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List of works by Oliver Rath

A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways.

scientific article published on 22 January 2007

BEZ235 (PIK3/mTOR inhibitor) Overcomes Pazopanib Resistance in Patient-Derived Refractory Soft Tissue Sarcoma Cells

scientific article published on 12 May 2016

Depsidones from Lichens as Natural Product Inhibitors of M-Phase Phosphoprotein 1, a Human Kinesin Required for Cytokinesis

scientific article published on 14 June 2016

Development of Novel Patient-Derived Preclinical Models from Malignant Effusions in Patients with Tyrosine Kinase Inhibitor-Resistant Clear Cell Renal Cell Carcinoma

scientific article published on 15 March 2017

Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine.

scientific article

Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity

scientific article published on 16 September 2013

Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia

scientific article

Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition

scientific article

Investigating dynamics of inhibitory and feedback loops in ERK signalling using power-law models

scientific article published on 18 August 2010

Kinesins and cancer.

scientific article

LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation

scientific article published on 3 November 2015

MAP kinase signalling pathways in cancer

scientific article (publication date: 14 May 2007)

Optimized S -Trityl- l -cysteine-Based Inhibitors of Kinesin Spindle Protein with Potent in Vivo Antitumor Activity in Lung Cancer Xenograft Models

scientific article

Patient-derived cell models as preclinical tools for genome-directed targeted therapy

scientific article

Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway

scientific article published in February 2009

RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility

scientific article published on 23 December 2010

Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β.

scientific article published on 8 February 2011

Regulation of RKIP binding to the N-region of the Raf-1 kinase

scientific article

Regulation of human myoblast differentiation by PEBP4

scientific article

Relocation of Aurora B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor.

scientific article published on October 2010

Role of inhibitory proteins as modulators of oscillations in NFB signalling

scientific article published in March 2009

Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol

scientific article

Structural insights into a unique inhibitor binding pocket in kinesin spindle protein

scientific article

The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK.

scientific article published on 24 January 2008

Triphenylbutanamines: Kinesin Spindle Protein Inhibitors with in Vivo Antitumor Activity

scientific article

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