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List of works by Francisco Pérez-Vizcaíno

Activation of BKCa channels by nitric oxide prevents coronary artery endothelial dysfunction in ouabain-induced hypertensive rats.

scientific article published in January 2009

Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction

scientific journal article

Activation of peroxisome proliferator-activated receptor-β/-δ (PPARβ/δ) prevents endothelial dysfunction in type 1 diabetic rats

scientific article published in August 2012

Acute and chronic captopril, but not prazosin or nifedipine, normalize alterations in adrenergic intracellular Ca2+ handling observed in the mesenteric arterial tree of spontaneously hypertensive rats

scientific article published on 22 December 2004

Age-related differences in vasoconstrictor responses to isoprostanes in piglet pulmonary and mesenteric vascular smooth muscle

scientific article published on 21 April 2005

Aminophylline preferentially inhibits chloroethylclonidine-insensitive alpha-adrenoceptor-mediated contractions in rat aorta.

scientific article

Antihypertensive Effects of Probiotics.

scientific article published on April 2017

Antihypertensive effects of peroxisome proliferator-activated receptor-β activation in spontaneously hypertensive rats

scientific journal article

Antihypertensive effects of peroxisome proliferator-activated receptor-β/δ activation.

scientific article published on 23 November 2016

Antioxidant effect of human adult adipose-derived stromal stem cells in alveolar epithelial cells undergoing stretch

scientific article published on 30 April 2013

Cardiovascular effects of isorhamnetin and quercetin in isolated rat and porcine vascular smooth muscle and isolated rat atria

scientific article published in April 2002

Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.

scientific article

Carotid body function and ventilatory responses in intermittent hypoxia. Evidence for anomalous brainstem integration of arterial chemoreceptor input.

scientific article

Celecoxib blocks cardiac Kv1.5, Kv4.3 and Kv7.1 (KCNQ1) channels: effects on cardiac action potentials

scientific article published on 18 September 2010

Ceramide inhibits Kv currents and contributes to TP-receptor-induced vasoconstriction in rat and human pulmonary arteries

scientific article published on 13 April 2011

Chronic (-)-epicatechin improves vascular oxidative and inflammatory status but not hypertension in chronic nitric oxide-deficient rats.

scientific article published on 13 September 2011

Chronic administration of genistein improves endothelial dysfunction in spontaneously hypertensive rats: involvement of eNOS, caveolin and calmodulin expression and NADPH oxidase activity

scientific article published on 01 February 2007

Chronic hydroxychloroquine improves endothelial dysfunction and protects kidney in a mouse model of systemic lupus erythematosus

scientific article published on 19 May 2014

Chronic peroxisome proliferator-activated receptorβ/δ agonist GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity

scientific article published in September 2015

Cirrhosis decreases vasoconstrictor response to electrical field stimulation in rat mesenteric artery: role of calcitonin gene-related peptide

scientific article published on 10 December 2010

Cytosolic Ca2+ and phosphoinositide hydrolysis linked to constitutively active alpha 1D-adrenoceptors in vascular smooth muscle

scientific article published on 6 March 2003

Decreased expression of aortic KIR6.1 and SUR2B in hypertension does not correlate with changes in the functional role of K(ATP) channels.

scientific article published on 30 March 2008

Diabetes induces pulmonary artery endothelial dysfunction by NADPH oxidase induction.

scientific article published on 22 August 2008

Different cardiovascular protective effects of quercetin administered orally or intraperitoneally in spontaneously hypertensive rats

scientific article published on 01 June 2012

Different patterns of pulmonary vascular disease induced by type 1 diabetes and moderate hypoxia in rats.

scientific article published on 13 January 2012

Effect of tyrosine kinase and tyrosine phosphatase inhibitors on aortic contraction and induction of nitric oxide synthase.

scientific article

Effects of (S)-nafenodone on 45Ca2+ fluxes and contractions in rat isolated vascular smooth muscle

scientific article published in February 1993

Effects of (S)-nafenodone, a new antidepressant, in isolated guinea-pig atrial and ventricular muscle fibres

scientific article published in June 1991

Effects of Antihypertensive Drugs on Blood Pressure and Metabolic Alterations in the Fructose-Induced Hypertensive Rat

scientific article published on 01 July 1996

Effects of Visnagin on Cyclic Nucleotide Phosphodiesterases and Their Role in its Inhibitory Effects on Vascular Smooth Muscle Contraction

scientific article published in January 1999

Effects of aminophylline on contractions and 45Ca uptake in isolated rat vascular smooth muscle

scientific article

Effects of chronic quercetin treatment on hepatic oxidative status of spontaneously hypertensive rats

scientific article

Effects of peroxisome proliferator-activated receptor-β activation in endothelin-dependent hypertension

scientific article published on 10 June 2013

Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle

scientific article published in October 1997

Effects of the flavonoid quercetin and its methylated metabolite isorhamnetin in isolated arteries from spontaneously hypertensive rats.

scientific article

Elevated pulmonary arterial pressure in Zucker diabetic fatty rats

scientific article published in PLoS ONE

Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries

scientific article

Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension

scientific article published in January 2012

Epicatechin: endothelial function and blood pressure.

scientific article published on 29 March 2012

Flavonols and cardiovascular disease ⬇️

scientific article published on September 15, 2010

Genistein restores caveolin-1 and AT-1 receptor expression and vascular function in large vessels of ovariectomized hypertensive rats

scientific article published in September 2007

Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.

scientific article published on 14 August 2008

Glucuronidated metabolites of the flavonoid quercetin do not auto-oxidise, do not generate free radicals and do not decrease nitric oxide bioavailability.

scientific article published on 16 May 2008

Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.

scientific article

Hypoxia sensing in the fetal chicken femoral artery is mediated by the mitochondrial electron transport chain

scientific article published on 20 January 2010

Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats

scientific article published in August 2006

Inhibitory effects of quercetin and staurosporine on phasic contractions in rat vascular smooth muscle

scientific article published in September 1994

Involvement of protein kinase C in reduced relaxant responses to the NO/cyclic GMP pathway in piglet pulmonary arteries contracted by the thromboxane A2-mimetic U46619.

scientific article published in August 1997

Kv7 channels critically determine coronary artery reactivity: left-right differences and down-regulation by hyperglycaemia

scientific article published on 23 January 2015

Lack of beneficial metabolic effects of quercetin in adult spontaneously hypertensive rats.

scientific article

Lack of synergistic interaction between quercetin and catechin in systemic and pulmonary vascular smooth muscle

scientific article published on 10 December 2010

Lactobacillus Fermentum Improves Tacrolimus-Induced Hypertension by Restoring Vascular Redox State and Improving eNOS Coupling.

scientific article

Levosimendan increases portal blood flow and attenuates intestinal intramucosal acidosis in experimental septic shock.

scientific article published in September 2010

Maturation of O2 sensing and signaling in the chicken ductus arteriosus.

scientific article published on 17 July 2009

Modulation of nitric oxide by flavonoids.

scientific article

Neutral sphingomyelinase, NADPH oxidase and reactive oxygen species. Role in acute hypoxic pulmonary vasoconstriction.

scientific article published in October 2011

Nitric oxide (NO) scavenging and NO protecting effects of quercetin and their biological significance in vascular smooth muscle.

scientific article published in April 2004

Ontogeny of chicken ductus arteriosus response to oxygen and vasoconstrictors

scientific article published on 17 August 2006

PPARβ activation restores the high glucose-induced impairment of insulin signalling in endothelial cells

scientific article published on June 2014

Postnatal maturation of phosphodiesterase 5 (PDE5) in piglet pulmonary arteries: activity, expression, effects of PDE5 inhibitors, and role of the nitric oxide/cyclic GMP pathway.

scientific article

Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction.

scientific article

Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats.

scientific article published in September 2002

Protective vascular effects of quercitrin in acute TNBS-colitis in rats: the role of nitric oxide

scientific article published on 13 July 2017

Proteomic Study of Plasma from Moderate Hypercholesterolemic Patients

scientific article published in September 2006

Pulmonary arterial dysfunction in insulin resistant obese Zucker rats ⬇️

scientific article

Pulmonary vascular dysfunction induced by high tidal volume mechanical ventilation.

scientific article

Pulmonary versus systemic effects of vasodilator drugs: an in vitro study in isolated intrapulmonary and mesenteric arteries of neonatal piglets

scientific article published in October 1996

Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats

scientific article published in 2015

Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC.

scientific article published on 16 March 2008

Relaxant effects of the soluble guanylate cyclase activator and NO sensitizer YC-1 in piglet pulmonary arteries.

scientific article published on 9 March 2006

Research trends in flavonoids and health

scientific article published on 23 March 2018

Response of chicken ductus arteriosus to hypercarbic and normocarbic acidosis

scientific article published on 10 December 2009

Riociguat versus sildenafil on hypoxic pulmonary vasoconstriction and ventilation/perfusion matching.

scientific article published on 24 January 2018

Role of K+ channel opening and stimulation of cyclic GMP in the vasorelaxant effects of nicorandil in isolated piglet pulmonary and mesenteric arteries: relative efficacy and interactions between both pathways

scientific article published in March 1998

Role of Protein Kinase C and Its Adaptor Protein p62 in Voltage-Gated Potassium Channel Modulation in Pulmonary Arteries

scientific article published on 3 August 2007

Role of Reactive Oxygen Species in Kv Channel Inhibition and Vasoconstriction Induced by TP Receptor Activation in Rat Pulmonary Arteries

scientific article published in December 2006

Role of UCP2 in the protective effects of PPARβ/δ activation on lipopolysaccharide-induced endothelial dysfunction.

scientific article published on 11 May 2016

Role of tetrahydrobiopterin in pulmonary vascular remodelling associated with pulmonary fibrosis.

scientific article published on 5 June 2013

SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging

scientific journal article

Soluble guanylyl cyclase during postnatal porcine pulmonary maturation.

scientific article published on 24 September 2004

Soy isoflavones improve endothelial function in spontaneously hypertensive rats in an estrogen-independent manner: role of nitric-oxide synthase, superoxide, and cyclooxygenase metabolites

scientific article published on 15 June 2005

The dietary flavonoid quercetin activates BKCa currents in coronary arteries via production of H2O2. Role in vasodilatation

scientific article published on 15 January 2007

The flavonoid paradox: conjugation and deconjugation as key steps for the biological activity of flavonoids

scientific article published on 04 May 2012

The flavonoid quercetin induces acute vasodilator effects in healthy volunteers: correlation with beta-glucuronidase activity

scientific article published on 27 July 2014

The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells

scientific article published on 9 June 2006

The flavonoid quercetin reverses pulmonary hypertension in rats

scientific article

Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction: role of protein kinase Czeta.

scientific article published on 11 September 2003

Type 1 diabetes-induced hyper-responsiveness to 5-hydroxytryptamine in rat pulmonary arteries via oxidative stress and induction of cyclooxygenase-2.

scientific article

Upregulation of SK3 and IK1 channels contributes to the enhanced endothelial calcium signaling and the preserved coronary relaxation in obese Zucker rats

scientific article

Vascular and Central Activation of Peroxisome Proliferator-Activated Receptor-β Attenuates Angiotensin II-Induced Hypertension: Role of RGS-5.

scientific article

Vascular deconjugation of quercetin glucuronide: The flavonoid paradox revealed?

scientific article published on 7 October 2011

Vascular superoxide production by endothelin-1 requires Src non-receptor protein tyrosine kinase and MAPK activation.

scientific article published on 6 May 2010

Vasoconstrictor and Vasodilator Effects of Disopyramide on Isolated Rat Vascular Smooth Muscle

scientific article published in November 1998

Vasodilator effects of quercetin in isolated rat vascular smooth muscle

scientific article published in August 1993

Vasodilator effects of visnagin in isolated rat vascular smooth muscle

scientific article published in November 1995

Vasorelaxant effects of the bioflavonoid chrysin in isolated rat aorta

scientific article published in August 2001

Vitamin D Receptor Deficiency Upregulates Pulmonary Artery Kv7 Channel Activity

scientific article published in 2023

Wine polyphenols improve endothelial function in large vessels of female spontaneously hypertensive rats

scientific article published on 7 February 2008

Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.

scientific article

miR-1 is increased in pulmonary hypertension and downregulates Kv1.5 channels in rat pulmonary arteries

scientific article published on 21 June 2018

mu- and delta-opioid receptor-mediated contractile effects on rat aortic vascular smooth muscle

scientific article

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