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List of works by Francesco Giorgino

A master course on "Methodologies for bio-medical research in diabetes".

scientific article published in October 2013

A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex

scientific article published in January 2005

Abnormalities of IGF-I signaling in the pathogenesis of diseases of the bone, brain, and fetoplacental unit in humans

scientific article published on 19 August 2008

Abnormalities of insulin-like growth factor-I signaling and impaired cell proliferation in osteoblasts from subjects with osteoporosis

scientific article

Achievement of glycaemic control is associated with improvements in lipid profile with iGlarLixi versus iGlar: A post hoc analysis of the LixiLan-L trial

scientific article published on 03 September 2019

Adherence to antihyperglycemic medications and glucagon-like peptide 1-receptor agonists in type 2 diabetes: clinical consequences and strategies for improvement.

scientific article published on 7 May 2018

Adipose tissue function and dysfunction: organ cross talk and metabolic risk

scientific article published on 25 August 2009

Adipose tissue, metabolic syndrome and polycystic ovary syndrome: from pathophysiology to treatment

scientific article published on October 2009

Associated hormonal declines in aging: DHEAS.

scientific article published in January 2005

Association between follicular fluid leptin and serum insulin levels in nonoverweight women with polycystic ovary syndrome.

scientific article

Association of TCF7L2 gene variants with low GAD autoantibody titre in LADA subjects (NIRAD Study 5).

scientific article published in June 2010

Biological specificity of visceral adipose tissue and therapeutic intervention

scientific article published on 01 October 2008

Cardiovascular disease and glycemic control in type 2 diabetes: now that the dust is settling from large clinical trials ⬇️

scientific article published on 06 February 2013

Cardiovascular protection with SGLT2 inhibitors in type 2 diabetes mellitus: does it apply to all patients?

scientific article published on 14 April 2020

Changes in tyrosine phosphorylation of insulin receptors and a 170,000 molecular weight nonreceptor protein in vivo in skeletal muscle of streptozotocin-induced diabetic rats: effects of insulin and glucose

scientific article published on March 1, 1992

Clinical aggressiveness of incidental and non-incidental thyroid cancer.

scientific article published on 2 September 2010

Clusterin transcript variants expression in thyroid tumor: a potential marker of malignancy?

scientific article published on 2 May 2015

Correction to: Pegvisomant in acromegaly: an update.

scientific article published on 28 December 2017

Cross-Talk between PPARgamma and Insulin Signaling and Modulation of Insulin Sensitivity

scientific article published on January 2009

Dehydroepiandrosterone stimulates glucose uptake in human and murine adipocytes by inducing GLUT1 and GLUT4 translocation to the plasma membrane

scientific article published on January 2004

Dexamethasone enhances insulin-like growth factor-I effects on skeletal muscle cell proliferation. Role of specific intracellular signaling pathways

scientific article published on September 1995

Diabetes and cancer: Pathophysiological fundamentals of a ‘dangerous affair’

scientific article published on 19 April 2018

Diabetes in the Time of COVID-19: A Twitter-Based Sentiment Analysis

scientific article published on 07 August 2020

Diagnostic Utility of Thyroglobulin Detection in Fine-Needle Aspiration of Cervical Cystic Metastatic Lymph Nodes from Papillary Thyroid Cancer with Negative Cytology

scientific article published on 01 December 2003

Differences in gene expression and cytokine release profiles highlight the heterogeneity of distinct subsets of adipose tissue-derived stem cells in the subcutaneous and visceral adipose tissue in humans

scientific article

Different gene expression in human heart tissue and progenitor cells from control and diabetic subjects: relevance to the pathogenesis of human diabetic cardiomyopathy.

scientific article

Dysmetabolic adipose tissue in obesity: morphological and functional characteristics of adipose stem cells and mature adipocytes in healthy and unhealthy obese subjects

scientific article published on 03 November 2020

Effect of an l-Carnitine–Containing Peritoneal Dialysate on Insulin Sensitivity in Patients Treated With CAPD: A 4-Month, Prospective, Multicenter Randomized Trial

scientific article published on 29 May 2013

Effect of once-weekly dulaglutide versus insulin glargine in people with type 2 diabetes and different baseline glycaemic patterns: A post hoc analysis of the AWARD-2 clinical trial

scientific article published on 16 August 2019

Effects of contractile activity on tyrosine phosphoproteins and PI 3-kinase activity in rat skeletal muscle

scientific article published on 01 May 1995

Efficacy and Safety of Once-Weekly Dulaglutide Versus Insulin Glargine in Patients With Type 2 Diabetes on Metformin and Glimepiride (AWARD-2).

scientific article published on 18 June 2015

Efficacy and safety of GLP-1 receptor agonists as add-on to SGLT2 inhibitors in type 2 diabetes mellitus: A meta-analysis

scientific article published on 18 December 2019

Efficacy and safety of dapagliflozin in patients with type 2 diabetes and moderate renal impairment (chronic kidney disease stage 3A): The DERIVE Study

scientific article published on 10 July 2018

Efficacy and safety of flash glucose monitoring in patients with type 1 and type 2 diabetes: a systematic review and meta-analysis

scientific article published on 01 June 2020

Efficacy and safety of insulin glargine/lixisenatide (iGlarLixi) fixed-ratio combination in older adults with type 2 diabetes

scientific article published on 30 November 2018

Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis

scientific article published on 01 March 2020

Elevated 1-hour postload plasma glucose levels identify subjects with normal glucose tolerance but impaired β-cell function, insulin resistance, and worse cardiovascular risk profile: the GENFIEV study.

scientific article published on 28 March 2013

Evidence for two insulin-like growth factor I receptors with distinct primary structure that are differentially expressed during development

article

Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells

scientific article published on 10 March 2010

Exendin-4 protects pancreatic beta cells from palmitate-induced apoptosis by interfering with GPR40 and the MKK4/7 stress kinase signalling pathway

scientific article published on 31 August 2013

Expression and secretion of the atrial natriuretic peptide in human adipose tissue and preadipocytes

scientific article

Factors associated with progression to macroalbuminuria in microalbuminuric Type 1 diabetic patients: the EURODIAB Prospective Complications Study

scientific article published on 29 May 2004

Fat depot-related differences in gene expression, adiponectin secretion, and insulin action and signalling in human adipocytes differentiated in vitro from precursor stromal cells

scientific article published on 25 October 2007

Feasibility and effectiveness of a disease and care management model in the primary health care system for patients with heart failure and diabetes (Project Leonardo).

scientific article

GLP-1 receptor agonist added to insulin versus basal-plus or basal-bolus insulin therapy in type 2 diabetes: A systematic review and meta-analysis

scholarly article by Marco Castellana et al published 18 October 2018 in Diabetes - Metabolism: Research and Reviews

GLP-1: benefits beyond pancreas.

scientific article

Glucagon-Like Peptide-1 Counteracts Oxidative Stress-Dependent Apoptosis of Human Cardiac Progenitor Cells by Inhibiting the Activation of the c-Jun N-terminal Protein Kinase Signaling Pathway

scientific article published on 17 October 2012

Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo ⬇️

scientific article published on May 1, 1993

Glycated haemoglobin does not accurately predict average capillary glucose in non insulin-treated type 2 diabetes: The PRISMA study experience

scientific article published on 21 December 2015

GnRH agonist versus GnRH antagonist in in vitro fertilization and embryo transfer (IVF/ET).

scientific article

High GADA titer increases the risk of insulin requirement in LADA patients: a 7-year follow-up (NIRAD study 7).

scientific article published on 11 September 2014

Human adipose tissue precursor cells: a new factor linking regulation of fat mass to obesity and type 2 diabetes?

scientific article published on October 2009

Human adipose tissue stem cells: relevance in the pathophysiology of obesity and metabolic diseases and therapeutic applications

scientific article published on 10 December 2012

INTERFERENCE OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS ON ERYTHROPOIESIS IN KIDNEY TRANSPLANT RECIPIENTS

scientific article published on 01 September 1997

In vivo insulin signaling in the myocardium of streptozotocin-diabetic rats: opposite effects of diabetes on insulin stimulation of glycogen synthase and c-Fos.

scientific article

Increased carotid IMT in overweight and obese women affected by Hashimoto's thyroiditis: an adiposity and autoimmune linkage?

scientific article

Influence of CAG Repeat Polymorphism on the Targets of Testosterone Action

scientific article

Insulin Glargine U100 Utilization in Patients with Type 2 Diabetes in an Italian Real-World Setting: A Retrospective Study

scientific article published on 30 December 2019

Insulin and Insulin Receptors in Adipose Tissue Development ⬇️

article

Insulin receptor expression and function in human breast cancer cell lines.

scientific article published on July 1992

Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects

scientific article

Insulin signaling in adipose tissue of patients with primary aldosteronism ⬇️

scientific article published on February 1, 2011

Insulin signaling in human visceral and subcutaneous adipose tissue in vivo

scientific article

Insulin signalling in human adipose tissue

scientific article published on April 2006

Insulin-resistant MDA-MB231 human breast cancer cells contain a tyrosine kinase inhibiting activity.

scientific article

Intensive glucose-lowering results in increased cardiovascular mortality in younger but not older individuals with type 2 diabetes

scientific article published on 15 July 2014

Intensive structured self-monitoring of blood glucose and glycemic control in noninsulin-treated type 2 diabetes: the PRISMA randomized trial

scientific article published on 04 June 2013

Interaction between the Grb10 SH2 domain and the insulin receptor carboxyl terminus

scientific article

Intrauterine growth restriction in humans is associated with abnormalities in placental insulin-like growth factor signaling

scientific article published on 24 November 2004

Involvement of the p66Shc protein in glucose transport regulation in skeletal muscle myoblasts

scientific article published on 28 October 2008

Irisin increases the expression of anorexigenic and neurotrophic genes in mouse brain

scientific article published on 19 December 2019

Islet transplantation restores normal levels of insulin receptor and substrate tyrosine phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle and myocardium of streptozocin-induced diabetic rats

scientific article published on 01 April 1999

Italian Society for the Study of Diabetes (SID)/Italian Endocrinological Society (SIE) guidelines on the treatment of hyperglycemia in Cushing's syndrome and acromegaly

scientific article published on 30 December 2015

Links between metabolic syndrome and cardiovascular autonomic dysfunction

scientific article published on 15 March 2012

Lipodystrophic diabetes mellitus: a lesson for other forms of diabetes?

scientific article

Metabolic implications of growth hormone therapy.

scientific article published on September 2008

Metabolic syndrome in subjects at high risk for type 2 diabetes: the genetic, physiopathology and evolution of type 2 diabetes (GENFIEV) study.

scientific article published on 5 November 2010

Multifactorial intervention in Type 2 diabetes: The promise of incretin-based therapies ⬇️

scientific article published on January 13, 2011

Multiple endocrine neoplasia type 2 syndromes (MEN 2): results from the ItaMEN network analysis on the prevalence of different genotypes and phenotypes

scientific article published in June 2010

Obesity

scientific article published on 01 November 2002

Oocyte morphological abnormalities in overweight women undergoing in vitro fertilization cycles

scientific article published on 18 April 2011

Overexpression of Insulin Receptors in Fibroblast and Ovary Cells Induces a Ligand-Mediated Transformed Phenotype ⬇️

scientific article published on March 1, 1991

Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases.

scientific article published on June 2017

Pathophysiology of type 2 diabetes: rationale for different oral antidiabetic treatment strategies

scientific article

Pegvisomant in acromegaly: an update

scientific article

Performance of Five Ultrasound Risk Stratification Systems in Selecting Thyroid Nodules for FNA

scientific article published on 01 May 2020

Pharmacologic agents for type 2 diabetes therapy and regulation of adipogenesis.

scientific article published on 31 May 2013

Postprandial glucose and HbA1c are associated with severity of obstructive sleep apnoea in non-diabetic obese subjects

scientific article published on 26 June 2021

Propensity-score-matched comparative analyses of simultaneously administered fixed-ratio insulin glargine 100 U and lixisenatide (iGlarLixi) vs sequential administration of insulin glargine and lixisenatide in uncontrolled type 2 diabetes

scientific article published on 13 August 2018

Prospective, randomized trial on intensive SMBG management added value in non-insulin-treated T2DM patients (PRISMA): a study to determine the effect of a structured SMBG intervention

scientific article published on 22 December 2011

RAS/BRAF mutational status in familial non-medullary thyroid carcinomas: A retrospective study.

scientific article published on 17 June 2015

Rare diseases in clinical endocrinology: a taxonomic classification system.

scientific article published on 7 November 2014

Reduced SIRT1 and SIRT2 expression promotes adipogenesis of human visceral adipose stem cells and associates with accumulation of visceral fat in human obesity

scientific article published on 28 August 2019

Reduction of hypoglycemia, lifestyle modifications and psychological distress during lockdown following SARS-CoV-2 outbreak in type 1 diabetic patients using flash continuous glucose monitoring: a retrospective cohort study

scientific article published on 11 September 2020

Regional differences of insulin action in adipose tissue: insights from in vivo and in vitro studies.

scientific article

Relationship between plasma sialic acid concentration and microvascular and macrovascular complications in type 1 diabetes: the EURODIAB Complications Study

scientific article

Renoprotection with SGLT2 inhibitors in type 2 diabetes over a spectrum of cardiovascular and renal risk

scientific article published on 22 November 2020

Response to comment on: Bosi et al. Intensive structured self-monitoring of blood glucose and glycemic control in noninsulin-treated type 2 diabetes: the PRISMA randomized trial. Diabetes Care 2013;36:2887-2894.

scientific article published on December 2013

Reversal of foetal hydrops and foetal tachyarrhythmia associated with maternal diabetic coma

scientific article published on 01 November 2000

Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma.

scientific article published on 19 July 2005

Role of UBC9 in the regulation of the adipogenic program in 3T3-L1 adipocytes

scientific article published on 29 September 2010

Role of the p66Shc isoform in insulin-like growth factor I receptor signaling through MEK/Erk and regulation of actin cytoskeleton in rat myoblasts

scientific journal article

Similar glycaemic control and less hypoglycaemia during active titration after insulin initiation with glargine 300 units/mL and degludec 100 units/mL: A subanalysis of the BRIGHT study

scientific article published on 20 December 2019

TNFα signals via p66(Shc) to induce E-Selectin, promote leukocyte transmigration and enhance permeability in human endothelial cells

scientific article

The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation provides a better definition of cardiovascular burden associated with CKD than the Modification of Diet in Renal Disease (MDRD) Study formula in subjects with type 2 diabetes

scientific article published on 6 May 2011

The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis

scientific article published on 02 March 2010

The IGF-I signaling pathway

scientific article published on January 2007

The Myokine Irisin Is Released in Response to Saturated Fatty Acids and Promotes Pancreatic β-Cell Survival and Insulin Secretion.

scientific article

The Role of Oxidative Stress in Cardiac Disease: From Physiological Response to Injury Factor

scientific article published on 14 May 2020

The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts

scientific journal article

The diabetic lung: an easy target for SARS-CoV-2?

scientific article published on 19 May 2020

The effects of weight loss due to gastric banding and lifestyle modification on red blood cell aggregation and deformability in severe obese subjects.

scientific article

The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.

scientific article

The p66Shc protein controls redox signaling and oxidation-dependent DNA damage in human liver cells

scientific article published on 3 September 2015

The sentrin-conjugating enzyme mUbc9 interacts with GLUT4 and GLUT1 glucose transporters and regulates transporter levels in skeletal muscle cells

scientific article

The ultrasound assessment of adipose tissue deposition in fetuses of "well controlled" insulin-dependent diabetic pregnancies

scientific article published in October 2003

Timing of fetal growth acceleration in women with insulin-dependent diabetes.

scientific article published in November 2003

Treatment of recent-onset type 1 diabetic patients with DiaPep277: results of a double-blind, placebo-controlled, randomized phase 3 trial

scientific article published in January 2014

Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling

scientific journal article

Urinary miRNA-27b-3p and miRNA-1228-3p correlate with the progression of Kidney Fibrosis in Diabetic Nephropathy

scientific article published on 06 August 2019

Vascular risk factors and markers of endothelial function as determinants of inflammatory markers in type 1 diabetes: the EURODIAB Prospective Complications Study

scientific article published in July 2003

Wound Healing in Diabetes: Hemorheological and Microcirculatory Aspects

scientific article published on 01 January 2011

Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes: Non Insulin Requiring Autoimmune Diabetes (NIRAD) 4.

scientific article

[Fetal growth restriction and insulin-like growth factors]

scientific article published on 01 January 2000

cDNA Cloning of the Rat IGF I Receptor: Structural Analysis of Rat and Human IGF I and Insulin Receptors Reveals Differences in Alternative Splicing and Receptor-Specific Domain Conservation

article

iGlarLixi effectively reduces residual hyperglycemia in patients with type 2 diabetes on basal insulin: a post hoc analysis from the LixiLan-L study

scientific article published on 03 May 2020

p66Shc, a multifaceted protein linking Erk signalling, glucose metabolism, and oxidative stress

scientific article published on 21 April 2011

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