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List of works by Keisuke Horiuchi

A Brief History of Tumor Necrosis Factor α – converting Enzyme: An Overview of Ectodomain Shedding ⬇️

scientific article published on January 1, 2013

A Disintegrin and Metalloprotease 10 (ADAM10) Is Indispensable for Maintenance of the Muscle Satellite Cell Pool

scientific article

ADAM10 is indispensable for longitudinal bone growth in mice

scientific article published on 13 February 2020

ADAM17 deletion in thymic epithelial cells alters aire expression without affecting T cell developmental progression

scientific article

ADAM17 regulates IL-1 signaling by selectively releasing IL-1 receptor type 2 from the cell surface.

scientific article published on 22 November 2014

Activation of TNFR1 ectodomain shedding by mitochondrial Ca2+ determines the severity of inflammation in mouse lung microvessels

scientific article

Activity-dependent proteolytic cleavage of neuroligin-1.

scientific article published on 17 October 2012

Anaplastic transformation of follicular thyroid carcinoma in a metastatic skeletal lesion presenting with paraneoplastic leukocytosis

scientific article published on 16 December 2011

Arthroscopic removal of intra-articular osteoid osteoma in the knee: case report and review of the literature

scientific article published on 24 March 2011

Brief report: requirement of TACE/ADAM17 for hair follicle bulge niche establishment

scientific article published on 01 August 2012

CT guided cryoablation for locally recurrent or metastatic bone and soft tissue tumor: initial experience.

scientific article

Chordoma-derived cell line U-CH1-N recapitulates the biological properties of notochordal nucleus pulposus cells.

scientific article

Clinical outcome after bone metastasis (BM) surgery in patients with differentiated thyroid carcinoma (DTC): a retrospective study of 40 cases

scientific article published on 7 August 2014

Computed tomography-guided resection of osteoid osteoma of the sacrum: a case report.

scientific article published on 18 June 2014

Conditional abrogation of Atm in osteoclasts extends osteoclast lifespan and results in reduced bone mass

scientific article published on 28 September 2016

Conditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF.

scientific article

Conditional inactivation of TNFα-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones

scientific article

Desmoplastic fibroma arising in the distal phalanx of the great toe: a case report.

scientific article

Detection of HEY1-NCOA2 fusion by fluorescence in-situ hybridization in formalin-fixed paraffin-embedded tissues as a possible diagnostic tool for mesenchymal chondrosarcoma

scientific article published on 01 December 2012

Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19.

scientific article published in March 2007

Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis

scientific article published on 31 October 2011

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice

scientific article

Ectodomain shedding of FLT3 ligand is mediated by TNF-alpha converting enzyme.

scientific article published on June 2009

Enhanced Functional Recovery from Spinal Cord Injury in Aged Mice after Stem Cell Transplantation through HGF Induction.

scientific article published on 06 February 2017

Enhanced susceptibility to lipopolysaccharide-induced arthritis and endotoxin shock in interleukin-32 alpha transgenic mice through induction of tumor necrosis factor alpha

scientific article

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

scientific article

Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation.

scientific article

Essential role for ADAM19 in cardiovascular morphogenesis

scientific journal article

Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2

scientific article published on 01 July 2005

GRIP1 enhances estrogen receptor alpha-dependent extracellular matrix gene expression in chondrogenic cells.

scientific article published on 24 March 2010

Gene expression profiling of mouse growth plate cartilage by laser microdissection and microarray analysis

scientific article

Generation of heterozygous fibrillin-1 mutant cloned pigs from genome-edited foetal fibroblasts

scientific article

Granulocyte-colony stimulating factor enhances load-induced muscle hypertrophy in mice

scientific article published on 03 November 2018

Growth suppression and apoptosis induction in synovial sarcoma cell lines by a novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ).

scientific article

Histochemical aspects of the vascular invasion at the erosion zone of the epiphyseal cartilage in MMP-9-deficient mice

scientific article published in June 2013

Histomorphometric analysis of minimodeling in the vertebrae in postmenopausal patients treated with anti-osteoporotic agents

scientific article

Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium

scientific article published on 31 January 2019

Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization Controls Endochondral Ossification through Hyaluronan Metabolism.

scientific article published on 8 March 2017

IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis

scientific article

Identification and analysis of function of a novel splicing variant of mouse receptor activator of NF-κB.

scientific article published on 14 December 2010

Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta

scientific journal article

Idiopathic Spinal Epidural Fat Accumulation is Associated With Hyperlipidemia

scientific article published on 29 August 2017

In vivo role of leukocyte ADAM17 in the inflammatory and host responses during E. coli-mediated peritonitis

scientific article

Inhibition of ADAM10 in satellite cells accelerates muscle regeneration following muscle injury.

scientific article published on 21 February 2018

Inhibition of PDGFR signaling prevents muscular fatty infiltration after rotator cuff tear in mice

scientific article published on 31 January 2017

Inhibition of STAT1 accelerates bone fracture healing

scientific article published in July 2010

Leukocyte ADAM17 regulates acute pulmonary inflammation.

scientific article

Lung endothelial ADAM17 regulates the acute inflammatory response to lipopolysaccharide

scientific article published on 24 February 2012

Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice.

scientific article

Metastatic patterns of myxoid/round cell liposarcoma: a review of a 25-year experience

scientific article

Multiple smooth muscle tumors arising in deep soft tissue of lower limbs with uterine leiomyomas

scientific article published on 01 July 1998

Osteonecrosis of the femoral head in Japanese adults after liver transplantation: a preliminary report

scientific article published in January 2004

Osteosarcoma with metastasis to the stomach

scientific article published on 01 March 2010

Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes.

scientific article published on 28 January 2010

Potential Involvement of Obesity-Associated Chronic Inflammation in the Pathogenesis of Idiopathic Spinal Epidural Lipomatosis

scientific article

Potential Involvement of the IL-6/JAK/STAT3 Pathway in the Pathogenesis of Intervertebral Disc Degeneration.

scientific article published on 22 November 2016

Potential role for ADAM15 in pathological neovascularization in mice

scientific article

Receptor activator of NF-kappaB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages.

scientific article

Results of sub-analysis of a phase 2 study on trabectedin treatment for extraskeletal myxoid chondrosarcoma and mesenchymal chondrosarcoma

scientific article

Rice Bodies in a Patient with Oligoarticular Juvenile Idiopathic Arthritis

scientific article published on 01 September 2019

Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin.

scientific article

Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx

scientific article published on November 2006

Synergistic antiproliferative effect of imatinib and adriamycin in platelet-derived growth factor receptor-expressing osteosarcoma cells

scientific article published on 26 May 2015

Systemic overexpression of TNFα-converting enzyme does not lead to enhanced shedding activity in vivo

scientific article

TACE (ADAM17) inhibits Schwann cell myelination

scientific article

TNF-α-converting enzyme/a disintegrin and metalloprotease-17 mediates mechanotransduction in murine tracheal epithelial cells

scientific article

Targeted ablation of p38α MAPK suppresses denervation-induced muscle atrophy.

scientific article published on 13 June 2018

The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix

scientific article published on 18 March 2011

The IRE1α-XBP1 pathway positively regulates parathyroid hormone (PTH)/PTH-related peptide receptor expression and is involved in pth-induced osteoclastogenesis.

scientific article published on 12 December 2012

The effect of timing in the administration of hepatocyte growth factor to modulate BMP-2-induced osteoblast differentiation.

scientific article

The transient appearance of zipper-like actin superstructures during the fusion of osteoclasts.

scientific article

The unfolded protein response in skeletal development and homeostasis

scientific article published on 22 March 2016

The unfolded protein response mediated by PERK is casually related to the pathogenesis of intervertebral disc degeneration

scientific article published on 28 October 2017

The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17.

scientific article

Treatment of collagen-induced arthritis with recombinant plasminogen-related protein B: a novel inhibitor of angiogenesis

scientific article published on 17 May 2011

Tumor necrosis factor-α converting enzyme inactivation ameliorates high-fat diet-induced insulin resistance and altered energy homeostasis

scientific article published on 23 July 2011

Tumor necrosis factor-α converting enzyme is a key mediator of abdominal aortic aneurysm development

scientific article published on 13 June 2011

VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling.

scientific article published on 25 September 2008

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