List of works - Maria Dolores Sanchez-niño

'That Obscure Object of Desire': in systemic lupus erythematosus B-cell activating factor/B-lymphocyte stimulator is targeted both by the immune system and by physicians

scientific article

2012 update on diabetic kidney disease: the expanding spectrum, novel pathogenic insights and recent clinical trials.

scientific article published on August 2012

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications

scientific article

3,4-DGE is cytotoxic and decreases HSP27/HSPB1 in podocytes.

scientific article published on 15 December 2013

A CLCNKA polymorphism (rs10927887; p.Arg83Gly) previously linked to heart failure is associated with the estimated glomerular filtration rate in the RENASTUR cohort

scientific article published on 9 July 2013

A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI.

scientific article

A slit in podocyte death

scientific article published on January 2008

AG490 promotes HIF-1α accumulation by inhibiting its hydroxylation.

scientific article

Acute kidney injury transcriptomics unveils a relationship between inflammation and ageing

scientific article

Advances in understanding the role of angiotensin-regulated proteins in kidney diseases

Albumin downregulates Klotho in tubular cells

scientific article published on 7 February 2018

Albumin-induced apoptosis of tubular cells is modulated by BASP1.

scientific article

Association of kidney fibrosis with urinary peptides: a path towards non-invasive liquid biopsies?

scientific article published on 5 December 2017

Atherosclerosis in Chronic Kidney Disease: More, Less, or Just Different?

scientific article published on 15 August 2019

BASP1 promotes apoptosis in diabetic nephropathy.

scientific article

Bcl3: a regulator of NF-κB inducible by TWEAK in acute kidney injury with anti-inflammatory and antiapoptotic properties in tubular cells

scientific article published on 7 July 2017

Beyond proteinuria: VDR activation reduces renal inflammation in experimental diabetic nephropathy

scientific article published on 14 December 2011

CD74 in Kidney Disease

scientific article

CXCL16 in kidney and cardiovascular injury

scientific article published on 02 May 2014

Cardiovascular risk biomarkers in CKD: the inflammation link and the road less traveled

scientific article published on 11 September 2012

Caspase-12 and Diabetic Nephropathy: From Mice to Men?

scientific article published on 06 May 2010

Cell death-based approaches in treatment of the urinary tract-associated diseases: a fight for survival in the killing fields.

scientific article

Chronicity following ischaemia-reperfusion injury depends on tubular-macrophage crosstalk involving two tubular cell-derived CSF-1R activators: CSF-1 and IL-34.

scientific article published on 24 March 2016

Chronodisruption: A Poorly Recognized Feature of CKD

scientific article published on 28 February 2020

Circulating CXCL16 in Diabetic Kidney Disease.

scientific article published on 26 September 2016

Clinical proteomics in kidney disease as an exponential technology: heading towards the disruptive phase

scientific article published on 31 March 2017

Correction: Identification of a Potent Endothelium-Derived Angiogenic Factor.

scientific article published on 13 August 2013

Deferasirox nephrotoxicity-the knowns and unknowns

scientific article

Deferasirox-induced iron depletion promotes BclxL downregulation and death of proximal tubular cells

scientific article published on 31 January 2017

Design and optimization strategies for the development of new drugs that treat chronic kidney disease

scientific article published on 18 November 2019

Designing drugs that combat kidney damage.

scientific article published on 03 April 2015

Diagnosis and treatment of Fabry disease

scientific article published on 29 November 2016

Dietary Care for ADPKD Patients: Current Status and Future Directions

scientific article published on 12 July 2019

Differential effects of oral and intravenous l-carnitine on serum lipids: is the microbiota the answer?

scientific article

Does wealth make health? Cherchez la renal replacement therapy

scientific article

Downregulation of kidney protective factors by inflammation: role of transcription factors and epigenetic mechanisms

scientific article

Effects of Pentoxifylline on Soluble Klotho Concentrations and Renal Tubular Cell Expression in Diabetic Kidney Disease

scientific article published on 04 June 2018

Enzyme replacement therapy dose and Fabry nephropathy

scientific article published on 01 August 2018

Evaluation of the efficacy and safety of three dosing regimens of agalsidase alfa enzyme replacement therapy was underpowered

scientific article published on 2 November 2015

Expression of uPAR in Urinary Podocytes of Patients with Fabry Disease.

scientific article

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid-Induced AKI.

scientific article published on 27 June 2016

Fibrosis: a key feature of Fabry disease with potential therapeutic implications

scientific article published on 06 August 2013

Fn14 in podocytes and proteinuric kidney disease.

scientific article

Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy.

scientific article published on 26 May 2010

HCV infection and miravirsen

scientific article

HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated by high glucose and angiotensin II

scientific journal article

Histone lysine crotonylation during acute kidney injury in mice

scientific article published on 28 April 2016

Horizon 2020 in Diabetic Kidney Disease: The Clinical Trial Pipeline for Add-On Therapies on Top of Renin Angiotensin System Blockade

scientific article (publication date: 2015)

Identification of a potent endothelium-derived angiogenic factor

scientific article (publication date: 2013)

Impact of Altered Intestinal Microbiota on Chronic Kidney Disease Progression

scientific article published on 19 July 2018

Increased urinary CD80 excretion and podocyturia in Fabry disease

scientific article published on 13 October 2016

Increased urinary osmolyte excretion indicates chronic kidney disease severity and progression rate

scientific article published on 14 March 2018

Inflammatory Cytokines as Uremic Toxins: "Ni Son Todos Los Que Estan, Ni Estan Todos Los Que Son".

scientific article

Inflammatory cytokines and survival factors from serum modulate tweak-induced apoptosis in PC-3 prostate cancer cells

scientific article

Is it or is it not a pathogenic mutation? Is it or is it not the podocyte?

scientific article published on October 2012

Kidney Injury Marker 1 and Neutrophil Gelatinase-Associated Lipocalin in Chronic Kidney Disease.

scientific article

Klotho to treat kidney fibrosis

scientific article

Klotho, phosphate and inflammation/ageing in chronic kidney disease ⬇️

scientific article published on December 1, 2012

Klotho, the elusive kidney-derived anti-ageing factor

scientific article published on 28 September 2019

Lesinurad: what the nephrologist should know

scientific article published on 26 May 2017

Loss of NLRP6 expression increases the severity of acute kidney injury

scientific article published on 01 April 2020

Low dose aspirin increases 15-epi-lipoxin A4 levels in diabetic chronic kidney disease patients

scientific article published on 24 August 2017

Lyso-Gb3 Increases αvβ3 Integrin Gene Expression in Cultured Human Podocytes in Fabry Nephropathy

scientific article published on 13 November 2020

Lyso-Gb3 activates Notch1 in human podocytes

scientific article published on 23 July 2015

Lyso-Gb3 modulates the gut microbiota and decreases butyrate production

scientific article published on 19 August 2019

MAGE genes in the kidney: identification of MAGED2 as upregulated during kidney injury and in stressed tubular cells

article

MAP3K kinases and kidney injury

scientific article published on 10 June 2019

MIF, CD74 and other partners in kidney disease: tales of a promiscuous couple.

scientific article published on 07 September 2012

MXRA5 is a TGF-β1-regulated human protein with anti-inflammatory and anti-fibrotic properties

scientific article

Macrophages and recently identified forms of cell death

scientific article published on 26 June 2013

Mitochondria-targeted therapies for acute kidney injury

scientific article published on 08 August 2014

Mitogen-Activated Protein Kinase 14 Promotes AKI.

scientific article published on 12 September 2016

Modifiable risk factors for increased arterial stiffness in outpatient nephrology

scientific article

Molecular pathways driving omeprazole nephrotoxicity

scientific article published on 12 February 2020

Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes

scientific article published on 9 October 2009

NF-kappaB in renal inflammation

scientific article published on 22 July 2010

NFκBiz protein downregulation in acute kidney injury: Modulation of inflammation and survival in tubular cells.

scientific article published on 8 January 2016

NIK as a Druggable Mediator of Tissue Injury

scientific article published on 26 March 2019

Next-generation phosphate binders: focus on iron-based binders

scientific article published on June 2014

Non-canonical NFκB activation promotes chemokine expression in podocytes

scientific article published on 29 June 2016

Notch3 and kidney injury: never two without three

Nutrients Turned into Toxins: Microbiota Modulation of Nutrient Properties in Chronic Kidney Disease

scientific article

Obesity and chronic kidney disease progression-the role of a new adipocytokine: C1q/tumour necrosis factor-related protein-1

scientific article published on 11 October 2018

Osteoprotegerin and kidney disease

scientific article published on 23 April 2014

Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine

scientific article

Out of the TWEAKlight: Elucidating the Role of Fn14 and TWEAK in Acute Kidney Injury

scientific article published on May 2016

PCSK9 in diabetic kidney disease

scientific article published on 20 July 2016

PGC-1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI

scientific article published on 12 June 2019

Paricalcitol for reduction of albuminuria in diabetes.

scientific article

Podocytes are new cellular targets of haemoglobin-mediated renal damage.

scientific article published on 4 December 2017

Podocyturia: why it may have added value in rare diseases

scientific article published on 05 October 2018

Progress in the development of animal models of acute kidney injury and its impact on drug discovery

scientific article published on 29 April 2013

Research update for articles published in EJCI in 2016

article

Respuesta

scientific article published on 23 June 2017

Sarcopenia in CKD: a roadmap from basic pathogenetic mechanisms to clinical trials

scientific article published on 05 February 2019

TNF superfamily: a growing saga of kidney injury modulators.

scientific article

TWEAK (tumor necrosis factor-like weak inducer of apoptosis) activates CXCL16 expression during renal tubulointerstitial inflammation

scientific article published on 25 January 2012

TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21

scientific article (publication date: 29 January 2010)

TWEAK and RIPK1 mediate a second wave of cell death during AKI.

scientific article published on 27 March 2018

TWEAK and the kidney: the dual role of a multifunctional cytokine.

scientific article published on January 2011

TWEAK and the progression of renal disease: clinical translation

scientific article

TWEAK favors phosphate-induced calcification of vascular smooth muscle cells through canonical and non-canonical activation of NFκB.

scientific article published on 21 July 2016

TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells.

scientific article published on 20 June 2018

TWEAK promotes peritoneal inflammation

scientific article

TWEAK, a multifunctional cytokine in kidney injury

scientific article published on 22 June 2011

TWEAK/Fn14 and Non-Canonical NF-kappaB Signaling in Kidney Disease

scientific article published on 10 December 2013

Targeting epigenetic DNA and histone modifications to treat kidney disease

scientific article published on 9 March 2018

Targeting inflammation in diabetic kidney disease: early clinical trials

scientific article

Targeting of regulated necrosis in kidney disease

scientific article

Tenofovir nephrotoxicity: 2011 update

scientific article published on 7 June 2011

The Human Plasma Lipidome

scientific article published on 01 February 2012

The Role of PGC-1α and Mitochondrial Biogenesis in Kidney Diseases

scientific article published on 24 February 2020

The Spanish Society of Nephrology (SENEFRO) commentary to the Spain GBD 2016 report: Keeping chronic kidney disease out of sight of health authorities will only magnify the problem

article

The cytokine TWEAK modulates renal tubulointerstitial inflammation

scientific article published on 30 January 2008

The demise of calcium-based phosphate binders

scientific article published on 19 July 2013

The inflammatory cytokine TWEAK decreases PGC-1α expression and mitochondrial function in acute kidney injury

article published in 2016

The inflammatory cytokines TWEAK and TNFα reduce renal klotho expression through NFκB.

scientific article published on 30 June 2011

The meaning of urinary creatinine concentration

scientific article published on 01 April 2011

The new marker YKL-40, a molecule related to inflammation, is associated with cardiovascular events in stable haemodialysis patients

scientific article published on 20 May 2019

Thrombotic microangiopathy: expanding genetic, clinical and therapeutic spectra and the need for worldwide implementation of recent advances

scientific article

Transcriptomics illustrate a deadly TRAIL to diabetic nephropathy

scientific article published in January 2009

Translational science in chronic kidney disease

scientific article published on 30 June 2017

Translational value of animal models of kidney failure

scientific article published on 24 March 2015

Tweak induces proliferation in renal tubular epithelium: a role in uninephrectomy induced renal hyperplasia

scientific article published in May 2009

Undetectable serum calcidiol: not everything that glitters is gold

scientific article published on 28 January 2012

Unilateral ureteral obstruction: beyond obstruction.

scientific article published on 27 September 2013

Unraveling the drivers and consequences of gut microbiota disruption in Fabry disease: the lyso-Gb3 link

scientific article published on 01 March 2020

Unravelling drug-induced hypertension: molecular mechanisms of aldosterone-independent mineralocorticoid receptor activation by posaconazole

Urine metabolomics insight into acute kidney injury point to oxidative stress disruptions in energy generation and H2S availability

scientific article published on 4 October 2017

Uromodulin, Inflammasomes, and Pyroptosis

scientific article published on 18 October 2012

Working towards novel albuminuria endpoints in chronic kidney disease

scientific article published on 08 January 2019

[TWEAK, the facilitator of acute kidney injury]

scientific article published on 01 January 2008

p-cresyl sulphate has pro-inflammatory and cytotoxic actions on human proximal tubular epithelial cells.

scientific article

List of works by Maria Dolores Sanchez-niño

'That Obscure Object of Desire': in systemic lupus erythematosus B-cell activating factor/B-lymphocyte stimulator is targeted both by the immune system and by physicians

2012 update on diabetic kidney disease: the expanding spectrum, novel pathogenic insights and recent clinical trials.

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications

3,4-DGE is cytotoxic and decreases HSP27/HSPB1 in podocytes.

A CLCNKA polymorphism (rs10927887; p.Arg83Gly) previously linked to heart failure is associated with the estimated glomerular filtration rate in the RENASTUR cohort

A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI.

A slit in podocyte death

AG490 promotes HIF-1α accumulation by inhibiting its hydroxylation.

Acute kidney injury transcriptomics unveils a relationship between inflammation and ageing

Advances in understanding the role of angiotensin-regulated proteins in kidney diseases

Albumin downregulates Klotho in tubular cells

Albumin-induced apoptosis of tubular cells is modulated by BASP1.

Association of kidney fibrosis with urinary peptides: a path towards non-invasive liquid biopsies?

Atherosclerosis in Chronic Kidney Disease: More, Less, or Just Different?

BASP1 promotes apoptosis in diabetic nephropathy.

Bcl3: a regulator of NF-κB inducible by TWEAK in acute kidney injury with anti-inflammatory and antiapoptotic properties in tubular cells

Beyond proteinuria: VDR activation reduces renal inflammation in experimental diabetic nephropathy

CD74 in Kidney Disease

CXCL16 in kidney and cardiovascular injury

Cardiovascular risk biomarkers in CKD: the inflammation link and the road less traveled

Caspase-12 and Diabetic Nephropathy: From Mice to Men?

Cell death-based approaches in treatment of the urinary tract-associated diseases: a fight for survival in the killing fields.

Chronicity following ischaemia-reperfusion injury depends on tubular-macrophage crosstalk involving two tubular cell-derived CSF-1R activators: CSF-1 and IL-34.

Chronodisruption: A Poorly Recognized Feature of CKD

Circulating CXCL16 in Diabetic Kidney Disease.

Clinical proteomics in kidney disease as an exponential technology: heading towards the disruptive phase

Correction: Identification of a Potent Endothelium-Derived Angiogenic Factor.

Deferasirox nephrotoxicity-the knowns and unknowns

Deferasirox-induced iron depletion promotes BclxL downregulation and death of proximal tubular cells

Design and optimization strategies for the development of new drugs that treat chronic kidney disease

Designing drugs that combat kidney damage.

Diagnosis and treatment of Fabry disease

Dietary Care for ADPKD Patients: Current Status and Future Directions

Differential effects of oral and intravenous l-carnitine on serum lipids: is the microbiota the answer?

Does wealth make health? Cherchez la renal replacement therapy

Downregulation of kidney protective factors by inflammation: role of transcription factors and epigenetic mechanisms

Effects of Pentoxifylline on Soluble Klotho Concentrations and Renal Tubular Cell Expression in Diabetic Kidney Disease

Enzyme replacement therapy dose and Fabry nephropathy

Evaluation of the efficacy and safety of three dosing regimens of agalsidase alfa enzyme replacement therapy was underpowered

Expression of uPAR in Urinary Podocytes of Patients with Fabry Disease.

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid-Induced AKI.

Fibrosis: a key feature of Fabry disease with potential therapeutic implications

Fn14 in podocytes and proteinuric kidney disease.

Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy.

HCV infection and miravirsen

HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated by high glucose and angiotensin II

Histone lysine crotonylation during acute kidney injury in mice

Horizon 2020 in Diabetic Kidney Disease: The Clinical Trial Pipeline for Add-On Therapies on Top of Renin Angiotensin System Blockade

Identification of a potent endothelium-derived angiogenic factor

Impact of Altered Intestinal Microbiota on Chronic Kidney Disease Progression

Increased urinary CD80 excretion and podocyturia in Fabry disease

Increased urinary osmolyte excretion indicates chronic kidney disease severity and progression rate

Inflammatory Cytokines as Uremic Toxins: "Ni Son Todos Los Que Estan, Ni Estan Todos Los Que Son".

Inflammatory cytokines and survival factors from serum modulate tweak-induced apoptosis in PC-3 prostate cancer cells

Is it or is it not a pathogenic mutation? Is it or is it not the podocyte?

Kidney Injury Marker 1 and Neutrophil Gelatinase-Associated Lipocalin in Chronic Kidney Disease.

Klotho to treat kidney fibrosis

Klotho, phosphate and inflammation/ageing in chronic kidney disease ⬇️

Klotho, the elusive kidney-derived anti-ageing factor

Lesinurad: what the nephrologist should know

Loss of NLRP6 expression increases the severity of acute kidney injury

Low dose aspirin increases 15-epi-lipoxin A4 levels in diabetic chronic kidney disease patients

Lyso-Gb3 Increases αvβ3 Integrin Gene Expression in Cultured Human Podocytes in Fabry Nephropathy

Lyso-Gb3 activates Notch1 in human podocytes

Lyso-Gb3 modulates the gut microbiota and decreases butyrate production

MAGE genes in the kidney: identification of MAGED2 as upregulated during kidney injury and in stressed tubular cells

MAP3K kinases and kidney injury

MIF, CD74 and other partners in kidney disease: tales of a promiscuous couple.

MXRA5 is a TGF-β1-regulated human protein with anti-inflammatory and anti-fibrotic properties

Macrophages and recently identified forms of cell death

Mitochondria-targeted therapies for acute kidney injury

Mitogen-Activated Protein Kinase 14 Promotes AKI.

Modifiable risk factors for increased arterial stiffness in outpatient nephrology

Molecular pathways driving omeprazole nephrotoxicity

Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes

NF-kappaB in renal inflammation

NFκBiz protein downregulation in acute kidney injury: Modulation of inflammation and survival in tubular cells.

NIK as a Druggable Mediator of Tissue Injury

Next-generation phosphate binders: focus on iron-based binders