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List of works by Stephen J. McMahon

A computational model of cellular response to modulated radiation fields.

scientific article published on 26 January 2012

A general mechanistic model enables predictions of the biological effectiveness of different qualities of radiation

scientific article published on 7 September 2017

A kinetic-based model of radiation-induced intercellular signalling

scientific article

A mechanistic study of gold nanoparticle radiosensitisation using targeted microbeam irradiation.

scientific article published on 16 March 2017

A novel CBCT-based method for derivation of CTV-PTV margins for prostate and pelvic lymph nodes treated with stereotactic ablative radiotherapy.

scientific article published on 04 August 2017

A parameter sensitivity study for simulating DNA damage after proton irradiation using TOPAS-nBio

scientific article published on 26 February 2020

A robust curve-fitting procedure for the analysis of plasmid DNA strand break data from gel electrophoresis.

scientific article

Advances in modelling gold nanoparticle radiosensitization using new Geant4-DNA physics models

scientific article published on 11 September 2020

An in vitro study of the radiobiological effects of flattening filter free radiotherapy treatments.

scientific article published on 11 February 2013

An overview of current practice in external beam radiation oncology with consideration to potential benefits and challenges for nanotechnology.

scientific article published on 3 February 2017

Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest.

scientific article published on January 2013

Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticles

scientific article published on 20 June 2011

Biological modeling of gold nanoparticle enhanced radiotherapy for proton therapy

scientific article published on 08 May 2015

Bystander Signalling: Exploring Clinical Relevance Through New Approaches and New Models ⬇️

scientific article published on July 10, 2013

Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles.

scientific article

Cell-Specific Radiosensitization by Gold Nanoparticles at Megavoltage Radiation Energies ⬇️

scientific article published on November 20, 2010

Cellular signalling effects in high precision radiotherapy

scientific article published on 20 May 2015

Comment on 'implications on clinical scenario of gold nanoparticle radiosensitization in regard to photon energy, nanoparticle size, concentration and location'.

scientific article published in January 2012

Comparing gold nano-particle enhanced radiotherapy with protons, megavoltage photons and kilovoltage photons: a Monte Carlo simulation

scientific article

Comparing stochastic proton interactions simulated using TOPAS-nBio to experimental data from fluorescent nuclear track detectors.

scientific article

Conventional in vivo irradiation procedures are insufficient to accurately determine tumor responses to non-uniform radiation fields.

scientific article

DNA damage responses following exposure to modulated radiation fields

scientific article (publication date: 2012)

Dependence of gold nanoparticle radiosensitization on cell geometry.

scientific article published in May 2017

Dose enhancement effects to the nucleus and mitochondria from gold nanoparticles in the cytosol

scientific article published on 20 July 2016

Dose, dose-rate and field size effects on cell survival following exposure to non-uniform radiation fields.

scientific article published on May 2012

Dual effects of radiation bystander signaling in urothelial cancer: purinergic-activation of apoptosis attenuates survival of urothelial cancer and normal urothelial cells.

scientific article published on 24 October 2017

Evaluating Iodine-125 DNA Damage Benchmarks of Monte Carlo DNA Damage Models

scientific article published in 2022

Gold nanoparticle cellular uptake, toxicity and radiosensitisation in hypoxic conditions.

scientific article published on 17 January 2014

Gold nanoparticle induced vasculature damage in radiotherapy: Comparing protons, megavoltage photons, and kilovoltage photons.

scientific article published on October 2015

Imaging and radiation effects of gold nanoparticles in tumour cells

scientific article published on 20 January 2016

Impact of fractionation on out-of-field survival and DNA damage responses following exposure to intensity modulated radiation fields

scientific article published on 18 December 2015

Implications of intercellular signaling for radiation therapy: a theoretical dose-planning study

scientific article

In-vitro investigation of out-of-field cell survival following the delivery of conformal, intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) plans

scientific article

Intensity Modulated Radiation Fields Induce Protective Effects and Reduce Importance of Dose-Rate Effects

scientific article published on 01 July 2019

Investigating spatial fractionation and radiation induced bystander effects: a mathematical modelling approach

scientific article published in 2021

Investigating the influence of respiratory motion on the radiation induced bystander effect in modulated radiotherapy

scientific article published on 11 November 2013

Investigating the potential impact of four-dimensional computed tomography (4DCT) on toxicity, outcomes and dose escalation for radical lung cancer radiotherapy.

scientific article published on 9 December 2013

Investigation into the radiobiological consequences of pre-treatment verification imaging with megavoltage X-rays in radiotherapy

scientific article

Investigation of dose-rate effects and cell-cycle distribution under protracted exposure to ionizing radiation for various dose-rates.

scientific article

LET-weighted doses effectively reduce biological variability in proton radiotherapy planning

scientific article published on 09 November 2018

Mechanistic Modelling of DNA Repair and Cellular Survival Following Radiation-Induced DNA Damage.

scientific article published on 14 September 2016

Modelling responses to spatially fractionated radiation fields using preclinical image-guided radiotherapy.

scientific article published on 24 August 2016

Nanodosimetric effects of gold nanoparticles in megavoltage radiation therapy

scientific article published on 15 September 2011

Optimising element choice for nanoparticle radiosensitisers

scientific article published on 01 January 2016

Physical basis and biological mechanisms of gold nanoparticle radiosensitization.

scientific article published on 06 July 2012

Prostate cancer treated with brachytherapy; an exploratory study of dose-dependent biomarkers and quality of life.

scientific article published on 14 March 2017

Protein disulphide isomerase as a target for nanoparticle-mediated sensitisation of cancer cells to radiation

scientific article published on 15 April 2016

Radiotherapy in the presence of contrast agents: a general figure of merit and its application to gold nanoparticles

scientific article published on 24 September 2008

Relative biological effectiveness (RBE) and out-of-field cell survival responses to passive scattering and pencil beam scanning proton beam deliveries.

scientific article

Relative biological effectiveness variation along monoenergetic and modulated Bragg peaks of a 62-MeV therapeutic proton beam: a preclinical assessment.

scientific article published on 28 June 2014

Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions

scientific article published on 07 May 2020

Roadmap to Clinical Use of Gold Nanoparticles for Radiation Sensitization.

scientific article

Small field dosimetry for the small animal radiotherapy research platform (SARRP).

scientific article published on 28 December 2017

The Impact of Hypoxia on Out-of-Field Cell Survival after Exposure to Modulated Radiation Fields

scientific article published on 11 October 2017

The Radiobiology of Proton Therapy: Challenges and Opportunities Around Relative Biological Effectiveness

scientific article published on 15 February 2018

The linear quadratic model: usage, interpretation and challenges

scientific article published on 19 December 2018

The role of mitochondrial function in gold nanoparticle mediated radiosensitisation.

scientific article published on 16 September 2014

The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy.

scientific article published on 3 July 2014

Time and Cell Type Dependency of Survival Responses in Co-cultured Tumor and Fibroblast Cells after Exposure to Modulated Radiation Fields

scientific article published on 14 May 2015

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