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List of works by Silvia Marsoni

A first in human phase I study of the proteasome inhibitor CEP-18770 in patients with advanced solid tumours and multiple myeloma

scientific article published on 08 October 2012

A lesson from vorinostat in pleural mesothelioma

scientific article published on 20 March 2015

A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer

scientific article

A phase I study of the oral platinum agent satraplatin in sequential combination with capecitabine in the treatment of patients with advanced solid malignancies

scientific article published on 27 December 2010

A phase II study of the histone deacetylase inhibitor panobinostat (LBH589) in pretreated patients with small-cell lung cancer

scientific article

A proposal for a new approach to intergroup cancer trials

Actual developments in European regulatory and health technology assessment of new cancer drugs: what does this mean for oncology in Europe?

scientific article published on 10 December 2013

Adjuvant portal-vein infusion of fluorouracil and heparin in colorectal cancer: a randomised trial

scientific article published in The Lancet

An open-label phase 2 study of twice-weekly bortezomib and intermittent pegylated liposomal doxorubicin in patients with ovarian cancer failing platinum-containing regimens

scientific article

Assessment of a HER2 scoring system for colorectal cancer: results from a validation study

scientific article published on 09 October 2015

Cancer drug development in Europe: a selection of new agents under development at the European Drug Development Network.

scientific article

Clinical and pharmacological phase I study with accelerated titration design of a daily times five schedule of BBR3464, a novel cationic triplatinum complex

scientific article published on 01 August 2000

Clinical pharmacokinetics of the new oral camptothecin gimatecan: the inter-patient variability is related to alpha1-acid glycoprotein plasma levels.

scientific article published on 16 December 2009

Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.

scientific article

Concerted escalation of dose and dosing duration in a phase I study of the oral camptothecin gimatecan (ST1481) in patients with advanced solid tumors

scientific article

DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy.

scientific article

Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer

scientific article

Dilemmas in the development of cytoxic drug analogues

scientific article published on January 1, 1992

Dose-Response Relationship in Phase I Clinical Trials: A European Drug Development Network (EDDN) Collaboration Study

article

Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort

scientific article published on 15 August 2016

Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial

scientific article

Early ovarian cancer and the icon trials

scientific article published in January 1992

Early-onset colorectal cancer in young individuals

scientific article published on 22 December 2018

Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial

scientific article published on 22 July 2013

Erratum: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

scientific article published on 01 July 2015

Fluorouracil and folinic acid in colon cancer

scientific article published in The Lancet

Fluorouracil and folinic acid in colon cancer. IMPACT Investigators

Gene expression profiling and prediction of response to hormonal neoadjuvant treatment with anastrozole in surgically resectable breast cancer

scientific article published on 29 April 2010

Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver

Incidence, risk factors and clinical implications of venous thromboembolism in cancer patients treated within the context of phase I studies: the 'SENDO experience'.

scientific article published on 2 November 2011

Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas

scientific article

Integrating liquid biopsies into the management of cancer

scientific article published on 2 March 2017

KRAS mutations affect prognosis of non-small-cell lung cancer patients treated with first-line platinum containing chemotherapy

scientific article published on 15 September 2015

Locoregionally advanced carcinoma of the oropharynx: conventional radiotherapy vs. accelerated hyperfractionated radiotherapy vs. concomitant radiotherapy and chemotherapy--a multicenter randomized trial

scientific article

New Omics Information for Clinical Trial Utility in the Primary Setting

scientific article published on 01 January 2011

Outcome of patients with sarcoma and other mesenchymal tumours participating in phase I trials: a subset analysis of a European Phase I database

scientific article published on 7 March 2014

Patient selection for oncology phase I trials: a multi-institutional study of prognostic factors

scientific article published on 21 February 2012

Pertuzumab and trastuzumab emtansine in patients with HER2-amplified metastatic colorectal cancer: the phase II HERACLES-B trial

scientific article published on 01 September 2020

Pharmacodynamic trial of nimotuzumab in unresectable squamous cell carcinoma of the head and neck: a SENDO Foundation study.

scientific article published on 6 April 2010

Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours.

scientific article published on 4 May 2009

Phase I clinical and pharmacological evaluation of the multi-tyrosine kinase inhibitor SU006668 by chronic oral dosing

scientific article

Phase I clinical study of the novel epothilone B analogue BMS-310705 given on a weekly schedule

scientific article published on 01 September 2007

Phase IB and pharmacological study of the novel taxane BMS-184476 in combination with doxorubicin.

scientific article published in March 2004

Phase IB study of the mTOR inhibitor ridaforolimus with capecitabine.

scientific article published on 20 September 2010

Prediction of early death among patients enrolled in phase I trials: development and validation of a new model based on platelet count and albumin ⬇️

scientific article published on August 21, 2012

Randomized comparison of hexamethylmelamine, adriamycin, cyclophosphamide (hac) vs. cisplatin, adriamycin, cyclophosphamide (pac) in advanced ovarian cancer: long-term results

scientific article published on 01 March 1991

Role of Cetuximab in the Treatment of Patients With NSCLC: Are We Throwing Out the Baby With the Bath Water?

scientific article published on 28 June 2010

Spiromustine: a new agent entering clinical trials

scientific article published on January 1983

Testing epidermal growth factor receptor mutations in patients with non-small-cell lung cancer to choose chemotherapy: the other side of the coin.

scientific article

The genomic landscape of response to EGFR blockade in colorectal cancer.

scientific article published on 30 September 2015

Tiazofurin: a new antitumor agent.

scientific article published on January 1984

Trabectedin for women with ovarian carcinoma after treatment with platinum and taxanes fails.

scientific article

Treating childhood acute lymphoblastic leukaemia (ALL): Summary of ten years' experience in Italy

article

VP16-213 and cyclophosphamide in non oat cell bronchogenic carcinoma

scientific article published on 01 January 1982

Value of KRAS as prognostic or predictive marker in NSCLC: results from the TAILOR trial.

scientific article

Venous thromboembolism is a relevant and underestimated adverse event in cancer patients treated in phase I studies.

scientific article

Vincristine and bleomycin do not interfere with infusional plasma levels of methotrexate

scientific article published on 01 March 1981

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