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List of works by Lin Yuan

A "Double-Locked" and enzyme-activated molecular probe for accurate bioimaging and hepatopathy differentiation

scientific article published on 16 October 2019

A Bioluminescent Probe for Imaging Endogenous Peroxynitrite in Living Cells and Mice.

scientific article published on 22 February 2018

A General Method To Increase Stokes Shift by Introducing Alternating Vibronic Structures

scientific article published on 08 June 2018

A Multisite-Binding Switchable Fluorescent Probe for Monitoring Mitochondrial ATP Level Fluctuation in Live Cells

scientific article published on 16 December 2015

A Selective Near-Infrared Fluorescent Probe for In Vivo Imaging of Thiophenols from a Focused Library.

scientific article

A bioluminescent probe for imaging endogenous hydrogen polysulfides in live cells and a murine model of bacterial infection

scientific article published on 01 April 2019

A cell membrane-anchored fluorescent probe for monitoring carbon monoxide release from living cells

scientific article published on 10 October 2018

A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells.

scientific article

A fast-responsive fluorescent probe for detection of gold ions in water and synthetic products

scientific article published on 17 March 2011

A general strategy for development of a single benzene fluorophore with full-color-tunable, environmentally insensitive, and two-photon solid-state emission

scientific article published on 06 September 2019

A highly selective and sensitive fluorescent probe for Hg(2+) imaging in live cells based on a rhodamine-thioamide-alkyne scaffold.

scientific article published on 8 April 2010

A mitochondria-targeted ratiometric fluorescent probe to monitor endogenously generated sulfur dioxide derivatives in living cells

scientific article

A mitochondrial-targeted prodrug for NIR imaging guided and synergetic NIR photodynamic-chemo cancer therapy.

scientific article published on 14 September 2017

A native-chemical-ligation-mechanism-based ratiometric fluorescent probe for aminothiols

scientific article published on 24 September 2012

A novel ratiometric fluorescent Fe3+ sensor based on a phenanthroimidazole chromophore

scientific article published on 08 January 2009

A ratiometric fluorescent probe for cysteine and homocysteine displaying a large emission shift

scientific article published on 01 December 2008

A ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione based on the drastic distinction in the kinetic profiles.

scientific article published on 18 April 2011

A rational approach to tuning the pKa values of rhodamines for living cell fluorescence imaging

scientific article published on 24 January 2011

A reversible fluorescent Hg2+ chemosensor based on a receptor composed of a thiol atom and an alkene moiety for living cell fluorescence imaging

scientific article published on 21 June 2010

A sensitive and selective fluorescent thiol probe in water based on the conjugate 1,4-addition of thiols to alpha,beta-unsaturated ketones

scientific article published on 01 January 2009

A two-photon fluorescent probe for bio-imaging of formaldehyde in living cells and tissues

scientific article published on 3 May 2016

A unique approach to development of near-infrared fluorescent sensors for in vivo imaging

scientific article published on 07 August 2012

A unique family of rigid analogues of the GFP chromophore with tunable two-photon action cross-sections for biological imaging

scientific article

Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe

scientific article published on 01 January 2020

An ESIPT-Based Ratiometric Fluorescent Probe for Highly Sensitive and Rapid Detection of Sulfite in Living Cells

scientific article published on 07 October 2019

An efficient two-photon fluorescent probe for monitoring mitochondrial singlet oxygen in tissues during photodynamic therapy

scientific article published on 29 September 2016

Analogs of Changsha near-infrared dyes with large Stokes Shifts for bioimaging.

scientific article published on 17 September 2013

Boronic Acid: A Bio-Inspired Strategy To Increase the Sensitivity and Selectivity of Fluorescent NADH Probe

scientific article published on 8 August 2016

Chromophore-Modified Highly Selective Ratiometric Upconversion Nanoprobes for Detection of ONOO- -Related Hepatotoxicity In Vivo

scientific article published on 04 September 2019

Construction of a FRET-based ratiometric fluorescent thiol probe

scientific article published on 12 November 2010

Construction of a near-infrared fluorescence turn-on and ratiometric probe for imaging palladium in living cells

scientific article published on 12 February 2013

Construction of fluorescent probes via protection/deprotection of functional groups: a ratiometric fluorescent probe for Cu2+.

scientific article published in January 2009

Coumarin-caged rosamine probes based on a unique intramolecular carbon-carbon spirocyclization

scientific article published in April 2010

Cu(I)-Catalyzed 6- endo-dig Cyclization of Terminal Alkynes, 2-Bromoaryl Ketones, and Amides toward 1-Naphthylamines: Applications and Photophysical Properties

scientific article published on 05 February 2019

DNA mimics of red fluorescent proteins (RFP) based on G-quadruplex-confined synthetic RFP chromophores.

scientific article

De Novo Design of Chemical Stability Near-Infrared Molecular Probes for High-Fidelity Hepatotoxicity Evaluation In Vivo

scientific article published on 02 April 2019

Design Strategy of Fluorescent Probes for Live Drug-Induced Acute Liver Injury Imaging

scientific article published on 31 December 2020

Design of NIR Chromenylium-Cyanine Fluorophore Library for "Switch-ON" and Ratiometric Detection of Bio-Active Species In Vivo.

scientific article published on 5 January 2016

Detection of analytes in mitochondria without interference from other sites based on an innovative ratiometric fluorophore

scientific article published on 22 May 2018

Development of FRET-based dual-excitation ratiometric fluorescent pH probes and their photocaged derivatives

scientific article published on 27 December 2011

Development of FRET-based ratiometric fluorescent Cu2+ chemodosimeters and the applications for living cell imaging

scientific article published on 27 December 2011

Development of a Highly Selective, Sensitive, and Fast Response Upconversion Luminescent Platform for Hydrogen Sulfide Detection

article

Development of a ratiometric fluorescent sensor for ratiometric imaging of endogenously produced nitric oxide in macrophage cells

scientific article published on 18 July 2011

Development of a reversible fluorescent gold sensor with high selectivity

scientific article published on 25 October 2011

Development of targetable two-photon fluorescent probes to image hypochlorous Acid in mitochondria and lysosome in live cell and inflamed mouse model.

scientific article published on 4 May 2015

Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes

scientific article

Donor and Ring-Fusing Engineering for Far-Red to Near-Infrared Triphenylpyrylium Fluorophores with Enhanced Fluorescence Performance for Sensing and Imaging

scientific article published on 26 April 2019

Double functional group transformations for fluorescent probe construction: a fluorescence turn-on probe for thioureas

scientific article published on 01 June 2010

Engineering a FRET strategy to achieve a ratiometric two-photon fluorescence response with a large emission shift and its application to fluorescence imaging

scientific article

Engineering a Reversible Fluorescent Probe for Real-Time Live-Cell Imaging and Quantification of Mitochondrial ATP

scientific article published on 05 March 2020

Engineering a nanolab for the determination of lysosomal nitric oxide by the rational design of a pH-activatable fluorescent probe.

scientific article published on 30 November 2015

Engineering dithiobenzoic acid lactone-decorated Si-rhodamine as a highly selective near-infrared HOCl fluorescent probe for imaging drug-induced acute nephrotoxicity

scientific article published on 01 September 2019

Engineering of a bioluminescent probe for imaging nitroxyl in live cells and mice

scientific article published on 01 February 2019

Evolving a Unique Red-Emitting Fluorophore with an Optically Tunable Hydroxy Group for Imaging Nitroreductase in Cells, in Tissues, and in Vivo

scientific article published on 06 December 2019

Evolving a novel red-emitting two-photon dye with optically tunable amino group for monitoring the degree of hypoxia during liver fibrosis

scientific article published in 2022

FRET-based mitochondria-targetable dual-excitation ratiometric fluorescent probe for monitoring hydrogen sulfide in living cells.

scientific article published in April 2014

FRET-based small-molecule fluorescent probes: rational design and bioimaging applications.

scientific article published on 18 February 2013

Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging.

scientific article published on January 2013

Fluorescent detection of hypochlorous acid from turn-on to FRET-based ratiometry by a HOCl-mediated cyclization reaction

scientific article published on 23 January 2012

Harvesting Hydrogen Bond Network: Enhance the Anti-Solvatochromic Two-Photon Fluorescence for Cirrhosis Imaging.

scientific article published on 23 April 2018

Hemicyanine-based high resolution ratiometric near-infrared fluorescent probe for monitoring pH changes in vivo

scientific article published on 30 January 2015

High-efficiency in vitro and in vivo detection of Zn2+ by dye-assembled upconversion nanoparticles

scientific article

Imaging of peroxynitrite in drug-induced acute kidney injury with a near-infrared fluorescence and photoacoustic dual-modal molecular probe

scientific article published on 17 June 2020

Investigation of Drug-Induced Hepatotoxicity and Its Remediation Pathway with Reaction-Based Fluorescent Probes.

scientific article published on 19 June 2017

Learning from Artemisinin: Bioinspired Design of a Reaction-Based Fluorescent Probe for the Selective Sensing of Labile Heme in Complex Biosystems

scientific article published on 23 January 2020

Lesson from Nature: Biomimetic Self-Assembling Phthalocyanines for High-Efficient Photothermal Therapy within the Biological Transparent Window

scientific article published on 18 January 2019

Lighting up carbon monoxide: fluorescent probes for monitoring CO in living cells

scientific article published on 13 December 2012

Precipitated Fluorophore-Based Probe for Accurate Detection of Mitochondrial Analytes

scientific article published on 05 January 2021

Ratiometric fluorescent detection of intracellular hydroxyl radicals based on a hybrid coumarin-cyanine platform

scientific article published on 21 September 2010

Rational Engineering of Bioinspired Anthocyanidin Fluorophores with Excellent Two-Photon Properties for Sensing and Imaging.

scientific article published on 9 October 2017

Rational design of a highly reactive ratiometric fluorescent probe for cyanide

scientific article published on 22 June 2011

Selective Visualization of the Endogenous Peroxynitrite in an Inflamed Mouse Model by a Mitochondria-Targetable Two-Photon Ratiometric Fluorescent Probe.

scientific article

Single fluorescent probe responds to H2O2, NO, and H2O2/NO with three different sets of fluorescence signals

scientific article

Surface-initiated atom-transfer radical polymerization of 4-acetoxystyrene for immunosensing.

scientific article

Through-bond energy transfer cassettes with minimal spectral overlap between the donor emission and acceptor absorption: coumarin-rhodamine dyads with large pseudo-Stokes shifts and emission shifts

scientific article published on 01 January 2010

Tumor-acidity activated surface charge conversion of two-photon fluorescent nanoprobe for enhanced cellular uptake and targeted imaging of intracellular hydrogen peroxide

scientific article published on 20 August 2019

Visualization of Endoplasmic Reticulum Aminopeptidase 1 under Different Redox Conditions with a Two-Photon Fluorescent Probe.

scientific article published on 14 June 2017

Visualization of oxidative injury in the mouse kidney using selective superoxide anion fluorescent probes

scientific article published on 13 September 2018

pH stimulus-disaggregated BODIPY: an activated photodynamic/photothermal sensitizer applicable to tumor ablation

scientific article published on 01 February 2020