING PROTEIN RECOGNITION

scientific article

Novel arsenic-transforming bacteria and the diversity of their arsenic-related genes and enzymes arising from arsenic-polluted freshwater sediment

scientific article

Orphan nuclear receptor NGFI-B forms dimers with nonclassical interface.

scientific article

PFstats: A Network-Based Open Tool for Protein Family Analysis

scientific article published on 26 February 2018

Residue correlation networks in nuclear receptors reflect functional specialization and the formation of the nematode-specific P-box

scientific article

Sequence, structure and function relationships in flaviviruses as assessed by evolutive aspects of its conserved non-structural protein domains

scientific article published on 10 January 2017

Site-directed mutagenesis and structural modeling of Coq10p indicate the presence of a tunnel for coenzyme Q6 binding

scientific article published on 18 March 2010

Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae

scientific article

Structural and immunological characterization of a new nucleotidyltransferase-like antigen from Paracoccidioides brasiliensis

scientific article published on 17 May 2019

Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms

scientific article

Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function

scientific article published on 19 May 2006

Systematic structural studies of iron superoxide dismutases from human parasites and a statistical coupling analysis of metal binding specificity

scientific article

Thyroxine-binding globulin deficiency due to a novel SERPINA7 mutation: Clinical characterization, analysis of X-chromosome inactivation pattern and protein structural modeling

scientific article published on 04 May 2018

Using amino acid correlation and community detection algorithms to identify functional determinants in protein families

scientific article