List of works - Annette Gilchrist

A dominant-negative strategy for studying roles of G proteins in vivo.

scientific article

A perspective on more effective GPCR-targeted drug discovery efforts.

scientific article published on April 2008

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

scientific article

An overview of drug screening using primary and embryonic stem cells.

scientific article published on August 2008

Antagonist minigenes identify genes regulated by parathyroid hormone through G protein-selective and G protein co-regulated mechanisms in osteoblastic cells

scientific journal article

Antagonists of the receptor-G protein interface block Gi-coupled signal transduction.

scientific article

Are we just learning the scales on the chemokine receptor pianos?

scientific article published in May 2012

BJCP 40th anniversary: moving forward, looking back.

scientific article

Endothelial cell-surface gp60 activates vesicle formation and trafficking via G(i)-coupled Src kinase signaling pathway.

scientific article

Evaluation of Dose Fractionated Polymyxin B on Acute Kidney Injury: A Translational In Vivo Rat Model

scientific article published on 18 February 2020

Experimental design and analysis and their reporting: new guidance for publication in BJP.

scientific article published on July 2015

G alpha COOH-terminal minigene vectors dissect heterotrimeric G protein signaling.

scientific article published on 5 February 2002

G alpha12/G alpha13 subunits of heterotrimeric G proteins mediate parathyroid hormone activation of phospholipase D in UMR-106 osteoblastic cells.

scientific article published on 10 February 2005

Heterotrimeric G proteins.

scientific article published on April 1996

High Expression and Activation of MAP Kinase-activated Protein Kinase 2 in Cardiac Muscle Cells

scientific article published on 01 August 1997

Identifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, β-arrestin translocation and chemotaxis assays

scientific article

Identifying medical wearables and sensor technologies that deliver data on clinical endpoints

scientific article published on 6 November 2015

Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β

scientific article

Modulating G-protein-coupled receptors: from traditional pharmacology to allosterics

scientific article published on 17 July 2007

Modulation of PAR(1) signalling by benzimidazole compounds

scientific article

Organised crime against the academic peer review system.

scientific article published on June 2016

Prevalence of a Cefazolin Inoculum Effect Associated with blaZ Gene Types among Methicillin-Susceptible Staphylococcus aureus Isolates from Four Major Medical Centers in Chicago

scientific article published on 27 July 2018

Second annual GPCRs: from orphan to blockbuster

scientific article published in October 2004

Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin.

scientific article

Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation

scientific article published on 20 May 2009

The use of immortalized cell lines in GPCR screening: the good, bad and ugly.

scientific article published on August 2008

Therapeutic potential of CCR1 antagonists for multiple myeloma.

scientific article

Thrombin Induces Proteinase-activated Receptor-1 Gene Expression in Endothelial Cells via Activation of Gi-linked Ras/Mitogen-activated Protein Kinase Pathway

article

Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Galphaq and cooperation between ERK1/2 and Rho kinase signaling pathways

scientific article published on 19 March 2008

Thrombin receptors activate G(o) proteins in endothelial cells to regulate intracellular calcium and cell shape changes.

scientific article published on 30 May 2002

Use of peptides-on-plasmids combinatorial library to identify high-affinity peptides that bind rhodopsin.

scientific article

List of works by Annette Gilchrist

A dominant-negative strategy for studying roles of G proteins in vivo.

A perspective on more effective GPCR-targeted drug discovery efforts.

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

An overview of drug screening using primary and embryonic stem cells.

Antagonist minigenes identify genes regulated by parathyroid hormone through G protein-selective and G protein co-regulated mechanisms in osteoblastic cells

Antagonists of the receptor-G protein interface block Gi-coupled signal transduction.

Are we just learning the scales on the chemokine receptor pianos?

BJCP 40th anniversary: moving forward, looking back.

Endothelial cell-surface gp60 activates vesicle formation and trafficking via G(i)-coupled Src kinase signaling pathway.

Evaluation of Dose Fractionated Polymyxin B on Acute Kidney Injury: A Translational In Vivo Rat Model

Experimental design and analysis and their reporting: new guidance for publication in BJP.

G alpha COOH-terminal minigene vectors dissect heterotrimeric G protein signaling.

G alpha12/G alpha13 subunits of heterotrimeric G proteins mediate parathyroid hormone activation of phospholipase D in UMR-106 osteoblastic cells.

Heterotrimeric G proteins.

High Expression and Activation of MAP Kinase-activated Protein Kinase 2 in Cardiac Muscle Cells

Identifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, β-arrestin translocation and chemotaxis assays

Identifying medical wearables and sensor technologies that deliver data on clinical endpoints

Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β

Modulating G-protein-coupled receptors: from traditional pharmacology to allosterics

Modulation of PAR(1) signalling by benzimidazole compounds

Organised crime against the academic peer review system.

Prevalence of a Cefazolin Inoculum Effect Associated with blaZ Gene Types among Methicillin-Susceptible Staphylococcus aureus Isolates from Four Major Medical Centers in Chicago

Second annual GPCRs: from orphan to blockbuster

Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin.

Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation

The use of immortalized cell lines in GPCR screening: the good, bad and ugly.

Therapeutic potential of CCR1 antagonists for multiple myeloma.

Thrombin Induces Proteinase-activated Receptor-1 Gene Expression in Endothelial Cells via Activation of Gi-linked Ras/Mitogen-activated Protein Kinase Pathway

Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Galphaq and cooperation between ERK1/2 and Rho kinase signaling pathways

Thrombin receptors activate G(o) proteins in endothelial cells to regulate intracellular calcium and cell shape changes.

Use of peptides-on-plasmids combinatorial library to identify high-affinity peptides that bind rhodopsin.